Abstract: The heterocyclic alkynyl benzene compounds of formula (I), their pharmaceutically acceptable salts and stereoisomers thereof, as well as application in preparing drugs for preventing or treating tumors. The compounds can overcome the clinically induced resistance against Gleevec.

Abstract: An efficient approach for estimating scalefactors for use in the quantization of audio signal spectrum values is described. The scalefactor estimation approach can be implemented in multiple stages. A first stage estimates a distortion level for a selected scalefactor band spectrum value based on a received maximum tolerant distortion threshold and the spectrum values in the scalefactor band. A second stage determines an interim process value based on the previously estimated distortion level and generates a scalefactor for a selected scalefactor band spectrum value based on the generated interim process value and a statistically predetermined fraction. A third stage generates a scalefactor that applies to the whole scalefactor band based on the scalefactor generated for the selected scalefactor band spectrum value. The approach provides a performance gain of 40% over previous techniques, thereby reducing device power requirements and audio encoder bottlenecks.

Abstract: A method of processing an image includes the steps of receiving selection of the first region of interest (ROI) of an image, processing the first image data related to the first ROI, displaying the first image ROI based on the first image data, receiving selection of the second ROI of the image, which at least partially overlapping the first ROI, processing the second image data related to a portion of the second ROI that does not overlap the first ROI, combining the processed second image data with the processed first image data that overlaps the second ROI, and displaying the second image ROI based on the combined processed second image data and the processed first data.

Abstract: The invention relates to small molecules which function as inhibitors of the interaction between p53 and MDM2. The invention also relates to the use of these compounds for inhibiting cell growth, inducing cell death, inducing cell cycle arrest and/or sensitizing cells to additional agent(s).

Abstract: A system for downloading student homework and analyzing homework and a method thereof are provided. A teacher uploads a lesson file to a server through a data providing client for a student to download the lesson file conveniently, and the student uploads a homework file to the server through a mobile client for the server to find wrong answer content to perform answering content similarity analysis and provide an analysis result to the data providing client, so as to achieve the technical efficacy of providing digital homework to a student conveniently and analyzing student homework plagiarism fast.

Abstract: For a three-dimensional desktop switching system on a handheld apparatus and a method thereof, a selected program desktop and a selected designated desktop are switched fast through a program desktop selection instruction and a designated desktop selection instruction, so as to reduce the number of times of performing operations and the number of times of performing loading and update during desktop switching, thereby achieving the technical efficacy of fast switching a program desktop and a designated desktop of the handheld apparatus.

Abstract: A system for precisely positioning a document page number of a handheld apparatus and a method thereof are provided. When a document is opened, a sliding positioning element is provided, and an adjustment range is calculated according to a current page number of the document, so that the sliding positioning element achieves the technical efficacy of precisely positioning a page number of document content in the calculated adjustment range.

Abstract: Apparatus having corresponding methods comprise a processing core performance monitoring module adapted to receive indications of performance levels of a plurality of processing cores, the plurality of processing cores comprising a central processing unit (CPU), a video accelerator, and a graphics accelerator; a video accelerator performance monitoring module adapted to receive an indication of a performance level of the video accelerator; a graphics accelerator performance monitoring module adapted to receive an indication of a performance level of the graphics accelerator; and a processor core management module adapted to dynamically allocate at least one of a pre-processing task and a post-processing task of a multimedia workload to any one of the video accelerator, the graphics accelerator, and the CPUprocessing cores based on the performance levels of the video accelerator, the graphics accelerator, and the CPU.

Abstract: An efficient approach for estimating scalefactors for use in the quantization of audio signal spectrum values is described. The scalefactor estimation approach can be implemented in multiple stages. A first stage estimates a distortion level for a selected scalefactor band spectrum value based on a received maximum tolerant distortion threshold and the spectrum values in the scalefactor band. A second stage determines an interim process value based on the previously estimated distortion level and generates a scalefactor for a selected scalefactor band spectrum value based on the generated interim process value and a statistically predetermined fraction. A third stage generates a scalefactor that applies to the whole scalefactor band based on the scalefactor generated for the selected scalefactor band spectrum value. The approach provides a performance gain of 40% over previous techniques, thereby reducing device power requirements and audio encoder bottlenecks.

Abstract: A method of processing an image includes the steps of receiving selection of the first region of interest (ROI) of an image, processing the first image data related to the first ROI, displaying the first image ROI based on the first image data, receiving selection of the second ROI of the image, which at least partially overlapping the first ROI, processing the second image data related to a portion of the second ROI that does not overlap the first ROI, combining the processed second image data with the processed first image data that overlaps the second ROI, and displaying the second image ROI based on the combined processed second image data and the processed first data.

Abstract: The heterocyclic alkynyl benzene compounds of formula (I), their pharmaceutically acceptable salts and stereoisomers thereof, as well as application in preparing drugs for preventing or treating tumors. The compounds can overcome the clinically induced resistance against Gleevec.

Abstract: A business object model, which reflects data that is used during a given business transaction, is utilized to generate interfaces. This business object model facilitates commercial transactions by providing consistent interfaces that are suitable for use across industries, across businesses, and across different departments within a business during a business transaction. In some operations, software creates, updates, or otherwise processes information related to Indian employee payroll input, Indian social insurance arrangement, and Indian tax arrangement business objects.

Abstract: The invention relates to small molecules which function as inhibitors of the interaction between p53 and MDM2. The invention also relates to the use of these compounds for inhibiting cell growth, inducing cell death, inducing cell cycle arrest and/or sensitizing cells to additional agent(s).

Abstract: The invention relates to small molecules which function as inhibitors of the interaction between p53 and MDM2. The invention also relates to the use of these compounds for inhibiting cell growth, inducing cell death, inducing cell cycle arrest and/or sensitizing cells to additional agent(s).

Abstract: A method of processing an image includes the steps of receiving selection of the first region of interest (ROI) of an image, processing the first image data related to the first ROI, displaying the first image ROI based on the first image data, receiving selection of the second ROI of the image, which at least partially overlapping the first ROI, processing the second image data related to a portion of the second ROI that does not overlap the first ROI, combining the processed second image data with the processed first image data that overlaps the second ROI, and displaying the second image ROI based on the combined processed second image data and the processed first data.

Abstract: The invention relates to small molecules which function as inhibitors of the interaction between p53 and MDM2. The invention also relates to the use of these compounds for inhibiting cell growth, inducing cell death, inducing cell cycle arrest and/or sensitizing cells to additional agent(s).

Abstract: The compounds according to formula (VIII), their pharmaceutically acceptable acid or base addition salts, and the uses thereof. These compounds and their pharmaceutically acceptable acid or base addition salts can be used for preparing medicaments for modulating estrogen related receptors (ERR), and treating metabolic diseases, such as high blood fat, fatty liver, hyperglycemia, diabetes, obesity. The substituents of the formula are defined in the description.

Abstract: The compounds according to formula VIII, their pharmaceutically acceptable acid or base addition salts, and the uses thereof is disclosed. These compounds and their pharmaceutically acceptable acid or base addition salts can be used for the preparing a medicament for modulating estrogen related receptor (ERR), and treating metabolic diseases, such as high blood fat, fatty liver, hyperglycemia, diabetes, obesity, etc. The definition of the groups of the formula is defined as the description.

Abstract: The invention relates to small molecules which function as inhibitors of the interaction between p53 and MDM2. The invention also relates to the use of these compounds for inhibiting cell growth, inducing cell death, inducing cell cycle arrest and/or sensitizing cells to additional agent(s).

Abstract: The invention relates to small molecules which function as inhibitors of the interaction between p53 and MDM2. The invention also relates to the use of these compounds for inhibiting cell growth, inducing cell death, inducing cell cycle arrest and/or sensitizing cells to additional agent(s).