Patents by Inventor Katsushige Ikai

Katsushige Ikai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100137228
    Abstract: Medicinal compositions for treating, ameliorating or preventing diseases with sensitivity to 3,6-anhydrogalactopyranose represented by formula (1): foods, drinks, cosmetics, etc. containing as the active ingredient at least one member selected from the group consisting of the above-mentioned compound, its aldehyde, its hydrate and 2-O-methylated derivatives thereof and soluble sugar compounds containing the above compound. This compound also shows, for example, an apoptosis-inducing activity, a carcinostatic activity and inhibitory activities on the production of active oxygen, lipid peroxide radicals and NO, which makes it useful also as the active ingredient of antioxidants and preservatives.
    Type: Application
    Filed: August 11, 2008
    Publication date: June 3, 2010
    Applicant: TAKARA BIO INC.
    Inventors: Tatsuji ENOKI, Hiroaki SAGAWA, Takanari TOMINAGA, Eiji NISHIYAMA, Nobuto KOYAMA, Takeshi SAKAI, Fu-Gong YU, Katsushige IKAI, Ikunoshin KATO
  • Publication number: 20100048491
    Abstract: Medicinal compositions for treating, ameliorating or preventing diseases with sensitivity to 3,6-anhydrogalactopyranose represented by formula (1): foods, drinks, cosmetics, etc. containing as the active ingredient at least one member selected from the group consisting of the above-mentioned compound, its aldehyde, its hydrate and 2-O-methylated derivatives thereof and soluble sugar compounds containing the above compound. This compound also shows, for example, an apoptosis-inducing activity, a carcinostatic activity and inhibitory activities on the production of active oxygen, lipid peroxide radicals and NO, which makes it useful also as the active ingredient of antioxidants and preservatives.
    Type: Application
    Filed: August 11, 2008
    Publication date: February 25, 2010
    Applicant: TAKARA BIO INC.
    Inventors: Tatsuji ENOKI, Hiroaki SAGAWA, Takanari TOMINAGA, Eiji NISHIYAMA, Nobuto KOYAMA, Takeshi SAKAI, Fu-Gong YU, Katsushige IKAI, Ikunoshin KATO
  • Publication number: 20090099101
    Abstract: Medicinal compositions for treating, ameliorating or preventing diseases with sensitivity to 3,6-anhydrogalactopyranose represented by formula (1): foods, drinks, cosmetics, etc. containing as the active ingredient at least one member selected from the group consisting of the above-mentioned compound, its aldehyde, its hydrate and 2-O-methylated derivatives thereof and soluble sugar compounds containing the above compound. This compound also shows, for example, an apoptosis-inducing activity, a carcinostatic activity and inhibitory activities on the production of active oxygen, lipid peroxide radicals and NO, which makes it useful also as the active ingredient of antioxidants and preservatives.
    Type: Application
    Filed: August 11, 2008
    Publication date: April 16, 2009
    Applicant: Takara Shuzo Co., Ltd.
    Inventors: Tatsuji Enoki, Hiroaki Sagawa, Takanari Tominaga, Eiji Nishiyama, Nobuto Koyama, Takeshi Sakai, Fu-Gong Yu, Katsushige Ikai, Ikunoshin Kato
  • Patent number: 7422750
    Abstract: Food or beverage where fucoidan which is derived from a fucoidan-containing substance is contained therein, added thereto and/or diluted therein. Food or beverage where fucoidan which is derived from a fucoidan-containing substance and where algins are reduced or eliminated, is contained therein. Apoptosis-inducing food or beverage where an effective amount of fucoidan having an apoptosis-inducing ability is contained therein.
    Type: Grant
    Filed: April 8, 2003
    Date of Patent: September 9, 2008
    Assignee: Takara Bio Inc.
    Inventors: Yoshihisa Umeda, Hiroshi Kihara, Katsushige Ikai, Ikunoshin Kato
  • Patent number: 7417031
    Abstract: Medicinal compositions for treating, ameliorating or preventing diseases with sensitivity to 3,6-anhydrogalactopyranose represented by formula (1): foods, drinks, cosmetics, etc. containing as the active ingredient at least one member selected from the group consisting of the above-mentioned compound, its aldehyde, its hydrate and 2-O-methylated derivatives thereof and soluble sugar compounds containing the above compound. This compound also shows, for example, an apoptosis-inducing activity, a carcinostatic activity and inhibitory activities on the production of active oxygen, lipid peroxide radicals and NO, which makes it useful also as the active ingredient of antioxidants and preservatives.
    Type: Grant
    Filed: January 13, 2005
    Date of Patent: August 26, 2008
    Assignee: Takara Bio Inc.
    Inventors: Tatsui Enoki, Hiroaki Sagawa, Takanari Tominaga, Eiji Nishiyama, Nobuto Koyama, Takeshi Sakai, Fu-Gong Yu, Katsushige Ikai, Ikunoshin Kato
  • Patent number: 7125984
    Abstract: Three enzymes degrading sulfated glucuronofucan; processes for producing these enzymes; activators for these enzymes; glucuronofucan sulfate and degradation products thereof; and a novel microorganism.
    Type: Grant
    Filed: April 19, 2001
    Date of Patent: October 24, 2006
    Assignee: Takara Bio Inc.
    Inventors: Takeshi Sakai, Kumiko Ishizuka, Kaoru Kojima, Kazuo Shimanaka, Katsushige Ikai, Ikunoshin Kato
  • Publication number: 20060183715
    Abstract: An enzyme which decomposes a sulfated fucoglucuronomannan and is useful in the field of glycotechnology; a process for producing the enzyme; a fucoidan fraction reduced in the number of the kinds of molecules and useful as a reagent in glycotechnology; a sulfated fucoglucuronomannan oligosaccharide; and processes for producing the fraction and oligosaccharide.
    Type: Application
    Filed: December 28, 2005
    Publication date: August 17, 2006
    Applicant: TAKARA BIO INC.
    Inventors: Takeshi Sakai, Hitomi Kimura, Katsushige Ikai, Ikunoshin Kato
  • Publication number: 20060166335
    Abstract: Three enzymes degrading sulfated glucuronofucan; processes for producing these enzymes; activators for these enzymes; glucuronofucan sulfate and degradation products thereof; and a novel microorganism.
    Type: Application
    Filed: March 14, 2006
    Publication date: July 27, 2006
    Applicant: TAKARA BIO INC.
    Inventors: Takeshi Sakai, Kumiko Ishizuka, Kaoru Kojima, Kazuo Shimanaka, Katsushige Ikai, Ikunoshin Kato
  • Patent number: 7041656
    Abstract: An enzyme which decomposes a sulfated fucoglucuronomannan and is useful in the field of glycotechnology; a process for producing the enzyme; a fucoidan fraction reduced in the number of the kinds of molecules and useful as a reagent in glycotechnology; a sulfated fucoglucuronomannan oligosaccharide; and processes for producing the fraction and oligosaccharide.
    Type: Grant
    Filed: April 18, 2002
    Date of Patent: May 9, 2006
    Assignee: Takara Bio Inc.
    Inventors: Takeshi Sakai, Hitomi Kimura, Katsushige Ikai, Ikunoshin Kato
  • Publication number: 20050255564
    Abstract: An enzyme capable of degrading sulfated fucan originating in a brown alga of Fucales which is useful in sugar chain engineering; a process for producing this enzyme; an oligosaccharide obtained by treating sulfated fucan with the enzyme; and production thereof.
    Type: Application
    Filed: January 17, 2003
    Publication date: November 17, 2005
    Applicant: TAKARA BIO INC
    Inventors: Takeshi Sakai, Hitomi Amarume, Katsushige Ikai, Ikunoshin Kato
  • Publication number: 20050202064
    Abstract: A product obtained by heating at least one substance selected from the following (a), (b) and (c). (a) uronic acid or uronic acid derivative; (b) a saccharide compound containing uronic acid or a saccharide compound containing uronic acid derivative; and (c) a substance containing a saccharide compound containing uronic acid or a substance containing a saccharide compound containing uronic acid derivative; and food, beverage or a pharmaceutical agent which is characterized in containing the above-mentioned heat-treated product.
    Type: Application
    Filed: April 26, 2005
    Publication date: September 15, 2005
    Inventors: Nobuto Koyama, Hiroaki Sagawa, Eiji Kobayashi, Tatsuji Enoki, Hua-Kang Wu, Eiji Nishiyama, Suzu Deguchi, Katsushige Ikai, Hiromu Ohnogi, Motoko Ueda, Akihiro Kondo, Ikunoshin Kato
  • Patent number: 6927289
    Abstract: A smaller molecule obtainable by allowing a sulfated fucan-digesting enzyme which digests a novel sulfated polysaccharide derived from an alga belonging to Laminariales to act on a sulfated fucan, and a method for producing the same.
    Type: Grant
    Filed: October 28, 2003
    Date of Patent: August 9, 2005
    Assignee: Takara Bio Inc.
    Inventors: Takeshi Sakai, Hitomi Amarume, Takashi Kawai, Kaoru Kojima, Kazuo Shimanaka, Katsushige Ikai, Ikunoshin Kato
  • Patent number: 6911432
    Abstract: Medicinal compositions for treating, ameliorating or preventing diseases with sensitivity to 3,6-anhydrogalactopyranose are represented by formula (I): These compositions include foods, drinks, cosmetics, etc. containing as the active ingredient at least one such compound, its aldehyde, its hydrate and 2-O-methylated derivatives thereof and soluble sugar compounds containing the above compound. These compounds show an apoptosis-inducing activity, carcinostatic activity and inhibitory activities on the production of active oxygen, lipid peroxide radicals and NO, which makes them useful also as the active ingredient of antioxidants and preservatives.
    Type: Grant
    Filed: August 27, 2002
    Date of Patent: June 28, 2005
    Inventors: Tatsuji Enoki, Hiroaki Sagawa, Takanari Tominaga, Eiji Nishiyama, Nobuto Koyama, Takeshi Sakai, Fu-Gong Yu, Katsushige Ikai, Ikunoshin Kato
  • Publication number: 20050119191
    Abstract: Medicinal compositions for treating, ameliorating or preventing diseases with sensitivity to 3,6-anhydrogalactopyranose represented by formula (1): foods, drinks, cosmetics, etc. containing as the active ingredient at least one member selected from the group consisting of the above-mentioned compound, its aldehyde, its hydrate and 2-O-methylated derivatives thereof and soluble sugar compounds containing the above compound. This compound also shows, for example, an apoptosis-inducing activity, a carcinostatic activity and inhibitory activities on the production of active oxygen, lipid peroxide radicals and NO, which makes it useful also as the active ingredient of antioxidants and preservatives.
    Type: Application
    Filed: January 13, 2005
    Publication date: June 2, 2005
    Applicant: Takara Shuzo Co., Ltd.
    Inventors: Tatsui Enoki, Hiroaki Sagawa, Takanari Tominaga, Eiji Nishiyama, Nobuto Koyama, Takeshi Sakai, Fu-Gong Yu, Katsushige Ikai, Ikunoshin Kato
  • Publication number: 20050090456
    Abstract: An enzyme which decomposes a sulfated fucoglucuronomannan and is useful in the field of glycotechnology; a process for producing the enzyme; a fucoidan fraction reduced in the number of the kinds of molecules and useful as a reagent in glycotechnology; a sulfated fucoglucuronomannan oligosaccharide; and processes for producing the fraction and oligosaccharide.
    Type: Application
    Filed: April 18, 2002
    Publication date: April 28, 2005
    Inventors: Takeshi Sakai, Hitomi Kimura, Katsushige Ikai, Ikunoshin Kato
  • Publication number: 20050049221
    Abstract: Food or beverage where fucoidan which is derived from a fucoidan-containing substance is contained therein, added thereto and/or diluted therein. Food or beverage where fucoidan which is derived from a fucoidan-containing substance and where algins are reduced or eliminated is contained therein. Apoptosis-inducing food or beverage where an effective amount of fucoidan having an apoptosis-inducing ability is contained therein.
    Type: Application
    Filed: April 8, 2003
    Publication date: March 3, 2005
    Inventors: Yoshihisa Umeda, Hiroshi Kihara, Katsushige Ikai, Ikunoshin Kato
  • Patent number: 6809091
    Abstract: A method for the manufacture of a substance having an apoptosis-inducing ability characterized in including a step of subjecting at least one compound selected from the following (a), (b), (c) and (d) [excluding uronic acid and/or uronic acid derivatives; and compounds which contain uronic acid and/or uronic acid derivatives] to a heating treatment: (a) pentose; (b) pentose derivatives; (c) compounds containing pentose; (d) compounds containing pentose derivatives.
    Type: Grant
    Filed: June 28, 2000
    Date of Patent: October 26, 2004
    Assignee: Takara Bio Inc.
    Inventors: Yoko Tatsumi, Hiroaki Sagawa, Hiromu Ohnogi, Eiji Kobayashi, Hua-Kang Wu, Nobuto Koyama, Katsushige Ikai, Ikunoshin Kato
  • Patent number: 6803367
    Abstract: A substance for inducing apoptosis represented by specific formulae. A pharmaceutical composition which can be used for an anticancer agent containing said substance.
    Type: Grant
    Filed: October 1, 2002
    Date of Patent: October 12, 2004
    Assignee: Takara Shuzo Co., Ltd.
    Inventors: Tatsuji Enoki, Nobuto Koyama, Katsushige Ikai, Ikunoshin Kato
  • Publication number: 20040146995
    Abstract: A smaller molecule obtainable by allowing a sulfated fucan-digesting enzyme which digests a novel sulfated polysaccharide derived from an alga belonging to Laminariales to act on a sulfated fucan, and a method for producing the same.
    Type: Application
    Filed: October 28, 2003
    Publication date: July 29, 2004
    Applicant: TAKARA BIO INC.
    Inventors: Takeshi Sakai, Hitomi Amarume, Takashi Kawai, Kaoru Kojima, Kazuo Shimanaka, Katsushige Ikai, Ikunoshin Kato
  • Patent number: 6720419
    Abstract: A smaller molecule obtainable by allowing a sulfated fucan-digesting enzyme which digests a novel sulfated polysaccharide derived from an alga belonging to Laminariales to act on a sulfated fucan, and a method for producing the same.
    Type: Grant
    Filed: October 24, 2002
    Date of Patent: April 13, 2004
    Assignee: Takara Bio Inc.
    Inventors: Takeshi Sakai, Hitomi Amarume, Takashi Kawai, Kaoru Kojima, Kazuo Shimanaka, Katsushige Ikai, Ikunoshin Kato