Abstract: An optical head includes a light-emitting substrate that emits light, a lens that focuses the light emitted from the light-emitting substrate, a holder that hold the light-emitting substrate and the lens, and a drive circuit that includes an electric element fixed to at least one of the lens and the holder and drives the light-emitting substrate.

Abstract: An optical head includes a light-emitting board that emits light, an attachment base that has a surface to which the light-emitting board is attached by an adhesive and a groove which is provided in the surface and extends to a portion below the light-emitting board, and a lens to condense the light emitted from the light-emitting board.

Abstract: An optical head includes a light-emitting element to emit light, a substrate to which the light-emitting element is fixed, a heat radiation member to which the substrate is fixed, a filling member filled between the substrate and the heat radiation member, and a lens to focus the light emitted from the light-emitting element.

Abstract: The present invention provides a method of improving the efficiency of establishment of induced pluripotent stem (iPS) cells, comprising inhibiting the p53 function in the step of somatic cell nuclear reprogramming. The inhibition of p53 function is achieved by bringing a substance selected from the group consisting of (1) chemical inhibitors of p53, (2) dominant negative mutants of p53 and nucleic acids that encode the same, (3) siRNAs and shRNAs against p53 and DNAs that encode the same, and (4) p53 pathway inhibitors, into contact with a somatic cell, and the like. The present invention also provides an agent for improving the efficiency of establishment of iPS cells, the agent comprising an inhibitor of p53 function, particularly (1) chemical inhibitors of p53, (2) dominant negative mutants of p53 and nucleic acids that encode the same, (3) siRNAs and shRNAs against p53 and DNAs that encode the same, and (4) p53 pathway inhibitors.

Abstract: An optical head includes a light-emitting board which emits light, an attachment base which includes a first opening formed in an area overlapping the light-emitting board, a second opening formed in an area different from the area overlapping the light-emitting board and a through-hole to connect the first opening and the second opening, and to which the light-emitting board is fixed, and a lens to condense the light emitted from the light-emitting board to a photoreceptor.

Abstract: The present invention provides a method of producing induced pluripotent stem (iPS) cells, comprising bringing a nuclear reprogramming substance into contact with dental pulp stem cells. By using dental pulp stem cells as a source of somatic cells, the efficiency of establishment of human iPS cells by transfer of 3 or 4 factors can be improved dramatically. Additionally, dental pulp stem cells are easily available because they can be isolated and prepared from extracted wisdom teeth and teeth extracted because of periodontal disease and the like, so that they can be used widely as a source of somatic cells for iPS cell banks.

Abstract: For efficient proliferation of pluripotent stem cells in a system free from any animal-derived material such as feeder cells or serum, the present invention provides a method for proliferation of pluripotent stem cells, which comprises culturing the pluripotent stem cells in a medium free from both feeder cells and serum in a system containing laminin-5.

Abstract: It is an object of the present invention to provide a method for efficiently preparing blood cells, such as mature megakaryocytes and platelets, from iPS cells in an in vitro culture system. The present invention provides a sac-like structure enclosing hematopoietic progenitor cells, which is obtained by inoculating iPS cells onto feeder cells and then culturing the iPS cells under conditions suitable for inducing the differentiation of hematopoietic progenitor cells. Moreover, the present invention also provides a method for producing various types of blood cells, which comprises culturing hematopoietic progenitor cells enclosed in the sac-like structure under conditions suitable for inducing the differentiation of blood cells. Furthermore, the present invention also provides a method for producing various types of blood cells, particularly megakaryocytes and platelets, without involving the sac-like structure.

Abstract: As a light beam of a scanning optical system unit is adjusted in the state where the scanning optical system unit is assembled, its adjustment work and the assembly work of the scanning optical system are prevented from being useless. Thus, a scanning optical system adjusting device which can adjust the scanning optical system quickly and at a low cost is to be provided. A scanning optical system adjusting device according to the invention includes a static angle control unit configured to maintain a rotation angle of a rotary polygon mirror in the assembly unit of the scanning optical system at a predetermined angle and make the rotary polygon mirror static there, and a light beam parameter measuring unit configured to measure a predetermined parameter of a light beam reflected by the rotary polygon mirror maintained at the predetermined angle by the static angle control unit.

Abstract: High-performance magnets are obtained by: housing metal evaporating materials (v) containing at least one of Dy and Tb and sintered magnets (S) inside a processing box; disposing the processing box inside a vacuum chamber; thereafter, heating the processing box to a predetermined temperature in a vacuum atmosphere to thereby evaporate the metal evaporating materials and cause them to be adhered to the sintered magnets. The metal atoms of the adhered Dy or Tb are diffused into grain boundaries and/or grain boundary phases of the sintered magnets. A method of manufacturing a permanent magnet is provided in which, even if the sintered magnets and the metal evaporating materials are disposed in close proximity to each other, the squareness of demagnetization curve is not impaired and in which high feasibility of mass production can be attained. While the metal evaporating materials are being evaporated, an inert gas is introduced into the processing chamber in which the sintered magnets are disposed.

Abstract: In a laser exposure device according to the present invention, a positioning pin, which is formed in a lens holder supporting a lens system, is inserted through an elongated hole for restriction of a board holder supporting a laser diode. An eccentric cam is inserted into an elongated hole for rotation movement formed in a board holder and a circular hole for rotation movement which is formed in the lens holder and which faces the elongated hole for rotation movement. An eccentric cam is inserted into an elongated hole for slide movement formed in the board holder and a circular hole for slide movement which is formed in the lens holder and which faces the elongated hole for slide movement. The eccentric cams are rotated to relatively move the board holder and lens holder with respect to each other to thereby establish alignment between the optical axes of the laser diode and lens system.

Abstract: The present invention relates to a nuclear reprogramming factor having an action of reprogramming a differentiated somatic cell to derive an induced pluripotent stem (iPS) cell. The present invention also relates to the aforementioned iPS cells, methods of generating and maintaining iPS cells, and methods of using iPS cells, including screening and testing methods as well as methods of stem cell therapy. The present invention also relates to somatic cells derived by inducing differentiation of the aforementioned iPS cells.

Abstract: In a laser exposure device according to the present invention, a positioning pin, which is formed in a lens holder supporting a lens system, is inserted through an elongated hole for restriction of a board holder supporting a laser diode. An eccentric cam is inserted into an elongated hole for rotation movement formed in a board holder and a circular hole for rotation movement which is formed in the lens holder and which faces the elongated hole for rotation movement. An eccentric cam is inserted into an elongated hole for slide movement formed in the board holder and a circular hole for slide movement which is formed in the lens holder and which faces the elongated hole for slide movement. The eccentric cams are rotated to relatively move the board holder and lens holder with respect to each other to thereby establish alignment between the optical axes of the laser diode and lens system.

Abstract: The present invention relates to a nuclear reprogramming factor having an action of reprogramming a differentiated somatic cell to derive an induced pluripotent stem (iPS) cell. The present invention also relates to the aforementioned iPS cells, methods of generating and maintaining iPS cells, and methods of using iPS cells, including screening and testing methods as well as methods of stem cell therapy. The present invention also relates to somatic cells derived by inducing differentiation of the aforementioned iPS cells.

Abstract: As a light beam of a scanning optical system unit is adjusted in the state where the scanning optical system unit is assembled, its adjustment work and the assembly work of the scanning optical system are prevented from being useless. Thus, a scanning optical system adjusting device which can adjust the scanning optical system quickly and at a low cost is to be provided. A scanning optical system adjusting device according to the invention includes a static angle control unit configured to maintain a rotation angle of a rotary polygon mirror in the assembly unit of the scanning optical system at a predetermined angle and make the rotary polygon mirror static there, and a light beam parameter measuring unit configured to measure a predetermined parameter of a light beam reflected by the rotary polygon mirror maintained at the predetermined angle by the static angle control unit.

Abstract: A data retrieval system and method includes a data server, a client terminal, and a web server. The client terminal performs a data retrieval operation. The web server handles data processed between the data server and the client terminal. The client terminal has a socket communications program for communicating with the web server without using the web browser of the web server. The web server communicates with the data server and sends data received from the data server back to the client terminal, in accordance with a request for data retrieval sent from the socket communications program of the client terminal.

Abstract: A liquid crystal display panel includes a moving image display area in which the pixel portions are arranged in a matrix shape and a pictograph display area in which the pixel portions are formed in a fixed pictograph shape. Moreover, first protective elements are inserted between the respective pixel portions in the moving image display area and a drive circuit for the pixel portions and are arranged in an outer periphery of the moving image display area. Second protective elements are inserted between the respective pixel portions in the pictogram display area and a drive circuit for the pixel portions and arranged in an outer periphery of the pictogram display area.

Abstract: In a laser exposure device according to the present invention, a positioning pin, which is formed in a lens holder supporting a lens system, is inserted through an elongated hole for restriction of a board holder supporting a laser diode. An eccentric cam is inserted into an elongated hole for rotation movement formed in a board holder and a circular hole for rotation movement which is formed in the lens holder and which faces the elongated hole for rotation movement. An eccentric cam is inserted into an elongated hole for slide movement formed in the board holder and a circular hole for slide movement which is formed in the lens holder and which faces the elongated hole for slide movement. The eccentric cams are rotated to relatively move the board holder and lens holder with respect to each other to thereby establish alignment between the optical axes of the laser diode and lens system.

Abstract: A liquid crystal display has a first substrate formed with a picture character pixel electrode for displaying a picture character represented by a fixed pattern, a second substrate formed with a common electrode opposite to the picture character pixel electrode, and a liquid crystal layer sandwiched between the first substrate and the second substrate. The picture character pixel electrode is formed on an interlayer insulating film, and is connected to a picture character signal electrode formed below the interlayer insulating film through a plurality of contact holes formed through the interlayer insulating film.

Abstract: The device has a frame body (12) that has a substantial C-shape in cross section and is mounted on the body of a user, a strip-shaped display panel (22) disposed along the peripheral surface of the frame body (12), and a driver IC (15) for driving the display panel (22), wherein the display panel (22) and the driver IC are provided to different flexible substrates (21A, 21B), and the flexible substrates (21A, 21B) are disposed along the peripheral surface of the frame body (12) without being superposed on each other.