Abstract: A lighting device includes an indoor lamp (11), being provided in the cabin of a railroad vehicle (1) in order to wholly irradiate the inside of the cabin over the longitudinal direction of the vehicle, a vehicle body power supply (20), supplying electric power to the indoor lamp (11), and a storage battery (30), being charged with a voltage applied by the vehicle body power supply (20). The indoor lamp (11) includes a general lamp light source (12) and a standby lamp light source (13), being lighted at an illuminance lower than that at which the general lamp light source (12) is lighted, and the general lamp source (12) being supplied with electric power from the vehicle body power supply (20) not through the storage battery (30), while the standby lamp light source (13) being supplied with electric power from the vehicle body power supply (20) through the storage battery (30).

Abstract: The casing of an electronic control device includes a casing-side contact surface in contact with the end of a printed-circuit board. A cover includes a cover-side contact surface holding the end of the printed-circuit board together with the casing-side contact surface by being in contact with the end of the printed-circuit board. In the printed-circuit board, a held portion held between the casing-side contact surface and the cover-side contact surface is provided with a through-hole via.

Abstract: Provided is a filling liquid (161) for filling a balloon (170) for a method for occluding a tubular organ, including a microcapsule (162) in which a balloon-dissolving substance that dissolves the balloon (170) is encapsulated, wherein the microcapsule is destroyable by an ultrasonic beam; and a liquid that is harmless in the tubular organ and does not dissolve the balloon. Further provided is a method for terminating a tubular organ occlusion including a step of applying an ultrasonic beam to a balloon (170) that is filled with the filling liquid (161) and occludes a tubular organ, thereby breaking the balloon (170) as a result.

Abstract: The casing of an electronic control device includes a casing-side contact surface in contact with the end of a printed-circuit board. A cover includes a cover-side contact surface holding the end of the printed-circuit board together with the casing-side contact surface by being in contact with the end of the printed-circuit board. In the printed-circuit board, a held portion held between the casing-side contact surface and the cover-side contact surface is provided with a through-hole via.

Abstract: Provided is a power supply adjustment system including: an electronic load whose load voltage is variable; a power supply board that supplies the electronic load with current; and an information processing apparatus that controls the load voltage of the electronic load and the output current of the power supply board to the electronic load on the basis of a current value in the load voltage, in which the information processing apparatus includes a control unit that sets a plurality of load voltages in a predetermined range as the load voltage of the electronic load and sets a correction current value for adjusting the output current to a preset target current value for each of the plurality of load voltages.

Abstract: A lighting device includes an indoor lamp (11), being provided in the cabin of a railroad vehicle (1) in order to wholly irradiate the inside of the cabin over the longitudinal direction of the vehicle, a vehicle body power supply (20), supplying electric power to the indoor lamp (11), and a storage battery (30), being charged with a voltage applied by the vehicle body power supply (20). The indoor lamp (11) includes a general lamp light source (12) and a standby lamp light source (13), being lighted at an illuminance lower than that at which the general lamp light source (12) is lighted, and the general lamp source (12) being supplied with electric power from the vehicle body power supply (20) not through the storage battery (30), while the standby lamp light source (13) being supplied with electric power from the vehicle body power supply (20) through the storage battery (30).

Abstract: Provided is a theranostic bubble preparation which makes it possible to diagnose and treat a tissue of interest by the irradiation with ultrasound such as diagnostic ultrasound and low-intensity therapeutic ultrasound. The theranostic bubble preparation comprises: a coating film comprising a lipid; and a gas enclosed in an inner cavity formed in the coating film. The coating film comprises an anionic lipid made from distearoylphosphatidylcholine (DSPC), distearoylphosphatidylglycerol (DSPG) and 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (DSPE-PEG2000). The gas and the mixed gas comprises perfluoropropane or perfluorobutane.

Abstract: Provided is a power supply adjustment system including: an electronic load whose load voltage is variable; a power supply board that supplies the electronic load with current; and an information processing apparatus that controls the load voltage of the electronic load and the output current of the power supply board to the electronic load on the basis of a current value in the load voltage, in which the information processing apparatus includes a control unit that sets a plurality of load voltages in a predetermined range as the load voltage of the electronic load and sets a correction current value for adjusting the output current to a preset target current value for each of the plurality of load voltages.

Abstract: A power supply system (120) according to an embodiment of the present invention includes a first power supply device (121), a second power supply device (122), and an addition circuit (123). The first power supply device (121) includes a first driving circuit that outputs a first direct current from a first power supply input and a first control circuit that controls the first driving circuit. The second power supply device (122) includes a second driving circuit that outputs a second direct current from a second power supply input and a second control circuit that monitors the first driving circuit and controls the second driving circuit. The addition circuit (123) is connected to an output terminal of each of the first and second power supply devices (121, 122) and outputs a third direct current that is a value obtained by adding the first and second direct currents to a load device (on-board illumination device (110)).

Abstract: A power supply system (120) according to an embodiment of the present invention includes a first power supply device (121), a second power supply device (122), and an addition circuit (123). The first power supply device (121) includes a first driving circuit that outputs a first direct current from a first power supply input and a first control circuit that controls the first driving circuit. The second power supply device (122) includes a second driving circuit that outputs a second direct current from a second power supply input and a second control circuit that monitors the first driving circuit and controls the second driving circuit. The addition circuit (123) is connected to an output terminal of each of the first and second power supply devices (121, 122) and outputs a third direct current that is a value obtained by adding the first and second direct currents to a load device (on-board illumination device (110)).

Abstract: Provided is a theranostic bubble preparation which makes it possible to diagnose and treat a tissue of interest by the irradiation with ultrasound such as diagnostic ultrasound and low-intensity therapeutic ultrasound. The theranostic bubble preparation comprises: a coating film comprising a lipid; and a gas enclosed in an inner cavity formed in the coating film. The coating film comprises an anionic lipid made from distearoylphosphatidylcholine (DSPC), distearoylphosphatidylglycerol (DSPG) and 1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[methoxy(polyethylene glycol)-2000] (DSPE-PEG2000). The gas and the mixed gas comprises perfluoropropane or perfluorobutane.

Abstract: To provide a technology for introducing a PMO with remarkably enhanced cell permeability, leading to significantly enhanced introduction efficiency to thereby provide a therapeutic drug that dramatically ameliorates a medical condition of DMD. Also provided is a therapeutic drug for Duchenne muscular dystrophy, including as an active ingredient a Bubble liposome having a specific morpholino oligomer (PMO) bound to a surface thereof, in which the PMO is introduced into a muscle fiber (muscle cell) of a muscle tissue with high efficiency by administration of the therapeutic drug into the muscle tissue or into a blood vessel followed by ultrasound irradiation to the muscle tissue transcutaneously.

Abstract: To provide a technology for introducing a PMO with remarkably enhanced cell permeability, leading to significantly enhanced introduction efficiency to thereby provide a therapeutic drug that dramatically ameliorates a medical condition of DMD. Also provided is a therapeutic drug for Duchenne muscular dystrophy, including as an active ingredient a Bubble liposome having a specific morpholino oligomer (PMO) bound to a surface thereof, in which the PMO is introduced into a muscle fiber (muscle cell) of a muscle tissue with high efficiency by administration of the therapeutic drug into the muscle tissue or into a blood vessel followed by ultrasound irradiation to the muscle tissue transcutaneously.

Abstract: A sliding bearing comprises a shaft hole for rotatably supporting a shaft that is inserted thereinto, an inner circumferential surface on which the shaft slides, and plural linearly oblique grooves. The grooves extend in a direction crossing a circumferential direction of the sliding bearing and are formed on the inner circumferential surface at intervals, and the grooves are provided with a lubricant. The oblique grooves have an oblique angle in a range of 10° to 60° with respect to a direction perpendicular to the circumferential direction and have a width B in a range of 0.5 to 5 mm in the circumferential direction. The adjacent grooves have a land with a surface as a sliding surface therebetween, and the sliding surface has a width A in a range of 1 to 7 mm in the circumferential direction. A ratio A/B of the width A of the sliding surface of the land to the width B of the groove is in a range of 0.5 to 5.0.

Abstract: A heat dissipating structure of a print circuit board to improve heat-dissipation efficiency for mounted electronic components while retaining required soldering strength is disclosed. The heat dissipation structure of a print circuit board comprising a stack of multiple layers including a mounting surface layer on which electronic components including heat generating components are soldered. On both sides of the print circuit board, inner vias bore surface layers but inner layers are not bored. Core vias bore the inner layers in the print circuit board but the surface layers are not bored. The inner vias and the core vias are positioned at the predetermined distance over the layer surface. Heat from heat generating components is conducted through the inner vias on surface layers and the core vias inside the circuit board to the outside, high efficiency of the heat-dissipation is achieved.

Abstract: A method for efficiently transferring a gene to a target cell is provided. A method of transferring a gene to a target cell, including adding or administering a positively charged complex (A) composed of the gene and a cationic substance and gas-filled microparticles (B) to a target cell-containing composition or a living body and then exposing the target cell-containing composition or the living body to a low-frequency ultrasound.

Abstract: A heat dissipating structure of a print circuit board to improve heat-dissipation efficiency for mounted electronic components while retaining required soldering strength is disclosed. The heat dissipation structure of a print circuit board comprising a stack of multiple layers including a mounting surface layer on which electronic components including heat generating components are soldered. On both sides of the print circuit board, inner vias bore surface layers but inner layers are not bored. Core vias bore the inner layers in the print circuit board but the surface layers are not bored. The inner vias and the core vias are positioned at the predetermined distance over the layer surface. Heat from heat generating components is conducted through the inner vias on surface layers and the core vias inside the circuit board to the outside, high efficiency of the heat-dissipation is achieved.

Abstract: Gas-filled liposomes that are useful for ultrasonography and ultrasound therapy are provided. A method of producing the gas-filled liposomes, including filling the void space in a sealed container containing a liposome suspension in a volume amounting to 20 to 80% of the inner capacity thereof with a fluoride gas or a nitrogen gas, and subjecting the container to an ultrasonication.

Abstract: A sliding bearing comprises a shaft hole for rotatably supporting a shaft that is inserted thereinto, an inner circumferential surface on which the shaft slides, and plural linearly oblique grooves. The grooves extend in a direction crossing a circumferential direction of the sliding bearing and are formed on the inner circumferential surface at intervals, and the grooves are provided with a lubricant. The oblique grooves have an oblique angle in a range of 10° to 60° with respect to a direction perpendicular to the circumferential direction and have a width B in a range of 0.5 to 5 mm in the circumferential direction. The adjacent grooves have a land with a surface as a sliding surface therebetween, and the sliding surface has a width A in a range of 1 to 7 mm in the circumferential direction. A ratio A/B of the width A of the sliding surface of the land to the width B of the groove is in a range of 0.5 to 5.0.

Abstract: A sliding bearing which is suitable for and durable in the use under high load of sliding in rocking motion, and the structure of bearing is not complicated so as to facilitate the manufacturing. The alloy used for making the bearing is composed of iron-based sintered alloy having quenched structure, and the bearing surface is provided with inclined grooves of an inclination angle of 10 to 40° relative to the direction perpendicular to the sliding direction and a width of 2 to 8 mm and the area of inclined grooves is 50% or less of the total inner bearing surface and an imaginary line perpendicular to the sliding direction crosses both the inclined groove and the bearing surface at any position of the inner surface of bearing. When the bearing is used, at least the inclined grooves are impregnated with a lubricant.