Abstract: The invention provides an S1P ligand-binding nucleic acid complex that is delivered to a target organ to regulate expression or editing of a target gene or a transcription or translation product thereof. The S1P ligand-binding nucleic acid complex includes a nucleic acid with an antisense oligonucleotide 12 to 30 nucleotides in length, and has a nucleic acid sequence complementary to a target transcription product, bound to a S1P ligand. The nucleic acid complex is useful for the treatment of a disease caused by such gene. The ligand-binding nucleic acid complex can be delivered to an organ, tissue, or cell in which the S1P receptor is expressed, such as the skeletal muscle, cardiac muscle, liver, kidney, lung, mammary gland, fat, podocyte, lymphocyte, or vascular endothelial cell.

Abstract: The magnet material is represented by a composition formula 1: (R1-xYx)aMbAc, where R is at least one element selected from the group consisting of rare-earth elements, M is at least one element selected from the group consisting of Fe and Co, A is at least one element selected from the group consisting of N, C, B, H and P, x is a number satisfying 0.01?x?0.8, a is a number satisfying 4?a?20 atomic %, b is a number satisfying b=100?a?c atomic %, and c is a number satisfying 0?c?18 atomic %), and includes a main phase having a Th2Ni17 crystal structure. A concentration of the element M in the main phase is 89.6 atomic % or more.

Abstract: A magnetic material is expressed by a composition formula 1: (R1-xYx)aMbTcZnd. R is at least one element selected from the group consisting of rare-earth elements, M is Fe or Fe and Co, T is at least one element selected from the group consisting of Ti, V, Nb, Ta, Mo, and W, x is a number satisfying 0.01?x?0.8, a is a number satisfying 4?a?20 atomic percent, b is a number satisfying b=100?a?c?d atomic percent, c is a number satisfying 0<c<7 atomic percent, and d is a number satisfying 0.01?d?7 atomic percent. The magnetic material includes: a main phase having a ThMn12 crystal phase; and a sub phase containing 50 atomic percent or more of Zn.

Abstract: A permanent magnet comprises crystal grains each including a main phase. An average size of the crystal grains is 1.0 ?m or less, and a degree of orientation of easy magnetization axes of the crystal grains to an easy magnetization axis of the magnet is 15% or more and 90% or less. A recoil magnetic permeability is 1.13 or more, a residual magnetization is 0.8 T or more and less than 1.16 T, and an intrinsic coercive force is 850 kA/m or more.

Abstract: A magnet material of an embodiment includes a composition represented by a formula 1: (Fe1-x-yCoxTy)2(B1-aAa)b, and a metallic structure having a CuAl2 crystal phase as a main phase. T is at least one element selected from V, Cr, and Mn. A is at least one element selected from C, N, Si, S, P, and Al. An atomic ratio x of Co and an atomic ratio y of the element T satisfy 0.01?y?0.5 and x+y?0.5. When the element T includes at least one element selected from V and Cr, a total atomic ratio of V and Cr is 0.03 or more. When the element T includes Mn, an atomic ratio of Mn is 0.3 or less. An atomic ratio a of the element A satisfies 0?a?0.4. A total atomic ratio b of B and the element A satisfies 0.8?b?1.2.

Abstract: In one embodiment, a permanent magnet includes a composition expressed by RpFeqMrCusCo100-p-q-r-s (R is a rare-earth element, M is at least one element selected from Zr, Ti, and Hf, 10?p?13.5 at %, 28?q?40 at %, 0.88?r?7.2 at %, and 3.5?s?13.5 at %), and a metallic structure including a cell phase having a Th2Zn17 crystal phase, and a cell wall phase. A Fe concentration (C1) in the cell phase is in a range from 28 at % to 45 at %, and a difference (C1?C2) between the Fe concentration (C1) in the cell phase and a Fe concentration (C2) in the cell wall phase is larger than 10 at %.

Abstract: A high performance permanent magnet is provided. The permanent magnet includes a composition represented by a composition formula: RpFeqMrCutCo100-p-q-r-t, and a metallic structure including cell phases having a Th2Zn17 crystal phase and Cu-rich phases having higher Cu concentration than the cell phases. An average diameter of the cell phases is 220 nm or less, and in a numeric value range from a minimum diameter to a maximum diameter of the cell phases, a ratio of a number of cell phases having a diameter in a numeric value range of less than upper 20% from the maximum diameter is 20% or less of all the cell phases.

Abstract: The magnet material is represented by a composition formula 1: (R1-xYx)aMbAc, where R is at least one element selected from the group consisting of rare-earth elements, M is at least one element selected from the group consisting of Fe and Co, A is at least one element selected from the group consisting of N, C, B, H and P, x is a number satisfying 0.01?x?0.8, a is a number satisfying 4?a?20 atomic %, b is a number satisfying b=100?a?c atomic %, and c is a number satisfying 0?c?18 atomic %), and includes a main phase having a Th2Ni17 crystal structure. A concentration of the element M in the main phase is 89.6 atomic % or more.

Abstract: The invention provides a high-performance permanent magnet. The permanent magnet has a composition that is expressed by a composition formula RpFeqMrCutCo100-p-q-r-t, where R is at least one element selected from a rare earth element, M is at least one element selected from the group consisting of Zr, Ti, and Hf, p is a number satisfying 10.8?p?12.5 atomic percent, q is a number satisfying 25?q?40 atomic percent, r is a number satisfying 0.88?r?4.5 atomic percent, and t is a number satisfying 3.5?t?13.5 atomic percent. The permanent magnet also has a metallic structure that includes a main phase having a Th2Zn17 crystal phase, and a Cu-M rich phase having a higher Cu concentration and a higher M concentration than the main phase.

Abstract: In one embodiment, a permanent magnet includes: a composition expressed by RpFeqMrCusCo100-p-q-r-s (R is a rare-earth element, M is at least one element selected from Zr, Ti, and Hf, 10?p?13.5 at %, 25?q?40 at %, 1.35?r?1.75 at %, and 0.88?s?13.5 at %); and a metallic structure including Th2Zn17 crystal phases each having a Fe concentration of 25 at % or more, and Cu-rich crystal phases each having a Cu concentration of from 25 at % to 70 at %. An average thickness of the Cu-rich crystal phases is 20 nm or less, and an average distance between the Cu-rich crystal phases is 200 nm or less.

Abstract: A magnetic material is expressed by a composition formula 1: (R1-xYx)aMbTcZnd. R is at least one element selected from the group consisting of rare-earth elements, M is Fe or Fe and Co, T is at least one element selected from the group consisting of Ti, V, Nb, Ta, Mo, and W, x is a number satisfying 0.01?x?0.8, a is a number satisfying 4?a?20 atomic percent, b is a number satisfying b=100?a?c?d atomic percent, c is a number satisfying 0<c<7 atomic percent, and d is a number satisfying 0.01?d?7 atomic percent. The magnetic material includes: a main phase having a ThMn12 crystal phase; and a sub phase containing 50 atomic percent or more of Zn.

Abstract: A permanent magnet comprises crystal grains each including a main phase. An average size of the crystal grains is 1.0 ?m or less, and a degree of orientation of easy magnetization axes of the crystal grains to an easy magnetization axis of the magnet is 15% or more and 90% or less. A recoil magnetic permeability is 1.13 or more, a residual magnetization is 0.8 T or more and less than 1.16 T, and an intrinsic coercive force is 850 kA/m or more.

Abstract: In one embodiment, a permanent magnet includes a sintered compact including: a composition expressed by a composition formula: RpFeqMrCusCo100-p-q-r-s (R is at least one element selected from rare-earth elements, M is at least one element selected from Zr, Ti, and Hf, 10?p?13.3 at %, 25?q?40 at %, 0.87?r?5.4 at %, and 3.5?s?13.5 at %); and a metallic structure having a main phase including a Th2Zn17 crystal phase, and an R-M-rich phase containing the element R whose concentration is 1.2 times or more an R concentration in the main phase and the element M whose concentration is 1.2 times or more an M concentration in the main phase. A volume fraction of the R-M-rich phase in the metallic structure is from 0.2% to 15%.

Abstract: In one embodiment, a permanent magnet includes a sintered compact having a composition expressed by a composition formula: Rp1Feq1Mr1Cus1Co100-p1-q1-r1-s1 (R is a rare-earth element, M is at least one element selected from Zr, Ti, and Hf, 10?p1?13.3 at %, 25?q1?40.0 at %, 0.88?r1?5.4 at %, and 3.5?s1?13.5 at %). The sintered compact includes crystal grains and a Cu-rich phase. The crystal grains are composed of a main phase including a Th2Zn17 crystal phase. The Cu-rich phase has a composition with a high Cu concentration and an average thickness of 0.05 ?m or more and 2 ?m or less.

Abstract: In one embodiment, a permanent magnet includes: a composition expressed by RpFeqMrCusCo100-p-q-r-s (R is a rare-earth element, M is at least one element selected from Zr, Ti, and Hf, 10.8?p?13.5 at %, 28?q?40 at %, 0.88?r?7.2 at %, and 3.5?s?13.5 at %); and a metallic structure including a cell phase having a Th2Zn17 crystal phase, and a cell wall phase. A Cu concentration in the cell wall phase is in a range from 30 at % to 70 at %.

Abstract: A permanent magnet comprises a plurality of crystal grains having a main phase of an R-Fe-B magnetic phase, R being at least one element selected from the group consisting of Nd, Pr, Dy, Tb, and Ho. A grain size distribution of the crystal grains satisfies a formula: d10<Rc<d90, the Rc indicating a single-domain critical grain size of the magnetic phase, the d10 indicating a grain size in which a cumulative frequency ratio in the grain size distribution is 10%, and the d90 indicating a grain size in which a cumulative frequency ratio in the grain size distribution is 90%.

Abstract: A magnet material of an embodiment includes a composition represented by a formula 1: (Fe1-x-yCoxTy)2(B1-aAa)b, and a metallic structure having a CuAl2 crystal phase as a main phase. T is at least one element selected from V, Cr, and Mn. A is at least one element selected from C, N, Si, S, P, and Al. An atomic ratio x of Co and an atomic ratio y of the element T satisfy 0.01?y?0.5 and x+y?0.5. When the element T includes at least one element selected from V and Cr, a total atomic ratio of V and Cr is 0.03 or more. When the element T includes Mn, an atomic ratio of Mn is 0.3 or less. An atomic ratio a of the element A satisfies 0?a?0.4. A total atomic ratio b of B and the element A satisfies 0.8?b?1.2.

Abstract: A magnet material of an embodiment includes a composition represented by a formula 1: (Fe1-x-yCoxTy)2(B1-aAa)b, and a metallic structure having a CuAl2 crystal phase as a main phase. T is at least one element selected from V, Cr, and Mn. A is at least one element selected from C, N, Si, S, P, and Al. An atomic ratio x of Co and an atomic ratio y of the element T satisfy 0.01?y?0.5 and x+y?0.5. When the element T includes at least one element selected from V and Cr, a total atomic ratio of V and Cr is 0.03 or more. When the element T includes Mn, an atomic ratio of Mn is 0.3 or less. An atomic ratio a of the element A satisfies 0?a?0.4. A total atomic ratio b of B and the element A satisfies 0.8?b?1.2.

Abstract: A magnetic material is expressed by a composition formula 1: (R1-xYx)aMbTcDd. The magnetic material includes: a main phase having a ThMn12 crystal phase, and a sub phase having a phase containing the element D.

Abstract: In one embodiment, a permanent magnet includes a sintered compact having a composition represented by the composition formula: RpFeqMrCusCo100-p-q-r-s (where R is at least one element selected from rare earth elements, M is at least one element selected from Zr, Ti, and Hf, p is 10.5 atomic % or more and 12.5 atomic % or less, q is 24 atomic % or more and 40 atomic % or less, r is 0.88 atomic % or more and 4.5 atomic % or less, and s is 3.5 atomic % or more and 10.7 atomic % or less. The sintered compact has a structure having crystal grains constituted of a main phase including a Th2Zn17 crystal phase, and a crystal grain boundary. In the structure of the sintered compact, an average grain diameter of the crystal grains is 25 micrometer or more, and a volume fraction of the crystal grain boundary is 14% or less.