Patents by Inventor Karthik Ganesan

Karthik Ganesan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10466160
    Abstract: A system and method for isolating and analyzing single cells, including: a substrate having a broad surface; a set of wells defined at the broad surface of the substrate, and a set of channels, defined by the wall, that fluidly couple each well to at least one adjacent well in the set of wells; and fluid delivery module defining an inlet and comprising a plate, removably coupled to the substrate, the plate defining a recessed region fluidly connected to the inlet and facing the broad surface of the substrate, the fluid delivery module comprising a cell capture mode.
    Type: Grant
    Filed: November 16, 2017
    Date of Patent: November 5, 2019
    Assignee: Celsee Diagnostics, Inc.
    Inventors: Kalyan Handique, Austin Payne, Vishal Sharma, Kyle Gleason, Priyadarshini Gogoi, Karthik Ganesan, Brian Boniface, Will Chow
  • Publication number: 20190331765
    Abstract: A radar hardware accelerator (HWA) includes a fast Fourier transform (FFT) engine including a pre-processing block for providing interference mitigation and/or multiplying a radar data sample stream received from ADC buffers within a split accelerator local memory that also includes output buffers by a pre-programmed complex scalar or a specified sample from an internal look-up table (LUT) to generate pre-processed samples. A windowing plus FFT block (windowed FFT block) is for multiply the pre-processed samples by a window vector and then processing by an FFT block for performing a FFT to generate Fourier transformed samples. A post-processing block is for computing a magnitude of the Fourier transformed samples and performing a data compression operation for generating post-processed radar data. The pre-processing block, windowed FFT block and post-processing block are connected in one streaming series data path.
    Type: Application
    Filed: June 14, 2019
    Publication date: October 31, 2019
    Inventors: Sandeep Rao, Karthik Ramasubramanian, Indu Prathapan, Raghu Ganesan, Pankaj Gupta
  • Patent number: 10351901
    Abstract: A microfluidic processing device includes a substrate defining a microfluidic network. The substrate is in thermal communication with a plurality of N independently controllable components and a plurality of input output contacts for connecting the substrate to an external controller. Each component has at least two terminals. Each terminal is in electrical communication with at least one contact. The number of contacts required to independently control the N components is substantially less than the total number of terminals. Upon actuation, the components typically heat a portion of the microfluidic network and/or sense a temperature thereof.
    Type: Grant
    Filed: June 12, 2017
    Date of Patent: July 16, 2019
    Assignee: HandyLab, Inc.
    Inventors: Karthik Ganesan, Kalyan Handique
  • Patent number: 10330773
    Abstract: A radar hardware accelerator (HWA) includes a fast Fourier transform (FFT) engine including a pre-processing block for providing interference mitigation and/or multiplying a radar data sample stream received from ADC buffers within a split accelerator local memory that also includes output buffers by a pre-programmed complex scalar or a specified sample from an internal look-up table (LUT) to generate pre-processed samples. A windowing plus FFT block (windowed FFT block) is for multiply the pre-processed samples by a window vector and then processing by an FFT block for performing a FFT to generate Fourier transformed samples. A post-processing block is for computing a magnitude of the Fourier transformed samples and performing a data compression operation for generating post-processed radar data. The pre-processing block, windowed FFT block and post-processing block are connected in one streaming series data path.
    Type: Grant
    Filed: June 16, 2016
    Date of Patent: June 25, 2019
    Assignee: TEXAS INSTRUMENTS INCORPORATED
    Inventors: Sandeep Rao, Karthik Ramasubramanian, Indu Prathapan, Raghu Ganesan, Pankaj Gupta
  • Publication number: 20180260323
    Abstract: A heterogeneous memory system is implemented using a low-latency near memory (NM) and a high-latency far memory (FM). Pages in the memory system include NM blocks stored in the NM and FM blocks stored in the FM. A page is assigned to a region in the memory system based on the proportion of NM blocks in the page. When accessing a block, the block address is used to determine a region of the memory system, and a block offset is used to determine whether the block is stored in NM or FM. The memory system may observe memory accesses to determine the access statistics of the page and the block. Based on a page's hotness and access density, the page may be migrated to a different region. Based on a block's hotness, the block may be migrated between NM and FM allocated to the page.
    Type: Application
    Filed: December 22, 2017
    Publication date: September 13, 2018
    Inventors: Lizy John, Jee Ho Ryoo, Hung-Ming Hsu, Karthik Ganesan
  • Publication number: 20180135102
    Abstract: Systems and methods for performing simultaneous nucleic acid amplification and detection. The systems and methods comprise methods for managing a plurality of protocols in conjunction with directing a sensor array across each of a plurality of reaction chambers. In certain embodiments, the protocols comprise thermocycling profiles and the methods may introduce offsets and duration extensions into the thermocycling profiles to achieve more efficient detection behavior.
    Type: Application
    Filed: September 15, 2017
    Publication date: May 17, 2018
    Inventors: Thomas Catalino Gubatayao, Kalyan Handique, Karthik Ganesan, Daniel M. Drummond
  • Publication number: 20180119204
    Abstract: A microfluidic processing device includes a substrate defining a microfluidic network. The substrate is in thermal communication with a plurality of N independently controllable components and a plurality of input output contacts for connecting the substrate to an external controller. Each component has at least two terminals. Each terminal is in electrical communication with at least one contact. The number of contacts required to independently control the N components is substantially less than the total number of terminals. Upon actuation, the components typically heat a portion of the microfluidic network and/or sense a temperature thereof.
    Type: Application
    Filed: June 12, 2017
    Publication date: May 3, 2018
    Inventors: Karthik Ganesan, Kalyan Handique
  • Publication number: 20180112252
    Abstract: A microfluidic device includes an input port for inputting a particle-containing liquidic samples into the device, a retention member, and a pressure actuator. The retention member is in communication with the input port and is configured to spatially separate particles of the particle-containing liquidic sample from a first portion of the liquid of the particle containing fluidic sample. The pressure actuator recombines at least some of the separated particles with a subset of the first portion of the liquid separated from the particles. The device can also include a lysing chamber that receives the particles and liquid from the retention member. The lysing chamber thermally lyses the particles to release contents thereof.
    Type: Application
    Filed: June 2, 2017
    Publication date: April 26, 2018
    Inventors: Kalyan Handique, Gene Parunak, Aaron Kehrer, Betty Wu, Karthik Ganesan
  • Publication number: 20180097787
    Abstract: Techniques for multifactor authentication as a network service are disclosed. In some embodiments, a system, process, and/or computer program product for multifactor authentication as a network service includes monitoring a session at a firewall, applying an authentication profile based on the new session, and performing an action based on the authentication profile.
    Type: Application
    Filed: September 30, 2016
    Publication date: April 5, 2018
    Inventors: Ashwath Sreenivasa Murthy, Karthik Ganesan, Prabhakar M V B R Mangam, Shriram S. Jandhyala, Martin Walter
  • Publication number: 20180088023
    Abstract: A system and method for isolating and analyzing single cells, including: a substrate having a broad surface; a set of wells defined at the broad surface of the substrate, and a set of channels, defined by the wall, that fluidly couple each well to at least one adjacent well in the set of wells; and fluid delivery module defining an inlet and comprising a plate, removably coupled to the substrate, the plate defining a recessed region fluidly connected to the inlet and facing the broad surface of the substrate, the fluid delivery module comprising a cell capture mode.
    Type: Application
    Filed: November 16, 2017
    Publication date: March 29, 2018
    Inventors: Kalyan Handique, Austin Payne, Vishal Sharma, Kyle Gleason, Priyadarshini Gogoi, Karthik Ganesan, Brian Boniface, Will Chow
  • Publication number: 20180052708
    Abstract: An offload engine may attempt to offload, on behalf of applications, data operations to be performed on a datastream. The offload engine may intercept one or more data operations, such as may be part of a collections API, performed by an application. The data operations and the datastream may be specified and/or provided by the application and, in response, the offload engine may be configured to execute (or attempt to execute) the data operations on the datastream using an analytics accelerating co-processor rather than using a general purpose CPU core. The offload engine may determine whether or not to offload the data operations to the analytics accelerating co-processor. If the offload is unsuccessful or if the offload engine determines that the data operations are not suitable for offloading, the offload engine may then cause the data operations to be performed using general purpose CPU cores on the system.
    Type: Application
    Filed: October 6, 2016
    Publication date: February 22, 2018
    Inventors: Karthik Ganesan, Shrinivas B. Joshi, Yao-Min Chen, Luyang Wang, Ahmed Khawaja
  • Patent number: 9765389
    Abstract: Systems and methods for performing simultaneous nucleic acid amplification and detection. The systems and methods comprise methods for managing a plurality of protocols in conjunction with directing a sensor array across each of a plurality of reaction chambers. In certain embodiments, the protocols comprise thermocycling profiles and the methods may introduce offsets and duration extensions into the thermocycling profiles to achieve more efficient detection behavior.
    Type: Grant
    Filed: October 15, 2013
    Date of Patent: September 19, 2017
    Assignee: Becton, Dickinson and Company
    Inventors: Thomas Catalino Gubatayao, Kalyan Handique, Karthik Ganesan, Daniel M. Drummond
  • Patent number: 9677121
    Abstract: A microfluidic processing device includes a substrate defining a microfluidic network. The substrate is in thermal communication with a plurality of N independently controllable components and a plurality of input output contacts for connecting the substrate to an external controller. Each component has at least two terminals. Each terminal is in electrical communication with at least one contact. The number of contacts required to independently control the N components is substantially less than the total number of terminals. Upon actuation, the components typically heat a portion of the microfluidic network and/or sense a temperature thereof.
    Type: Grant
    Filed: November 21, 2014
    Date of Patent: June 13, 2017
    Assignee: HandyLab, Inc.
    Inventors: Karthik Ganesan, Kalyan Handique
  • Patent number: 9670528
    Abstract: A microfluidic device includes an input port for inputting a particle-containing liquidic samples into the device, a retention member, and a pressure actuator. The retention member is in communication with the input port and is configured to spatially separate particles of the particle-containing liquidic sample from a first portion of the liquid of the particle containing fluidic sample. The pressure actuator recombines at least some of the separated particles with a subset of the first portion of the liquid separated from the particles. The device can also include a lysing chamber that receives the particles and liquid from the retention member. The lysing chamber thermally lyses the particles to release contents thereof.
    Type: Grant
    Filed: March 24, 2014
    Date of Patent: June 6, 2017
    Assignee: HandyLab, Inc.
    Inventors: Kalyan Handique, Gene Parunak, Aaron Kehrer, Betty Wu, Karthik Ganesan
  • Patent number: 9406361
    Abstract: A memory subsystem incorporating a die-stacked DRAM (DSDRAM) is disclosed. In one embodiment, a system include a processor implemented on a silicon interposer of an integrated circuit (IC) package, a DSDRAM coupled to the processor, the DSDRAM implemented on the silicon interposer of the IC package, and a DRAM implemented separately from the IC package. The DSDRAM and the DRAM form a main memory having a contiguous address space comprising a range of physical addresses. The physical addresses of the DSDRAM occupy a first contiguous portion of the address space, while the DRAM occupies a second contiguous portion of the address space. Each physical address of the contiguous address space is augmented with a first bit that, when set, indicates that a page is stored in the DRAM and the DSDRAM.
    Type: Grant
    Filed: March 27, 2014
    Date of Patent: August 2, 2016
    Assignee: Oracle International Corporation
    Inventors: Jee Ho Ryoo, Karthik Ganesan, Yao-Min Chen
  • Patent number: 9259735
    Abstract: The present invention provides control methods, control systems, and control software for microfluidic devices that operate by moving discrete micro-droplets through a sequence of determined configurations. Such microfluidic devices are preferably constructed in a hierarchical and modular fashion which is reflected in the preferred structure of the provided methods and systems. In particular, the methods are structured into low-level device component control functions, middle-level actuator control functions, and high-level micro-droplet control functions. Advantageously, a microfluidic device may thereby be instructed to perform an intended reaction or analysis by invoking micro-droplet control function that perform intuitive tasks like measuring, mixing, heating, and so forth. The systems are preferably programmable and capable of accommodating microfluidic devices controlled by low voltages and constructed in standardized configurations.
    Type: Grant
    Filed: June 27, 2014
    Date of Patent: February 16, 2016
    Assignee: HandyLab, Inc.
    Inventors: Kalyan Handique, Karthik Ganesan, Sundaresh N. Brahmasandra
  • Publication number: 20150328638
    Abstract: This patent application describes an integrated apparatus for processing polynucleotide-containing samples, and for providing a diagnostic result thereon. The apparatus is configured to receive a microfluidic cartridge that contains reagents and a network for processing a sample. Also described are methods of using the apparatus.
    Type: Application
    Filed: May 22, 2015
    Publication date: November 19, 2015
    Inventors: Kalyan Handique, Sundaresh N. Brahmasandra, Karthik Ganesan, Betty Wu, Nikhil Phadke, Gene Parunak, Jeff Williams
  • Publication number: 20150315631
    Abstract: The present technology provides for an apparatus for detecting polynucleotides in samples, particularly from biological samples. The technology more particularly relates to microfluidic systems that carry out PCR on nucleotides of interest within microfluidic channels, and detect those nucleotides. The apparatus includes a microfluidic cartridge that is configured to accept a plurality of samples, and which can carry out PCR on each sample individually, or a group of, or all of the plurality of samples simultaneously.
    Type: Application
    Filed: July 10, 2015
    Publication date: November 5, 2015
    Inventors: Kalyan Handique, Sundaresh N. Brahmasandra, Karthik Ganesan, Jeff Williams
  • Publication number: 20150279436
    Abstract: A memory subsystem incorporating a die-stacked DRAM (DSDRAM) is disclosed. In one embodiment, a system include a processor implemented on a silicon interposer of an integrated circuit (IC) package, a DSDRAM coupled to the processor, the DSDRAM implemented on the silicon interposer of the IC package, and a DRAM implemented separately from the IC package. The DSDRAM and the DRAM form a main memory having a contiguous address space comprising a range of physical addresses. The physical addresses of the DSDRAM occupy a first contiguous portion of the address space, while the DRAM occupies a second contiguous portion of the address space. Each physical address of the contiguous address space is augmented with a first bit that, when set, indicates that a page is stored in the DRAM and the DSDRAM.
    Type: Application
    Filed: March 27, 2014
    Publication date: October 1, 2015
    Inventors: Jee Ho Ryoo, Karthik Ganesan, Yao-Min Chen
  • Patent number: 9080207
    Abstract: The present technology provides for an apparatus for detecting polynucleotides in samples, particularly from biological samples. The technology more particularly relates to microfluidic systems that carry out PCR on nucleotides of interest within microfluidic channels, and detect those nucleotides. The apparatus includes a microfluidic cartridge that is configured to accept a plurality of samples, and which can carry out PCR on each sample individually, or a group of, or all of the plurality of samples simultaneously.
    Type: Grant
    Filed: December 3, 2012
    Date of Patent: July 14, 2015
    Assignee: HandyLab, Inc.
    Inventors: Kalyan Handique, Sundaresh N Brahmasandra, Karthik Ganesan, Jeff Williams