Abstract: Provided are engineered cells fused with platelet membrane vesicles and capable of specifically targeting a subendothelial site of vascular injury. Also provided are methods of generating a modified cell or extracellular vesicle fused with platelet membrane vesicles or fragments thereof. Further provided are methods for using these engineered cells and vesicles for the treatment of injured tissue accompanied by vascular injury by engraftment with modified cells fused with platelet membrane vesicles. Cells fused with the platelet vesicles can be engineered stem cells such as cardiac or mesenchymal stem cells; the extracellular vesicles fused with the platelet vesicles can be exosomes such as exosomes derived from cardiac or mesenchymal stem cells. The use of the platelet vesicles for targeting sites of vascular injury may also be usefully applied to engineering cells and exosomes that have therapeutic activity for the treatment of vascular injury.

Abstract: Provided are stem cell biomimetic microparticles comprised of at least one stem cell-derived paracrine polypeptide or growth factor embedded in a polymer core particle that further comprises an outer layer of at least one fragment of a cell membrane of a stem cell disposed on the core particle. The polymer core may be constituted of any biocompatible and biodegradable polymer or copolymer, or a combination thereof that allows the embedding of the paracrine factors and their prolonged release from the core. The core and hence the microparticles can be biodegradable, allowing eventual elimination from the recipient animal or human subject. The core particles are sized to allow both transport through blood vessels and extravasation from the blood vessels into the surrounding tissues. The core particle may further include at least one polypeptide or peptide growth factor to induce the generation and proliferation of a population of stem cells.

Abstract: Several embodiments relate to methods of repairing and/or regenerating damaged or diseased tissue comprising administering to the damaged or diseased tissues compositions comprising exosomes. In several embodiments, the exosomes comprise one or more microRNA that result in alterations in gene or protein expression, which in tum result in improved cell or tissue viability and/or function.

Abstract: The present application relates to the producing field of honeycomb cores, and provides an aluminum honeycomb core production method and device, the method comprises: a gumming step: gumming adhesive to aluminum foil layers and then bond the aluminum foil layers to form a double/multi-layer aluminum foil; a pre-gumming step: gumming adhesive to the surface of the double/multi-layer aluminum foil; a cutting step: cutting the double/multi-layer aluminum foil; and a bonding step: bonding a plurality of the aluminum foil strips; and the apparatus is used to produce the aluminum honeycomb core according to the above method; the method can improve the structural strength and of the honeycomb core by applying aluminum foil to the honeycomb, and the apparatus can increase the production efficiency and the product quality of the aluminum honeycomb core.

Abstract: A motion simulating device includes a positioning unit, at least one carrier unit adapted for carrying at least one user, at least one motion mechanism, and a display unit for displaying image information for viewing by the at least one user. The at least one motion mechanism includes a motion arm, a first driver, and a second driver. The motion arm has a first end portion connected to the positioning unit and pivotable relative to the positioning unit about a first axis, and a second end portion opposite to the first end portion. The at least one carrier unit is connected to the second end portion of the motion arm and pivotable relative to the motion arm about a second axis.

Abstract: Several embodiments relate to methods of repairing and/or regenerating damaged or diseased tissue comprising administering to the damaged or diseased tissues compositions comprising exosomes. In several embodiments, the exosomes comprise one or more microRNA that result in alterations in gene or protein expression, which in turn result in improved cell or tissue viability and/or function.

Abstract: A kinesthetic device that simulates flight includes a base unit and a swing unit. The base unit includes a base seat; whereas, the swing unit includes a swing seat, two swing support structures pivoted between the base seat and the swing seat, and a swing actuator used to control the swing positions of the two swing support structures. The two swing support structures are equal in length and parallel to each other. A fixed baseline is formed between two junction points between the two swing support structures and the base seat, a swing baseline is formed between two junction points between the two swing support structures and the swing seat, and the fixed baseline and the swing baseline are equal in length. The two swing support structures, the fixed baseline and the swing baseline form a parallelogram, allowing the swing support structures to swing stably the base seat.

Abstract: A kinesthetic device that simulates flight includes a base unit and a swing unit. The base unit includes a base seat; whereas, the swing unit includes a swing seat, two swing support structures pivoted between the base seat and the swing seat, and a swing actuator used to control the swing positions of the two swing support structures. The two swing support structures are equal in length and parallel to each other. A fixed baseline is formed between two junction points between the two swing support structures and the base seat, a swing baseline is formed between two junction points between the two swing support structures and the swing seat, and the fixed baseline and the swing baseline are equal in length. The two swing support structures, the fixed baseline and the swing baseline form a parallelogram, allowing the swing support structures to swing stably the base seat.

Abstract: Various embodiments of a device for mitral valve repair are described. In one example, the device can be used to place a pair of magnets between the flaps of the mitral valve. The magnets hold the flaps together near its center, with a result similar to that achieved through the Alfieri stitch. To place the magnets, the device is inserted through the apex of the heart in a transapical procedure and extended up into the left ventricle toward the mitral valve. When in position with the mitral valve, a pair of grasper fingers of the device are used to place the pair of magnets over the flaps, and the magnets are released. Once released, magnetic attraction between the magnets holds the flaps together. In other embodiments, the device can be used to place staples or sutures or other bonding elements over the flaps of the mitral valve.

Abstract: The present application discloses a web engine startup method, comprising: displaying a transition image; starting up the web engine; and displaying page content; wherein in displaying page content, said web engine reuses the graphics buffer used to display the transition image; said graphics buffer is used to store the outputted user interface data for the display service module to display it. The present application simultaneously offers a web engine startup device. The web engine startup method offered in the present application is used because the same graphics buffer is reused in the web engine startup process and the transition image display process; therefore, not only is fast feedback to user input achieved during the web engine startup process, but there is also no additional buffer overhead generated as a result of displaying the transition image, which conserves memory utilization.

Abstract: The invention relates to a method of treating pleural abnormalities in a subject in need thereof, comprising the steps of: (a) attaching a biodegradable polymeric membrane onto a pleural wound to elicit fibronectin from fibroblasts to cause fibrous adhesion; and (b) securing the membrane with securement products, including sutures, staples, and sealants. The present invention also relates to a biodegradable adhesion membrane used for treating pleural abnormalities, comprising: a biodegradable base material selected from the group consisting of polycaprolactone (PCL), polylactic acid or polylactide (PLA), polyhydroxybutyrate (PHB), poly(ethylene adipate), poly(butylene adipate) (PBA), chitosan, hyaluronic acid, and polyglycolic acid (PGA); wherein the thickness of the membrane is 0.1-1 mm.

Abstract: In a radio frequency (RF) amplifier system and a heat dissipation device thereof, the RF amplifier system includes an RF amplifier and a heat dissipation device. The RF amplifier includes an RF power element. The heat dissipation device includes a heat conduction board, a plurality of heat pipes and fins. The heat conduction board is thermally conductively coupled to the RF power element, and one end of the heat pipe is thermally conductively coupled to the heat conduction board. The fins are arranged in parallel and spaced from each other. The other end of each of the heat pipes is inserted through the fins. The heat of the RF power element is conducted to the heat conduction board and the heat pipe, and then the heat is quickly conducted to the fins to be dissipated away quickly, and the RF power element can quickly reach a stable temperature.

Abstract: A latch device comprises a housing unit, a disk unit, an electromagnetic lock unit, a pressing lock unit, and a detecting unit. The housing unit includes a housing, which has a pressing hole and an insertion slot. The disk unit includes a supporting rod positioned through the housing, and two vertical disks pivotally arranged to the supporting rod. The outer perimeter of the two disks is placed with a hook, a first engaging portion and a second engaging portion. The electromagnetic lock unit includes two electromagnetic mechanisms, two retractable bars connected to the two electromagnetic mechanisms, and two electromagnetic latches respectively connected to the two retractable bars. The pressing lock unit includes a pushbutton, and a button latch connected to the pushbutton. The detecting unit includes two detectors, which are disposed inside the housing for detecting the position of the two electromagnetic latches.

Abstract: Several embodiments relate to methods of repairing and/or regenerating damaged or diseased tissue comprising administering to the damaged or diseased tissues compositions comprising exosomes. In several embodiments, the exosomes comprise one or more microRNA that result in alterations in gene or protein expression, which in turn result in improved cell or tissue viability and/or function.

Abstract: A battery-accommodating waterproof container includes a housing, a transmission base, a battery-holding seat and a locking cover module. The housing has a first opening, a second opening and a plurality of wedging holes. The transmission base is fixed on the first opening, and has a bottom board, an electricity transferring seat and a bottom-sealing element disposed between the bottom board and the housing. The battery-holding seat is received in the housing for receiving a battery therein. The electricity transferring seat transfers electricity of the battery outside the transmission base. The locking cover module is disposed on the second opening of the housing, and has a covering lid, a plurality of locking tabs and a pushing unit. The pushing unit drives the locking tabs to respectively wedge in the wedging holes of the housing, so as to retain the battery-holding seat in the housing.

Abstract: Several embodiments relate to methods of repairing and/or regenerating damaged or diseased tissue comprising administering to the damaged or diseased tissues compositions comprising exosomes. In several embodiments, the exosomes comprise one or more microRNA that result in alterations in gene or protein expression, which in turn result in improved cell or tissue viability and/or function.

Abstract: This invention relates generally to the discovery of novel mammalian lung spheroids and lung spheroid cells and uses thereof.

Abstract: In a radio frequency (RF) amplifier system and a heat dissipation device thereof, the RF amplifier system includes an RF amplifier and a heat dissipation device. The RF amplifier includes an RF power element. The heat dissipation device includes a heat conduction board, a plurality of heat pipes and fins. The heat conduction board is thermally conductively coupled to the RF power element, and one end of the heat pipe is thermally conductively coupled to the heat conduction board. The fins are arranged in parallel and spaced from each other. The other end of each of the heat pipes is inserted through the fins. The heat of the RF power element is conducted to the heat conduction board and the heat pipe, and then the heat is quickly conducted to the fins to be dissipated away quickly, and the RF power element can quickly reach a stable temperature.

Abstract: A second service component-oriented information entity sent by a first service component is sent to a second service component that processes the information entity, so that interaction between the service components based on the information entity is realized, and the association between the service components is also realized. A service component in an operating system can execute a specific function or provide a specific service. The function or service can be provided by the system or an application program. The information entity can transmitted among multiple service components to perform a function or service.

Abstract: An electronic device includes a cabinet, a number of chasses received in the cabinet, a number of first slide rails mounted to the cabinet, a second slide rail mounted to each chasses fitting about the corresponding first slide rail, a rotating member connected to the cabinet, and a resilient member installed between the rotating member and the cabinet. The rotating member includes an abutting bar and a stopper bar opposite to the abutting bar. A front end of each second slide rail forms a first guiding surface. A block protrudes from the front end of each second slide rail. When one of the chasses is pulled out from the cabinet, the first guiding surface abuts against the abutting bar to rotate away from the chasses, the stopper bar is rotated to adjacent to the chasses to latch the blocks of the other chasses, and deforming the resilient member.