Abstract: The invention provides compositions and methods for treating diseases such as cancer. The invention also relates to a method of administering a chimeric antigen receptor (CAR) therapy and an additional therapeutic agent, e.g., one or more cytokine molecules, e.g., a virus comprising a nucleic acid molecule encoding one or more cytokine molecules.

Abstract: An oxygen absorbing resin composition containing a polyolefin, an iron powder, titanium oxide, and calcium oxide, a content of the iron powder being from 10 to 50 mass % in the oxygen absorbing resin composition, a mass ratio of the titanium oxide to the iron powder [titanium oxide/iron powder] being from 0.1 to 0.5, and a mass ratio of the calcium oxide to the iron powder [calcium oxide/iron powder] being from 0.1 to 0.5.

Abstract: A sensor includes: a sensor section including a conductive structure made up of a three-dimensionally continuous unit lattices, each including a plurality of columnar beams; and output connectors that output a resistance value of the sensor section, the resistance value changing at least when the conductive structure is compressed by an external force. A method for manufacturing a sensor includes forming the sensor section by stacking using a 3D printer. The sensor and method for manufacturing the sensor enable the adjustment of the repulsive force against compression to an input member and thus appropriately setting the change in resistance value against external force according to the device, in which the sensor is to be incorporated and the mode of use.

Abstract: A shutoff system that shuts off a current path includes a shunt resistor provided in the current path, and a pyroswitch that includes an internal resistor and shuts off the current path by performing detonation in accordance with a current that flows in the internal resistor. The shunt resistor and the internal resistor are connected in parallel to each other.

Abstract: A binder that hardly causes gelation even when mixed with a positive electrode active material containing nickel, and has sufficient adhesiveness in a small amount. The binder contains a vinylidene fluoride polymer, the vinylidene fluoride polymer includes a structural unit derived from vinylidene fluoride and two or more kinds of structural units having a carboxy group, and a viscosity ratio of slurry determined by a specific method is 100% or less.

Abstract: A first difference spectrum between a sample spectrum of a test sample and a reference spectrum of a reference sample of which concentration of a specific component is lower than the test sample is calculated (S10); using multiple reference spectra acquired by measuring the reference sample for multiple times, a difference spectrum having a shape similar to the first difference spectrum is selected from multiple difference spectra between two reference spectra (S20); a second difference spectrum based on the selected difference spectrum and the first difference spectrum is calculated (S30); and a shape of an absorption band of the specific component is acquired from the second difference spectrum to determine the concentration of the specific component (S40).

Abstract: An object is to provide a binder that hardly causes gelation even when mixed with a positive electrode active material containing nickel, and has sufficient adhesiveness in a small amount. The binder that solves the issue described above contains a vinylidene fluoride polymer, and the vinylidene fluoride polymer includes a structural unit derived from vinylidene fluoride and two or more kinds of structural units represented by a specific structural formula.

Abstract: There is provided an oxygen scavenger composition comprising iron, a metal salt, and water, wherein the content of water per unit surface area of the iron present on the surface of the iron, [the content of water present on the surface of the iron (g)/{the content of the iron (g)×the specific surface area of the iron (m2/g)}], is more than 2.00 g/m2 and 3.50 g/m2 or less.

Abstract: There is provided an oxygen scavenger composition comprising iron, a metal salt and water, wherein the content of water per unit surface area of the iron present on the surface of the iron, [the content of water present on the surface of the iron] (g)/{the content of the iron (g)×the specific surface area of the iron (m2/g)}], is 0.60 g/m2 or more and 2.00 g/m2 or less.

Abstract: The present invention provides an immunoassay method for detecting a protein with an isoelectric point of 9.5 or higher, comprising a step of bringing a sample containing the protein with an isoelectric point of 9.5 or higher into contact with a glass material in the presence of a cationic substance, and an immunochromatography kit for detecting a protein with an isoelectric point of 9.5 or higher, comprising a specimen diluent and an immunochromatography test strip.

Abstract: Provided is a sensor that is able to efficiently identify a variety of motions made by a user. The sensor includes: a structure body configured to be deformable by an external force; an electrode configured to be disposed at an arbitrary position of the structure body; a determination unit configured to determine a contact state of an object with the structure body based on a change in impedance measured using the electrode; and an output unit configured to output a signal based on the contact state of the object with the structure body to an external device.

Abstract: The present invention provides an immunoassay method for assaying SARS-CoV-2 in a biological sample, including using two types of monoclonal antibodies or antibody fragments thereof that bind to a peptide fragment having 30 or less consecutive amino acids in a nucleocapsid protein of SARS-CoV-2, wherein the two types of monoclonal antibodies or antibody fragments thereof recognize different epitopes

Abstract: Provided is an oxygen absorber containing: a liquid oligomer of an unsaturated hydrocarbon; a transition metal catalyst; a carrier supporting the liquid oligomer of the unsaturated hydrocarbon and the transition metal catalyst; granular activated carbon; and crystalline thermoplastic resin particles. In an analysis curve derived by subjecting the crystalline thermoplastic resin particles and the granular activated carbon to a pyrolysis-gas chromatography analysis under a pyrolysis condition of 600° C., a ratio [Cref/Pref] of a peak area (Cref) of a decomposition product of a low molecular weight component of the crystalline thermoplastic resin particles adsorbed on the granular activated carbon per unit mass of the activated carbon to a peak area (Pref) of the crystalline thermoplastic resin particle decomposition product per unit mass of the crystalline thermoplastic resin particles is 0.20 or less.

Abstract: Provided is an oxygen absorber including an unsaturated group-containing liquid oligomer, an oxygen absorption-promoting substance, a carrier supporting the unsaturated group-containing liquid oligomer and the oxygen absorption-promoting substance, gas-absorbing inorganic particles, and activated carbon. An amount of the unsaturated group-containing liquid oligomer adsorbed on the gas-absorbing inorganic particles is 6.5 parts by mass or less per 100 parts by mass of the gas-absorbing inorganic particles.

Abstract: The present disclosure provides anti-CCR4 chimeric antigen receptors (CARs) and compositions and methods for modified immune cells or precursors thereof (e.g., modified T cells) comprising anti-CCR4 CARs. Also provided are methods of using the anti-CCR4 CAR-expressing cells to treat cancer and T cell-depleting systems for use in combination with anti-CCR4 CAR T cell therapy.

Abstract: An integrated circuit according to one or more embodiments may include a terminal to which an impedance element and a power supply having a predetermined potential can be connected. The integrated circuit may be configured to change a potential of one of electrodes of the impedance element connected to the terminal, detect a change in electrical characteristics of the terminal based on characteristics of the impedance element when the potential of the one electrode of the impedance element is changed, to determine a setting condition among a plurality of setting conditions that are used for an operation of the integrated circuit, store the setting condition in a storage, and use the setting condition stored in the storage for the operation of the integrated circuit.

Abstract: An oxygen absorbing resin composition containing a polyolefin, an iron powder, titanium oxide, and calcium oxide, a content of the iron powder being from 10 to 50 mass % in the oxygen absorbing resin composition, a mass ratio of the titanium oxide to the iron powder [titanium oxide/iron powder] being from 0.1 to 0.5, and a mass ratio of the calcium oxide to the iron powder [calcium oxide/iron powder] being from 0.1 to 0.5.

Abstract: An object is to provide a resin composition excellent in dry adhesion to both a positive electrode and a negative electrode. Provided is a resin composition to solve the above issue, which contains a vinylidene fluoride copolymer containing: 73.7 mass% or more and 96.9 mass% or less of a constituent unit derived from vinylidene fluoride; 0.1 mass% or more and 1.3 mass% or less of a constituent unit containing a carboxy group; and 3 mass% or more and 25 mass% or less of an other constituent unit which does not contain a carboxy group and is derived from a compound copolymerizable with vinylidene fluoride, with the proviso that a total amount of the constituent units constituting the vinylidene fluoride is taken as 100 mass%. A solution obtained by dissolving 4 g of the vinylidene fluoride copolymer in 1 L of N,N-dimethylformamide has an intrinsic viscosity at 30° C. of 0.5 dL/g or more and 3 dL/g or less.