Patents by Inventor Kazuhiro Kimura

Kazuhiro Kimura has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20260124176
    Abstract: The present invention addresses the problem of providing an inhibitor for retinochoroidal disorders, in particular, an inhibitor for retinochoroidal scar formation and retinochoroidal atrophy in an epiretinal, intraretinal or subretinal tissue. This problem can be solved by preparing an inhibitor for retinochoroidal disorders which comprises, as an active ingredient, (E)-4-(2-{3-[(1H-pyrazol-1-yl)methyl]-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene-2-yl}vinyl)benzoic acid, an ester thereof or a salt of the same. The inhibitor for retinochoroidal disorders can inhibit collagen atrophy of retinal pigment epithelium cells, fibroblasts, glial cells and the like and thus inhibit retinochoroidal disorders.
    Type: Application
    Filed: June 12, 2025
    Publication date: May 7, 2026
    Inventor: Kazuhiro KIMURA
  • Patent number: 12357613
    Abstract: The present invention addresses the problem of providing an inhibitor for retinochoroidal disorders, in particular, an inhibitor for retinochoroidal scar formation and retinochoroidal atrophy in an epiretinal, intraretinal or subretinal tissue. This problem can be solved by preparing an inhibitor for retinochoroidal disorders which comprises, as an active ingredient, (E)-4-(2-{3-[(1H-pyrazol-1-yl)methyl]-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene-2-yl}vinyl)benzoic acid, an ester thereof or a salt of the same. The inhibitor for retinochoroidal disorders can inhibit collagen atrophy of retinal pigment epithelium cells, fibroblasts, glial cells and the like and thus inhibit retinochoroidal disorders.
    Type: Grant
    Filed: July 10, 2023
    Date of Patent: July 15, 2025
    Assignee: YAMAGUCHI UNIVERSITY
    Inventor: Kazuhiro Kimura
  • Patent number: 12204603
    Abstract: In order to solve a conventional problem that it is not possible to manage partial content in a webpage as a block and execute processing on the block, a webpage processing apparatus includes: a block information storage unit in which one or more pieces of block information each having a block identifier for identifying a block, which is partial content in a webpage, and location identifying information for specifying a location of the block in the webpage are stored; a block processing unit that executes block processing, which is processing regarding a block specified with block information, using location identifying information contained in any one of the one or more pieces of block information; and a result output unit that outputs a block processing result, which is a result of the block processing. Accordingly, it is possible to manage a block, which is partial content in a webpage, and execute processing on the block.
    Type: Grant
    Filed: June 2, 2021
    Date of Patent: January 21, 2025
    Assignee: PLAID, INC.
    Inventors: Takahiro Tokunaga, Yuichi Yabu, Takami Yamada, Kazuhiro Kimura, Ryosuke Suzuki, Naoya Muto, Hirofumi Tanahashi, Minori Tokuda
  • Publication number: 20240180873
    Abstract: The present invention addresses the problem of providing an inhibitor for retinochoroidal disorders, in particular, an inhibitor for retinochoroidal scar formation and retinochoroidal atrophy in an epiretinal, intraretinal or subretinal tissue. This problem can be solved by preparing an inhibitor for retinochoroidal disorders which comprises, as an active ingredient, (E)-4-(2-{3-[(1H-pyrazol-1-yl)methyl]-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene-2-yl}vinyl)benzoic acid, an ester thereof or a salt of the same. The inhibitor for retinochoroidal disorders can inhibit collagen atrophy of retinal pigment epithelium cells, fibroblasts, glial cells and the like and thus inhibit retinochoroidal disorders.
    Type: Application
    Filed: July 10, 2023
    Publication date: June 6, 2024
    Applicant: YAMAGUCHI UNIVERSITY
    Inventor: Kazuhiro KIMURA
  • Patent number: 11730718
    Abstract: The present invention addresses the problem of providing an inhibitor for retinochoroidal disorders, in particular, an inhibitor for retinochoroidal scar formation and retinochoroidal atrophy in an epiretinal, intraretinal or subretinal tissue. This problem can be solved by preparing an inhibitor for retinochoroidal disorders which comprises, as an active ingredient, (E)-4-(2-{3-[(1H-pyrazol-1-yl)methyl]-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene-2-yl}vinyl)benzoic acid, an ester thereof or a salt of the same. The inhibitor for retinochoroidal disorders can inhibit collagen atrophy of retinal pigment epithelium cells, fibroblasts, glial cells and the like and thus inhibit retinochoroidal disorders.
    Type: Grant
    Filed: June 4, 2020
    Date of Patent: August 22, 2023
    Assignee: YAMAGUCHI UNIVERSITY
    Inventor: Kazuhiro Kimura
  • Publication number: 20230255937
    Abstract: The present invention addresses the problem of providing a novel therapeutic agent for keratoconjunctive disorders. As a means for solving the problem, a therapeutic agent for keratoconjunctive disorders which contains a RAR? agonist as an active ingredient is provided. The therapeutic agent exhibits an excellent ameliorating effect in a keratoconjunctive disorder model, and is therefore useful as a therapeutic agent for keratoconjunctive disorders such as corneal ulcer, corneal epithelial abrasion, keratitis, dry eye, conjunctivitis, chronic superficial keratitis, corneal erosion, persistent corneal disorders, superficial punctate keratopathy, corneal epithelial defects, conjunctival epithelial defects, keratoconjunctivitis sicca, superior limbic keratoconjunctivitis, filamentary keratoconjunctivitis, infectious keratitis, noninfectious keratitis, infectious conjunctivitis and noninfectious conjunctivitis.
    Type: Application
    Filed: September 7, 2022
    Publication date: August 17, 2023
    Inventor: Kazuhiro KIMURA
  • Publication number: 20230237118
    Abstract: In order to solve a conventional problem that it is not possible to manage partial content in a webpage as a block and execute processing on the block, a webpage processing apparatus 7 includes: a block information storage unit 711 in which one or more pieces of block information each having a block identifier for identifying a block, which is partial content in a webpage, and location identifying information for specifying a location of the block in the webpage are stored; a block processing unit 731 that executes block processing, which is processing regarding a block specified with block information, using location identifying information contained in any one of the one or more pieces of block information; and a result output unit 751 that outputs a block processing result, which is a result of the block processing. Accordingly, it is possible to manage a block, which is partial content in a webpage, and execute processing on the block.
    Type: Application
    Filed: June 2, 2021
    Publication date: July 27, 2023
    Inventors: Takahiro TOKUNAGA, Yuichi YABU, Takami YAMADA, Kazuhiro KIMURA, Ryosuke SUZUKI, Naoya MUTO, Hirofumi TANAHASHI, Minori TOKUDA
  • Patent number: 11471440
    Abstract: The present invention addresses the problem of providing a novel therapeutic agent for keratoconjunctive disorders. As a means for solving the problem, a therapeutic agent for keratoconjunctive disorders which contains a RAR? agonist as an active ingredient is provided. The therapeutic agent exhibits an excellent ameliorating effect in a keratoconjunctive disorder model, and is therefore useful as a therapeutic agent for keratoconjunctive disorders such as corneal ulcer, corneal epithelial abrasion, keratitis, dry eye, conjunctivitis, chronic superficial keratitis, corneal erosion, persistent corneal disorders, superficial punctate keratopathy, corneal epithelial defects, conjunctival epithelial defects, keratoconjunctivitis sicca, superior limbic keratoconjunctivitis, filamentary keratoconjunctivitis, infectious keratitis, noninfectious keratitis, infectious conjunctivitis and noninfectious conjunctivitis.
    Type: Grant
    Filed: December 2, 2019
    Date of Patent: October 18, 2022
    Assignee: YAMAGUCHI UNIVERSITY
    Inventor: Kazuhiro Kimura
  • Patent number: 11378526
    Abstract: A faulted condition determination method is designed to detect a chromium content and a nickel content in a predetermined boundary region proximate to a boundary between a high-strength ferrite steel and a weld material in a welded joint in which the high-strength ferrite steel and another steel are welded together using the weld material containing nickel and to thereby determine the faulted condition of the predetermined boundary region based on the chromium content and the nickel content. Accordingly, it is possible to appropriately determine the faulted condition of welding of a replacement part in which a high-strength ferrite steel and another steel are welded together using a nickel-based weld material.
    Type: Grant
    Filed: February 7, 2019
    Date of Patent: July 5, 2022
    Assignees: MITSUBISHI HEAVY INDUSTRIES, LTD., NATIONAL INSTITUTE FOR MATERIALS SCIENCE
    Inventors: Nobuhiko Saito, Nobuyoshi Komai, Yuichi Hirakawa, Hiroaki Fukushima, Kota Sawada, Kazuhiro Kimura, Kaoru Sekido
  • Publication number: 20210407865
    Abstract: According to one aspect of the technique, there is provided a method of manufacturing a semiconductor device, including: (a) heating a heat insulating plate in a substrate retainer to a processing temperature by an electromagnetic wave, and measuring a temperature change of the heat insulating plate by a non-contact type thermometer until the processing temperature; (b) heating a test object provided with a chip that does not transmit a detection light of the thermometer and accommodated in the substrate retainer to the processing temperature, and measuring a temperature change of the chip by the thermometer until the processing temperature; (c) acquiring a correlation between the temperature change of the heat insulating plate and that of the chip based on measurement results; and (d) controlling a heater to heat the substrate based on the correlation and the temperature of the heat insulating plate measured by the thermometer.
    Type: Application
    Filed: September 13, 2021
    Publication date: December 30, 2021
    Inventors: Kenji SHINOZAKI, Tetsuo YAMAMOTO, Yukitomo HIROCHI, Yoshihiko YANAGISAWA, Naoki HARA, Masaaki UENO, Hideto YAMAGUCHI, Hitoshi MURATA, Shuhei SAIDO, Kazuhiro KIMURA
  • Patent number: 11198935
    Abstract: A heating part of covering and heating a gas pipe includes: a thermal insulation portion disposed outside a heat generation body; an enclosure configured to enclose the thermal insulation portion and the heat generation body; a fastening part installed outside the enclose and configured to fasten one end portion and the other end portion of the enclosure in a state in which the one end portion and the other end portion of the enclosure adjoin each other; and a temperature sensing part disposed at the side of the gas pipe with respect to the enclosure at a position facing a surface of the gas pipe and formed in a plate shape with a major surface thereof oriented toward the gas pipe.
    Type: Grant
    Filed: September 22, 2016
    Date of Patent: December 14, 2021
    Assignee: KOKUSAI ELECTRIC CORPORATION
    Inventors: Shinobu Sugiura, Yosuke Kuwata, Tomoyasu Miyashita, Atsushi Umekawa, Kazuhiro Kimura, Akihiko Hiratsuka, Kaoru Kataoka, Ryosuke Arai
  • Publication number: 20210347642
    Abstract: A porous carbon material wherein a particle diameter is 10 ?m or more but 1 cm or less; wherein a bulk specific gravity is 0.20 g/cm3 or more; and wherein a mesopore volume is 0.10 cm3/g or more.
    Type: Application
    Filed: July 20, 2021
    Publication date: November 11, 2021
    Inventors: Hirofumi TAKEKUMA, Shinichiro YAMADA, Kazuhiro KIMURA, Takuhiro ISHII, Katsuya TANBA
  • Patent number: 11143233
    Abstract: A rolling bearing includes an inner ring, an outer ring, and a plurality of balls interposed between the inner ring and the outer ring. The inner ring and the outer ring are made of stainless steel. A raceway surface with which the ball is in rolling-contact in each of the inner ring and the outer ring and is a superfinished surface and a coating layer made of a solid lubricating film is formed on the superfinished surface.
    Type: Grant
    Filed: June 6, 2018
    Date of Patent: October 12, 2021
    Assignee: JTEKT CORPORATION
    Inventor: Kazuhiro Kimura
  • Patent number: 11078095
    Abstract: [Solution] Provided is a water purification agent suitable for use in an automated purification treatment device, when a wastewater purification treatment using a plant-derived water purification agent is performed with the automated purification treatment device. The water purification agent is a granulated product containing a mixture of a plant powder and a polymer coagulant.
    Type: Grant
    Filed: September 4, 2019
    Date of Patent: August 3, 2021
    Assignee: Dexerials Corporation
    Inventors: Kazuhiro Kimura, Koji Hirata
  • Patent number: 11022172
    Abstract: A rolling bearing device includes a rotary shaft; a housing; a pair of rolling bearings; an outer ring spacer; an elastic member provided in a bottom side of the housing, the bottom side of the housing being a second axial side of the housing, and the elastic member being configured to urge the rolling bearings, the outer ring spacer, and the rotary shaft toward a first axial side; and a retaining ring that is fitted into a circumferential groove provided on an inner periphery in the first axial side of the housing, the retaining ring being in axial contact with the outer ring of the rolling bearing located on the first axial side, and the retaining ring including at least three arc members arranged in a circumferential direction.
    Type: Grant
    Filed: March 2, 2020
    Date of Patent: June 1, 2021
    Assignee: JTEKT CORPORATION
    Inventors: Yui Tanaka, Kazuhiro Kimura, Masaaki Ohtsuki
  • Publication number: 20210143003
    Abstract: Methods for depositing on a surface of a substrate are disclosed. Exemplary methods include depositing a silicon oxide material using a cyclical deposition process, and reflowing the material during one or more of the step of depositing and a post-deposition anneal step. Structures including a layer of the material are also disclosed.
    Type: Application
    Filed: November 9, 2020
    Publication date: May 13, 2021
    Inventors: Hideaki Fukuda, Shinya Ueda, Kazuhiro Kimura
  • Publication number: 20210121442
    Abstract: The present invention addresses the problem of providing an inhibitor for retinochoroidal disorders, in particular, an inhibitor for retinochoroidal scar formation and retinochoroidal atrophy in an epiretinal, intraretinal or subretinal tissue. This problem can be solved by preparing an inhibitor for retinochoroidal disorders which comprises, as an active ingredient, (E)-4-(2-{3-[(1H-pyrazol-1-yl)methyl]-5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalene-2-yl}vinyl)benzoic acid, an ester thereof or a salt of the same. The inhibitor for retinochoroidal disorders can inhibit collagen atrophy of retinal pigment epithelium cells, fibroblasts, glial cells and the like and thus inhibit retinochoroidal disorders.
    Type: Application
    Filed: June 4, 2020
    Publication date: April 29, 2021
    Inventor: Kazuhiro KIMURA
  • Publication number: 20210115968
    Abstract: A rolling bearing includes an inner ring, an outer ring, and a plurality of balls interposed between the inner ring and the outer ring. The inner ring and the outer ring are made of stainless steel. A raceway surface with which the ball is in rolling-contact in each of the inner ring and the outer ring and is a superfinished surface and a coating layer made of a solid lubricating film is formed on the superfinished surface.
    Type: Application
    Filed: June 6, 2018
    Publication date: April 22, 2021
    Applicant: JTEKT CORPORATION
    Inventor: Kazuhiro KIMURA
  • Patent number: 10954142
    Abstract: Provided is a water-purifying agent that is excellent in water purifying performance, can be suitably used in an automated wastewater purification apparatus, and is formed of a granulated product including a mixture of a powder of Corchorus olitorius and a polymeric flocculant, wherein a median diameter of the granulated product is 250 micrometers or greater but 850 micrometers or less.
    Type: Grant
    Filed: March 8, 2016
    Date of Patent: March 23, 2021
    Assignee: DEXERIALS CORPORATION
    Inventors: Masayuki Nakamura, Ryu Shimada, Takanori Fujita, Kazuhiro Kimura, Masato Hasegawa
  • Publication number: 20200345695
    Abstract: The present invention addresses the problem of providing a novel therapeutic agent for keratoconjunctive disorders. As a means for solving the problem, a therapeutic agent for keratoconjunctive disorders which contains a RAR? agonist as an active ingredient is provided. The therapeutic agent exhibits an excellent ameliorating effect in a keratoconjunctive disorder model, and is therefore useful as a therapeutic agent for keratoconjunctive disorders such as corneal ulcer, corneal epithelial abrasion, keratitis, dry eye, conjunctivitis, chronic superficial keratitis, corneal erosion, persistent corneal disorders, superficial punctate keratopathy, corneal epithelial defects, conjunctival epithelial defects, keratoconjunctivitis sicca, superior limbic keratoconjunctivitis, filamentary keratoconjunctivitis, infectious keratitis, noninfectious keratitis, infectious conjunctivitis and noninfectious conjunctivitis.
    Type: Application
    Filed: December 2, 2019
    Publication date: November 5, 2020
    Inventor: Kazuhiro KIMURA