Abstract: The present invention is further directed to methods and compositions for modulating the activity of the Toso protein. The invention further encompasses treatment of disorders associated with inflammation, autoimmune disorders, and cancer using compositions that include a soluble Toso protein.

Abstract: The present invention is further directed to methods and compositions for modulating the activity of the Toso protein. The invention further encompasses treatment of disorders associated with inflammation, autoimmune disorders, and cancer using compositions that include a soluble Toso protein.

Abstract: Described are techniques and systems for providing a user interface which provides information about one or more activities being performed by services available among affiliated devices. The information is based on activity data which may be obtained through a subscription-publication mechanism with the affiliated devices. The user interface may also provide activity controls to modify the one or more activities.

Abstract: The present invention is further directed to methods and compositions for modulating the activity of the Toso protein. The invention further encompasses treatment of disorders associated with inflammation, autoimmune disorders, and cancer using compositions that include a soluble Toso protein.

Abstract: Print performance is evaluated by printing a diagnostic image comprising color patches. Colorant usage in the printed image is measured by, for instance, scanning each patch. Measured color values are then compared to target color values. Based on the comparison, groups of patches whose color values vary significantly from expectations are identified. Variant groups are then analyzed to identify, in addition to color quality control problems, spatial problems that affect only a localized area of a printed page. Such spatial problems may include, for example, problems with contrast or streaks. A heat map illustrating the differences may be generated to help an operator visualize the spatial problem. A template for the diagnostic image may be selected from a plurality of randomly generated diagnostic targets based on total colorant usage for at least one colorant in each column of color patches. Certain patches may be predefined across for each candidate target.

Abstract: The present invention relates to a compound of formulas I, Ia, Ib and II, wherein R1 to R11 are herein defined.

Abstract: Print performance is evaluated by printing a diagnostic image comprising color patches. Colorant usage in the printed image is measured by, for instance, scanning each patch. Measured color values are then compared to target color values. Based on the comparison, groups of patches whose color values vary significantly from expectations are identified. Variant groups are then analyzed to identify, in addition to color quality control problems, spatial problems that affect only a localized area of a printed page. Such spatial problems may include, for example, problems with contrast or streaks. A heat map illustrating the differences may be generated to help an operator visualize the spatial problem. A template for the diagnostic image may be selected from a plurality of randomly generated diagnostic targets based on total colorant usage for at least one colorant in each column of color patches. Certain patches may be predefined across for each candidate target.

Abstract: The present invention relates to a compound of the formula I, Ia and Ib, and its pharmaceutically usable tautomers, salts, stereoisomers and the enantiomers, including mixtures thereof in all ratios.

Abstract: An analyzer system has an instrument holder that can hold at least two instruments and is movable along a vertical guide. At least one washing device is provided for the instruments, with one or more jet orifices fed by a supply conduit to spray wash fluid at the instruments. The washing device comprises one or more wash rings surrounding the instruments. The washing device is separate from and movable in relation to the instrument holder, and the one or more jet orifices are aimed at the instruments positioned inside the one or more wash rings.

Abstract: The present invention relates to a method of treating hepatitis comprising administering a serotonin blocker, and the use of such blockers in said treatment and in the manufacture of medicaments for treating hepatitis.

Abstract: The invention relates to the use of a substance for the diagnostic detection of Sgk, especially Sgk1 and/or Sgk3, and/or PKB and/or Nedd, especially Nedd4-2, and to the use of active ingredients which influence glucose transport for treating diseases associated with disturbed glucose transport, and for fattening animals. The invention also relates to a diagnosis kit and a pharmaceutical composition comprising an active quantity of at least one active ingredient which influences glucose transport. The invention further relates to a method for producing transgenic animals.

Abstract: A color calibration system includes a visual display terminal (VDT), a color calibration sensor optically coupled to the VDT, and a computer processing unit (CPU) electrically coupled to the VDT and the color calibration sensor. The VDT has a display screen and a plurality of color channels, each color channel having an intensity input, a bias input, and a gain input. The VDT produces an image on the display screen responsive to the intensity input. The color calibration sensor provides values responsive to the chromaticity and luminance of a test patch portion of the image on the display screen. The CPU performs calibration of the VDT including setting the bias of each color channel to reduce the difference between a target black point and the test patch with the intensity input at a minimum value for each color channel.

Abstract: A color calibration system includes a visual display terminal (VDT), a color calibration sensor optically coupled to the VDT, and a computer processing unit (CPU) electrically coupled to the VDT and the color calibration sensor. The VDT has a display screen and a plurality of color channels, each color channel having an intensity input, a bias input, and a gain input. The VDT produces an image on the display screen responsive to the intensity input. The color calibration sensor provides values responsive to the chromaticity and luminance of a test patch portion of the image on the display screen. The CPU performs calibration of the VDT including setting the bias of each color channel to reduce the difference between a target black point and the test patch with the intensity input at a minimum value for each color channel.

Abstract: A laboratory analyzer system has a base housing (1) on which a sample tray (4) with holding accommodations (5) for two or more samples is movably supported. A drive mechanism (2) inside the base housing advances the sample tray in a stepwise motion so that the samples are presented one by one to a tower-like analytical instrument module (16, 16′) that is installed on the base housing. The mounting arrangement for the analytical instrument module on the base housing is non-destructively releasable, with first connector elements (15) arranged at multiple locations on the base housing and second connector elements on the analytical instrument module. The multiple first connector elements offer the possibilities of installing more than one analytical instrument module on the base housing as well as installing a single instrument module at a choice of different locations on the base housing.

Abstract: An analyzer system has an instrument holder that can hold at least two instruments and is movable along a vertical guide. At least one washing device is provided for the instruments, with one or more jet orifices fed by a supply conduit to spray wash fluid at the instruments. The washing device comprises one or more wash rings surrounding the instruments. The washing device is separate from and movable in relation to the instrument holder, and the one or more jet orifices are aimed at the instruments positioned inside the one or more wash rings.

Abstract: There has been found1) a method for reducing the toxicity of spent liquors from dyeing with cationic dyes or mixtures thereof, characterized by the step of dyeing with cationic dyes having a computed electrostatic shielding energy (idealized hydration energy) of .gtoreq.50 kcal/mol,2) cationic, generally low toxicity dyes, their preparation and use for dyeing.

Abstract: A device for charging a measuring apparatus for thermal analysis with material specimens filled into containers includes a vertically displaceable gripping member and a rotatable specimen plate with a plurality of openings arranged in a circle. For transferring a specimen container to the measuring location in the measuring apparatus, the specimen container is moved underneath the gripping member by rotating the specimen plate, the gripping member is lowered and the specimen container is gripped by gripping fingers attached to the gripping member. The container is then raised from the specimen plate by raising the gripping member. Subsequently, the specimen plate is rotated until a recess in the specimen plate is located underneath the gripping member. The measuring location is also located directly underneath the gripping member.

Abstract: A short-circuiting and brush-lifting device comprises a rotatable actuating ring having with brush-actuating rods levers cause the brushes of the motor to lift up via the rotating actuating after the slip rings have been short-circuited as a result of the axial displacement of a short-circuiting ring. To make the device wear-resistant and insensitive to contamination, the actuating ring supports three rollers, with which it abuts in the starting position on the spring-loaded short-circuiting ring. The actuating ring is guided exactly in parallel by three axial guide rods, which are disposed perpendicularly to the brush-actuating rods. The configuration of all articulated joints of these rods is adjusted so as to allow the points of maximum excursion of the deflection of the articulated joint of the axial guide rods and the brush-actuating rods are exhibited at staggered times.

Abstract: In a self-ventilated electrical machine with vertical shaft, the ventilator is centered and releasably fastened to a hub on the rotor shaft below the stack of rotor plates. The ventilator must be detached from the hub before it can be removed from the housing of the machine. To facilitate assembly and dismantling of the ventilator disk on the hub, the hub has an annular protuberance which can be gripped radially from behind. At least three mobile clamping pieces are distributed uniformly around its circumference and can be engaged by interlocking or friction. The clamping pieces are carried by the ventilator disk and at least one limit stop for each clamping piece is arranged on the holding device for each clamping piece. This clamping connection of the ventilator to the hub of the rotor shaft is particularly suitable for self-ventilated high-voltage motors with high output and with a vertical rotor shaft.

Abstract: Buret apparatus of the type including a buret conduit terminating at one end in a siphon, characterized in that the siphon includes a siphon passage formed on a stopper that is removably mounted in the buret conduit. The improved siphon structure is relatively inexpensive to manufacture, and is less susceptible to breakage than the conventional circular glass siphon devices. The improved apparatus is particularly suitable for use as a precision titrator or dosing device where measurements in the microliter range are required.