Patents by Inventor Katsuaki Takahashi
Katsuaki Takahashi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230251253Abstract: An electrochemiluminescence method of detecting an analyte in a liquid sample and a corresponding analysis system. An analyte in a liquid sample is detected by first providing a receptacle containing a fluid comprising protein coated magnetic microparticles to a stirring unit. Stirring of the fluid is necessary since the density of the microparticles is usually higher than the density of the buffer fluid. Thus the microparticles tend to deposit on the bottom of the receptacle leading to an aggregation of the microparticles because of weak interactions. To obtain representative measurements a homogeneous distribution of the microparticles in the buffer fluid is necessary to ensure a constant concentration of microparticles for each analysis cycle. It is further necessary to provide disaggregation of the microparticles, which is also realized by stirring the fluid. Stirring is conducted with a rotational frequency that is adapted to the amount of fluid to be stirred.Type: ApplicationFiled: April 14, 2023Publication date: August 10, 2023Applicants: Roche Diagnostics Operations, Inc., Hitachi High-Tech CorporationInventors: Ralf Kraus, Oliver Larbolette, Friedrich Staebler, Yoshihiro Yamashita, Yukinori Sakashita, Shinya Matsuoka, Michihiro Saito, Taku Sakazume, Katsuaki Takahashi
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Patent number: 11703504Abstract: An electrochemiluminescence method of detecting an analyte in a liquid sample and a corresponding analysis system. An analyte in a liquid sample is detected by first providing a receptacle containing a fluid comprising protein coated magnetic microparticles to a stirring unit. Stirring of the fluid is necessary since the density of the microparticles is usually higher than the density of the buffer fluid. Thus the microparticles tend to deposit on the bottom of the receptacle leading to an aggregation of the microparticles because of weak interactions. To obtain representative measurements a homogeneous distribution of the microparticles in the buffer fluid is necessary to ensure a constant concentration of microparticles for each analysis cycle. It is further necessary to provide disaggregation of the microparticles, which is also realized by stirring the fluid. Stirring is conducted with a rotational frequency that is adapted to the amount of fluid to be stirred.Type: GrantFiled: September 5, 2019Date of Patent: July 18, 2023Assignees: ROCHE DIAGNOSTICS OPERATIONS, INC., HITACHI HIGH-TECH CORPORATIONInventors: Ralf Kraus, Oliver Larbolette, Friedrich Staebler, Yoshihiro Yamashita, Yukinori Sakashita, Shinya Matsuoka, Michihiro Saito, Taku Sakazume, Katsuaki Takahashi
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Publication number: 20200003768Abstract: An electrochemiluminescence method of detecting an analyte in a liquid sample and a corresponding analysis system. An analyte in a liquid sample is detected by first providing a receptacle containing a fluid comprising protein coated magnetic microparticles to a stirring unit. Stirring of the fluid is necessary since the density of the microparticles is usually higher than the density of the buffer fluid. Thus the microparticles tend to deposit on the bottom of the receptacle leading to an aggregation of the microparticles because of weak interactions. To obtain representative measurements a homogeneous distribution of the microparticles in the buffer fluid is necessary to ensure a constant concentration of microparticles for each analysis cycle. It is further necessary to provide disaggregation of the microparticles, which is also realized by stirring the fluid. Stirring is conducted with a rotational frequency that is adapted to the amount of fluid to be stirred.Type: ApplicationFiled: September 5, 2019Publication date: January 2, 2020Applicants: Roche Diagnostics Operations, Inc., Hitachi High-Technologies CorporationInventors: Ralf Kraus, Oliver Larbolette, Friedrich Staebler, Yoshihiro y Yamashita, Yukinori Sakashita, Shinya Matsuoka, Michihiro Saito, Taku Sakazume, Katsuaki Takahashi
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Patent number: 10422797Abstract: An electrochemiluminescence method of detecting an analyte in a liquid sample and a corresponding analysis system. An analyte in a liquid sample is detected by first providing a receptacle containing a fluid comprising protein coated magnetic microparticles to a stirring unit. Stirring of the fluid is necessary since the density of the microparticles is usually higher than the density of the buffer fluid. Thus the microparticles tend to deposit on the bottom of the receptacle leading to an aggregation of the microparticles because of weak interactions. To obtain representative measurements a homogeneous distribution of the microparticles in the buffer fluid is necessary to ensure a constant concentration of microparticles for each analysis cycle. It is further necessary to provide disaggregation of the microparticles, which is also realized by stirring the fluid. Stirring is conducted with a rotational frequency that is adapted to the amount of fluid to be stirred.Type: GrantFiled: December 14, 2015Date of Patent: September 24, 2019Assignees: ROCHE DIAGNOSTICS OPERATIONS, INC., HITACHI HIGH-TECHNOLOGIES CORPORATIONInventors: Ralf Kraus, Oliver Larbolette, Friedrich Staebler, Yoshihiro Yamashita, Yukinori Sakashita, Shinya Matsuoka, Michihiro Saito, Taku Sakazume, Katsuaki Takahashi
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Patent number: 10110171Abstract: An output signal can be free of any noise component generated from an amplifier disposed in a path, without degradation of the S/N ratio of the output signal. An amplifier includes: a first amplifier that is connected to an input node and generates a first intermediate signal; a feedback resistor that enables feedback of the first intermediate signal to the input node; an attenuator that receives the first intermediate signal and generates a second intermediate signal; a second amplifier that is connected to the input node and generates a third intermediate signal; a third amplifier that is connected to the input node and generates a fourth intermediate signal; and an adder that generates an output signal, using the second intermediate signal, the third intermediate signal, and the fourth intermediate signal.Type: GrantFiled: November 19, 2015Date of Patent: October 23, 2018Assignee: SONY CORPORATIONInventors: Katsuaki Takahashi, Hideyuki Takano, Naoto Yoshikawa
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Publication number: 20180088187Abstract: A magnetic sensor includes: a first Hall element that measures magnetic flux density; a second Hall element that measures the magnetic flux density; and a base member where the first Hall element is mounted on one surface, and the second Hall element is mounted on the other surface, in which the first Hall element and the second Hall element are disposed such that a measurement surface of the first Hall element and a measurement surface of the second Hall element are parallel to each other, and are symmetrical to the base member.Type: ApplicationFiled: September 14, 2017Publication date: March 29, 2018Applicant: AISIN SEIKI KABUSHIKI KAISHAInventor: Katsuaki TAKAHASHI
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Patent number: 9915672Abstract: According to an embodiment of the disclosure, the analyzer includes a reagent driving disk that accommodates a reagent configured for analysis and that transports the reagent to a desired position, and a fixed disk that has a reagent stand-by position in which to make a reagent container containing the reagent, temporarily stand by, and a magnetic particles stirring position for stirring magnetic particles. A portion of the reagent stand-by position is constituted by a loading system. A reagent container moving unit moves reagent containers containing the reagent, between the reagent driving unit and the fixed disk, according to analytical request status. Providing in a part of the fixed disk the loading system constructed so that reagent containers containing the reagent can be mounted therein during operation enables changing of reagent containers, irrespective of an operational status of the reagent driving disk, and the system to having cold-storage functionality.Type: GrantFiled: January 13, 2016Date of Patent: March 13, 2018Assignees: Roche Diagnostics Operations, Inc., Hitachi High-Technologies CorporationInventors: Reinhold Kraemer, Susumu Sakairi, Stephan Sattler, Katsuaki Takahashi
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Publication number: 20170338774Abstract: An output signal can be free of any noise component generated from an amplifier disposed in a path, without degradation of the S/N ratio of the output signal. An amplifier includes: a first amplifier that is connected to an input node and generates a first intermediate signal; a feedback resistor that enables feedback of the first intermediate signal to the input node; an attenuator that receives the first intermediate signal and generates a second intermediate signal; a second amplifier that is connected to the input node and generates a third intermediate signal; a third amplifier that is connected to the input node and generates a fourth intermediate signal; and an adder that generates an output signal, using the second intermediate signal, the third intermediate signal, and the fourth intermediate signal.Type: ApplicationFiled: November 19, 2015Publication date: November 23, 2017Inventors: KATSUAKI TAKAHASHI, HIDEYUKI TAKANO, NAOTO YOSHIKAWA
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Patent number: 9664675Abstract: Stepped portions of a flow channel are reduced by completely fixing the channel that extends to the measuring unit, and reducing connections in the channel, thereby to suppress a disturbance in the flow of the liquid suctioned into the measuring unit. A means is provided so that the reaction solution and reagent suctioned will move towards the channel through which the liquids are suctioned.Type: GrantFiled: December 7, 2015Date of Patent: May 30, 2017Assignee: Hitachi High-Technologies CorporationInventors: Susumu Sakairi, Taku Sakazume, Katsuaki Takahashi
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Patent number: 9543909Abstract: An amplifier includes a variable shunt circuit including a first transistor group and a second transistor group. The first transistor group includes at least one transistor including a first terminal connected directly or indirectly to a voltage-current conversion circuit, a second terminal connected directly or indirectly to a load, and a third terminal connected directly or indirectly to a control circuit. The second transistor group includes at least one transistor including a first terminal connected directly or indirectly to the voltage-current conversion circuit, a second terminal connected directly or indirectly to a power source or a ground, and a third terminal connected directly or indirectly to the control circuit. The amplifier is configured to amplify the input signal under exclusive control from the control circuit on a pair of the at least one transistor of the first transistor group and the at least one transistor of the second transistor group.Type: GrantFiled: February 27, 2015Date of Patent: January 10, 2017Assignee: Sony CorporationInventor: Katsuaki Takahashi
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Patent number: 9442129Abstract: An automatic analyzer cleans dispensing nozzles that dispense a sample or reagent using a rinse tank. The rinse tank includes first and second rinse liquid discharge ports arranged along the bottom and top of the rinse tank, respectively. The first rinse liquid discharge ports face the top of the rinse tank. The second rinse liquid discharge ports supply rinse liquid to flow to an exterior of the dispensing nozzles when aligned therewith. Each dispensing nozzle is rinsed by moving from a first position aligned with one of the first rinse liquid discharge ports to a second position aligned with one of the second rinse liquid discharge ports.Type: GrantFiled: January 26, 2012Date of Patent: September 13, 2016Assignee: Hitachi High-Technologies CorporationInventors: Yukinori Sakashita, Katsuaki Takahashi, Tomoyuki Nemoto
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Patent number: 9360492Abstract: The automatic analyzer includes: a disk having a plurality of holding sections for holding a plurality of containers on the circumference of the disk or on a closed loop that rotationally moves, the disk adapted to move the plurality of containers; a reagent dispensing mechanism for dispensing a reagent into the container on the disk; and a sample dispensing mechanism for dispensing a sample into the container on the disk. The automatic analyzer also includes a container transfer mechanism for mounting the container in the holding sections on the disk. The container transfer mechanism is driven in such a manner that the container can be mounted in the plurality of holding sections on the disk.Type: GrantFiled: May 18, 2011Date of Patent: June 7, 2016Assignee: Hitachi High-Technologies CorporationInventors: Katsuaki Takahashi, Taku Sakazume, Yukinori Sakashita
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Publication number: 20160124008Abstract: According to an embodiment of the disclosure, the analyzer includes a reagent driving disk that accommodates a reagent configured for analysis and that transports the reagent to a desired position, and a fixed disk that has a reagent stand-by position in which to make a reagent container containing the reagent, temporarily stand by, and a magnetic particles stirring position for stirring magnetic particles. A portion of the reagent stand-by position is constituted by a loading system. A reagent container moving unit moves reagent containers containing the reagent, between the reagent driving unit and the fixed disk, according to analytical request status. Providing in a part of the fixed disk the loading system constructed so that reagent containers containing the reagent can be mounted therein during operation enables changing of reagent containers, irrespective of an operational status of the reagent driving disk, and the system to having cold-storage functionality.Type: ApplicationFiled: January 13, 2016Publication date: May 5, 2016Inventors: Reinhold Kraemer, Susumu Sakairi, Stephan Sattler, Katsuaki Takahashi
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Publication number: 20160084827Abstract: Stepped portions of a flow channel are reduced by completely fixing the channel that extends to the measuring unit, and reducing connections in the channel, thereby to suppress a disturbance in the flow of the liquid suctioned into the measuring unit. A means is provided so that the reaction solution and reagent suctioned will move towards the channel through which the liquids are suctioned.Type: ApplicationFiled: December 7, 2015Publication date: March 24, 2016Inventors: Susumu SAKAIRI, Taku SAKAZUME, Katsuaki TAKAHASHI
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Patent number: 9274133Abstract: According to an embodiment of the disclosure, the analyzer includes a reagent driving disk that accommodates a reagent configured for analysis and that transports the reagent to a desired position, and a fixed disk that has a reagent stand-by position in which to make a reagent container containing the reagent, temporarily stand by, and a magnetic particles stirring position for stirring magnetic particles. A portion of the reagent stand-by position is constituted by a loading system. A reagent container moving unit moves reagent containers containing the reagent, between the reagent driving unit and the fixed disk, according to analytical request status. Providing in a part of the fixed disk the loading system constructed so that reagent containers containing the reagent can be mounted therein during operation enables changing of reagent containers, irrespective of an operational status of the reagent driving disk, and the system to having cold-storage functionality.Type: GrantFiled: January 27, 2012Date of Patent: March 1, 2016Assignees: Roche Diagnostics Operations, Inc., Hitachi High-Technologies CorporationInventors: Reinhold Kraemer, Susumu Sakairi, Stephan Sattler, Katsuaki Takahashi
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Patent number: 9255937Abstract: Provided is an automatic analyzer that includes a suction nozzle, a detection container, and a detector. The suction nozzle suctions a sample and a solution used for the detection of the sample. The suctioned sample and the solution are supplied to the detection container. The detector detects a signal from the sample. In addition, a vessel for the sample and a container for the solution are disposed below the detection container.Type: GrantFiled: July 20, 2011Date of Patent: February 9, 2016Assignee: HITACHI HIGH TECHNOLOGIES CORPORATIONInventors: Yukinori Sakashita, Katsuaki Takahashi, Yoshihiro Yamashita, Taku Sakazume
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Patent number: 9244088Abstract: Stepped portions of a flow channel are reduced by completely fixing the channel that extends to the measuring unit, and reducing connections in the channel, thereby to suppress a disturbance in the flow of the liquid suctioned into the measuring unit. A means is provided so that the reaction solution and reagent suctioned will move towards the channel through which the liquids are suctioned.Type: GrantFiled: May 30, 2014Date of Patent: January 26, 2016Assignee: HITACHI HIGH-TECHNOLOGIES CORPORATIONInventors: Susumu Sakairi, Taku Sakazume, Katsuaki Takahashi
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Publication number: 20150354564Abstract: A guide slot having an elongated-hole shape is formed in a capacity adjustment member, so that displacement of the capacity adjustment member is regulated, by a guide pin inserted into the guide slot, to a longitudinal direction of the guide slot. Two spaces separated by the guide pin into one side and the other side in the longitudinal direction of the guide slot are formed inside the guide slot, and a communicating passage is provided so as to communicate the spaces with each other.Type: ApplicationFiled: June 5, 2015Publication date: December 10, 2015Inventors: Katsuaki TAKAHASHI, Kazuhiro YOKOTA, Nobuyuki MURAKAMI, Tomoyuki KITTAKA, Hisashi ONO, Yuki NISHIDA
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Patent number: 9184718Abstract: The present technology relates to a gain control circuit, a communication device, an electronic appliance, and a gain control method which aim to provide a technology capable of suppressing intermodulation distortion. The gain control circuit includes a first amplifier for amplifying an input signal, and a signal determination unit for determining an input signal to be input to the first amplifier, and controlling an amplification factor of the first amplifier based on the determination result. The communication device includes a first amplifier for amplifying a received signal, a receiving unit for performing a receiving process based on a signal output from the first amplifier, and a signal determination unit for determining a received signal to be input to the first amplifier, and controlling the amplification factor of the first amplifier based on the determination result.Type: GrantFiled: March 7, 2012Date of Patent: November 10, 2015Assignee: Sony CorporationInventors: Katsuaki Takahashi, Naoto Yoshikawa
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Publication number: 20150263691Abstract: An amplifier includes a variable shunt circuit including a first transistor group and a second transistor group. The first transistor group includes at least one transistor including a first terminal connected directly or indirectly to a voltage-current conversion circuit, a second terminal connected directly or indirectly to a load, and a third terminal connected directly or indirectly to a control circuit. The second transistor group includes at least one transistor including a first terminal connected directly or indirectly to the voltage-current conversion circuit, a second terminal connected directly or indirectly to a power source or a ground, and a third terminal connected directly or indirectly to the control circuit. The amplifier is configured to amplify the input signal under exclusive control from the control circuit on a pair of the at least one transistor of the first transistor group and the at least one transistor of the second transistor group.Type: ApplicationFiled: February 27, 2015Publication date: September 17, 2015Inventor: Katsuaki Takahashi