Patents by Inventor Kazuhiro Nagaike

Kazuhiro Nagaike has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • BIFUNCTIONAL WATER-SOLUBLE POLYMER DERIVATIVE AND COMPLEX CONTAINING IT
    Publication number: 20020025312
    Abstract: A bifunctional water-soluble polymer derivative having a moiety reactive with an amino group and a thiol group moiety or a latent thiol group moiety.
    Type: Application
    Filed: September 16, 1998
    Publication date: February 28, 2002
    Inventors: TOSHIAKI TAGAWA, TSUTOMU SUZUKI, NOBUHISA YADA, KAZUHIRO NAGAIKE, YOKO HIRAKAWA, SAIKO HOSOKAWA
  • Human monoclonal antibody specifically binding to surface antigen of cancer cell membrane
    Patent number: 6139869
    Abstract: A human monoclonal antibody specifically binding to a surface antigen of cancer cell membrane, an isolated DNA encoding the antibody, and a hybridoma producing the antibody. An anti-cancer formulation comprising the monoclonal antibody bonded to the surface of a liposome enclosing an anti-cancer agent or toxin is also provided.
    Type: Grant
    Filed: May 25, 1995
    Date of Patent: October 31, 2000
    Assignee: Mitsubishi Kasei Corporation
    Inventors: Saiko Hosokawa, Toshiaki Tagawa, Yoko Hirakawa, Norihiko Ito, Kazuhiro Nagaike
  • Human monoclonal antibody specifically binding to surface antigen of cancer cell membrane
    Patent number: 5990287
    Abstract: A human monoclonal antibody specifically binding to a surface antigen of cancer cell membrane, an isolated DNA encoding the antibody, and a hybridoma producing the antibody. An anti-cancer formulation comprising the monoclonal antibody bonded to the surface of a liposome enclosing an anti-cancer agent or toxin is also provided.
    Type: Grant
    Filed: February 2, 1998
    Date of Patent: November 23, 1999
    Assignee: Mitsubishi Chemical Corporation
    Inventors: Saiko Hosokawa, Toshiaki Tagawa, Yoko Hirakawa, Norihiko Ito, Kazuhiro Nagaike
  • Human monoclonal antibody specifically binding to surface antigen of cancer cell membrane
    Patent number: 5990297
    Abstract: A human monoclonal antibody specifically binding to a surface antigen of cancer cell membrane, an isolated DNA encoding the antibody, and a hybridoma producing the antibody. An anti-cancer formulation comprising the monoclonal antibody bonded to the surface of a liposome enclosing an anti-cancer agent or toxin is also provided.
    Type: Grant
    Filed: January 28, 1998
    Date of Patent: November 23, 1999
    Assignee: Mitsubishi Chemical Corporation
    Inventors: Saiko Hosokawa, Toshiaki Tagawa, Yoko Hirakawa, Norihiko Ito, Kazuhiro Nagaike
  • Human monoclonal antibody specifically binding to surface antigen of cancer cell membrane
    Patent number: 5837845
    Abstract: A human monoclonal antibody specifically binding to a surface antigen of cancer cell membrane, an isolated DNA encoding the antibody, and a hybridoma producing the antibody. An anti-cancer formulation comprising the monoclonal antibody bonded to the surface of a liposome enclosing an anti-cancer agent or toxin is also provided.
    Type: Grant
    Filed: May 25, 1995
    Date of Patent: November 17, 1998
    Assignee: Mitsubishi Chemical Corporation
    Inventors: Saiko Hosokawa, Toshiaki Tagawa, Yoko Hirakawa, Norihiko Ito, Kazuhiro Nagaike
  • Human monoclonal antibody specifically binding to surface antigen of cancer cell membrane
    Patent number: 5767246
    Abstract: A human monoclonal antibody specifically binding to a surface antigen of cancer cell membrane, an isolated DNA encoding the antibody, and a hybridoma producing the antibody. An anti-cancer formulation comprising the monoclonal antibody bonded to the surface of a liposome enclosing an anti-cancer agent or toxin is also provided.
    Type: Grant
    Filed: December 20, 1994
    Date of Patent: June 16, 1998
    Assignee: Mitsubishi Chemical Corporation
    Inventors: Saiko Hosokawa, Toshiaki Tagawa, Yoko Hirakawa, Norihiko Ito, Kazuhiro Nagaike
  • Phospholipid derivative and liposome containing it
    Patent number: 5686101
    Abstract: A phospholipid derivative of the following formula (I): ##STR1## wherein A is a residue of a phospholipid having a phosphatidylethanolamine moiety, and B is a linking group having a polyalkylene glycol moiety.
    Type: Grant
    Filed: January 24, 1996
    Date of Patent: November 11, 1997
    Assignee: Mitsubishi Chemical Corporation
    Inventors: Toshiaki Tagawa, Kaoru Awane, Kazuhiro Nagaike
  • Phospholipid derivatized with PEG bifunctional linker and liposome containing it
    Patent number: 5556948
    Abstract: A phospholipid derivative of the following formula (I): ##STR1## wherein A is a residue of a phospholipid having a phosphatidylethanolamine moiety, and B is a linking group having a polyalkylene glycol moiety.
    Type: Grant
    Filed: January 19, 1994
    Date of Patent: September 17, 1996
    Assignee: Mitsubishi Chemical Corporation
    Inventors: Toshiaki Tagawa, Kaoru Awane, Kazuhiro Nagaike
  • Drug-containing protein-bonded liposome
    Patent number: 5264221
    Abstract: A drug-containing protein-bonded liposome comprising a liposome containing a drug and having maleimide residues on its surface, and a protein and residues of a compound having a polyalkylene glycol moiety, bonded via respective thiol groups to the maleimide residues.
    Type: Grant
    Filed: May 22, 1992
    Date of Patent: November 23, 1993
    Assignee: Mitsubishi Kasei Corporation
    Inventors: Toshiaki Tagawa, Saiko Hosokawa, Kazuhiro Nagaike