Patents by Inventor Keiji Kamiyama

Keiji Kamiyama has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6939971
    Abstract: A novel crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole or a salt thereof of the present invention is useful for an excellent antiulcer agent.
    Type: Grant
    Filed: September 4, 2003
    Date of Patent: September 6, 2005
    Assignee: Takeda Pharmaceutical Company, Ltd.
    Inventors: Akira Fujishima, Isao Aoki, Keiji Kamiyama
  • Publication number: 20050171162
    Abstract: Crystals of (S)-2[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole or salts thereof, useful as excellent antiulcer drugs.
    Type: Application
    Filed: April 1, 2005
    Publication date: August 4, 2005
    Inventors: Akira Fujishima, Isao Aoki, Keiji Kamiyama
  • Patent number: 6903122
    Abstract: Crystals of (S)-2[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole or salts thereof, useful as excellent antiulcer drugs.
    Type: Grant
    Filed: June 23, 2003
    Date of Patent: June 7, 2005
    Assignee: Takeda Pharmaceutical Company Limited
    Inventors: Akira Fujishima, Isao Aoki, Keiji Kamiyama
  • Publication number: 20040248941
    Abstract: The present invention relates to a compound represented by the following formula 1
    Type: Application
    Filed: March 19, 2004
    Publication date: December 9, 2004
    Inventors: Keiji Kamiyama, Fumihiko Sato, Hiroshi Banno, Atsushi Hasuoka
  • Publication number: 20040082791
    Abstract: Crystals of (S)-2[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole or salts thereof, useful as excellent antiulcer drugs.
    Type: Application
    Filed: June 23, 2003
    Publication date: April 29, 2004
    Inventors: Akira Fujishima, Isao Aoki, Keiji Kamiyama
  • Publication number: 20040048898
    Abstract: A novel crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole or a salt thereof of the present invention is useful for an excellent antiulcer agent.
    Type: Application
    Filed: September 4, 2003
    Publication date: March 11, 2004
    Inventors: Akira Fujishima, Isao Aoki, Keiji Kamiyama
  • Publication number: 20040039027
    Abstract: A compound represented by the formula (I) 1
    Type: Application
    Filed: April 9, 2003
    Publication date: February 26, 2004
    Inventors: Keiji Kamiyama, Fumihiko Sato
  • Patent number: 6664276
    Abstract: A novel crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole or a salt thereof of the present invention is useful for an excellent antiulcer agent.
    Type: Grant
    Filed: September 13, 2002
    Date of Patent: December 16, 2003
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Akira Fujishima, Isao Aoki, Keiji Kamiyama
  • Publication number: 20030181487
    Abstract: A sodium salt, magnesium salt, lithium salt, potassium salt, calcium salt or barium salt of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole, and a pharmaceutical composition comprising the salt. The novel salt is useful as an excellent antiulcer agent.
    Type: Application
    Filed: January 28, 2003
    Publication date: September 25, 2003
    Inventors: Keiji Kamiyama, Hideo Hashimoto
  • Patent number: 6608092
    Abstract: Crystals of (S)-2[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole or salts thereof, useful as excellent antiulcer drugs.
    Type: Grant
    Filed: December 28, 2001
    Date of Patent: August 19, 2003
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Akira Fujishima, Isao Aoki, Keiji Kamiyama
  • Publication number: 20030045724
    Abstract: A novel crystal of (R)-2-[[[3-methyl-4-(2,2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole or a salt thereof of the present invention is useful for an excellent antiulcer agent.
    Type: Application
    Filed: September 13, 2002
    Publication date: March 6, 2003
    Inventors: Akira Fujishima, Isao Aoki, Keiji Kamiyama
  • Patent number: 6462058
    Abstract: A novel crystal of (R)-2-[[[3-methyl-4-(2, 2,2-trifluoroethoxy)-2-pyridinyl]methyl]sulfinyl]-1H-benzimidazole or a salt thereof of the present invention is useful for an excellent antiulcer agent.
    Type: Grant
    Filed: November 3, 2000
    Date of Patent: October 8, 2002
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Akira Fujishima, Isao Aoki, Keiji Kamiyama
  • Patent number: 6423869
    Abstract: A compound of the formula (I): wherein R1 represents an amino group which may be substituted; R2 represents a carboxy group which may be esterified or amidated; R3, R4, R5 and R6 each represent a hydroxy group which may be protected; Q represents an aryl group which may be substituted; or a salt thereof is disclosed. The compound (I) possesses ant-Helicobacter pylori activity, and is useful in the prevention or treatment of various diseases associated with Helicobacter bacteria, such as duodenal ulcer, gastric ulcer, chronic gastritis and cancer of the stomach.
    Type: Grant
    Filed: November 1, 1999
    Date of Patent: July 23, 2002
    Assignee: Takeda Chemical Industries, Inc.
    Inventors: Ken-ichiro Miyagawa, Shigetoshi Tsubotani, Masafumi Nakao, Yoshitaka Nakano, Keiji Kamiyama, Motoo Izawa, Yohko Akiyama, Yuji Nishikimi
  • Patent number: 6414003
    Abstract: An anti-Helicobacter pylori agent comprising a compound represented by the formula: wherein A represents an aromatic ring group which may be substituted; R1 and R2, whether identical or not, each represent a hydrogen atom or a hydrocarbon group which may be substituted; R3 and R4, whether identical or not, each represent a hydrogen atom, a hydrocarbon group which may be substituted, an acyl group, a carbamoyl group which may be substituted, or a carboxyl group which may be esterified; or a salt thereof.
    Type: Grant
    Filed: November 9, 2000
    Date of Patent: July 2, 2002
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Tsuneo Kanamaru, Masafumi Nakao, Hiroyuki Tawada, Keiji Kamiyama
  • Patent number: 6265586
    Abstract: A process for producing indolmycin or a salt thereof which comprises reacting a compound of the formula: or a salt thereof with methylamine or a salt thereof, can be produced in an optically active form in a high yield and high quality, and is advantageous from the industrial point of view.
    Type: Grant
    Filed: September 25, 2000
    Date of Patent: July 24, 2001
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Keiji Kamiyama, Yutaka Nakayama
  • Patent number: 6169102
    Abstract: An anti-Helicobacter pylori agent comprising a compound represented by the formula: wherein A represents an aromatic ring group which may be substituted; R1 and R2, whether identical or not, each represent a hydrogen atom or a hydrocarbon group which may be substituted; R3 and R4, whether identical or not, each represent a hydrogen atom, a hydrocarbon group which may be substituted, an acyl group, a carbamoyl group which may be substituted, or a carboxyl group which may be esterified; or a salt thereof.
    Type: Grant
    Filed: September 10, 1998
    Date of Patent: January 2, 2001
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Tsuneo Kanamaru, Masafumi Nakao, Hiroyuki Tawada, Keiji Kamiyama
  • Patent number: 5948774
    Abstract: Cephem compounds of the formula: ##STR1## wherein R.sup.1 is an optionally protected amino group; R.sup.2 is a fluoro-lower alkyl group; and the ring A may have further substituent(s), or their esters or salts, show broad and excellent antibacterial activities and are useful as antibacterial agents.
    Type: Grant
    Filed: July 29, 1997
    Date of Patent: September 7, 1999
    Assignee: Takeda Chemical Industries, Ltd.
    Inventors: Keiji Kamiyama, Kenji Okonogi, Akio Miyake