Patents by Inventor Karthik Ramachandran
Karthik Ramachandran has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240091413Abstract: Methods for viscosupplementation in a joint or surgical site of a human or animal subject are disclosed along with unique materials for achieving such beneficial outcomes. The methods generally comprise introducing into the joint or surgical site a plurality of porous viscoelastic solid hydrogel microparticles having a size of greater than about 30 pm, and substantially free of any cells, tissue, or therapeutic compounds. Kits for viscosupplementation in a joint or surgical site of a human or animal subject are also disclosed. The kits comprise the plurality of porous viscoelastic solid hydrogel microparticles having a size of greater than about 30 pm, and substantially free of any cells, tissue, or therapeutic compounds, and instructions for administering the same.Type: ApplicationFiled: December 9, 2021Publication date: March 21, 2024Inventors: Megan E. Hamilton, Stephen Harrington, Karthik Ramachandran, Lisa Stehno-Bittel
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Publication number: 20230208847Abstract: A method is disclosed for automating creation of an account to access to a plurality of cloud based platforms, comprising receiving an intake request; determining whether the account is requested on a first cloud platform or a second cloud platform; determining whether an environment is requested; in response to a determination that an environment is requested, creating a created environment; in response to a determination that an environment is not requested, associating an existing environment with the account; in response to a determination that an environment is requested and a determination that the account is requested on the first cloud platform, creating network handlers; creating a workspace and a repository; creating vault secrets; in response to a determination that the account is requested on the first cloud platform, and tagging at least one resource associated with the account with a resource tag.Type: ApplicationFiled: March 1, 2023Publication date: June 29, 2023Applicant: Elevance Health, Inc.Inventors: Karthik Ramachandran, Jason Pichardo, Lee Graves, Val Ezike, Barry Martin, Mamadou Bah, Wesley Carlton
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Publication number: 20230081725Abstract: Systems and methods include detection, at a first application executed by a first computing system, of a change to a second object of a second application executed by a second computing system, determination of whether to identify related objects based on the change to the second object, querying, if it is determined to identify related objects based on the change to the second object, of a graph of relations between objects of the first application and objects of the second application to determine third objects of the first application which are affected by the change to the second object, and presentation of the determined third objects.Type: ApplicationFiled: September 14, 2021Publication date: March 16, 2023Inventors: Karthik RAMACHANDRAN, Michael KASTNER
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Publication number: 20230036145Abstract: A method is disclosed for automating creation of an account to access to a plurality of cloud based platforms, comprising receiving an intake request; determining whether the account is requested on a first cloud platform or a second cloud platform; determining whether an environment is requested; in response to a determination that an environment is requested, creating a created environment; in response to a determination that an environment is not requested, associating an existing environment with the account; in response to a determination that an environment is requested and a determination that the account is requested on the first cloud platform, creating network handlers; creating a workspace and a repository; creating vault secrets; in response to a determination that the account is requested on the first cloud platform, and tagging at least one resource associated with the account with a resource tag.Type: ApplicationFiled: August 1, 2022Publication date: February 2, 2023Applicant: Elevance Health, Inc.Inventors: Karthik Ramachandran, Jason Pichardo, Lee Graves, Val Ezike, Barry Martin, Mamadou Bah, Wesley Carlton
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Publication number: 20220233454Abstract: Non-alginate hydrogel microparticles for localized delivery and sustained release of therapeutic cells and/or tissues (including homogenous or heterogenous cell clusters) at a site of implantation. The microparticles comprise a 3-dimensional matrix of covalently crosslinked non-alginate polymer compounds and a therapeutically-effective amount of cells and/or tissue entrapped therein, wherein the cells have a viability of at least about 50%, and wherein the microparticle has a size of greater than about 30 pm. Compositions containing such microparticles and methods of using such microparticles for treatment are also described.Type: ApplicationFiled: June 5, 2020Publication date: July 28, 2022Inventors: Lindsey Ott, Stephen Harrington, Karthik Ramachandran, Lisa Stehno-Bittel, Megan E. Hamilton
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Patent number: 10936497Abstract: In general, embodiments of the technology relate to a method and system for storing and reading data from persistent storage. More specifically, embodiments of the technology relate to a method and system for storing data in persistent storage, where the data written to the persistent storage is not immediately accessible in the persistent storage (i.e., during the inaccessibility period). In such instances, embodiments of the technology provide a method and system to enable the storage system to service read requests for the data using a primary cache entry table (PCET) and an overflow table.Type: GrantFiled: May 14, 2019Date of Patent: March 2, 2021Assignee: EMC IP Holding Company LLCInventors: Todd Wilde, Samir Rajadnya, Karthik Ramachandran, Michael Nishimoto
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Publication number: 20190266095Abstract: In general, embodiments of the technology relate to a method and system for storing and reading data from persistent storage. More specifically, embodiments of the technology relate to a method and system for storing data in persistent storage, where the data written to the persistent storage is not immediately accessible in the persistent storage (i.e., during the inaccessibility period). In such instances, embodiments of the technology provide a method and system to enable the storage system to service read requests for the data using a primary cache entry table (PCET) and an overflow table.Type: ApplicationFiled: May 14, 2019Publication date: August 29, 2019Inventors: Todd Wilde, Samir Rajadnya, Karthik Ramachandran, Michael Nishimoto
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Patent number: 10339062Abstract: In general, embodiments of the technology relate to a method and system for storing and reading data from persistent storage. More specifically, embodiments of the technology relate to a method and system for storing data in persistent storage, where the data written to the persistent storage is not immediately accessible in the persistent storage (i.e., during the inaccessibility period). In such instances, embodiments of the technology provide a method and system to enable the storage system to service read requests for the data using a primary cache entry table (PCET) and an overflow table.Type: GrantFiled: April 28, 2017Date of Patent: July 2, 2019Assignee: EMC IP Holding Company LLCInventors: Todd Wilde, Samir Rajadnya, Karthik Ramachandran, Michael Nishimoto
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Patent number: 10331600Abstract: One or more virtual functions are exposed via a shared communication interface. Memory across said virtual functions is shared to provide a fixed number of I/O buffers shared across said virtual functions. For each of said one or more virtual functions, storing a corresponding map table configured to store a mapping data that maps a logical block address of the virtual function to a corresponding allocated one of said fixed number of I/O buffers based at least in part on a current state of a state machine.Type: GrantFiled: March 31, 2016Date of Patent: June 25, 2019Assignee: EMC IP Holding Company LLCInventors: Samir Rajadnya, Karthik Ramachandran, Todd Wilde
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Patent number: 10155928Abstract: Described herein are 3-dimensional clusters of reaggregated cells comprising cells reaggregated from at least two different cell sources, such as different cell types, different donors, and combinations thereof. Methods of making, using, and cryopreserving these 3-dimensional clusters of reaggregated cells are also described herein.Type: GrantFiled: December 28, 2016Date of Patent: December 18, 2018Assignee: The University of KansasInventors: Lisa Stehno-Bittel, Karthik Ramachandran, Sonia Rawal
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Publication number: 20180314639Abstract: In general, embodiments of the technology relate to a method and system for storing and reading data from persistent storage. More specifically, embodiments of the technology relate to a method and system for storing data in persistent storage, where the data written to the persistent storage is not immediately accessible in the persistent storage (i.e., during the inaccessibility period). In such instances, embodiments of the technology provide a method and system to enable the storage system to service read requests for the data using a primary cache entry table (PCET) and an overflow table.Type: ApplicationFiled: April 28, 2017Publication date: November 1, 2018Inventors: Todd Wilde, Samir Rajadnya, Karthik Ramachandran, Michael Nishimoto
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Patent number: 10007443Abstract: One or more virtual functions is exposed via a shared communication interface. A plurality of I/O buffers shared across said virtual functions are provided. For each of said one or more virtual functions, a corresponding submission queue comprising one or more virtual submission queue entries (SQEs) is used, wherein a memory access device is configured to: receive data pushed to the memory access device by a client host system, store the data in an allocated one of the I/O buffers, receive a submission queue entry (SQE) that invokes one of said virtual functions with respect to the data, and use a corresponding one of the plurality of logic circuits that is associated with the invoked virtual function to perform the virtual function with respect to the data as stored in the allocated I/O buffer.Type: GrantFiled: March 31, 2016Date of Patent: June 26, 2018Assignee: EMC IP Holding Company LLCInventors: Samir Rajadnya, Karthik Ramachandran, Todd Wilde
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Patent number: 10002087Abstract: A request is received via a message submission queue. The request is sent from a core associated with an external processor coupled by a communication interface. The message submission queue is associated with a memory access engine circuit configured to perform one or more memory access functions. The memory access engine circuit is used to dequeuer a next message from its corresponding message submission queue. The memory access engine circuit is used to perform a message function invoked by the message. The memory access engine circuit is used to receive a result of performing the message function. The memory access engine circuit is used to prepare and send to an external processing core that sent the message a response message determined based at least in part on the result.Type: GrantFiled: March 31, 2016Date of Patent: June 19, 2018Assignee: EMC IP Holding Company LLCInventors: Samir Rajadnya, Karthik Ramachandran, Michael Nishimoto, Richard H. Van Gaasbeck, Bruce Wong
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Patent number: 9988161Abstract: In a method of loading checked luggage on unit load devices corresponding to an aircraft having a passenger compartment, each piece of checked luggage is associated with a unique identifier. Each piece of checked luggage is weighed and its weight is associated with its corresponding unique identifier. A best possible luggage placement is calculated considering a distribution of passenger weight, thereby allowing the passengers to sit at their preferred location rather than by pre-allocation. A desired placement of the checked luggage is calculated based on the weight of each piece of checked luggage, the acceptable distribution of weight in the passenger compartment and overall fuel state over mission profile.Type: GrantFiled: June 7, 2017Date of Patent: June 5, 2018Inventors: Mohit Gupta, Aarohi Shah, Karthik Ramachandran
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Publication number: 20170349299Abstract: In a method of loading checked luggage on unit load devices corresponding to an aircraft having a passenger compartment, each piece of checked luggage is associated with a unique identifier. Each piece of checked luggage is weighed and its weight is associated with its corresponding unique identifier. A best possible luggage placement is calculated considering a distribution of passenger weight, thereby allowing the passengers to sit at their preferred location rather than by pre-allocation. A desired placement of the checked luggage is calculated based on the weight of each piece of checked luggage, the acceptable distribution of weight in the passenger compartment and overall fuel state over mission profile.Type: ApplicationFiled: June 7, 2017Publication date: December 7, 2017Inventors: Mohit Gupta, Aarohi Shah, Karthik Ramachandran
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Patent number: 9642814Abstract: Inside-out gelation process to generate hydrogel microcapsules (aka microbeads). Methods of encapsulating biological material in the microbead 3-dimensional hydrogel matrix are described herein. The process generally comprises formation of a mixture of a hydrogel precursor compound, an optional biological material, and a divalent cation. The mixture is then combined with alginate, to generate an alginate shell around droplets of the mixture, followed by gelation of the hydrogel precursor core, and removal of the temporary alginate shell to yield self-sustaining microbeads.Type: GrantFiled: June 3, 2015Date of Patent: May 9, 2017Assignee: Likarda, LLCInventors: Karthik Ramachandran, Stephen Michael Harrington
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Publication number: 20170107497Abstract: Described herein are 3-dimensional clusters of reaggregated cells comprising cells reaggregated from at least two different cell sources, such as different cell types, different donors, and combinations thereof. Methods of making, using, and cryopreserving these 3-dimensional clusters of reaggregated cells are also described herein.Type: ApplicationFiled: December 28, 2016Publication date: April 20, 2017Inventors: Lisa Stehno-Bittel, Karthik Ramachandran, Sonia Rawal
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Patent number: 9567570Abstract: Described herein are 3-dimensional clusters of reaggregated cells comprising cells reaggregated from at least two different cell sources, such as different cell types, different donors, and combinations thereof. Methods of making, using, and cryopreserving these 3-dimensional clusters of reaggregated cells are also described herein.Type: GrantFiled: October 11, 2013Date of Patent: February 14, 2017Assignee: The University of KansasInventors: Lisa Stehno-Bittel, Karthik Ramachandran, Sonia Rawal
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Publication number: 20150352056Abstract: Inside-out gelation process to generate hydrogel microcapsules (aka microbeads). Methods of encapsulating biological material in the microbead 3-dimensional hydrogel matrix are described herein. The process generally comprises formation of a mixture of a hydrogel precursor compound, an optional biological material, and a divalent cation. The mixture is then combined with alginate, to generate an alginate shell around droplets of the mixture, followed by gelation of the hydrogel precursor core, and removal of the temporary alginate shell to yield self-sustaining microbeads.Type: ApplicationFiled: June 3, 2015Publication date: December 10, 2015Inventors: Karthik Ramachandran, Stephen Michael Harrington
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Publication number: 20150259650Abstract: Described herein are 3-dimensional clusters of reaggregated cells comprising cells reaggregated from at least two different cell sources, such as different cell types, different donors, and combinations thereof. Methods of making, using, and cryopreserving these 3-dimensional clusters of reaggregated cells are also described herein.Type: ApplicationFiled: October 11, 2013Publication date: September 17, 2015Inventors: Lisa Stehno-Bittel, Karthik Ramachandran, Sonia Rawal