Patents by Inventor Karsten Matthias

Karsten Matthias has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11525151
    Abstract: Described are methods for saccharifying starch-containing materials using a glucoamylase, methods for producing fermentation products, and fermentation products produced by the method thereof as well as methods for increasing starch digestibility in a ruminant using at least one of the glucoamylases described herein.
    Type: Grant
    Filed: March 6, 2019
    Date of Patent: December 13, 2022
    Assignee: DANISCO US INC.
    Inventors: Jing Ge, Xiaogang Gu, Helong Hao, Karsten Matthias Kragh, Jinahua (Jalsen) Li, Wenting Li, Zhongmei Tang, Shukun Yu, Bo Zhong, Kun Zhong, Zhengzheng Zou
  • Patent number: 11473073
    Abstract: The present disclosure provides polypeptides having aminopeptidase activity and isolated nucleic acid sequences encoding the polypeptides. In some embodiments, the disclosure also provides to nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as methods for producing the polypeptides. In some embodiments, the present disclosure further provides to methods of obtaining protein hydrolysates useful as flavor improving agents.
    Type: Grant
    Filed: June 27, 2016
    Date of Patent: October 18, 2022
    Assignee: Dupont Nutrition Biosciences APS
    Inventors: Karsten Matthias Kragh, Ernst Meinjohanns, Thomas Eisele, Peter Edvard Degn, Steffen Yde Bak
  • Publication number: 20220264911
    Abstract: Provided herein, inter alia, are granules for inclusion in feed or feed additive compositions as well as methods for making and using the same for improving the performance of a ruminant animal with respect to one or more of improved feed conversion ratio (FCR), improved weight gain, improved feed efficiency, improved carcass quality, and/or improved milk production.
    Type: Application
    Filed: July 9, 2020
    Publication date: August 25, 2022
    Inventors: Shukun YU, Kathryn Louise TSE, Wenting LI, Leon MARCHAL, Jouni VILJANEN, Karsten Matthias KRAGH, Charlotte HORSMANS POULSEN
  • Publication number: 20220174981
    Abstract: A method for the production of a hydrolysate comprising: (a) admixing at least one protein or a portion thereof with: (A) at least one endoprotease; and (B) (a?) at least one proline tolerant tripeptidyl peptidase or fermentate comprising a proline tolerant tripeptidyl peptidase predominantly having exopeptidase activity wherein said proline tolerant tripeptidyl peptidase is capable of cleaving tri-peptides from the N-terminus of peptides having: Proline at P1; and synthetic amino acids at P1; or (b?) at least one proline tolerant tripeptidyl peptidase having exopeptidase activity wherein said proline tolerant tripeptidyl peptidase is capable of cleaving tri-peptides from the N-terminus of peptides having: Proline at PV; and synthetic amino acids at PV; and (b) recovering the hydrolysate.
    Type: Application
    Filed: November 24, 2021
    Publication date: June 9, 2022
    Applicant: DuPont Nutrition Biosciences APS
    Inventors: Karsten Matthias KRAGH, Ernst MEINJOHANNS, Andrei MIASNIKOV, Maria MA, Thomas EISELE, Svend HAANING, Peter Edvard DEGN, Steffen Yde BAK
  • Publication number: 20220162657
    Abstract: Described are methods for saccharifying starch-containing materials using a glucoamylase, methods for producing fermentation products, and fermentation products produced by the method thereof as well as methods for increasing starch digestibility in a ruminant using at least one of the glucoamylases described herein.
    Type: Application
    Filed: December 7, 2021
    Publication date: May 26, 2022
    Inventors: Jing Ge, Xiaogang Gu, Helong Hao, Karsten Matthias Kraugh, Jinahua (Jalsen) Li, Wenting Li, Zhongmei Tang, Shukun Yu, Bo Zhang, Kun Zhong, Zhengzheng Zou
  • Publication number: 20220136027
    Abstract: The present invention related to a method for preparing a protein hydrolysate from a proteinaceous material by contacting the material with a proteolytic enzyme mixture having a proline specific exopeptidase. In particular, the proline specific exopeptidase is an aminopeptidase specific for at the five amino acid N-terminal sequence X-Pro-Gln-Glv-Pro-, where X is any amino acid. The present invention also relates to use of the aminopeptidase with a second exopeptidase and an endopeptidase.
    Type: Application
    Filed: February 25, 2020
    Publication date: May 5, 2022
    Inventors: Peter Edvard DEGN, Xiaogang GU, Karsten Matthias KRAGH, Robin Anton SORG, Steffen Yde BAK, Svend HAANING, Xinyue TANG, Helong HAO, Marc Anton Bernhard KOLKMAN
  • Publication number: 20210360937
    Abstract: The present invention relates to the solubilisation of cereal bran, for preparing compositions comprising soluble fractions of cereal bran and the use of these compositions comprising solubilised cereal bran for the preparation of food products, such as bread.
    Type: Application
    Filed: June 3, 2021
    Publication date: November 25, 2021
    Applicant: DUPONT NUTRITION BIOSCIENCES APS
    Inventors: JENS FRISBAEK SØRENSEN, RENE MIKKELSEN, CHARLOTTE HORSMANS POULSEN, KARSTEN MATTHIAS KRAGH
  • Publication number: 20210315238
    Abstract: The present invention provides proline specific endopeptidases. The present invention further provides methods for use of proline specific endopeptidases for use in reduction of chill haze in a beverage, including beer. The present invention further provides methods for producing protein hydrolysates using proline specific endopeptidases. Also provided are methods of treating disease, including Celiac disease using proline specific endopeptidases. Also provided are nucleic acids encoding the proline specific endopeptidases and host cells for production of the proline specific endopeptidases.
    Type: Application
    Filed: July 31, 2019
    Publication date: October 14, 2021
    Inventors: Xiaogang GU, Karsten Matthias KRAGH, Ernest MEINJOHANNS, Xinyue TANG
  • Publication number: 20210299229
    Abstract: Disclosed are uses at least one alpha-1,4/1,6-glycoside hydrolase (GLCH) as a feed additive for a ruminant wherein said hydrolase: (a) has at least 20% activity at pH less than or equal to 3 in the presence of pepsin as compared to activity of the hydrolase at pH 6 in the presence of pepsin, (b) said hydrolase is active in at least two of three digestive chambers of a ruminant comprising a rumen, an abomasum and a small intestine and (c) the hydrolase works with pancreatic amylase to increase glucose yield.
    Type: Application
    Filed: September 15, 2017
    Publication date: September 30, 2021
    Inventors: Shukun Yu, Karsten Matthias Kragh, Wenting Li
  • Publication number: 20210120845
    Abstract: The present invention relates to compositions and methods for the production of a hydrolysate comprising at least one endoprotease and a tripeptidyl peptidase capable of cleaving tripeptides from the N-terminus a peptide and/or proteins having one or more of lysine, arginine or glycine in the P1 position wherein said tripeptidyl peptidase is capable of being used at a temperature between 45° C. and 70° C.
    Type: Application
    Filed: February 21, 2017
    Publication date: April 29, 2021
    Inventors: Karsten Matthias Kragh, Svend Haaning, Ernst Meinjohanns, Peter Edvard Degn, Steffan Yde Bak, Thomas Eisele
  • Publication number: 20210040523
    Abstract: Described are methods for saccharifying starch-containing materials using a glucoamylase, methods for producing fermentation products, and fermentation products produced by the method thereof as well as methods for increasing starch digestibility in a ruminant using at least one of the glucoamylases described herein.
    Type: Application
    Filed: March 6, 2019
    Publication date: February 11, 2021
    Inventors: Jing Ge, Xiaogang Gu, Helong Hao, Karsten Matthias, Jinahua (Jalsen) Li, Wenting Li, Zhongmei Tang, Shukun Yu, Bo Zhong, Kun Zhong, Zhengzheng Zou
  • Publication number: 20200383352
    Abstract: The present disclosure provides methods and uses for keratin hydrolysates (e.g. feathers hydrolysates).
    Type: Application
    Filed: February 3, 2020
    Publication date: December 10, 2020
    Inventors: JON GADE HANSTED, KARSTEN MATTHIAS KRAGH, STEPAN SHIPOVSKOV, SHUKUN YU
  • Publication number: 20200245642
    Abstract: A method of preparing a feed additive composition comprising: (a) admixing at least one proline tolerant tripeptidyl peptidase predominantly having exopeptidase activity wherein said proline tolerant tripeptidyl peptidase is capable of cleaving tri-peptides from the N-terminus of peptides having (i) (A) Proline at P1; and (B) An amino acid selected from alanine, arginine, asparagine, aspartic acid, cysteine, glutamine, glutamic acid, glycine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, serine, threonine, tryptophan, tyrosine, valine or synthetic amino acids at P1; or (ii) (a?) Proline at PV; and (b?) An amino acid selected from alanine, arginine, asparagine, aspartic acid, cysteine, glutamine, glutamic acid, glycine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, serine, threonine, tryptophan, tyrosine, valine or synthetic amino acids or amines at PV; and one or more ingredients selected from the group consisting of a salt, polyol including sorbitol and glycerol, whe
    Type: Application
    Filed: January 16, 2020
    Publication date: August 6, 2020
    Inventors: SVEND HAANING, KARSTEN MATTHIAS KRAGH, STEPAN SHIPOVSKOV, ANDREI MIASNIKOV, MARIA MA, LUIS FERNANDO ROMERO MILLAN, LUKE BARNARD, SHUKUN YU, ERNST MEINJOHANNS, STEFFEN YDE BAK, PÄIVI NURMINEN, HELI ANGLENIUS
  • Publication number: 20200236974
    Abstract: Disclosed are methods for improving the digestibility of high-moisture grain feed and/or rehydrated grain feed for animals which comprises a) processing the grain feed into fragments and b) contacting the grain feed fragments of step (a) with at least one starch hydrolase which is stable and active at a pH less than 5.0, optionally at least one protease, in combination with at least one inoculant comprising at least one bacterial strain.
    Type: Application
    Filed: July 18, 2018
    Publication date: July 30, 2020
    Inventors: Shukun Yu, Karsten Matthias Kragh
  • Publication number: 20200221715
    Abstract: The present invention relates to the solubilisation of cereal bran, for preparing compositions comprising soluble fractions of cereal bran and the use of these compositions comprising solubilised cereal bran for the preparation of food products, such as bread.
    Type: Application
    Filed: March 24, 2020
    Publication date: July 16, 2020
    Inventors: Jens Frisbaek SØRENSEN, Rene Mikkelsen, Charlotte Horsmans Poulsen, Karsten Matthias Kragh
  • Publication number: 20190223456
    Abstract: The present invention relates to the solubilisation of cereal bran, for preparing compositions comprising soluble fractions of cereal bran and the use of these compositions comprising solubilised cereal bran for the preparation of food products, such as bread.
    Type: Application
    Filed: April 3, 2019
    Publication date: July 25, 2019
    Inventors: JENS FRISBAEK SØRENSEN, RENE MIKKELSEN, CHARLOTTE HORSMANS POULSEN, KARSTEN MATTHIAS KRAGH
  • Publication number: 20180295858
    Abstract: A method of preparing a feed additive composition comprising: (a) admixing at least one proline tolerant tripeptidyl peptidase predominantly having exopeptidase activity wherein said proline tolerant tripeptidyl peptidase is capable of cleaving tri-peptides from the N-terminus of peptides having (i) (A) Proline at P1; and (B) An amino acid selected from alanine, arginine, asparagine, aspartic acid, cysteine, glutamine, glutamic acid, glycine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, serine, threonine, tryptophan, tyrosine, valine or synthetic amino acids at P1; or (ii) (a?) Proline at P1?; and (b?) An amino acid selected from alanine, arginine, asparagine, aspartic acid, cysteine, glutamine, glutamic acid, glycine, histidine, isoleucine, leucine, lysine, methionine, phenylalanine, serine, threonine, tryptophan, tyrosine, valine or synthetic amino acids or amines at P1?; and one or more ingredients selected from the group consisting of a salt, polyol including sorbitol and glycerol, w
    Type: Application
    Filed: October 23, 2015
    Publication date: October 18, 2018
    Inventors: Svend Haaning, Karsten Matthias Kragh, Stepan Shipovskov, Andrei Miasnikov, Maria Ma, Luis Fernando Romero Millan, Luke Barnard, Shukun Yu, Ernst Meinjohanns, Steffen Bak, Päivi Nurminen, Heli Putaala
  • Publication number: 20180291360
    Abstract: The present disclosure provides polypeptides having aminopeptidase activity and isolated nucleic acid sequences encoding the polypeptides. In some embodiments, the disclosure also provides to nucleic acid constructs, vectors, and host cells comprising the nucleic acid sequences as well as methods for producing the polypeptides. In some embodiments, the present disclosure further provides to methods of obtaining protein hydrolysates useful as flavor improving agents.
    Type: Application
    Filed: June 27, 2016
    Publication date: October 11, 2018
    Inventors: Karsten Matthias Kragh, Ernst Meinjohanns, Thomas Eisele, Peter Edvard Degn, Steffen Yde Bak
  • Publication number: 20180263259
    Abstract: The present disclosure provides methods and uses for keratin hydrolysates (e.g. feathers hydrolysates).
    Type: Application
    Filed: January 7, 2016
    Publication date: September 20, 2018
    Inventors: Jon Gade, KARSTEN MATTHIAS KRAGH, Stepan Shipovskov, Shukun Yu
  • Publication number: 20170325479
    Abstract: A method for the production of a hydrolysate comprising: (a) admixing at least one protein or a portion thereof with: (A) at least one endoprotease; and (B) (a?) at least one proline tolerant tripeptidyl peptidase or fermentate comprising a proline tolerant tripeptidyl peptidase predominantly having exopeptidase activity wherein said proline tolerant tripeptidyl peptidase is capable of cleaving tri-peptides from the N-terminus of peptides having: Proline at P1; and synthetic amino acids at P1; or (b?) at least one proline tolerant tripeptidyl peptidase having exopeptidase activity wherein said proline tolerant tripeptidyl peptidase is capable of cleaving tri-peptides from the N-terminus of peptides having: Proline at PV; and synthetic amino acids at PV; and (b) recovering the hydrolysate.
    Type: Application
    Filed: October 23, 2015
    Publication date: November 16, 2017
    Applicant: DuPont Nutrition Biosciences APS
    Inventors: Karsten Matthias KRAGH, Ernst MEINJOHANNS, Andrei MIASNIKOV, Maria MA, Thomas EISELE, Svend HAANING, Peter Edvard DEGN, Steffen Yde BAK