Abstract: The object of the present invention is to provide a printed circuit board that improves the heat radiating effect as the entire printed circuit board and a manufacturing method for such a printed circuit board.

Abstract: The purpose of the present invention is to provide a polymeric compound in which a camptothecin compound and an anti-cancer effect enhancer, particularly a PARP inhibitor, are bound to a single molecule, whereby it becomes possible to reduce the toxicity to normal cells and deliver and release the two components to an affected area with high efficiency to thereby improve the pharmacological efficacy of the two components. Provided is a polymeric compound represented by general formula (1).

Abstract: The object of the present invention is to provide a printed circuit board that improves the heat radiating effect as the entire printed circuit board and a manufacturing method for such a printed circuit board.

Abstract: A diagnostic imaging catheter is disclosed, which includes a sheath that is inserted into a body-cavity in a living body; an ultrasound transducer that is inserted into the sheath and is able to transmit and receive an ultrasound wave; a connector unit that is provided in a proximal portion of the sheath, an electrode terminal that is disposed inside the connector unit and is electrically connected to an external electrode terminal included in an external apparatus which transmits and receives an electrical signal with respect to the ultrasound transducer; a conductive member that is provided inside the connector unit, is electrically connected to a positive electrode and a negative electrode of the electrode terminal, and causes both the electrodes to be in a short-circuit state; and a switch unit that is configured to be able to cancel the short-circuit state of both the electrodes caused by the conductive member.

Abstract: A diagnostic imaging catheter is disclosed, which includes a sheath that is inserted into a body-cavity in a living body, an ultrasound transducer that is inserted into the sheath and is able to transmit and receive an ultrasound wave, a housing that accommodates the ultrasound transducer, and a drive shaft that includes the housing at the distal end and is rotatably provided inside the sheath. A first region A1 positioned on the distal side closer than the ultrasound transducer in the housing and a second region A2 positioned on the proximal side closer than the ultrasound transducer in the housing are formed so as to have X-ray contrast properties higher than that of an intermediate region A3 positioned between the first region and the second region.

Abstract: An imaging apparatus is disclosed for diagnosis, which can automatically discriminate an optical refractive index of flushing liquid which is utilized during pull-back scanning, and reconstruct a blood vessel cross-sectional image having an appropriate scale. An intensity of reflected light in a medium having a known refractive index is obtained in advance. An intensity of the reflected light on a border surface between a catheter sheath unit and the flushing liquid is detected based on interference light data, which is obtained during the pull-back scanning. The refractive index of the flushing liquid is calculated based on the intensity of the reflected light, an intensity of incident light obtained from the stored reflected light, and a known refractive index of the catheter sheath unit.

Abstract: A rail bond which achieves high durability and high reliability in response to vibration caused by running of trains is provided. [Solving Means] A rail bond according to the present invention includes a conductor that electrically connects rails separately adjacent to each other, terminals electrically connected to the conductor and welded on side surfaces of the rails, and end-edges at which the conductor is connected to the terminals. Each of the terminals has a welding region welded on the side surface of the rail, and, in a direction almost perpendicular to the side surface of the rail, the welding region, the terminal, the end-edge, and the conductor have a predetermined relationship with respect to at least one of positions, mutual shapes, lamination, and a lamination structure.

Abstract: The purpose of the present invention is to provide a polymeric compound in which a camptothecin compound and an anti-cancer effect enhancer, particularly a PARP inhibitor, are bound to a single molecule, whereby it becomes possible to reduce the toxicity to normal cells and deliver and release the two components to an affected area with high efficiency to thereby improve the pharmacological efficacy of the two components. Provided is a polymeric compound represented by general formula (1).

Abstract: Provided is an X-ray generation device including an X-ray tube and a high-voltage generation unit arranged inside a housing and also having insulating oil filled in the housing, which uses no lead and is small in size, thereby achieving a reduction in manufacturing cost, and which also has high cooling performance.

Abstract: Provided is an X-ray generation device including an X-ray tube and a high-voltage generation unit arranged inside a housing and also having insulating oil filled in the housing, which uses no lead and is small in size, thereby achieving a reduction in manufacturing cost, and which also has high cooling performance.

Abstract: [Problems] A derivative of a nucleic acid antimetabolite is demanded which can show a high therapeutic effect at a low dose. [Means For Solving Problems] Disclosed is a high molecular weight derivative of a nucleic acid antimetabolite, which is characterized by comprising a high molecular weight compound comprising a polyethylene glycol moiety and a polymer moiety having a carboxyl group in a side chain and a nucleoside derivative which can act as a nucleic acid antimetabolite, wherein the carboxyl group in the side chain is bound to a hydroxyl group in the nucleoside derivative via an ester bond. Also disclosed is a method for producing the high molecular weight derivative.

Abstract: Provided is an X-ray irradiator which reduces the occurrence of discharge resulting from the difference in electric potential in the X-ray irradiator, and which concurrently achieves reduction in size and weight. In an X-ray irradiator (1), an X-ray tube (11) and a high-voltage generator (2) are installed inside a casing (18), and an insulation oil (13) is filled in the casing (18). The high-voltage generator (2) is configured by arranging and electrically connecting together multiple ring-shaped voltage amplifying units (21). An anode (14) and a cathode (15) of the X-ray tube (11) are fitted in and thus installed in hollow portions of the voltage amplifying units (21).

Abstract: [Problems] A derivative of a nucleic acid antimetabolite is demanded which can show a higher therapeutic effect at a lower dose. [Means for Solving Problems] Disclosed is a high molecular weight derivative a nucleic acid antimetabolite, which is characterized by comprising a high molecular weight compound comprising a polyethylene glycol moiety and a polymer moiety having a carboxyl group in a side chain and a nucleoside derivative which can act as a nucleic acid antimetabolite, wherein the nucleoside derivative is bound to the carboxyl group in the side chain of the high molecular weight compound via a highly hydrophobic linker.

Abstract: Provided is an X-ray irradiator which reduces the occurrence of discharge resulting from the difference in electric potential in the X-ray irradiator, and which concurrently achieves reduction in size and weight. In an X-ray irradiator (1), an X-ray tube (11) and a high-voltage generator (2) are installed inside a casing (18), and an insulation oil (13) is filled in the casing (18). The high-voltage generator (2) is configured by arranging and electrically connecting together multiple ring-shaped voltage amplifying units (21). An anode (14) and a cathode (15) of the X-ray tube (11) are fitted in and thus installed in hollow portions of the voltage amplifying units (21).

Abstract: [Problems] A derivative of a nucleic acid antimetabolite is demanded which can show a higher therapeutic effect at a lower dose. [Means for Solving Problems] Disclosed is a high molecular weight derivative a nucleic acid antimetabolite, which is characterized by comprising a high molecular weight compound comprising a polyethylene glycol moiety and a polymer moiety having a carboxyl group in a side chain and a nucleoside derivative which can act as a nucleic acid antimetabolite, wherein the nucleoside derivative is bound to the carboxyl group in the side chain of the high molecular weight compound via a highly hydrophobic linker.

Abstract: [Problems] A derivative of a nucleic acid antimetabolite is demanded which can show a high therapeutic effect at a low dose. [Means For Solving Problems] Disclosed is a high molecular weight derivative of a nucleic acid antimetabolite, which is characterized by comprising a high molecular weight compound comprising a polyethylene glycol moiety and a polymer moiety having a carboxyl group in a side chain and a nucleoside derivative which can act as a nucleic acid antimetabolite, wherein the carboxyl group in the side chain is bound to a hydroxyl group in the nucleoside derivative via an ester bond. Also disclosed is a method for producing the high molecular weight derivative.

Abstract: A pulverized coal combustion boiler 100 comprising: a furnace 50; a plurality of burners 6 for supplying and burning pulverized coal fuel in the furnace arranged at positions of a plurality of stages having different heights on a furnace front wall 51 and a furnace rear wall 52 of furnace wall surfaces forming the furnace 50, the furnace rear wall 52 arranged for facing the furnace front wall 51; a plurality of mills 2 arranged for supplying the pulverized coal fuel to the plurality of burners 6 arranged at each of the plurality of stages; and pulverized fuel pipes 5 arranged for distributing and supplying the pulverized coal to the plurality of burners 6 at each of the stages of the furnace front wall 51 and the furnace rear wall 52 from each of the plurality of mills 2.

Abstract: A 3-phenyltetrahydrocinnolin-5-ol derivative represented by the following general formula (1) (wherein Z represents 2-carboxyethyl, 3-dimethylaminopropyl etc.; X represents trifluoromethyl etc.; X? represents hydrogen, etc.; and Y anti Y? each represents methyl, hydrogen, etc.), a physiologically acceptable salt thereof, or a prodrug of either. They have cytostatic activity against tumor cells and hence are effective as an antitumor agent.

Abstract: A flow proportioning assembly for dividing a portion of a fluid flow such as gas for presentation to a sensor includes a holder member having a central opening and forming an exterior peripheral passageway when inserted within a conduit of a flow meter housing. A resistor member can be adjustably mounted in the central opening downstream of a holder member aperture to encourage a laminar flow pattern and a large entrance port and a large exit port can communicate with a passageway that is operatively connected with a sensor. The exit port is downstream of the resistor member. Flexible fastener members can engage the resistor member and the holder member for ease of mounting. The resistor member can also comprise a helical arrangement of small fluid passageways to encourage laminar flow.