Patents by Inventor Keiji Kamiyama

Keiji Kamiyama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Salts of benzimidazole compound and use thereof
    Patent number: 8809542
    Abstract: A sodium salt, magnesium salt, lithium salt, potassium salt, calcium salt or barium salt of (R)-2 -[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2 -pyridinyl]methyl]sulfinyl]-1H-benzimidazole, and a pharmaceutical composition comprising the salt. The novel salt is useful as an excellent antiulcer agent.
    Type: Grant
    Filed: May 29, 2013
    Date of Patent: August 19, 2014
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Keiji Kamiyama, Hideo Hashimoto
  • SALTS OF BENZIMIDAZOLE COMPOUND AND USE THEREOF
    Publication number: 20130281704
    Abstract: A sodium salt, magnesium salt, lithium salt, potassium salt, calcium salt or barium salt of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole, and a pharmaceutical composition comprising the salt. The novel salt is useful as an excellent antiulcer agent.
    Type: Application
    Filed: May 29, 2013
    Publication date: October 24, 2013
    Inventors: Keiji KAMIYAMA, Hideo HASHIMOTO
  • Benzimidazole compound crystal
    Patent number: 8552198
    Abstract: A novel crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole or a salt thereof of the present invention is useful for an excellent antiulcer agent.
    Type: Grant
    Filed: August 22, 2012
    Date of Patent: October 8, 2013
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Akira Fujishima, Isao Aoki, Keiji Kamiyama
  • BENZIMIDAZOLE COMPOUND CRYSTAL
    Publication number: 20120316344
    Abstract: A novel crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole or a salt thereof of the present invention is useful for an excellent antiulcer agent.
    Type: Application
    Filed: August 22, 2012
    Publication date: December 13, 2012
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Akira FUJISHIMA, Isao AOKI, Keiji KAMIYAMA
  • BENZIMIDAZOLE COMPOUND CRYSTAL
    Publication number: 20110319450
    Abstract: A novel crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole or a salt thereof of the present invention is useful for an excellent antiulcer agent.
    Type: Application
    Filed: September 1, 2011
    Publication date: December 29, 2011
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Akira FUJISHIMA, Isao AOKI, Keiji KAMIYAMA
  • Benzimidazole compound crystal
    Patent number: 8030333
    Abstract: A novel crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole or a salt thereof of the present invention is useful for an excellent antiulcer agent.
    Type: Grant
    Filed: April 30, 2010
    Date of Patent: October 4, 2011
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Akira Fujishima, Isao Aoki, Keiji Kamiyama
  • BENZIMIDAZOLE COMPOUND CRYSTAL
    Publication number: 20100222391
    Abstract: A novel crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole or a salt thereof of the present invention is useful for an excellent antiulcer agent.
    Type: Application
    Filed: April 30, 2010
    Publication date: September 2, 2010
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Akira FUJISHIMA, Isao AOKI, Keiji KAMIYAMA
  • Benzimidazole compound crystal
    Patent number: 7737282
    Abstract: A novel crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole or a salt thereof of the present invention is useful for an excellent antiulcer agent.
    Type: Grant
    Filed: February 26, 2009
    Date of Patent: June 15, 2010
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Akira Fujishima, Isao Aoki, Keiji Kamiyama
  • Benzimidazole compound crystal
    Patent number: 7569697
    Abstract: A novel crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl],sulfinyl]-1H-benzimidazole or a salt thereof of the present invention is useful for an excellent antiulcer agent.
    Type: Grant
    Filed: January 7, 2008
    Date of Patent: August 4, 2009
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Akira Fujishima, Isao Aoki, Keiji Kamiyama
  • BENZIMIDAZOLE COMPOUND CRYSTAL
    Publication number: 20090163553
    Abstract: A novel crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole or a salt thereof of the present invention is useful for an excellent antiulcer agent.
    Type: Application
    Filed: February 26, 2009
    Publication date: June 25, 2009
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Akira FUJISHIMA, Isao AOKI, Keiji KAMIYAMA
  • Prodrugs of imidazole derivatives, for use as proton pump inhibitors in the treatment of e.g. peptic ulcers
    Patent number: 7410981
    Abstract: An imidazole compound represented by the formula (I), a salt thereof and a compound of the formula (V), which is one of the intermediates thereof. wherein each symbol is as defined in the present specification. The compound of the present invention shows a superior anti-ulcer activity, a gastric acid secretion inhibitory action, a mucosa-protecting action, an anti-Helicobacter pylori action and the like. Since it shows low toxicity, the compound is useful as a pharmaceutical product.
    Type: Grant
    Filed: June 13, 2003
    Date of Patent: August 12, 2008
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Keiji Kamiyama, Hiroshi Banno, Fumihiko Sato
  • Benzimidazole compound crystal
    Publication number: 20080132547
    Abstract: A novel crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl],sulfinyl]-1H-benzimidazole or a salt thereof of the present invention is useful for an excellent antiulcer agent.
    Type: Application
    Filed: January 7, 2008
    Publication date: June 5, 2008
    Applicant: TAKEDA PHARMACEUTICAL COMPANY LIMITED
    Inventors: Akira Fujishima, Isao Aoki, Keiji Kamiyama
  • Benzimidazole compound crystal
    Patent number: 7339064
    Abstract: A novel crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole or a salt thereof of the present invention is useful for an excellent antiulcer agent.
    Type: Grant
    Filed: June 10, 2005
    Date of Patent: March 4, 2008
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Akira Fujishima, Isao Aoki, Keiji Kamiyama
  • Salts of benzimidazole compound and use thereof
    Publication number: 20070254924
    Abstract: A sodium salt, magnesium salt, lithium salt, potassium salt, calcium salt or barium salt of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole, and a pharmaceutical composition comprising the salt. The novel salt is useful as an excellent antiulcer agent.
    Type: Application
    Filed: June 12, 2007
    Publication date: November 1, 2007
    Applicant: Takeda Pharmaceutical Company Limited
    Inventors: Keiji Kamiyama, Hideo Hashimoto
  • Salts of benzimidazole compound and use thereof
    Patent number: 7271182
    Abstract: A sodium salt, magnesium salt, lithium salt, potassium salt, calcium salt or barium salt of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole, and a pharmaceutical composition comprising the salt. The novel salt is useful as an excellent antiulcer agent.
    Type: Grant
    Filed: August 3, 2001
    Date of Patent: September 18, 2007
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Keiji Kamiyama, Hideo Hashimoto
  • Crystals of benzimidazole compounds
    Publication number: 20070155796
    Abstract: Crystals of (S)-2[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole or salts thereof, useful as excellent antiulcer drugs.
    Type: Application
    Filed: February 1, 2007
    Publication date: July 5, 2007
    Inventors: Akira Fujishima, Isao Aoki, Keiji Kamiyama
  • Crystals of benzimidazole compounds
    Patent number: 7189744
    Abstract: Crystals of (S)-2[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole or salts thereof, useful as excellent antiulcer drugs.
    Type: Grant
    Filed: April 1, 2005
    Date of Patent: March 13, 2007
    Assignee: Takeda Pharmaceutical Company, Limited
    Inventors: Akira Fujishima, Isao Aoki, Keiji Kamiyama
  • Prodrug and process for producing the same
    Publication number: 20060293371
    Abstract: The present invention provides a compound having, as a modification group to be eliminated from a prodrug, a group represented by the formula: wherein each symbol is as defined in the specification. According to the present invention, the development of a prodrug based on the modification of a nitrogen-containing heterocycle and the like has become possible.
    Type: Application
    Filed: June 13, 2003
    Publication date: December 28, 2006
    Applicant: Takeda Pharmaceuticals North America, Inc.
    Inventor: Keiji Kamiyama
  • Benzimidazole compound crystal
    Publication number: 20050228026
    Abstract: A novel crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole or a salt thereof of the present invention is useful for an excellent antiulcer agent.
    Type: Application
    Filed: June 10, 2005
    Publication date: October 13, 2005
    Inventors: Akira Fujishima, Isao Aoki, Keiji Kamiyama
  • Prodrugs of imidazole derivatives, for use as proton pump inhibitors in the treatment of e.g. peptic ulcers
    Publication number: 20050222210
    Abstract: An imidazole compound represented by the formula (I), a salt thereof and a compound of the formula (V), which is one of the intermediates thereof. wherein each symbol is as defined in the present specification. The compound of the present invention shows a superior anti-ulcer activity, a gastric acid secretion inhibitory action, a mucosa-protecting action, an anti-Helicobacter pylori action and the like. Since it shows low toxicity, the compound is useful as a pharmaceutical product.
    Type: Application
    Filed: June 13, 2003
    Publication date: October 6, 2005
    Inventors: Keiji Kamiyama, Hiroshi Banno, Fumihiko Sato