Abstract: According to the present invention, there can be provided a structure preventing the nonspecific adsorption, and a target substance-detecting element and a target substance-detecting kit. A first aspect of the present invention is a structure including: a substrate; and a membrane, present on the surface of the substrate, having a polymer of a monomer represented by the following General Formula (1) or (2): (wherein R represents H or CH3; x represents an integer of 2 to 5, and y represents an integer of 1 to 7, with the proviso that x+y=an integer of 3 to 10), and (wherein R1=H or CH3, and R2 represents O or NH; a represents an integer of 2 to 5, and b represents an integer of 1 to 7, with the proviso that a+b=an integer of 3 to 10.

Abstract: An information obtaining method for obtaining information about a mass of a component of an analyte using a time of flight mass spectrometer and obtaining information about a distribution state of the component based on the obtained information about the mass includes the step of: (1) adding a self-reactive substance to the analyte on a base to facilitate ionization of the component; (2) irradiating the analyte with a primary beam in the presence of the self-reactive substance, thereby ionizing the components and allowing resulting ions to fly; (3) obtaining information about mass of the flying ions using the time of flight mass spectrometer; and (4) obtaining information about the distribution state of the component on the base based on the information about the mass.

Abstract: A pre-treatment method for analyzing a specified portion in a specimen composed of a biological tissue includes the steps of preparing a specimen to be analyzed, determining a specified portion in the specimen; and applying an analysis inhibitor to a portion except the specified portion of the specimen using a droplet spray method.

Abstract: A method for obtaining information on a mass of an object by time-of-flight mass spectrometry. This method includes placing colloidal metal particles for promoting ionization of the object inside the object at a depth ranging from 0.1 nm to 100 nm in opposition to a primary beam for the ionization; irradiating the object with the primary beam selected from the group of ions, neutral particles, and electrons, which can be focused, pulsed, and are capable of scanning, and laser beams, which can be focused, pulsed, and are capable of scanning to ionize a constituent of the object and to allow the ionized constituent to fly out of the object; and obtaining information on the mass of the flying constituent of the object by time-of-flight mass spectrometry.

Abstract: A detection device for detecting a target substance in a specimen comprises a flow channel for delivering the specimen, a coil surrounding the flow channel, and a reaction region being placed in a portion of the flow channel surrounded by the coil outside and holding a first trap substance immobilized thereon for trapping the target substance, the coil bring about a change of a physical property thereof when the target substance is trapped by the first trap substance and a magnetic body having a second trap substance on the surface thereof which second trap substance is capable of specifically binding to the target substance is trapped by the target substance.

Abstract: To provide an organic substance-immobilized structure employing a novel immobilizing technique and a manufacturing method thereof using the novel immobilizing technique, where, when an organic substance, particularly a biological substance is immobilized on the surface of a substrate, the organic substance, particularly the biological substance can be stably immobilized on the surface of the substrate through orientation of the organic substance, particularly the biological substance suitable for exerting physiological functions thereof. At least part of the substrate's surface is constructed of one or more substrates containing aluminum oxide. The immobilization of the organic substance to the surface of the substrate is carried out by binding at least part of the binding domain to the surface of the substrate through a binding domain containing a peptide having an affinity to aluminum oxide and composed of at least one or more amino acids, which is coupled with the organic substance.

Abstract: A method is provided by which a reagent is provided to a living sample, including contacting a thin-film containing a porous body with a living sample containing cells or tissues, and discharging a solution containing at least one or more reagents to a non-contact side of the thin-film by ink-jet to provide the solution to the specific area of the living sample through pores on the thin-film, wherein the smaller diameter of the pores on the porous body relative to the diameter of cells in the living sample enables the reagent to be provided to each individual cell separately. According to this method, the reagent and the reaction product can be fixed while maintaining positioning information of the target substance in the living sample, as a pretreatment for analyzing with high positioning accuracy the target substance in each individual cell in the living sample.

Abstract: A sample is sliced obliquely with a blade provided with a metal thin film on the surface, and the slice of the sample adhering to the blade surface is subjected to mass spectrometry. As a result, the section of the sliced sample can be analyzed immediately by mass spectrometry with high sensitivity.

Abstract: The invention is to provide a magnetic sensor capable of detecting magnetic particles over a wide range of number and of suppressing an increase in a detection area. The magnetic sensor includes a detection part, a selecting device connected electrically to an end of the detecting part, and a sensing amplifier for receiving a signal from the detecting part, wherein the detecting part includes at least two magnetoresistive films serially connected.

Abstract: A biological tissue processing substrate for fixing proteins in a biological tissue or degradation products of the proteins, the substrate comprising: a porous body that forms a contact surface with the biological tissue, the porous body holding in pores an enzyme for obtaining the proteins or the degradation products of the proteins from the biological tissue, wherein the proteins or the degradation products obtained by the action of the enzyme are brought into contact with a member consisting of a metal.

Abstract: An information acquisition method for acquiring information on a target object, that includes a step of promoting ionization of the target object using a substance for promoting ionization of the target object to cause the target object to emit, and a step of acquiring information on the mass of the flew target object using time-of-flight secondary ion mass spectrometry.

Abstract: A detection device for detecting a target substance in a specimen comprises a flow channel for delivering the specimen, a coil surrounding the flow channel, and a reaction region being placed in a portion of the flow channel surrounded by the coil outside and holding a first trap substance immobilized thereon for trapping the target substance, the coil bring about a change of a physical property thereof when the target substance is trapped by the first trap substance and a magnetic body having a second trap substance on the surface thereof which second trap substance is capable of specifically binding to the target substance is trapped by the target substance.

Abstract: A registration correction circuit for a solid-state camera having a plurality of solid-state image pickup elements. One of the color video signals produced from the image pickup elements is selected as a reference signal, and pixel data of the color video signals other than the reference signal are electronically moved so that the pixel data of all the color video signals will agree in their positions. Movement of pixels is carried out by using coordinate transformation and interpolation technique: the coordinate transformation is used to shift the pixels by a multiple of 1-pixel pitch; and the interpolation is used to shift the pixels by less than 1-pixel pitch. The spatial frequency components reduced by the interpolation calculations are adaptively enhanced for each pixel in real time.

Abstract: In a microwave integrated circuit, circuit elements such as microstrip coupled lines or interconnecting lines are formed on a separate substrate which is installed vertically between two halves of an input/output transmission-line substrate, or which is installed vertically on the surface of the input/output transmission-line substrate. Microwave integrated circuits with this configuration can be mass-produced at a low cost, can tolerate high applied power levels, and are smaller than conventional microwave integrated circuits.

Abstract: The apparatus of the invention comprises a radar device for measuring the range of an object and the vehicle speed relative to the object, and a vehicle speed sensor for measuring the vehicle roadway speed. A first computing circuit is provided to set up a first minimum distance allowed for the vehicle when approaching a stationary object and a second computing circuit for setting up a second minimum distance allowed for the vehicle approaching an object moving ahead of the vehicle. An alarm will be given either when the range of the stationary object reaches the first minimum distance or that of the moving object reaches the second minimum distance.

Abstract: An apparatus for preventing collision of a vehicle comprisesA device for measuring a distance R from a driving vehicle to an obstacle and a relative velocity V of the driving vehicle to said obstacle;A circuit for generating a damping signal when the relation of the distance R, the relative velocity V and a preset deceleration .alpha. becomes the relation of R < V.sup.2 /2.alpha.;a deceleration detector for detecting the actual deceleration .alpha.' of the driving vehicle;A correction circuit which compares the actual deceleration .alpha.' detected by the deceleration detector with the preset deceleration .alpha. and the damping signal is corrected depending upon the comparative data.

Abstract: A radar apparatus comprises a microwave head portion in which a solid state oscillator, such as a Gunn oscillator, is utilized to generate a transmitting signal wave to be transmitted toward a target as well as a local oscillation signal wave by which an intermediate frequency signal is obtained upon a receipt of a reflected wave from the target. A transmission-reception switch means connected to a hybrid coupler constitutes a switching means for switching the operation of the radar apparatus between a transmitting mode and a receiving mode. A signal processing portion is provided in which the instantaneous amplitude value of the intermediate frequency signal according to a phase variation of the intermediate frequency signal due to the movement of the target is obtained by sampling the intermediate frequency signal with sampling pulses, whereby the velocity and moving direction of the target are determined and, by combining such information, an alarm is actuated.