Abstract: The present invention includes a method for representing a plurality of pre-calculated solutions in radiation therapy that are stored in a database and displayed in a manner controllable by a user. Arrays of DVH curves provide the user with essential information on the ‘quality of a plan’. A DVH diagram is displayed as a main diagram, wherein only one of the solutions is visually represented at a time. By selecting a first starting point on a selected DVH curve as the main diagram, a first straight axis extending through the first starting point is placed. A first region, located around the first starting point and on the first straight axis, is highlighted as a first control region for controllable visualization of the plurality of currently non-displayed solutions stored in the database, the DVH curves of which correspond to the selected DVH curve and intersect the first straight axis.

Abstract: To achieve a general improvement in the driving stability of a motor vehicle, it is proposed to control the driving stability of the motor vehicle based on a continuously determined environment model, wherein the environment model is used for predictive adaptation of existing vehicle dynamics control systems.

Abstract: The present application relates to novel substituted 4-aryl-1,4-dihydro-1,6-naphthyridine-3-carboxamides, a process for their preparation, their use for the treatment and/or prophylaxis of diseases, and their use for the manufacture of medicaments for the treatment and/or prophylaxis of diseases, especially cardiovascular disorders.

Abstract: The present invention relates to the use of a polyurethane adhesive in the manufacture of film/foil-coated furniture. The adhesive consists of two components, the first component comprising at least two different polyurethanes which comprise carboxyl groups, and the polyurethanes comprising units derived from polyester diols and units derived from polyether diols, the weight quantity ratio of the sum total of all units derived from polyester diols to the sum total of all units derived from polyether diols being in the range from 1:9 to 9:1, and the second component comprising at least one silane compound reactive toward carboxyl groups.

Abstract: The invention relates to a spectacle lens semi-finished or finished product with a front surface, a rear surface, a cylinder rim surface, a front edge surface with a front surface transition to the front surface and a front cylinder rim surface transition to the cylinder rim surface and/or a rear edge surface with a rear surface transition to the rear surface and a rear cylinder rim surface transition to the cylinder rim surface. The front surface transition is formed as a rounding and/or the rear surface transition is formed as a rounding.

Abstract: The present application relates to novel substituted 2-(piperidin-1-yl)acetamide derivatives, to processes for preparation thereof, to the use thereof for treatment and/or prevention of diseases, and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of cardiovascular diseases.

Abstract: The present invention relates to a novel process for the production of novel fibre-reinforced profile materials comprising a PMI foam core. In particular, the present invention relates to a novel pultrusion process, the abbreviated term used for which is pul-core process, which uses a single step for production of the fibre-reinforced profile material with simultaneous charging of the PMI foam core thereto. The same step here ensures very good linkage of the PMI foam core to the fibre-reinforced profile material.

Abstract: An apparatus for position determination has an optical scanning unit which is to be moved relative to a surface and which includes an image sensor for detecting light intensity patterns of light which is reflected by the surface. The apparatus furthermore has an electronic processing unit which is associated with the image sensor and configured to determine a traveled movement path and/or a movement speed of the optical scanning unit relative to the surface from a difference between light intensity patterns detected after one another in time. A further processing unit is configured to produce an intensity correlated signal which correlates with the intensity of the light reflected by the surface. An evaluation device is associated with the image sensor and is configured to recognize a graphical code pattern located on the surface with reference to the intensity correlated signal and to read out information from the code pattern.

Abstract: A continuously operating casting and rolling system with a strip tension control includes a casting unit having a melt-containing feed vessel with a horizontal casting channel and a discharge region in the form of a casting nozzle, and a primary cooling zone with two guide rolls and a circulating cooled casting strip and at least one downstream rolling unit having at least two drivable rollers. In order to minimize the tension on the cast strip, the casting unit and the subsequent rolling unit are mechanically decoupled, wherein for the decoupling at least one driver unit having at least two drivable rollers for driving the strip is arranged between the casting belt and the rolling unit.

Abstract: The invention relates to a connection device (27) comprising a coupling device (24) and a plug element (34) for a welding torch (10) connected to the coupling device (24) by at least one hose assembly (23), said coupling device arranged at least partially in the housing, wherein a welding wire (13), delivered by a feed unit (29) which is arranged on a motor plate (28), and additional media are conducted to the welding torch (10) via the hose assembly (23) and wherein the hose assembly (23) is connected to the plug element (34). In order to create such a connection system (27), the coupling device is formed by a connection device (30) comprising an end wall (38) and a separating wall (39) of the motor plate (28), wherein the end wall (38) is designed to receive the coupling (35), the connection device (30) is constructed to at least guide and position a pin (37), and the connection device (30) is independent of the housing.

Abstract: This invention relates to novel 5-[(hydroxymethyl)aryl]-substituted pyrrolo[2,1-f][1,2,4]triazin-4-amines of formula (I), to processes for the preparation of such compounds, to pharmaceutical compositions containing such compounds, and to the use of such compounds or compositions for treating angiogenesis-related disorders, in particular angiogenesis-related ocular disorders.

Abstract: The invention concerns the production of quinoline compounds containing sulfonic acid groups, the said quinoline compounds and their conversion into dyes containing sulfonic acid groups. The dyes according to the invention are used especially to label analytes, for example to label biomolecules.

Abstract: The present invention relates to a process for heat integration in the preparation of saturated C3-C20-alcohols, in which a hydrogenation feed comprising at least one C3-C20-aldehyde is hydrogenated in the presence of a hydrogen-comprising gas in a hydrogenation zone and a discharge is taken off from the hydrogenation zone and subjected to distillation in at least one distillation column to give a fraction enriched in saturated C3-C20-alcohols.

Abstract: A Compton radiation detection device for determining of Compton radiation of iron, includes a sensor and a filter arrangement. The filter arrangement is adapted such that the radiation emitted by a test object due to Compton scattering passes a nickel layer and an iron layer before being detected by the sensor. A dispersive ionization chamber includes an ionization chamber having a plurality off ionization volumes and a window. Each ionization volume includes an electrode. Radiation can enter through the window. The ionization volumes are arranged in a beam propagation direction behind each other. Radiation having lower energy is statistically absorbed in ionization volumes located more proximal to the window. Radiation having higher energy is statistically absorbed in the ionization volumes located more distal from the window.

Abstract: An ion-conductive thermoplastic compositions contains a partially acetalated polyvinyl alcohol, at least one support electrolyte and at least one plasticizer. The partially acetalated polyvinyl alcohol contains two different acetal units. Electrochromic laminated glass systems produced using the ion-conductive compositions and a method for producing the systems are also provided.

Abstract: An actuator, especially for a vehicle protection system, comprises at least one wire (14) variable in shape depending on temperature made from a shape memory alloy and an elongate pyrotechnical element (12) connected to the shape-variable wire (14) so that upon ignition of the pyrotechnical element (12) the wire (14) is heated and experiences a change of length. The vehicle protection system is, for example, an airbag system comprising an airbag and a regulating mechanism for the internal airbag pressure, wherein the wire (14) of the actuator (10) is connected to the regulating mechanism so that a change of shape of the wire (14) exerts a force on the regulating mechanism.

Abstract: A process for the preparation of alkoxysilyl group-containing isocyanate compounds which includes the step of reacting carbonyl chloride ClC(?O)Cl with an alkoxysilyl group-containing amine in the presence of a high boiling point base, and optionally in the presence of an inert organic solvent, in order to minimize by product production and to simplify product purification, is disclosed.

Abstract: The present invention relates to 5-oxoisoxazole derivatives of the formula I, the pharmaceutically usable salts thereof and the use thereof as medicinal substances.

Abstract: The present application relates to novel substituted (aza)pyridopyrazolopyrimidinones and indazolopyrimidinones, to processes for their preparation, the compounds for use alone or in combinations in a method for the treatment and/or prophylaxis of diseases, in particular for the treatment and/or prophylaxis of acute and recurrent bleeding in patients with or without underlying hereditary or acquired bleeding disorders, wherein the bleeding is associated with a disease or medical intervention selected from the group consisting of menorrhagia, postpartum hemorrhage, hemorrhagic shock, trauma, surgery, transplantation, stroke, liver diseases, hereditary angioedema, nosebleed, and synovitis and cartilage damage following hemarthrosis.

Abstract: The present invention relates to pharmaceutical combinations CD33 antibodies and de-methylating agents for use in treating diseases like MDS and cancer, especially AML.