Abstract: An iontophoresis system comprises a power supply apparatus having a chargeable battery, a positive output terminal, a negative output terminal and a positive charge terminal, and a preparation having input terminals connected to output terminals of the power supply apparatus. The negative output terminal of the power supply apparatus also serves as a negative charge terminal for charging the battery. During charging, the preparation is removed, and terminals of a charger are connected to terminals of the power supply apparatus, respectively. The power supply apparatus comprises a power supply monitoring portion which gives a warning when a battery voltage becomes a predetermined value or lower and a control portion for controlling a power supply state from the output terminal.

Abstract: An iontophoresis system comprises a power supply apparatus having a chargeable battery, a positive output terminal, a negative output terminal and a positive charge terminal, and a preparation having input terminals connected to output terminals of the power supply apparatus. The negative output terminal of the power supply apparatus also serves as a negative charge terminal for charging the battery. During charging, the preparation is removed, and terminals of a charger are connected to terminals of the power supply apparatus, respectively. The power supply apparatus comprises a power supply monitoring portion which gives a warning when a battery voltage becomes a predetermined value or lower and a control portion for controlling a power supply state from the output terminal.

Abstract: A field-effect transistor includes a channel layer that is formed on a predetermined semiconductor layer and has an impurity concentration varying from a low value to a high value, and a source region and a drain region each having a bottom face above the predetermined semiconductor layer.

Abstract: Compositions for reducing an adverse skin reaction caused by a skin-irritating agent or skin sensitizing agent by treatment with a disaccharide and a metal ion, as well as methods for reducing an adverse skin reaction caused by a skin-irritating or skin-sensitizing agent, and methods for treating an inflammatory response to at least one inflammatory agent, by application of a disaccharide and/or metal ion composition.

Abstract: A semiconductor device includes a gate electrode on a semiconductor substrate, a source electrode and a drain electrode that are provided on the semiconductor substrate, the gate electrode being interposed between the source electrode and the drain electrode, an insulating layer covering the gate electrode, and a source wall that extends from the source electrode and passes over the gate electrode, an end surface of the source wall being interposed between the gate electrode and the drain electrode and being located in a position lower than a top surface of the gate electrode.

Abstract: A transdermal or transmucosal drug delivery device excellent in terms of drug permeability and skin irritability and capable of reducing power consumption, is disclosed. An output control circuit (4) of an energization pattern controller (1) supplies a combined energization of pulse depolarized type energization and at least one of direct current type energization and pulse energization between an anode-side device (5) and a cathode-side device (6) of iontophoresis. The details of combination of energization in the output control circuit (4) is determined based on external setting of the energization pattern controller (1) or internal storage information.

Abstract: The present invention provides an iontophoresis device allowing effective and continuous absorption for a long period. The iontophoresis device comprises the first electrode structure (100a) and the second electrode structure (110a) each having a hydrophilic conductive layer (102a, 112a) containing active ingredient and an electrode member (101a, 111a), and a power supply (120a) having polarity inverting means for switching over a current direction between the two electrode structures, wherein at least one of the first and the second electrode structures contains chloride ions and before administration, a chloride-ion content (P mg) is within a range satisfying the following equation: 1.0×(I×T×0.022)≦P wherein T represents a polarity inverting time (min) until polarity is inverted after energization in a certain direction and I represents an average current (mA).

Abstract: A transdermal or transmucosal drug delivery device excellent in terms of drug permeability and skin irritability and capable of reducing power consumption, is disclosed. An output control circuit (4) of an energization pattern controller (1) supplies a combined energization of pulse depolarized type energization and at least one of direct current type energization and pulse energization between an anode-side device (5) and a cathode-side device (6) of iontophoresis. The details of combination of energization in the output control circuit (4) is determined based on external setting of the energization pattern controller (1) or internal storage information.

Abstract: A handling-convenient device for iontophoresis, which can supply spotted regions suffering from disease with a proper quantity of current at the same time. The device for iontophoresis includes a power source apparatus having a plurality of output terminals outputting currents of predetermined values adjusted by a plurality of current control circuits, respectively, and a plurality of connecting cords, each cord being connected with one of the output terminals of the power source apparatus at one end thereof and being connected with an electrode structure at the other end. The connecting cords are attached with the power source apparatus in a mutually attachable/detachable fashion via connection terminals. The power source apparatus has an LED located thereon to notify of the energization status of the device and a power switch externally located thereon to control starts and stops of the apparatus.

Abstract: It is the object of the present invention to provide an iontophoresis device structure which has excellent contouring ability at its site of attachment, has very high safety, is of high quality with high product yields, and can be produced with fewer production steps to improve working efficiency and increase productivity to allow mass production at low cost. The iontophoresis device structure of the present invention has a construction provided with a cup-shaped support including a concave part, at least one electrification hole formed in the concave part, an electrode layer laid on the flat part of the rim of the concave part, and an electrolyte layer or drug-holding layer fitted into the concave part.

Abstract: In a compound semiconductor device constituting a field effect transistor having a buried p region 3, a channel region 4 is formed thin and highly doped by n-type impurity, and the buried p region 3 is formed shallowly and highly doped by p-type impurity to compensate the highly doped channel region 4. In order to prevent a leakage current between the highly doped buried p region 3 and a gate electrode 5, a low concentration p-type impurity region 2 is formed on both sides of the highly doped buried p region 3 to thus prevent a current flow via a portion other than a channel region. Accordingly, there can be provided the compound semiconductor device including an FET which is able to suppress both the deterioration in the pinch-off characteristic and the leakage current between neighboring elements due to p-type impurity conduction other than a channel in an FET which has a high concentration and thin active layer, while suppressing the short channel effect.

Abstract: A bio-stimulating device including a signal controller unit for outputting at least a high frequency digital signal and a low frequency digital signal, a coil unit for changing the voltage of the digital signals input thereto from the control unit and having a first voltage changing function for high frequency digital signals and a second voltage changing function for low frequency digital signals, and an electrode unit including at least one electrode to be attached to a body wherein different kinds of electric pulses having different frequencies from each other can be generated, the size minimized, and energy saved.

Abstract: A process for production of isobutylene by dehydration reaction of t-butyl alcohol or its aqueous solution is provided wherein the dehydration reaction is carried out in gaseous phase on fixed-bed type silica-alumina catalyst with adding non-reactive gas and/or water vapor to feed gas or reaction gas and/or with diluting at least a part of the catalyst with a carrier.

Abstract: A process for producing methacrylic acid which comprises reacting methacrylic acid and isobutylene in the presence of a sulfonic acid group-containing ion exchange resin by a continuous process while controlling the reaction at a reaction temperature of -20.degree. C. to +20.degree. C. so as to fulfil the following relation:y<100-50xwherein x is the ratio of the total molar number of isobutylene and its reaction products to the total molar number of methacrylic acid and its reaction products and y is conversion (%) of isobutylene, followed by degassing the unreacted isobutylene, distilling off the low boiling substances by distillation under reduced pressure, and then sending the remainder to a t-butyl methacrylate purifying tower where a product of high purity is obtained from the distillate side and unreacted methacrylic acid is withdrawn from the tower bottom side and circulated into the reaction step.

Abstract: Highly purified isobutylene, up to 99.9% pure, is obtained by treating a reaction mixture such as that recovered from an isobutylene-containing hydrocarbon mixture also containing an aqueous solution of an aliphatic carboxylic acid having 1 to 6 carbon atoms that has been reacted in an acidic ion exchanger and from which the unreacted hydrocarbons have been removed. The operative ingredients of the treated mixture are tertiary butyl alcohol, secondary butyl alcohol and their esters of the carboxylic acid employed. When treated with an acidic ion exchanger the carboxylic acid is first formed which inhibits the secondary butyl alcohol and secondary butyl ester of the acid from decomposing and high purity isobutylene is recovered therefrom by conventional distillation.