Abstract: A boring bit such as for horizontal directional drilling is provided which includes a hard faced layer that is preferably made by a laser cladding bead. The laser clad bead may be applied in some regions to a greater extent and in other regions to a lighter extent and with thicker coverage or longer regions of application in different regions of the boring bit. Additionally, circumferential segments of the hard faced layer bead may be applied to impart a spiral path on the outer periphery of the boring bit which may be overlapped upon more general hard faced layer application. Further, the hard faced layer may be applied in substantially complete coverage over carbide insert teeth that are embedded within the steel base of the boring bit body.

Abstract: A concave section for a harvester includes a concave body having an upstream side, a downstream side, a leading end and a trailing end. The concave body defines an arcuate crop engagement face facing radially inwardly. A plurality of crop passage openings are defined through the arcuate crop engagement face. A cover is configured to at least partially cover at least some of the crop passage openings. The cover is carried by the concave body and is movable thereon between at least two different positions to adjust a degree of openness of at least some of the crop passage openings.

Abstract: A concave section for a harvester includes a concave body having an upstream side, a downstream side, a leading end and a trailing end. The concave body defines an arcuate crop engagement face facing radially inwardly. A plurality of crop passage openings are defined through the arcuate crop engagement face. A cover is configured to at least partially cover at least some of the crop passage openings. The cover is carried by the concave body and is movable thereon between at least two different positions to adjust a degree of openness of at least some of the crop passage openings.

Abstract: A boring bit or other component for horizontal directional drilling is provided which includes a hard faced layer that is preferably made by a laser cladding bead. A subsequent or post heat treatment is applied to modify the heat affected zone (HAZ) to eliminate or reduce the hard brittle regions and/or softer regions in the base iron or steel material of the HAZ. Further, the hard faced layer may be applied in combination with carbide insert teeth that are embedded within the steel base of the boring bit body, such as by press fitting.

Abstract: A pharmaceutical composition, comprising a therapeutically effective amount of an active pharmaceutical ingredient (API) compound represented by the following structural formula at least one acidifying agent; and a vehicle base comprising at least one pharmaceutically acceptable non-aqueous solvent. Values and preferred values of the variables in structural formula (I) are defined herein.

Abstract: A pharmaceutical composition, comprising a therapeutically effective amount of an active pharmaceutical ingredient (API) compound represented by the following structural formula at least one acidifying agent; and a vehicle base comprising at least one pharmaceutically acceptable non-aqueous solvent. Values and preferred values of the variables in structural formula (I) are defined herein.

Abstract: A concave section for a harvester includes a concave body having an upstream side, a downstream side, a leading end and a trailing end. The concave body defines an arcuate crop engagement face facing radially inwardly. A plurality of crop passage openings are defined through the arcuate crop engagement face. A cover is configured to at least partially cover at least some of the crop passage openings. The cover is carried by the concave body and is movable thereon between at least two different positions to adjust a degree of openness of at least some of the crop passage openings.

Abstract: A knifeback for a sickle bar assembly that supports individual sickle sections is provided. The knifeback includes a bar having a channel formed longitudinally therein. Mounting holes extend through the bar and into the channel to facilitate mounting of sickle sections. The channel may provide strength and rigidity, provide structure for engaging sickle fastening bolts to prevent rotation thereof, and/or may be used to increase support and rigidity of a splicing member.

Abstract: A concave section for a harvester includes a concave body having an upstream side, a downstream side, a leading end and a trailing end. The concave body defines an arcuate crop engagement face facing radially inwardly. A plurality of crop passage openings are defined through the arcuate crop engagement face. A cover is configured to at least partially cover at least some of the crop passage openings. The cover is carried by the concave body and is movable thereon between at least two different positions to adjust a degree of openness of at least some of the crop passage openings.

Abstract: Laser shock peening is applied to a harvester component for an agricultural wear application that for example may be any of the following components: a knifeback, a knifehead, a knifeback connecting strap, a straw chopper, a sickle section, stalk chopper, a bedknife, a sod cutter knife, a net wrap knife or a combine concave component. The laser shock peening may be selectively applied. For example, laser shock peening can be applied in regions of drive ends of harvester components, and/or in regions proximate fastener holes of such harvester components.

Abstract: Compositions are provided comprising recombinant variants of the human clotting Factor Xa. Such compositions include a wide variety of isoforms and post-translational modifications of FXa and are useful for treating subjects in need of hemostasis.

Abstract: A pharmaceutical composition, comprising a therapeutically effective amount of an active pharmaceutical ingredient (API) compound represented by the following structural formula at least one acidifying agent; and a vehicle base comprising at least one pharmaceutically acceptable non-aqueous solvent. Values and preferred values of the variables in structural formula (I) are defined herein.

Abstract: A knifeback for a sickle bar assembly that supports individual sickle sections is provided. The knifeback includes a bar having a channel formed longitudinally therein. Mounting holes extend through the bar and into the channel to facilitate mounting of sickle sections. The channel may provide strength and rigidity, provide structure for engaging sickle fastening bolts to prevent rotation thereof, and/or may be used to increase support and rigidity of a splicing member.

Abstract: A boring bit or other component for horizontal directional drilling is provided which includes a hard faced layer that is preferably made by a laser cladding bead. A subsequent or post heat treatment is applied to modify the heat affected zone (HAZ) to eliminate or reduce the hard brittle regions and/or softer regions in the base iron or steel material of the HAZ. Further, the hard faced layer may be applied in combination with carbide insert teeth that are embedded within the steel base of the boring bit body, such as by press fitting.

Abstract: A boring bit such as for horizontal directional drilling is provided which includes a hard faced layer that is preferably made by a laser cladding bead. The laser clad bead may be applied in some regions to a greater extent and in other regions to a lighter extent and with thicker coverage or longer regions of application in different regions of the boring bit. Additionally, circumferential segments of the hard faced layer bead may be applied to impart a spiral path on the outer periphery of the boring bit which may be overlapped upon more general hard faced layer application. Further, the hard faced layer may be applied in substantially complete coverage over carbide insert teeth that are embedded within the steel base of the boring bit body.

Abstract: Compositions are provided comprising recombinant variants of the human clotting Factor Xa. Such compositions include a wide variety of isoforms and post-translational modifications of FXa and are useful for treating subjects in need of hemostasis.

Abstract: A sickle cutting section is provided. The sickle cutting section comprises a plate having a base material of a first hardness. The plate extends forwardly from a mounting portion to a front tip. A serrated cutting edge extends at least partially between the front tip and the mounting portion. A clad material is of a second hardness that is harder than the first hardness and is deposited along the base material at least partially along the serrated cutting edge.

Abstract: A concave section for a harvester is provided. The concave section includes a concave body having an upstream side, a downstream side, a leading end and a trailing end. The concave body defines an arcuate crop engagement face facing radially inwardly. A plurality of crop passage openings are defined through the arcuate crop engagement face. A cover is configured to at least partially cover at least some of the crop passage openings. The cover is carried by the concave body and is movable thereon between at least two different positions to adjust a degree of openness of at least some of the crop passage openings.

Abstract: An agricultural cutting blade has top and bottom surfaces and mounting apertures extending through top and bottom surfaces. A cutting edge support surface (e.g. that may be a flat, pointed or rounded) is formed on the cutting blade body with the cutting edge support extending along a side of the cutting blade body transversely between the top and bottom surfaces. A clad material deposited upon the cutting edge support such as by laser cladding process. The clad material can be built up, that is layered in partial or full overlapping relation to provide at least 2 and often more than 4 layers of clad material at one or more locations. A cutting edge provided by the clad material that may be a ground surface into a laser clad bead.

Abstract: A pharmaceutical composition, comprising a therapeutically effective amount of an active pharmaceutical ingredient (API) compound represented by the following structural formula at least one acidifying agent; and a vehicle base comprising at least one pharmaceutically acceptable non-aqueous solvent. Values and preferred values of the variables in structural formula (I) are defined herein.