Abstract: The present invention provides an electrochemical sensor that employs multiple electrode areas that are exposed for contact with a body fluid, e.g., when the sensor is inserted subcutaneously into a patient's skin. The exposed electrode areas are arranged symmetrically, such that a symmetrical potential distribution is produced when an AC signal is applied to the sensor. The sensors in accordance with these teachings can advantageously be used with AC signals to determine characteristics of the sensor and thus improve sensor performance. These teachings also provide a biocompatible sensor with multiple reference electrode areas that are exposed for contact with body fluid.

Abstract: The invention relates to a valve plug (1) for sealing a container opening, comprising a valve body (2) that can be placed on the container opening and is made of a first, rigid plastic material and a valve element (3) that is integrally connected to the valve body (2) and made of a second, elastic plastic material, which is more elastic than the first plastic material, wherein the valve element (3) has a sealing surface section (6) that can be placed in a sealing manner on a contact edge and a connecting part (8), which extends from a sealing surface section (6) radially through an opening in the valve body (2) to a retaining section (10) held on the outer circumference of the valve body, wherein the sealing surface section (6) is held by the connecting part without axial support of the sealing surface section (6).

Abstract: The present application relates to prodrug derivatives of 5-chloro-N-({(5S)-2-oxo-3-[4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene-2-carboxamide, processes for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially of thromboembolic disorders.

Abstract: A first tubular, inner radial annular seam is produced to weld together two hollow cylinders by narrow-gap tungsten inert gas arc welding. Narrow-gap metal gas-shielded arc welding is used to create another tubular, outer radial annular seam to further weld together both hollow cylinders. In this manner, the rotational axis of the rotor shaft remains vertically aligned throughout the entire production method of welding together the shaft parts. In this manner, the required production time can be advantageously reduced and the use of welding filler can be effectively decreased.

Abstract: The present invention relates to a skin patch comprising a matrix adhering to the skin and containing at least one active cosmetic substance and a combination with a skin wrapping to generate an effective compression for the treatment of cellulite and/or striae.

Abstract: Electrocoat materials comprising bismuth compounds, further comprising (A) at least one self-crosslinking and/or externally crosslinking binder containing (potentially) cationic or anionic groups and reactive functional groups which (i) with themselves or with complementary reactive functional groups in the self-crosslinking binder, or (ii) in the case of the externally crosslinking binder, with complementary reactive functional groups present in crosslinking agents (B) are able to undergo thermal crosslinking reactions, (B) if desired, at least one crosslinking agent comprising the complementary reactive functional groups, and (C) bismuth subsalicylate of empirical formula C7H5O4Bi.

Abstract: An ESD protection apparatus includes a substrate, a transistor structure arranged in the substrate, and a diode structure arranged in the substrate, a high-resistance electrical connection being provided between the transistor structure and the diode structure in the substrate.

Abstract: A multilayer paper tape including two or more paper sheets which are bonded by adhesive layers is described. Each of the top layer and the bottom layer of this stack of paper sheets and adhesive layers is an adhesive layer, around which, as a casing, is formed a folded paper sheet enclosing the stack of paper sheets and adhesive layers. This folded paper sheet is completely surrounded by an adhesive layer. A process for producing the same is also described.

Abstract: Disclosed herein is a polyol (A) based on modified amino resins, prepared by reacting: an amino resin (B) comprising three acetalized or etherified N-methylol groups of the general formula (I) >N—CHR—OR1, wherein R is a hydrogen atom, an alkyl group of 1 to 6 carbon atoms or an aryl group of 6 to 10 carbon atoms and R1 is an alkyl group of 1 to 6 carbon atoms; with a polyol (C) of the general formula (II) R2(—OH)n, wherein n is a number from 2 to 6 and R2 is a divalent to hexavalent organic radical; wherein an equivalent ratio of the acetalized or etherified N-methylol groups to the polyol (C) is 0.5:1 to 1.2:1; with elimination of at least 50 mol % of a monoalcohol (D) of the general formula R1—OH, wherein R1 is as defined above, from the amino resin (B).

Abstract: A side wall for a motor vehicle has an inside shell made of steel plate and an outside covering connected with (particularly welded to) the inside shell. The outside covering comprises an inside panel made of a steel alloy and an outside panel.

Abstract: A device for multi-photon fluorescence microscopy for obtaining information from biological tissue is provided. The device comprising a laser unit for generating an excitation radiation, an optical unit which is formed to focus the excitation radiation for generating an optical signal at different locations in or on an object to be examined, and a detector module for detecting the optical signal from the region of the object. The optical unit for generating the optical signal at different locations in or on the object is movable in at least one direction relative to the object.

Abstract: The present invention relates to immunotherapies that are based on myeloid cell depletion. In particular, the present invention relates to CD33 binding agents for use in such therapies, e.g. in the treatment of myeloid cell malignancies and myelodysplastic syndrome (MDS).

Abstract: A method of testing a fusion weld for a shaft includes producing two shaft subsections, wherein the shaft subsections are symmetrical and faun a cylinder coaxially along the axis of rotation. Core regions of each shaft subsection are removed in order to produce open recesses in the cylinder within remaining tubular webs. The two shaft subsections are positioned coaxially one on top of the other, wherein the two remaining webs are mutually adjacent and the two open recesses form a hollow space. A first tubular ring seam is produced by narrow-gap arc welding and in one of the two shaft subsections a passage from outside into the hollow space is produced. Further, a quality of the first tubular ring seam within the hollow space during and/or after the welding operation is evaluated by a detection device or radiation source which is introduced through the passage into the hollow space.

Abstract: Highly uniform cluster based nanocatalysts supported on technologically relevant supports were synthesized for reactions of top industrial relevance. The Pt-cluster based catalysts outperformed the very best reported ODHP catalyst in both activity (by up to two orders of magnitude higher turn-over frequencies) and in selectivity. The results clearly demonstrate that highly dispersed ultra-small Pt clusters precisely localized on high-surface area supports can lead to affordable new catalysts for highly efficient and economic propene production, including considerably simplified separation of the final product. The combined GISAXS-mass spectrometry provides an excellent tool to monitor the evolution of size and shape of nanocatalyst at action under realistic conditions. Also provided are sub-nanometer gold and sub-nanometer to few nm size-selected silver catalysts which possess size dependent tunable catalytic properties in the epoxidation of alkenes.

Abstract: The invention relates to a method for attaching guide means (106) to a flexible sheet (100), preferably as part of a shading system for a vehicle, and to a device provided therefor. Holding regions (102a, 102b), spaced apart from one another in a Y-direction, of a flexible sheet (100) extending in an X-direction and a Y-direction are spaced apart from one another by being acted upon with a predetermined pretensioning force (Fv) acting in the Y-direction, with the result that a pretension state is achieved. Subsequently, in a further processing state which corresponds to the pretension state or to a pretension state relieved by the amount of a predetermined relief distance (S3) in the Y-direction with respect to the pretension state, guide means (106) extending parallel to one another in the X-direction and spaced apart from one another in the Y-direction are fastened to the sheet (100).

Abstract: A process comprising applying coating materials to substrates, and curing the coating materials thermally and with actinic radiation, alone or together with optional coating films already present on the substrate. The actinic radiation cure is conducted under an oxygen-depleted atmosphere. The coating materials comprise (meth)acrylate copolymers having an OH number from 100 to 220 mg KOH/g, Tg of ?35 to +60° C., number-average MW of from 1,000 to 10,000 daltons and a mass-average MW of from 2,000 to 40,000 daltons and contain in copolymerized form an amount of hydroxyl-containing monomers (a) that corresponds to the OH number, of which (a1) from 20 to 90% by weight are based on (a), 4-hydroxybutyl(meth)acrylate and/or 2-alkylpropane-1,3-diol mono(meth)acrylate, and (a2) from 10 to 80% by weight are based on (a), other hydroxyl-containing olefinically unsaturated monomers. The process further comprises from 0.2 to 8% by weight of photoinitiators.

Abstract: A motor vehicle steering column includes a bracket fixed to the vehicle and a steering column tube. The steering column tube may be adjusted in inclination relative to the bracket fixed to the vehicle via an adjusting device. The adjusting device includes a lever which is mounted pivotably on the bracket and may be deflected about a pivot axis by a driving device. The motor vehicle steering column may permit a maximum inclination setting irrespective of the available construction space. A deflecting clamp which is connected pivotably to the steering column tube is coupled to an output end of the lever.

Abstract: A method for a safety system in a vehicle continuously evaluates data relating to the surroundings from a surroundings sensor system in terms of an imminent collision with an obstacle, and autonomous emergency braking is initiated in the event of an unavoidable collision. The emergency braking is maintained until a predefined event occurs. The predefined event can be the expiration of a time calculated in advance up to the collision or the impact which is actually detected by a sensor.

Abstract: A diagnostic device as a first electrode formed by a noble metal that is not attackable by acid, and a second electrode that is formed of silver. The first and second electrodes are at least partially immersed in a nutrient solution contained in a container, into which a tissue sample can be introduced. An electrical voltage is applied between the first and second electrodes, and a change in an electrical variable between the electrodes is measured when ammonia is present. The diagnostic device allows fast screening of tissue samples for Helicobacter pylori.

Abstract: Textile treatment agent containing a biocidal compound, a perfume composition and a non-ionic surfactant, wherein the non-ionic surfactant has an HLB value of from 10.5 to 15 and a cloud temperature of at least 50° C. This allows production of a stable textile treatment agent which reduces the number of microorganisms on textiles treated with the agent and gives the textiles a pleasant fragrance.