Abstract: Substrates and devices for culturing cells are disclosed, along with methods of using the same. The substrates and devices include top surfaces with one or more divots disposed therein. Each divot is defined by an opening in the top surface, a rounded bottom surface spaced from the opening, and an interior side-wall surface extending between the rounded bottom surface and the opening. The top surface of the substrates and devices are optionally walled to form wells containing one or more divots. The substrates and devices may be used for reaggregating cells, for example, to form small islet cell clusters and for high throughput testing methodologies.

Abstract: A population of small reaggregated islets or clusters engineered from individual islet cells and having improved characteristics as compared to native isolated islets.

Abstract: Meaningful phrases are distinguished from chance word sequences statistically, by analyzing a large number of documents and using a statistical metric such as a mutual information metric to distinguish meaningful phrases from groups of words that co-occur by chance. In some embodiments, multiple lists of candidate phrases are maintained to optimize the storage requirement of the phrase-identification algorithm. After phrase identification, a combination of words and meaningful phrases can be used to construct clusters of documents.

Abstract: A scaffold having islet cells or small islet cell clusters attached thereto in a multilayer, and a micro-mold having divots for culturing islets, wherein islet formation is influenced by the shape and dimensions of the divots are disclosed.

Abstract: Meaningful phrases are distinguished from chance word sequences statistically, by analyzing a large number of documents and using a statistical metric such as a mutual information metric to distinguish meaningful phrases from groups of words that co-occur by chance. In some embodiments, multiple lists of candidate phrases are maintained to optimize the storage requirement of the phrase-identification algorithm. After phrase identification, a combination of words and meaningful phrases can be used to construct clusters of documents.

Abstract: Substrates and devices for culturing cells are disclosed, along with methods of using the same. The substrates and devices include top surfaces with one or more divots disposed therein. Each divot is defined by an opening in the top surface, a rounded bottom surface spaced from the opening, and an interior side-wall surface extending between the rounded bottom surface and the opening. The top surface of the substrates and devices are optionally walled to form wells containing one or more divots. The substrates and devices may be used for reaggregating cells, for example, to form small islet cell clusters and for high throughput testing methodologies.

Abstract: Reliable identification of highly similar documents allows such documents to be treated as identical for purposes of document analysis. Identification of highly similar documents can be based on a composite hash value or other value for which the likelihood of two documents having the same value is high if and only if the documents have a high degree of similarity. Prior to performing content based analysis, the composite hash value for the current document is determined and compared to composite hash values of previously analyzed documents. If a match is found, the results of the analysis of the previous document can be applied to the current document. If no match is found, the current document is analyzed.

Abstract: Meaningful phrases are distinguished from chance word sequences statistically, by analyzing a large number of documents and using a statistical metric such as a mutual information metric to distinguish meaningful phrases from groups of words that co-occur by chance. In some embodiments, multiple lists of candidate phrases are maintained to optimize the storage requirement of the phrase-identification algorithm. After phrase identification, a combination of words and meaningful phrases can be used to construct clusters of documents.

Abstract: A scaffold having islet cells or small islet cell clusters attached thereto in a multilayer, and a micro-mold having divots for culturing islets, wherein islet formation is influenced by the shape and dimensions of the divots are disclosed.