Patents by Inventor Kazuaki Matsumura

Kazuaki Matsumura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11812739
    Abstract: Provided are a vitrification stabilizer for an animal cell cryopreservation fluid, and an animal cell cryopreservation fluid which exhibits superior vitrification capabilities due to the animal cell cryopreservation fluid containing the vitrification stabilizer for an animal cell cryopreservation fluid. The vitrification stabilizer for an animal cell cryopreservation fluid contains: an amphoteric polymer compound selected from the group consisting of (a) a carboxylated amphoteric polymer compound obtained by reacting ?-poly-L-lysine with butyl succinic anhydride, (b) a carboxylated amphoteric polymer compound obtained by reacting ?-poly-L-lysine with butyl succinic anhydride and succinic anhydride, or (c) a carboxylated amphoteric polymer compound obtained by reacting ?-poly-L-lysine with a compound represented by formula I; and (d) a sucrose polymer macromolecule to which epichlorohydrin has been crosslinked.
    Type: Grant
    Filed: February 15, 2017
    Date of Patent: November 14, 2023
    Assignee: JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Kazuaki Matsumura, Toshiaki Naka
  • Patent number: 11530286
    Abstract: The present invention provides a protein aggregation inhibitor for use in preventing aggregation of a protein, containing a crosslinked polymer obtained by polymerizing polymerizable polymer components containing a sulfobetaine polymer obtained by polymerizing monomer components containing a sulfobetaine monomer, the sulfobetaine monomer, and a crosslinkable monomer.
    Type: Grant
    Filed: May 30, 2017
    Date of Patent: December 20, 2022
    Assignees: OSAKA ORGANIC CHEMICAL INDUSTRY LTD., JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Kazuaki Matsumura, Rajan Robin, Yoko Taniyama, Yoshiyuki Saruwatari
  • Patent number: 11197473
    Abstract: Provided are a vitrification stabilizer for animal cell cryopreservation fluid, and an animal cell cryopreservation fluid that exhibits superior vitrification capacity due to containing said vitrification stabilizer for animal cell cryopreservation fluid. The vitrification stabilizer for animal cell cryopreservation fluid contains an amphoteric polymer compound selected from the group consisting of: (a) an amphoteric polymer compound obtained by reacting ?-poly-L-lysine with butyl succinic acid anhydride and performing carboxylation; (b) an amphoteric polymer compound obtained by reacting ?-poly-L-lysine with butyl succinic acid anhydride and succinic acid anhydride, and performing carboxylation; and (c) an amphoteric polymer compound obtained by reacting ?-poly-L-lysine with a compound represented by formula (I) and performing carboxylation.
    Type: Grant
    Filed: July 19, 2016
    Date of Patent: December 14, 2021
    Assignee: JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Kazuaki Matsumura, Manato Suzuki
  • Publication number: 20210322944
    Abstract: A hydrogel of which the degradation is accurately controlled can be provided by a photodegradable hydrogel production method, the method comprising the steps of: reacting ?-glucan having a weight average molecular weight of 2000 to 200,000 with a compound represented by formula I to introduce a group represented by formula II into the ?-glucan; oxidizing the ?-glucan having, introduced therein, the group represented by formula II with periodic acid or a periodate salt to introduce an aldehyde group into the ?-glucan; and adding aminated carrageenan gel beads having polydopamine particles embedded therein to a gelling agent which has been prepared by introducing a group represented by formula II and an aldehyde group into ?-glucan, and then causing the crosslinking reaction of the resultant product with a polythiol-type reducing agent to form the hydrogel.
    Type: Application
    Filed: July 19, 2019
    Publication date: October 21, 2021
    Applicant: JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Kazuaki MATSUMURA, Punnida NONSUWAN
  • Patent number: 10995160
    Abstract: The present invention provides a protein aggregation inhibitor for use in preventing aggregation of a protein, which contains a terminal sulfanyl group-containing sulfobetaine polymer having a repeat unit derived from a sulfobetaine monomer represented by the formula (II), and a noble metal particle, and in which the terminal sulfanyl group-containing sulfobetaine polymer is chemisorbed on the noble metal particle by the sulfanyl group (the groups in the following formula are as defined in the DESCRIPTION).
    Type: Grant
    Filed: June 29, 2017
    Date of Patent: May 4, 2021
    Assignees: OSAKA ORGANIC CHEMICAL INDUSTRY LTD., JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Kazuaki Matsumura, Rajan Robin, Yoko Taniyama, Yoshiyuki Saruwatari
  • Publication number: 20210084891
    Abstract: Provided are a vitrification stabilizer for an animal cell cryopreservation fluid, and an animal cell cryopreservation fluid which exhibits superior vitrification capabilities due to the animal cell cryopreservation fluid containing the vitrification stabilizer for an animal cell cryopreservation fluid. The vitrification stabilizer for an animal cell cryopreservation fluid contains: an amphoteric polymer compound selected from the group consisting of (a) a carboxylated amphoteric polymer compound obtained by reacting ?-poly-L-lysine with butyl succinic anhydride, (b) a carboxylated amphoteric polymer compound obtained by reacting ?-poly-L-lysine with butyl succinic anhydride and succinic anhydride, or (c) a carboxylated amphoteric polymer compound obtained by reacting ?-poly-L-lysine with a compound represented by formula I; and (d) a sucrose polymer macromolecule to which epichlorohydrin has been crosslinked.
    Type: Application
    Filed: February 15, 2017
    Publication date: March 25, 2021
    Applicant: JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Kazuaki Matsumura, Toshiaki Naka
  • Publication number: 20200332044
    Abstract: The present invention provides a protein aggregation inhibitor for use in preventing aggregation of a protein, containing a crosslinked polymer obtained by polymerizing polymerizable polymer components containing a sulfobetaine polymer obtained by polymerizing monomer components containing a sulfobetaine monomer, the sulfobetaine monomer, and a crosslinkable monomer.
    Type: Application
    Filed: May 30, 2017
    Publication date: October 22, 2020
    Applicants: OSAKA ORGANIC CHEMICAL INDUSTRY LTD., JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Kazuaki MATSUMURA, Rajan ROBIN, Yoko TANIYAMA, Yoshiyuki SARUWATARI
  • Patent number: 10308386
    Abstract: A medicine dispensing apparatus fills a vial having a polygonal cross-sectional shape with medicines to dispense the medicines. The apparatus contains a stocker, a first vial transporting unit, a vial orienting unit, a labeling unit, a second vial transporting unit, a medicine filling unit, and a vial discharging window. The stocker stores the vial. The first vial transporting unit transports the vial from the stocker to the labeling unit. The vial orienting unit adjusts an orientation of the vial. The labeling unit labels the vial. The second vial transporting unit transports the vial from the labeling unit to the medicine filling unit. The medicine filling unit fills the vial with the medicines. The second vial transporting unit further transports the vial from the medicine filling unit to the vial discharging window, where the vial is discharged through the vial discharging window.
    Type: Grant
    Filed: May 31, 2012
    Date of Patent: June 4, 2019
    Assignee: YUYAMA MANUFACTURING Co., LTD.
    Inventors: Naoki Koike, Takafumi Imai, Kazuaki Matsumura, Takuya Tsugui, Kazunori Tsukamoto
  • Publication number: 20190161563
    Abstract: The present invention provides a protein aggregation inhibitor for use in preventing aggregation of a protein, which contains a terminal sulfanyl group-containing sulfobetaine polymer having a repeat unit derived from a sulfobetaine monomer represented by the formula (II), and a noble metal particle, and in which the terminal sulfanyl group-containing sulfobetaine polymer is chemisorbed on the noble metal particle by the sulfanyl group (the groups in the following formula are as defined in the DESCRIPTION).
    Type: Application
    Filed: June 29, 2017
    Publication date: May 30, 2019
    Applicants: OSAKA ORGANIC CHEMICAL INDUSTRY LTD., JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Kazuaki MATSUMURA, Rajan ROBIN, Yoko TANIYAMA, Yoshiyuki SARUWATARI
  • Publication number: 20180160676
    Abstract: Provided are a vitrification stabilizer for animal cell cryopreservation fluid, and an animal cell cryopreservation fluid that exhibits superior vitrification capacity due to containing said vitrification stabilizer for animal cell cryopreservation fluid. The vitrification stabilizer for animal cell cryopreservation fluid contains an amphoteric polymer compound selected from the group consisting of: (a) an amphoteric polymer compound obtained by reacting ?-poly-L-lysine with butyl succinic acid anhydride and performing carboxylation; (b) an amphoteric polymer compound obtained by reacting ?-poly-L-lysine with butyl succinic acid anhydride and succinic acid anhydride, and performing carboxylation; and (c) an amphoteric polymer compound obtained by reacting ?-poly-L-lysine with a compound represented by formula (I) and performing carboxylation.
    Type: Application
    Filed: July 19, 2016
    Publication date: June 14, 2018
    Applicant: JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Kazuaki Matsumura, Manato Suzuki
  • Publication number: 20180118859
    Abstract: Provided is a protein aggregation inhibitor capable of inhibiting aggregation of a protein even when the protein is heated, and further, capable of inhibiting a decrease in the protein activity even when the protein is heated, which characteristically contains a sulfobetaine polymer obtained by polymerizing monomer components containing sulfobetaine monomer represented by the formula (I): wherein R1 is a hydrogen atom or a methyl group, R2 is an alkylene group having a carbon number of 1-4, R3 is an alkyl group having a carbon number of 1-4, R4 is an alkylene group having a carbon number of 1-4, and X is an —NH— group or an —O— group.
    Type: Application
    Filed: May 10, 2016
    Publication date: May 3, 2018
    Applicants: OSAKA ORGANIC CHEMICAL INDUSTRY LTD., JAPAN ADVANCED INSTITUTE OF SCIENCE AND TECHNOLOGY
    Inventors: Kazuaki MATSUMURA, Rajan ROBIN, Tsuyoshi FURUKAWA, Kentaro MAEHARA, Yoshiyuki SARUWATARI
  • Patent number: 9826732
    Abstract: A composition for cryopreservation of cells and tissues of human and other animals in a safe manner without using toxic substances such as DMSO, as well as for freeze preserving or freeze-drying of foods and pharmaceuticals. In embodiments, ?-poly-L-lysine is reacted with succinic anhydride so that 60% or more of amino groups are blocked; and, thus obtained polymer compound is added to Dulbecco-modified eagle MEM culture medium (DMEM) on market sale to form a cryopreservation liquid. In embodiments for foods or pharmaceuticals, the ?-poly-L-lysine derivative was added by 0.5-10 wt % to curb freeze concentration.
    Type: Grant
    Filed: June 30, 2016
    Date of Patent: November 28, 2017
    Assignee: Bio Verde Inc.
    Inventors: Kazuaki Matsumura, Hajime Sugai, Suong-Hyu Hyon
  • Patent number: 9603355
    Abstract: A composition for cryopreservation of cells and tissues of human and other animals in a safe manner without using toxic substances such as DMSO, as well as for freeze preserving or freeze-drying of foods and pharmaceuticals. In embodiments, ?-poly-L-lysine is reacted with succinic anhydride so that 60% or more of amino groups are blocked; and, thus obtained polymer compound is added to Dulbecco-modified eagle MEM culture medium (DMEM) on market sale to form a cryopreservation liquid. In embodiments for foods or pharmaceuticals, the ?-poly-L-lysine derivative was added by 0.5-10 wt % to curb freeze concentration.
    Type: Grant
    Filed: April 30, 2014
    Date of Patent: March 28, 2017
    Assignee: BIO VERDE INC.
    Inventors: Kazuaki Matsumura, Hajime Sugai, Suong-Hyu Hyon
  • Publication number: 20160309706
    Abstract: A composition for cryopreservation of cells and tissues of human and other animals in a safe manner without using toxic substances such as DMSO, as well as for freeze preserving or freeze-drying of foods and pharmaceuticals. In embodiments, ?-poly-L-lysine is reacted with succinic anhydride so that 60% or more of amino groups are blocked; and, thus obtained polymer compound is added to Dulbecco-modified eagle MEM culture medium (DMEM) on market sale to form a cryopreservation liquid. In embodiments for foods or pharmaceuticals, the ?-poly-L-lysine derivative was added by 0.5-10 wt % to curb freeze concentration.
    Type: Application
    Filed: June 30, 2016
    Publication date: October 27, 2016
    Inventors: Kazuaki MATSUMURA, Hajime SUGAI, Suong-Hyu HYON
  • Patent number: 8979649
    Abstract: To provide an information processing device capable of improving operability in an information processing device in which when a position in any of a plurality of determination areas for a plurality of selected image candidates is designated by a user, a selected image candidate corresponding to the determination area is designated as a selected image. A designated position obtaining unit (106) obtains a position designated by a user. A designation unit (110), when the position obtained by the designated position obtaining unit (106) is included in a determination area for a selected image candidate, designates the selected image candidate as a selected image.
    Type: Grant
    Filed: October 22, 2009
    Date of Patent: March 17, 2015
    Assignee: Konami Digital Entertainment Co., Ltd.
    Inventors: Hiroyuki Tomita, Kazuaki Matsumura, Tomomi Tsubakisawa
  • Publication number: 20140243426
    Abstract: A composition for cryopreservation of cells and tissues of human and other animals in a safe manner without using toxic substances such as DMSO, as well as for freeze preserving or freeze-drying of foods and pharmaceuticals. In embodiments, ?-poly-L-lysine is reacted with succinic anhydride so that 60% or more of amino groups are blocked; and, thus obtained polymer compound is added to Dulbecco-modified eagle MEM culture medium (DMEM) on market sale to form a cryopreservation liquid. In embodiments for foods or pharmaceuticals, the ?-poly-L-lysine derivative was added by 0.5-10 wt % to curb freeze concentration.
    Type: Application
    Filed: April 30, 2014
    Publication date: August 28, 2014
    Applicant: Bio Verde Inc.
    Inventors: Kazuaki MATSUMURA, Hajime SUGAI, Suong-Hyu HYON
  • Patent number: 8485898
    Abstract: To provide a game device capable of allowing a user, when selecting any selected image candidate, to experience a real feeling of the relationship with another selected image candidate. A determination unit (70a) determines whether or not the designated area designated by a user is included in the determination area for a selected image candidate. When the designated area is included in the determination area, the designation unit (72a) designates the selected image candidate corresponding to the determination area as a selected image. A determination area control unit (68) changes the size of a determination area for another selection candidate image, based on a parameter stored so as to be correlated to a combination of the selected image candidate designated as a selected image and the other selected image candidate.
    Type: Grant
    Filed: October 22, 2009
    Date of Patent: July 16, 2013
    Assignee: Konami Digital Entertainment Co., Ltd.
    Inventors: Hiroyuki Tomita, Kazuaki Matsumura, Tomomi Tsubakisawa
  • Patent number: 8360891
    Abstract: In a game device (200), a memory unit (201) stores a position of a player character, a position of an enemy character, an elapsed time up to a present time after the enemy character has appeared, and candidates of a position where a new enemy character is to appear. A measuring unit (202) measures an elapsed time up to a present time after the enemy character has appeared, and stores the measured elapsed time in the memory unit (201). A calculating unit (203) calculates a reference distance which becomes a determination criterion for a position where a new enemy character appears based on the stored elapsed time. The reference distance monotonically increases relative to the increasing of the elapsed time. An appearance setting unit (204) selects a candidate having a distance to the player character closest to the reference distance among the candidates stored in the memory unit (201), and causes a new enemy character to appear at the selected candidate position.
    Type: Grant
    Filed: December 17, 2008
    Date of Patent: January 29, 2013
    Assignee: Konami Digital Entertainment Co., Ltd.
    Inventor: Kazuaki Matsumura
  • Publication number: 20120304596
    Abstract: A medicine dispensing apparatus fills a vial having a polygonal cross-sectional shape with medicines to dispense the medicines. The apparatus contains a stocker, a first vial transporting unit, a vial orienting unit, a labeling unit, a second vial transporting unit, a medicine filling unit, and a vial discharging window. The stocker stores the vial. The first vial transporting unit transports the vial from the stocker to the labeling unit. The vial orienting unit adjusts an orientation of the vial. The labeling unit labels the vial. The second vial transporting unit transports the vial from the labeling unit to the medicine filling unit. The medicine filling unit fills the vial with the medicines. The second vial transporting unit further transports the vial from the medicine filling unit to the vial discharging window, where the vial is discharged through the vial discharging window.
    Type: Application
    Filed: May 31, 2012
    Publication date: December 6, 2012
    Applicant: YUYAMA MANUFACTURING Co., LTD
    Inventors: Naoki KOIKE, Takafumi Imai, Kazuaki Matsumura, Takuya Tsugui, Kazunori Tsukamoto
  • Publication number: 20120019472
    Abstract: To provide an information processing device capable of improving operability in an information processing device in which when a position in any of a plurality of determination areas for a plurality of selected image candidates is designated by a user, a selected image candidate corresponding to the determination area is designated as a selected image. A designated position obtaining unit (106) obtains a position designated by a user. A designation unit (110), when the position obtained by the designated position obtaining unit (106) is included in a determination area for a selected image candidate, designates the selected image candidate as a selected image.
    Type: Application
    Filed: October 22, 2009
    Publication date: January 26, 2012
    Applicant: Knoami Digital Entertainment Co.,Ltd.
    Inventors: Hiroyuki Tomita, Kazuaki Matsumura, Tomomi Tsubakisawa