Patents by Inventor Keiko Suzuki
Keiko Suzuki has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7514475Abstract: A compound of the formula (I): wherein R1 is a C1-C6 alkyl, an amino, a (C1-C6 alkyl)amino, a di(C1-C6 alkyl)amino or a nitrogen-containing saturated heterocyclic; R2 and R3 are the same or different and are a hydrogen or a C1-C6 alkyl; Arom is an unsubstituted or substituted aryl or an unsubstituted or substituted heteroaryl; wherein the substituted aryl is substituted at 1 to 5 positions and the substituted heteroaryl is substituted at 1 to 3 positions; wherein the heteroaryl is furyl, thiolyl, pyrrolyl, azepinyl, pyrazolyl, imidazolyl, oxazolyl, isoxazolyl, thiazolyl, isothiazolyl, 1,2,3 oxadiazolyl, pyranyl, pyridyl, pyridazinyl, pyrimidinyl, pyrazinyl or quinolyl; and wherein the substituents of the substituted aryl and of the substituted heteroaryl are independently halogen, C1-C6 alkyl, halogeno C1-C6 alkyl, C1-C6 alkoxy, C1-C6 alkylthio, C1-C3 alkylenedioxy, C1-C7 alkanoyl, C2-C7 alkyloxycarbonyl, amino, C1-C7 alkanoylamino, hydroxyl, mercapto, cyano, nitro or carboxyl; A is an ethylene or propyleType: GrantFiled: October 19, 2006Date of Patent: April 7, 2009Assignee: BTG International LimitedInventors: Kazuo Koyama, Shinji Marumoto, Narihiro Toda, Hiroshi Kogen, Keiko Suzuki
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Patent number: 7504393Abstract: A compound of the formula (I): wherein R1 is a C1-C6 alkyl group, an amino group, a (C1-C6 alkyl)amino group, a di(C1-C6 alkyl)amino group or a nitrogen-containing saturated heterocyclic group; R3 is a hydrogen atom or a C1-C6 alkyl group; Arom is an unsubstituted or substituted aryl group or an unsubstituted or substituted heteroaryl group; wherein the substituted aryl group is substituted at 1 to 5 positions and the substituted heteroaryl group is substituted at 1 to 3 positions; and wherein the substituents of the aryl group and of the heteroaryl group are independently selected from the group consisting of halogen atom, C1-C6 alkyl, halogeno C1-C6 alkyl, C1-C6 alkoxy, C1-C6 alkylthio, C1-C3 alkylenedioxy, C1-C7 alkanoyl, C2-C7 alkyloxycarbonyl, amino, C1-C7 alkanoylamino, hydroxyl, mercapto, cyano, nitro and carboxyl; A is a C1-C6 alkylene group; Ra together with R2 is a C2-C3 alkylene group containing a double bond; E is a single bond, an oxygen atom, a sulfur atom or a group of the formula: —NR4—, wType: GrantFiled: October 19, 2006Date of Patent: March 17, 2009Assignee: BTG International LimitedInventors: Kazuo Koyama, Shinji Marumoto, Narihiro Toda, Hiroshi Kogen, Keiko Suzuki
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Patent number: 7504437Abstract: A compound of the formula (I): wherein R1 represents C1–C6 alkyl, amino(C1–C6 alkyl)amino, di(C1–C6 alkyl)amino or a nitrogen-containing saturated heterocyclic; R2 and R3 are the same or different and represent hydrogen or C1–C6 alkyl; Ra represents C1–C6 alkyl or C2–C6 alkenyl or together with R2 represents a C1–C3 alkylene; Arom represents aryl or heteroaryl; A represents a C1–C6 alkylene; E represents a single bond, oxygen, sulfur or R4NR4—, wherein R4 is hydrogen or C1–C7 alkenoyl; X1 and X2 are the same or different and represent oxygen or sulfur; or a pharmacologically acceptable salt or ester thereof. The compound has superior acetylcholinesterase inhibitory action and selective serotonin reuptake inhibitory action, and is useful for treating or preventing Alzheimer's disease, depression, Huntington's chorea, Pick's disease, tardive dyskinesia, compulsive disorders or panic disorders.Type: GrantFiled: July 28, 2003Date of Patent: March 17, 2009Assignee: BTG International LimitedInventors: Kazuo Koyama, Shinji Marumoto, Narihiro Toda, Keiko Suzuki
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Publication number: 20080255095Abstract: A compound of the formula (I): wherein R1 is C1-C6 alkyl, amino, (C1-C6 alkyl)amino, di(C1-C6 alkyl)amino or a nitrogen-containing saturated heterocyclic; R2 and R3 are hydrogen or C1-C6 alkyl; Arom is phenyl, idenyl, napthyl, phenanthrenyl, furyl, thiolyl, pyrrolyl, azepinyl, pyrazolyl, imidazolyl, oxazolyl, isoxazolyl, thiazolyl, isothiazolyl, 1,2,3 oxadiazolyl, pyranyl, pyridyl, pyridazinyl, pyrimidinyl, pyrazinyl or quinolyl; A is C1-C6 alkylene; Ra is hydrogen, C1-C6 alkyl or C2-C6 alkenyl; E is a single bond, oxygen, sulfur or —NR4—, wherein R4 is hydrogen or C1-C7 alkanoyl; X1 and X2 are oxygen or sulfur; or a pharmacologically acceptable salt or ester thereof.Type: ApplicationFiled: June 18, 2007Publication date: October 16, 2008Applicant: BTG INTERNATIONAL LIMITEDInventors: Kazuo Koyama, Shinji Marumoto, Narihiro Toda, Hiroshi Kogen, Keiko Suzuki
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Patent number: 7235399Abstract: The present invention provides a method for obtaining optically active 3-chloro-2-methyl-1,2-propanediol, the method comprising: a first step of letting at least one kind of microorganism or processed product thereof having an ability to leave untouched (R)-3-chloro-2-methyl-1,2-propanediol or (S)-3-chloro-2-methyl-1,2-propanediol in the presence of an enantiomeric 3-chloro-2-methyl-1,2-propanediol mixture act on an enantiomeric 3-chloro-2-methyl-1,2-propanediol mixture; and a second step of recovering the untouched optically active 3-chloro-2-methyl-1,2-propanediol.Type: GrantFiled: January 4, 2005Date of Patent: June 26, 2007Assignee: Daiso Co., Ltd.Inventors: Kouji Nishikawa, Toshio Suzuki, Atsushi Nakagawa, Keiko Suzuki, Satoshi Nakayama
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Publication number: 20070037795Abstract: A compound of the formula (1): wherein R1 is a C1-C6 alkyl, an amino, a (C1-C6 alkyl)amino, a di(C1-C6 alkyl)amino or a nitrogen-containing saturated heterocyclic; R2 and R3 are the same or different and are a hydrogen or a C1-C6 alkyl; Arom is an unsubstituted or substituted aryl or an unsubstituted or substituted heteroaryl; wherein the substituted aryl is substituted at 1 to 5 positions and the substituted heteroaryl is substituted at 1 to 3 positions; wherein the heteroaryl is furyl, thiolyl, pyrrolyl, azepinyl, pyrazolyl, imidazolyl, oxazolyl, isoxazolyl, thiazolyl, isothiazolyl, 1,2,3 oxadiazolyl, pyranyl, pyridyl, pyridazinyl, pyrimidinyl, pyrazinyl or quinolyl; and wherein the substituents of the substituted aryl and of the substituted heteroaryl are independently halogen, C1-C6 alkyl, halogeno C1-C6 alkyl, C1-C6 alkoxy, C1-C6 alkylthio, C1-C3 alkylenedioxy, C1-C7 alkanoyl, C2-C7 alkyloxycarbonyl, amino, C1-C7 alkanoylamino, hydroxyl, mercapto, cyano, nitro or carboxyl; A is an ethylene or propylType: ApplicationFiled: October 19, 2006Publication date: February 15, 2007Applicant: BTG INTERNATIONAL LIMITEDInventors: Kazuo Koyama, Shinji Marumoto, Narihiro Toda, Hiroshi Kogen, Keiko Suzuki
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Publication number: 20070037793Abstract: A compound of the formula (I): wherein R1 is a C1-C6 alkyl group, an amino group, a (C1-C6 alkyl)amino group, a di(C1-C6 alkyl)amino group or a nitrogen-containing saturated heterocyclic group; R3 is a hydrogen atom or a C1-C6 alkyl group; Arom is an unsubstituted or substituted aryl group or an unsubstituted or substituted heteroaryl group; wherein the substituted aryl group is substituted at 1 to 5 positions and the substituted heteroaryl group is substituted at 1 to 3 positions; and wherein the substituents of the aryl group and of the heteroaryl group are independently selected from the group consisting of halogen atom, C1-C6 alkyl, halogeno C1-C6 alkyl, C1-C6 alkoxy, C1-C6 alkylthio, C1-C3 alkylenedioxy, C1-C7 alkanoyl, C2-C7 alkyloxycarbonyl, amino, C1-C7 alkanoylamino, hydroxyl, mercapto, cyano, nitro and carboxyl; A is a C1-C6 alkylene group; Ra together with R2 is a C2-C3 alkylene group containing a double bond; E is a single bond, an oxygen atom, a sulfur atom or a group of the formula: —NR4—,Type: ApplicationFiled: October 19, 2006Publication date: February 15, 2007Applicant: BTG INTERNATIONAL LIMITEDInventors: Kazuo Koyama, Shinji Marumoto, Narihiro Toda, Hiroshi Kogen, Keiko Suzuki
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Publication number: 20060217368Abstract: An object of the present invention is to provide a nerve regenerating drug, an agent for the promotion of neuropoiesis of a neural stem cell, a neuron obtained by culturing a neural stem cell in the presence of the agent for the promotion of neuropoiesis, and a method of the manufacture of the neuron. In order to achieve the object, the invention provides a nerve regenerating drug comprising a substance that inhibits the activity of glycogen synthase kinase-3, as an active ingredient; an agent for the promotion of neuropoiesis of a neural stem cell comprising the substance as an active ingredient; a neuron obtained by culturing a neural stem cell in the presence of the agent for the promotion of neuropoiesis; and a method of the manufacture of the neuron.Type: ApplicationFiled: April 16, 2004Publication date: September 28, 2006Applicant: Kyowa Hakko Kogyo Co., Ltd.Inventors: Tsuyoshi Morishita, Kazuhiro Sakurada, Keiko Suzuki, Shun-ichi Ikeda
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Publication number: 20050153409Abstract: The present invention provides a method for obtaining optically active 3-chloro-2-methyl-1,2-propanediol, the method comprising: a first step of letting at least one kind of microorganism or processed product thereof having an ability to leave untouched (R)-3-chloro-2-methyl-1,2-propanediol or (S)-3-chloro-2-methyl-1,2-propanediol in the presence of an enantiomeric 3-chloro-2-methyl-1,2-propanediol mixture act on an enantiomeric 3-chloro-2-methyl-1,2-propanediol mixture; and a second step of recovering the untouched optically active 3-chloro-2-methyl-1,2-propanediol.Type: ApplicationFiled: January 4, 2005Publication date: July 14, 2005Inventors: Kouji Nishikawa, Toshio Suzuki, Atsushi Nakagawa, Keiko Suzuki, Satoshi Nakayama
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Publication number: 20040067981Abstract: A compound of the formula (I): 1Type: ApplicationFiled: July 28, 2003Publication date: April 8, 2004Applicant: SANKYO COMPANY, LIMITEDInventors: Kazuo Koyama, Shinji Marumoto, Narihiro Toda, Hiroshi Kogen, Keiko Suzuki
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Patent number: 5183824Abstract: An azole derivative represented by the following formula (I): ##STR1## wherein X is a nitrogen atom or CH, Y is an oxygen atom, a sulfur atom, an imino group, a methylimino group or a group represented by .dbd.N.about.O--, Z is one or two halogen atoms, n stands for a number of 1 or 2, the wavy line means that stereochemistry of the double bond is either E or Z; or an acid adduct thereof.They exhibit strong antifungal activities and are very useful in the therapy for fungus diseases.Also disclosed is an antifungal drug containing said compound as an active ingredient.Type: GrantFiled: February 3, 1992Date of Patent: February 2, 1993Assignee: Kao CorporationInventors: Kimihiko Hori, Akira Sakaguchi, Koichi Ishida, Tomoko Nomura, Keiko Suzuki, Shuichi Tsuchiya
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Patent number: 5178979Abstract: An image transfer type recording method for forming a visible image on a developer medium comprising a base sheet, a thermoplastic resin layer, and a developer material layer which is color-reactable with a chromogenic material laminated in this order, and transferring the visible image on the developer medium to any type of image supporting medium, comprising the steps of forming the visible image on the developer material layer through a color-reaction between the developer material and the chromogenic material, providing an adhesive layer on the developer material layer, superposing the developer material layer and the image supporting medium under pressure and heat to fixedly transfer the developer material layer having the visible image thereon to the image supporting medium, and peeling off only the substrate of the developer medium.Type: GrantFiled: October 30, 1990Date of Patent: January 12, 1993Assignee: Brother Kogyo Kabushiki KaishaInventors: Shunichi Higashiyama, Keiko Suzuki
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Patent number: 5110826Abstract: An azole derivative represented by the following formula (I): ##STR1## wherein X is a nitrogen atom or CH, Y is an oxygen atom, a sulfur atom, an imino group, a methylimino group or a group represented by .dbd.N O--, Z is one or two halogen atoms, in stands for a number of 1 to 2, the wavy line means that stereochemistry of the double bond is either E or Z; or an acid adduct thereof.They exhibit strong antifungal activities and are very useful in the therapy for fungus diseases.Also disclosed is an antifungal drug containing said compound as an active ingredient.Type: GrantFiled: November 7, 1990Date of Patent: May 5, 1992Assignee: Kao CorporationInventors: Kimihiko Hori, Akira Sakaguchi, Koichi Ishida, Tomoko Nomura, Keiko Suzuki, Shuichi Tsuchiya
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Patent number: 5081484Abstract: An image recording medium is provided with an identifying index indicative of whether or not one side of the image recording medium is a front side coated with developing agent. In another image recording medium coated with developing agent, electrical resistance material is coated on at least one side of the image recording medium. In a detecting device for the another image recording medium, an electrode unit is provided for measuring electric conductivity of one side of the image recording medium. A control unit is connected to the electrode unit for identifying the image recording medium on the basis of the electric conductivity measured by the electrode unit. In another detecting device, a light emitting unit emits light with which at least one of front and back sides of an image recording medium is illuminated. A light receiving unit receives light reflected from the at least one side of the image recording medium.Type: GrantFiled: July 19, 1990Date of Patent: January 14, 1992Assignee: Brother Kogyo Kabushiki KaishaInventors: Takashi Nakata, Shunichi Higashiyama, Takashi Tomizawa, Satoru Kuwabara, Jun Sakai, Mitsuru Ohta, Hiroshi Kawahara, Keiko Suzuki
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Patent number: 5059266Abstract: An apparatus and a method for forming a three-dimensional article with photosetting or thermosetting material on the basis of a three-dimensional information on the article by means of an ink jet method. The material is jetted from at least one ink jet head to a stage and laminated thereon. The laminated material is exposed to light by a light source to be cured. In this process, a jetting direction of the material from the ink jet head to the stage and/or a jetting amount of the material jetted from the ink jet head is changed in accordance with the information by a control unit, thereby forming a solid article having a desired three-dimensional shape.Type: GrantFiled: May 23, 1990Date of Patent: October 22, 1991Assignee: Brother Kogyo Kabushiki KaishaInventors: Mitsuo Yamane, Takashi Kawaguchi, Shigeru Kagayama, Shunichi Higashiyama, Keiko Suzuki, Jun Sakai, Mikio Imaeda, Kouji Inaishi
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Patent number: 5043314Abstract: A recording medium which enables formation of an image on any desired substrate is disclosed, which comprises a support having provided thereon at least a color developer capable of color-forming reaction with a dye precursor, and an adhesive such as heat-sensitive adhesives, tackifying composition, etc.Type: GrantFiled: July 10, 1990Date of Patent: August 27, 1991Assignee: Brother Kogyo Kabushiki KaishaInventors: Koji Suzuki, Jun Sakai, Shunichi Higashiyama, Keiko Suzuki, Mikio Imaeda
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Patent number: 5019475Abstract: A recording medium enabling formation of an image on any desired material is disclosed. The recording medium comprises a base sheet, a thermoplastic resin layer formed on at least one side of the base sheet, and a color developer layer formed on the thermoplastic resin layer and capable of color development by reaction with a dye precursor.Type: GrantFiled: March 22, 1990Date of Patent: May 28, 1991Assignee: Brother Kogyo Kabushiki KaishaInventors: Shunichi Higashiyama, Keiko Suzuki
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Patent number: 4971886Abstract: A recording medium comprising a planar substrate, and a layer of microcapsules carried by the planar substrate, each of the microcapsules containing a photosensitive material whose hardness varies upon exposure to a radiation, and a heat-sensitive chromogenic material which produces a color at a temperature higher than a room temperature.Type: GrantFiled: August 3, 1988Date of Patent: November 20, 1990Assignee: Brother Kogyo Kabushiki KaishaInventor: Keiko Suzuki
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Patent number: 4905036Abstract: A process and system for forming images on a recording sheet, according to source image information as provided on an original, wherein a pressure-sensitive photosensitive sheet is image-wise exposed to a radiation, to form thereon latent images corresponding to the source image information, and a pressure is applied to the image-wise exposed photosensitive sheet, to cause a chemical reaction and thereby develop the latent images into visible images on the recording sheet. The thus pressurized recording sheet is heated so that the chemical reaction is promoted to thereby increase a density of the visible images.Type: GrantFiled: October 26, 1987Date of Patent: February 27, 1990Assignee: Brother Kogyo Kabushiki KaishaInventors: Yuji Asano, Jun Sakai, Yumio Matsumoto, Osamu Takagi, Akira Sago, Kiyoharu Hayakawa, Masashi Ueda, Yukichi Sawaki, Keiko Suzuki
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Patent number: 4841338Abstract: The photocopying is usually made by the chemical reaction with the developing agents on photosensitive sheet or on separate developing agents layer. However, any type of sheet of paper such as mail card, card stock or the like can be photocopied in such manner that the photocopied image formed on photosensitive sheet is adhered to the sheet of paper by using an adhesive coater. Using this method, the sheets of paper are double folded after adhering.Further, instead of adhering the photosensitive sheet to the sheet of paper, the image can also be formed on the sheet of paper by coating developing agents thereon for chemical reaction with the photosensitive sheet. Thus the thickness of paper can be reduced to a single sheet of paper.Type: GrantFiled: March 25, 1988Date of Patent: June 20, 1989Assignee: Brother Kogyo Kabushiki KaishaInventor: Keiko Suzuki