Patents by Inventor Keith D. Allen

Keith D. Allen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20030106083
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a RPTPB gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: December 4, 2001
    Publication date: June 5, 2003
    Inventor: Keith D. Allen
  • Publication number: 20030093823
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a limulus clotting factor protease-like gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: July 10, 2001
    Publication date: May 15, 2003
    Inventor: Keith D. Allen
  • Publication number: 20030093824
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in an SPC6 serine protease gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: June 25, 2002
    Publication date: May 15, 2003
    Inventor: Keith D. Allen
  • Publication number: 20030093825
    Abstract: The present invention relates to compositions and methods relating to the characterization and function of PNR. Specifically, the present invention provides transgenic animals comprising disruptions in a PNR gene and methods of treating diseases conditions, such as schizophrenia. The present invention further relates to agents that modulate PNR and methods of screening for agents that modulate PNR for the treatment of diseases and conditions such as schizophrenia.
    Type: Application
    Filed: June 25, 2002
    Publication date: May 15, 2003
    Inventor: Keith D. Allen
  • Publication number: 20030079243
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a TRP6 gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: December 4, 2001
    Publication date: April 24, 2003
    Inventor: Keith D. Allen
  • Publication number: 20030066098
    Abstract: The present invention relates to compositions and methods relating to the characterization of gene function. More particularly, the present invention relates to the role of secreted protein genes involved in neurobiological disorders, and in particular, depression. In addition, the present invention provides transgenic mice comprising mutations in a secreted protein gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions, including depression.
    Type: Application
    Filed: November 5, 2001
    Publication date: April 3, 2003
    Inventors: Russell Phillips, Thadd C. Reeder, Keith D. Allen
  • Publication number: 20030051268
    Abstract: The present invention relates to compositions and methods relating to the characterization and function of CYT28. Specifically, the present invention provides transgenic animals comprising disruptions in a CYT28 gene and methods of treating diseases conditions, such as pain. The present invention further relates to agents that modulate CYT28 and methods of screening for agents that modulate CYT28 for the treatment of diseases and conditions such as pain.
    Type: Application
    Filed: June 24, 2002
    Publication date: March 13, 2003
    Inventor: Keith D. Allen
  • Publication number: 20030046719
    Abstract: The present invention relates to compositions, including transgenic and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a PPAR gene. The present invention also provides methods for identifying agents that modulate PPAR expression and function, useful models, and potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: June 24, 2002
    Publication date: March 6, 2003
    Inventors: Keith D. Allen, Catherine Guenther, Russell Phillips
  • Publication number: 20030033625
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a CLCN4 gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: March 28, 2002
    Publication date: February 13, 2003
    Inventor: Keith D. Allen
  • Publication number: 20030033624
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in an adrenomedullin receptor gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: July 6, 2001
    Publication date: February 13, 2003
    Inventor: Keith D. Allen
  • Publication number: 20030023999
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a GNB1 gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: March 28, 2002
    Publication date: January 30, 2003
    Inventor: Keith D. Allen
  • Publication number: 20030018988
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in an mGluR7 gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: March 28, 2002
    Publication date: January 23, 2003
    Inventors: Keith D. Allen, Russell Phillips
  • Publication number: 20030014772
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a MSK2 gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: March 28, 2002
    Publication date: January 16, 2003
    Inventor: Keith D. Allen
  • Publication number: 20030014769
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a GPCR-like transmembrane protein. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: March 28, 2002
    Publication date: January 16, 2003
    Inventors: Keith D. Allen, William Matthews, Mark Moore
  • Publication number: 20030009778
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a TSH-R gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: October 26, 2001
    Publication date: January 9, 2003
    Inventor: Keith D. Allen
  • Publication number: 20030009780
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a 5-HT5B receptor gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: March 28, 2002
    Publication date: January 9, 2003
    Inventor: Keith D. Allen
  • Publication number: 20030009781
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a Kir3.3 gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: March 28, 2002
    Publication date: January 9, 2003
    Inventor: Keith D. Allen
  • Publication number: 20030005476
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a delta-opioid receptor gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: March 28, 2002
    Publication date: January 2, 2003
    Inventor: Keith D. Allen
  • Publication number: 20030005475
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in an acylphosphatase gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: March 28, 2002
    Publication date: January 2, 2003
    Inventor: Keith D. Allen
  • Publication number: 20020194636
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a PKDL2 gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: December 4, 2001
    Publication date: December 19, 2002
    Inventor: Keith D. Allen