Abstract: The purpose of this study was to identify the periodontal regeneration factors in enamel protein shown to induce cementum- and osteo-promotive activities in vivo. The cementum regeneration (CR), a part of periodontal regeneration, was examined by using experimental cavities prepared in a buccal dehiscence dog model. The CR activity was found in the aggregate consisted of sheath proteins along with a small amount of amelogenins separated from newly formed secretory enamel. The sheath proteins were purified to be homogeneous, and examined for the alkaline phosphatase (ALP) inducing activity of human periodontal ligament (HPDL) cells. Application of 17 kDa sheath protein induced ALP activity in HPDL cells. Peptides synthesized from the sheath protein sequence also showed ALP inducing activity. The 17 kDa sheath protein has cell differentiation activity.

Abstract: A bonding method includes: preparing a first substrate and a second substrate; forming a liquid coating film by applying a liquid material including silicone to at least one of the first substrate and the second substrate; drying the liquid coating film so as to obtain a bonding film; and developing adhesiveness around a surface of the bonding film by applying energy to the bonding film so as to obtain a bonded body obtained by bonding the first substrate and the second substrate each other with the bonding film interposed between the first substrate and the second substrate. In the device, bonding strength of the bonding film is adjusted by appropriately setting a condition for applying the energy.

Abstract: A bonded body having high dimensional accuracy and manufactured easily without problems which occur in the solid bonding method and a method of manufacturing such a bonded body are provided. The bonded body includes a first base member having a first bonding surface; a second base member having a second bonding surface; and a bonding film through which the first base member and the second base member are boded together, the bonding film having two surfaces each making contact with the first bonding surface and the second bonding surface, the bonding film including a silicone portion containing a silicone material composed of silicone compounds and a plurality of gap members that regulate a distance between the first base member and the second base member, at least a part of the gap members provided in the silicone portion.

Abstract: A bonding method of bonding two base members together through a bonding film having a fine pattern at low cost, and a bonded body with the bonding film which is formed using the bonding method are provided. The bonding method is a method for forming a bonded body in which a first base member and a second base member are bonded together through a bonding film having a predetermined pattern.

Abstract: A separating method of a bonded body, the bonded body including two base members and a bonding film through which the base members are boded together, enabling to easily and efficiently separating the bonded body into the two original base members is provided. Further, the bonding film contains a silicone material composed of silicone compounds. The separating method includes: preparing the bonded body with the bonding film; and applying energy for separation to the bonding film so that cleavage is generated within the bonding film due to breakage of a part of molecular bonds of the silicone compounds, to thereby separate the bonded body into the first and second base members.

Abstract: A bonding sheet having a bonding film that can be firmly bonded to an object with high dimensional accuracy and efficiently bonded to the object at a low temperature, a bonding method which is capable of efficiently bonding such a bonding sheet and the object at a low temperature, and a bonded body formed by firmly bonding the bonding sheet and the object with high dimensional accuracy and therefore being capable of providing high reliability are provided. The bonding sheet is adapted to be bonded to an object. The bonding sheet includes a functional substrate having a specific function and a surface, and a bonding film provided on the side of the surface of the functional substrate, the bonding film containing metal atoms, oxygen atoms bonded to the metal atoms, and leaving groups each bonded to at least one of the metal and oxygen atoms, and having a surface.

Abstract: A base member with a bonding film that can be firmly bonded to an object with high dimensional accuracy and efficiently bonded to the object at a low temperature, a bonding method which is capable of efficiently bonding such a base member and the object at a low temperature, and a bonded body formed by firmly bonding the base member and the object with high dimensional accuracy and therefore being capable of providing high reliability are provided. The base member is adapted to be bonded to an object through the bonding film thereof. The base member includes a substrate, a bonding film containing metal atoms, oxygen atoms bonded to the metal atoms, and leaving groups each bonded to at least one of the metal and oxygen atoms, and having a surface, and an intermediate layer provided between the substrate and the bonding film, the intermediate layer having such a property that its thickness can be changed by applying stress thereto.

Abstract: A reduced-pressure drying apparatus for drying a solvent in a liquid under a reduced pressure by evaporation of the solvent, includes a chamber including a first chamber and a second chamber, the first chamber accommodating work to which a liquid containing a film forming material is applied, the second chamber being coupled to the first chamber through a communicating part; a depressurizing unit depressurizing at least the second chamber; a communicating valve opening and closing the communicating part; and a control unit controlling a reduced pressure state at least of the second chamber by driving the depressurizing unit, the control unit also controlling an opening and closing state of the communicating part by driving the communicating valve.

Abstract: A plasma processing apparatus includes: a first electrode including a hollow penetrated through from an upper end thereof to a lower end thereof; a workpiece stage to place a workpiece; a second electrode arranged opposing to a lower end of the first electrode through the workpiece stage; a processing gas nozzle formed on an outer circumference side of an opening at the lower end of the hollow along a circumferential direction; a power source circuit including a power source applying a voltage between the first electrode and the second electrode; and a gas supply system supplying a processing gas to generate plasma to the processing gas nozzle. The plasma is generated by activating the processing gas that is ejected out of the processing gas nozzle and located around immediately below the opening at the lower end upon voltage application between the first electrode and the second electrode so as to process a surface of the workpiece by the plasma.

Abstract: A reduced-pressure drying method includes: decompressing a second chamber communicated with a first chamber housing a base material coated with a liquid substance containing a solvent to predetermined operative pressure by a decompressing device; leaving the first chamber closed in response to reaching the predetermined operative pressure until the evaporated solvent raising the pressure in the first chamber to predetermined pressure; communicating the first chamber with the pressure raised to the predetermined pressure with the second chamber; and discharging the vapor of the solvent dispersed in the first and the second chambers by the decompressing device.

Abstract: A reduced-pressure drying apparatus for drying a solvent in a liquid under a reduced pressure by evaporation of the solvent, includes a chamber including a first chamber and a second chamber, the first chamber accommodating work to which a liquid containing a film forming material is applied, the second chamber being coupled to the first chamber through a communicating part; a depressurizing unit depressurizing at least the second chamber; a communicating valve opening and closing the communicating part; and a control unit controlling a reduced pressure state at least of the second chamber by driving the depressurizing unit, the control unit also controlling an opening and closing state of the communicating part by driving the communicating valve.

Abstract: The purpose of this study was to identify the periodontal regeneration factors in enamel protein shown to induce cementum- and osteo-promotive activities in vivo. The cementum regeneration (CR), a part of periodontal regeneration, was examined by using experimental cavities prepared in a buccal dehiscence dog model. The CR activity was found in the aggregate consisted of sheath proteins along with a small amount of amelogenins separated from newly formed secretory enamel. The sheath proteins were purified to be homogeneous, and examined for the alkaline phosphatase (ALP) inducing activity of human periodontal ligament (HPDL) cells. Application of 17 kDa sheath protein induced ALP activity in HPDL cells. Peptides synthesized from the sheath protein sequence also showed ALP inducing activity. The 17 kDa sheath protein has cell differentiation activity.

Abstract: A robot controller and its control method use a generic personal computer and a PC operating system.

Abstract: A robot controller and its control method use a generic personal computer and a PC operating system.