Abstract: There is provided a vinyl alcohol-based polymer having an olefin in side chain, comprising 0.001 to 10 mol % of a structural unit represented by Formula (1) based on the total amount of structural units, wherein the total carbon number of X, R1, R2, R3 and R4 is 2 or more. The vinyl alcohol-based polymer having an olefin in side chain has excellent storage stability, good solubility in water or an organic solvent even after thermal treatment, and excellent reactivity to high energy beam.

Abstract: The present invention provides a resin composition satisfying both high crystallinity and excellent flexibility while ensuring desirable workability. The present invention relates to a resin composition comprising a vinyl alcohol polymer (A) and a copolymer (B), wherein the copolymer (B) comprises a vinyl alcohol polymer (B-1) and a diene polymer (B-2), and has a content ratio of 10 to 70 mass % with respect to a total mass of the vinyl alcohol polymer (A) and the copolymer (B), the resin composition having a powder or pellet form, and an average particle diameter of 50 to 4,000 ?m.

Abstract: The present invention relates to a vinyl alcohol-based polymer having an olefin in side chain, comprising a vinyl alcohol unit and a structural unit represented by Formula (I), wherein X represents a divalent saturated hydrocarbon group with 1 to 6 carbon atoms, optionally having a branched structure; Y represents a hydrogen atom or a saturated hydrocarbon group with 1 to 6 carbon atoms, optionally having a branched structure; and Z represents a hydrogen atom or a methyl group. Thus, there is provided a vinyl alcohol-based polymer having an olefin in side chain exhibiting higher water solubility even after thermal treatment, higher storage stability, and higher reactivity to high energy beam, and a method for producing it.

Abstract: The present invention provides a dental polymerizable composition that requires less discharging force, is easily formable, has low polymerization shrinkage stress during curing, and exhibits high stain resistance and surface gloss when cured. The present invention relates to a dental polymerizable composition including a (meth)acrylic block copolymer (A), a polymerizable monomer (B), and a polymerization initiator (C). The (meth)acrylic block copolymer (A) consists of a (meth)acrylic polymer block (a) having a curable functional group and a (meth)acrylic polymer block (b) having no curable functional group.

Abstract: Provided is a monoclonal antibody or a fragment thereof that selectively inhibits the enzymatic activity of vascular endothelial lipase and pharmaceutical compositions containing the same as an active ingredient useful for the treatment of arteriosclerosis or metabolic syndrome.

Abstract: A polyvinyl alcohol is produced in a method comprising: a polymerization step comprising polymerizing vinyl ester monomers by controlled radical polymerization in the presence of a radical initiator and an organic cobalt complex to obtain a polymer solution containing a polyvinyl ester; an extraction step comprising extracting a cobalt complex from the polymer solution by contacting an aqueous solution containing a water-soluble ligand with the polymer solution; and a saponification step comprising saponifying the polyvinyl ester after the extraction step to obtain a polyvinyl alcohol. A method for producing a polyvinyl alcohol is thus provided that has a narrow molecular weight distribution and a high number-average molecular weight with good hue and further good solubility in water.

Abstract: A polyvinyl alcohol has a number-average molecular weight (Mn) from 4,400 to 440,000, a molecular weight distribution (Mw/Mn) from 1.05 to 1.70, a degree of saponification from 80 to 99.99 mol %, and a carbon-carbon double bond content (X) of 0.1 mol % or less based on total monomer units, and satisfying a formula (1) below. A polyvinyl alcohol, having a narrow molecular weight distribution and a high number-average molecular weight with good hue, and a method for producing the same are thus provided.

Abstract: Provided is a monoclonal antibody or a fragment thereof that selectively inhibits the enzymatic activity of vascular endothelial lipase and pharmaceutical compositions containing the same as an active ingredient useful for the treatment of arteriosclerosis or metabolic syndrome.

Abstract: A bend sensor comprising a sensor section in which a polymer electrolyte film is sandwiched between a pair of electrode films, wherein each of the electrode films contains: a block copolymer (Z) having a polymer block (S) composed of a structural unit derived from an aromatic vinyl compound, and containing an ion-conducting group, and an amorphous polymer block (T) composed of a structural unit derived from an unsaturated aliphatic hydrocarbon; and a conducting particle; which block copolymer (Z) forms a lamellar structure, which bend sensor therefore allows generation of enhanced voltage between the electrode films when deformation of the sensor occurs as it follows movement of an object, is provided.

Abstract: The present invention provides a dental polymerizable composition that requires less discharging force, is easily formable, has low polymerization shrinkage stress during curing, and exhibits high stain resistance and surface gloss when cured. The present invention relates to a dental polymerizable composition including a (meth)acrylic block copolymer (A), a polymerizable monomer (B), and a polymerization initiator (C). The (meth)acrylic block copolymer (A) consists of a (meth)acrylic polymer block (a) having a curable functional group and a (meth)acrylic polymer block (b) having no curable functional group.

Abstract: Provided is a monoclonal antibody or a fragment thereof that selectively inhibits the enzymatic activity of vascular endothelial lipase and pharmaceutical compositions containing the same as an active ingredient useful for the treatment of arteriosclerosis or metabolic syndrome.

Abstract: The invention provides active energy ray curable compositions which exhibit good curability with active energy rays and which have a low viscosity to attain excellent application properties when applied as materials such as adhesives or coatings onto substrates and can give highly flexible cured products upon irradiation with active energy rays.

Abstract: Provided is a monoclonal antibody or a fragment thereof that selectively inhibits the enzymatic activity of vascular endothelial lipase and pharmaceutical compositions containing the same as an active ingredient useful for the treatment of arteriosclerosis or metabolic syndrome.

Abstract: The present invention provides a composition to for production of electrode films contained in a sensor formed by sandwiching a polymer electrolyte film between two electrode films, which composition can increase the intensity of the electric signal that can be output by the sensor. The composition comprises: a diblock polymer (A) having a structure in which, in a diblock polymer (A0) having no ion-conducting group composed of a polymer block (S0) containing a structural unit derived from an aromatic vinyl compound having a number average molecular weight of not less than 20,000 and an amorphous polymer block (T) containing a structural unit derived from an unsaturated aliphatic hydrocarbon, an ion-conducting group(s) is/are introduced to the polymer block (S0); a hydrocarbon solvent (B); an organic solvent (C) having at least one functional group selected from the group consisting of hydroxyl, carbonyl, alkoxycarbonyl, and amide; and a conductive filler (D).

Abstract: Provided is a monoclonal antibody or a fragment thereof that selectively inhibits enzyme activity of EL and pharmaceutical compositions containing the same as an active ingredient useful for the treatment of arteriosclerosis or metabolic syndrome.

Abstract: Provided is a monoclonal antibody or a fragment thereof that selectively inhibits the enzymatic activity of vascular endothelial lipase and pharmaceutical compositions containing the same as an active ingredient useful for the treatment of arteriosclerosis or metabolic syndrome.

Abstract: A method for producing a (meth)acrylate copolymer via anionic polymerization of a mixture of a di(meth)acrylate and an alkyl (meth)acrylate in the presence of an organolithium compound, a tertiary organoaluminum compound, and at least one Lewis base selected from ethers and tertiary polyamines. The (meth)acrylate copolymer produced has a (meth)acryloyl groups in a side chain.

Abstract: [Object] To produce a (meth)acrylate copolymer useful as a photocurable resin composition at a temperature favorable to industrial production in a short time. [Solution] There is provided a method for producing a (meth)acrylate copolymer (X), including anionic polymerization of a mixture of a di(meth)acrylate represented by the following general formula (1) and an alkyl (meth)acrylate represented by the following general formula (2) in the presence of an organolithium compound (L), a tertiary organoaluminum compound (A) having a chemical structure represented by the general formula Al—O—Ar (wherein Ar denotes an aromatic ring) in its molecules, and at least one Lewis base (B) selected from the group consisting of ethers and tertiary polyamines.

Abstract: Provided is a monoclonal antibody or a fragment thereof that selectively inhibits enzyme activity of EL and pharmaceutical compositions containing the same as an active ingredient useful for the treatment of arteriosclerosis or metabolic syndrome.

Abstract: The invention is intended to provide a pharmaceutical composition for treating or preventing obesity or type II diabetes and a method for treatment for them. A pharmaceutical composition comprising an Acsl-1 inhibitor of this invention as an active ingredient is useful for prevention or treatment of obesity or type II diabetes.