Patents by Inventor Katsushige Ikai
Katsushige Ikai has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20100137228Abstract: Medicinal compositions for treating, ameliorating or preventing diseases with sensitivity to 3,6-anhydrogalactopyranose represented by formula (1): foods, drinks, cosmetics, etc. containing as the active ingredient at least one member selected from the group consisting of the above-mentioned compound, its aldehyde, its hydrate and 2-O-methylated derivatives thereof and soluble sugar compounds containing the above compound. This compound also shows, for example, an apoptosis-inducing activity, a carcinostatic activity and inhibitory activities on the production of active oxygen, lipid peroxide radicals and NO, which makes it useful also as the active ingredient of antioxidants and preservatives.Type: ApplicationFiled: August 11, 2008Publication date: June 3, 2010Applicant: TAKARA BIO INC.Inventors: Tatsuji ENOKI, Hiroaki SAGAWA, Takanari TOMINAGA, Eiji NISHIYAMA, Nobuto KOYAMA, Takeshi SAKAI, Fu-Gong YU, Katsushige IKAI, Ikunoshin KATO
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Publication number: 20100048491Abstract: Medicinal compositions for treating, ameliorating or preventing diseases with sensitivity to 3,6-anhydrogalactopyranose represented by formula (1): foods, drinks, cosmetics, etc. containing as the active ingredient at least one member selected from the group consisting of the above-mentioned compound, its aldehyde, its hydrate and 2-O-methylated derivatives thereof and soluble sugar compounds containing the above compound. This compound also shows, for example, an apoptosis-inducing activity, a carcinostatic activity and inhibitory activities on the production of active oxygen, lipid peroxide radicals and NO, which makes it useful also as the active ingredient of antioxidants and preservatives.Type: ApplicationFiled: August 11, 2008Publication date: February 25, 2010Applicant: TAKARA BIO INC.Inventors: Tatsuji ENOKI, Hiroaki SAGAWA, Takanari TOMINAGA, Eiji NISHIYAMA, Nobuto KOYAMA, Takeshi SAKAI, Fu-Gong YU, Katsushige IKAI, Ikunoshin KATO
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Publication number: 20090099101Abstract: Medicinal compositions for treating, ameliorating or preventing diseases with sensitivity to 3,6-anhydrogalactopyranose represented by formula (1): foods, drinks, cosmetics, etc. containing as the active ingredient at least one member selected from the group consisting of the above-mentioned compound, its aldehyde, its hydrate and 2-O-methylated derivatives thereof and soluble sugar compounds containing the above compound. This compound also shows, for example, an apoptosis-inducing activity, a carcinostatic activity and inhibitory activities on the production of active oxygen, lipid peroxide radicals and NO, which makes it useful also as the active ingredient of antioxidants and preservatives.Type: ApplicationFiled: August 11, 2008Publication date: April 16, 2009Applicant: Takara Shuzo Co., Ltd.Inventors: Tatsuji Enoki, Hiroaki Sagawa, Takanari Tominaga, Eiji Nishiyama, Nobuto Koyama, Takeshi Sakai, Fu-Gong Yu, Katsushige Ikai, Ikunoshin Kato
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Patent number: 7422750Abstract: Food or beverage where fucoidan which is derived from a fucoidan-containing substance is contained therein, added thereto and/or diluted therein. Food or beverage where fucoidan which is derived from a fucoidan-containing substance and where algins are reduced or eliminated, is contained therein. Apoptosis-inducing food or beverage where an effective amount of fucoidan having an apoptosis-inducing ability is contained therein.Type: GrantFiled: April 8, 2003Date of Patent: September 9, 2008Assignee: Takara Bio Inc.Inventors: Yoshihisa Umeda, Hiroshi Kihara, Katsushige Ikai, Ikunoshin Kato
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Patent number: 7417031Abstract: Medicinal compositions for treating, ameliorating or preventing diseases with sensitivity to 3,6-anhydrogalactopyranose represented by formula (1): foods, drinks, cosmetics, etc. containing as the active ingredient at least one member selected from the group consisting of the above-mentioned compound, its aldehyde, its hydrate and 2-O-methylated derivatives thereof and soluble sugar compounds containing the above compound. This compound also shows, for example, an apoptosis-inducing activity, a carcinostatic activity and inhibitory activities on the production of active oxygen, lipid peroxide radicals and NO, which makes it useful also as the active ingredient of antioxidants and preservatives.Type: GrantFiled: January 13, 2005Date of Patent: August 26, 2008Assignee: Takara Bio Inc.Inventors: Tatsui Enoki, Hiroaki Sagawa, Takanari Tominaga, Eiji Nishiyama, Nobuto Koyama, Takeshi Sakai, Fu-Gong Yu, Katsushige Ikai, Ikunoshin Kato
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Patent number: 7125984Abstract: Three enzymes degrading sulfated glucuronofucan; processes for producing these enzymes; activators for these enzymes; glucuronofucan sulfate and degradation products thereof; and a novel microorganism.Type: GrantFiled: April 19, 2001Date of Patent: October 24, 2006Assignee: Takara Bio Inc.Inventors: Takeshi Sakai, Kumiko Ishizuka, Kaoru Kojima, Kazuo Shimanaka, Katsushige Ikai, Ikunoshin Kato
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Publication number: 20060183715Abstract: An enzyme which decomposes a sulfated fucoglucuronomannan and is useful in the field of glycotechnology; a process for producing the enzyme; a fucoidan fraction reduced in the number of the kinds of molecules and useful as a reagent in glycotechnology; a sulfated fucoglucuronomannan oligosaccharide; and processes for producing the fraction and oligosaccharide.Type: ApplicationFiled: December 28, 2005Publication date: August 17, 2006Applicant: TAKARA BIO INC.Inventors: Takeshi Sakai, Hitomi Kimura, Katsushige Ikai, Ikunoshin Kato
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Publication number: 20060166335Abstract: Three enzymes degrading sulfated glucuronofucan; processes for producing these enzymes; activators for these enzymes; glucuronofucan sulfate and degradation products thereof; and a novel microorganism.Type: ApplicationFiled: March 14, 2006Publication date: July 27, 2006Applicant: TAKARA BIO INC.Inventors: Takeshi Sakai, Kumiko Ishizuka, Kaoru Kojima, Kazuo Shimanaka, Katsushige Ikai, Ikunoshin Kato
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Patent number: 7041656Abstract: An enzyme which decomposes a sulfated fucoglucuronomannan and is useful in the field of glycotechnology; a process for producing the enzyme; a fucoidan fraction reduced in the number of the kinds of molecules and useful as a reagent in glycotechnology; a sulfated fucoglucuronomannan oligosaccharide; and processes for producing the fraction and oligosaccharide.Type: GrantFiled: April 18, 2002Date of Patent: May 9, 2006Assignee: Takara Bio Inc.Inventors: Takeshi Sakai, Hitomi Kimura, Katsushige Ikai, Ikunoshin Kato
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Publication number: 20050255564Abstract: An enzyme capable of degrading sulfated fucan originating in a brown alga of Fucales which is useful in sugar chain engineering; a process for producing this enzyme; an oligosaccharide obtained by treating sulfated fucan with the enzyme; and production thereof.Type: ApplicationFiled: January 17, 2003Publication date: November 17, 2005Applicant: TAKARA BIO INCInventors: Takeshi Sakai, Hitomi Amarume, Katsushige Ikai, Ikunoshin Kato
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Publication number: 20050202064Abstract: A product obtained by heating at least one substance selected from the following (a), (b) and (c). (a) uronic acid or uronic acid derivative; (b) a saccharide compound containing uronic acid or a saccharide compound containing uronic acid derivative; and (c) a substance containing a saccharide compound containing uronic acid or a substance containing a saccharide compound containing uronic acid derivative; and food, beverage or a pharmaceutical agent which is characterized in containing the above-mentioned heat-treated product.Type: ApplicationFiled: April 26, 2005Publication date: September 15, 2005Inventors: Nobuto Koyama, Hiroaki Sagawa, Eiji Kobayashi, Tatsuji Enoki, Hua-Kang Wu, Eiji Nishiyama, Suzu Deguchi, Katsushige Ikai, Hiromu Ohnogi, Motoko Ueda, Akihiro Kondo, Ikunoshin Kato
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Patent number: 6927289Abstract: A smaller molecule obtainable by allowing a sulfated fucan-digesting enzyme which digests a novel sulfated polysaccharide derived from an alga belonging to Laminariales to act on a sulfated fucan, and a method for producing the same.Type: GrantFiled: October 28, 2003Date of Patent: August 9, 2005Assignee: Takara Bio Inc.Inventors: Takeshi Sakai, Hitomi Amarume, Takashi Kawai, Kaoru Kojima, Kazuo Shimanaka, Katsushige Ikai, Ikunoshin Kato
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Patent number: 6911432Abstract: Medicinal compositions for treating, ameliorating or preventing diseases with sensitivity to 3,6-anhydrogalactopyranose are represented by formula (I): These compositions include foods, drinks, cosmetics, etc. containing as the active ingredient at least one such compound, its aldehyde, its hydrate and 2-O-methylated derivatives thereof and soluble sugar compounds containing the above compound. These compounds show an apoptosis-inducing activity, carcinostatic activity and inhibitory activities on the production of active oxygen, lipid peroxide radicals and NO, which makes them useful also as the active ingredient of antioxidants and preservatives.Type: GrantFiled: August 27, 2002Date of Patent: June 28, 2005Inventors: Tatsuji Enoki, Hiroaki Sagawa, Takanari Tominaga, Eiji Nishiyama, Nobuto Koyama, Takeshi Sakai, Fu-Gong Yu, Katsushige Ikai, Ikunoshin Kato
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Publication number: 20050119191Abstract: Medicinal compositions for treating, ameliorating or preventing diseases with sensitivity to 3,6-anhydrogalactopyranose represented by formula (1): foods, drinks, cosmetics, etc. containing as the active ingredient at least one member selected from the group consisting of the above-mentioned compound, its aldehyde, its hydrate and 2-O-methylated derivatives thereof and soluble sugar compounds containing the above compound. This compound also shows, for example, an apoptosis-inducing activity, a carcinostatic activity and inhibitory activities on the production of active oxygen, lipid peroxide radicals and NO, which makes it useful also as the active ingredient of antioxidants and preservatives.Type: ApplicationFiled: January 13, 2005Publication date: June 2, 2005Applicant: Takara Shuzo Co., Ltd.Inventors: Tatsui Enoki, Hiroaki Sagawa, Takanari Tominaga, Eiji Nishiyama, Nobuto Koyama, Takeshi Sakai, Fu-Gong Yu, Katsushige Ikai, Ikunoshin Kato
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Publication number: 20050090456Abstract: An enzyme which decomposes a sulfated fucoglucuronomannan and is useful in the field of glycotechnology; a process for producing the enzyme; a fucoidan fraction reduced in the number of the kinds of molecules and useful as a reagent in glycotechnology; a sulfated fucoglucuronomannan oligosaccharide; and processes for producing the fraction and oligosaccharide.Type: ApplicationFiled: April 18, 2002Publication date: April 28, 2005Inventors: Takeshi Sakai, Hitomi Kimura, Katsushige Ikai, Ikunoshin Kato
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Publication number: 20050049221Abstract: Food or beverage where fucoidan which is derived from a fucoidan-containing substance is contained therein, added thereto and/or diluted therein. Food or beverage where fucoidan which is derived from a fucoidan-containing substance and where algins are reduced or eliminated is contained therein. Apoptosis-inducing food or beverage where an effective amount of fucoidan having an apoptosis-inducing ability is contained therein.Type: ApplicationFiled: April 8, 2003Publication date: March 3, 2005Inventors: Yoshihisa Umeda, Hiroshi Kihara, Katsushige Ikai, Ikunoshin Kato
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Patent number: 6809091Abstract: A method for the manufacture of a substance having an apoptosis-inducing ability characterized in including a step of subjecting at least one compound selected from the following (a), (b), (c) and (d) [excluding uronic acid and/or uronic acid derivatives; and compounds which contain uronic acid and/or uronic acid derivatives] to a heating treatment: (a) pentose; (b) pentose derivatives; (c) compounds containing pentose; (d) compounds containing pentose derivatives.Type: GrantFiled: June 28, 2000Date of Patent: October 26, 2004Assignee: Takara Bio Inc.Inventors: Yoko Tatsumi, Hiroaki Sagawa, Hiromu Ohnogi, Eiji Kobayashi, Hua-Kang Wu, Nobuto Koyama, Katsushige Ikai, Ikunoshin Kato
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Patent number: 6803367Abstract: A substance for inducing apoptosis represented by specific formulae. A pharmaceutical composition which can be used for an anticancer agent containing said substance.Type: GrantFiled: October 1, 2002Date of Patent: October 12, 2004Assignee: Takara Shuzo Co., Ltd.Inventors: Tatsuji Enoki, Nobuto Koyama, Katsushige Ikai, Ikunoshin Kato
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Publication number: 20040146995Abstract: A smaller molecule obtainable by allowing a sulfated fucan-digesting enzyme which digests a novel sulfated polysaccharide derived from an alga belonging to Laminariales to act on a sulfated fucan, and a method for producing the same.Type: ApplicationFiled: October 28, 2003Publication date: July 29, 2004Applicant: TAKARA BIO INC.Inventors: Takeshi Sakai, Hitomi Amarume, Takashi Kawai, Kaoru Kojima, Kazuo Shimanaka, Katsushige Ikai, Ikunoshin Kato
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Patent number: 6720419Abstract: A smaller molecule obtainable by allowing a sulfated fucan-digesting enzyme which digests a novel sulfated polysaccharide derived from an alga belonging to Laminariales to act on a sulfated fucan, and a method for producing the same.Type: GrantFiled: October 24, 2002Date of Patent: April 13, 2004Assignee: Takara Bio Inc.Inventors: Takeshi Sakai, Hitomi Amarume, Takashi Kawai, Kaoru Kojima, Kazuo Shimanaka, Katsushige Ikai, Ikunoshin Kato