Patents by Inventor Keith D. Allen

Keith D. Allen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20020184657
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a glucocorticoid-induced receptor gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: July 10, 2001
    Publication date: December 5, 2002
    Inventor: Keith D. Allen
  • Publication number: 20020174450
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in the CASH gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: December 4, 2001
    Publication date: November 21, 2002
    Inventors: Keith D. Allen, Michael W. Leviten
  • Publication number: 20020162133
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in an mGluR8 gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: July 6, 2001
    Publication date: October 31, 2002
    Inventor: Keith D. Allen
  • Publication number: 20020152493
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a PTP36 gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: December 4, 2001
    Publication date: October 17, 2002
    Inventor: Keith D. Allen
  • Publication number: 20020152492
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a NOR1 gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: December 4, 2001
    Publication date: October 17, 2002
    Inventors: Catherine Guenther, Keith D. Allen
  • Publication number: 20020148001
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a CRFR2 gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: July 6, 2001
    Publication date: October 10, 2002
    Inventor: Keith D. Allen
  • Publication number: 20020144300
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a glucagon receptor gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions. The present invention also relates to diabetes and diabetic condition, as it demonstrates the role of the glucagon receptor in diabetes and diabetic conditions. The present invention further relates to weight gain and weight related conditions, such as obesity, and demonstrates the role of the glucagon receptor in weight gain and weight related conditions, such as obesity.
    Type: Application
    Filed: December 5, 2001
    Publication date: October 3, 2002
    Inventors: Keith D. Allen, Mark Moore, William Matthews
  • Publication number: 20020133843
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in an ACTHR gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: December 11, 2001
    Publication date: September 19, 2002
    Inventors: Keith D. Allen, William Matthews, Mark Moore
  • Publication number: 20020133839
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a Kir2.3 gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: November 15, 2001
    Publication date: September 19, 2002
    Inventor: Keith D. Allen
  • Publication number: 20020129396
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a CX2 gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: July 6, 2001
    Publication date: September 12, 2002
    Inventors: Keith D. Allen, Qin Zhang
  • Publication number: 20020129397
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a BSMAP gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: December 11, 2001
    Publication date: September 12, 2002
    Inventor: Keith D. Allen
  • Publication number: 20020120951
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in an FPR-RS4 gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: December 4, 2001
    Publication date: August 29, 2002
    Inventors: Keith D. Allen, Mark Moore, William Matthews
  • Publication number: 20020116729
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a NTTP1 gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: December 4, 2001
    Publication date: August 22, 2002
    Inventor: Keith D. Allen
  • Publication number: 20020116727
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a chemokine receptor 9A gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: July 10, 2001
    Publication date: August 22, 2002
    Inventor: Keith D. Allen
  • Publication number: 20020116728
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a Kir5.1 gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: December 4, 2001
    Publication date: August 22, 2002
    Inventor: Keith D. Allen
  • Publication number: 20020116731
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in the LXRB gene. Such transgenic mice are useful as models for disease, such as diabetes. The present invention is also directed to identifying agents that modulate LXRB gene function, and as potential treatments for various disease states and disease conditions, including diabetes.
    Type: Application
    Filed: December 10, 2001
    Publication date: August 22, 2002
    Inventors: Keith D. Allen, Catherine Guenther, Russell Phillips, Qin Zhang, Helene Baribault
  • Publication number: 20020116730
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a PERK gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: November 7, 2001
    Publication date: August 22, 2002
    Inventors: Keith D. Allen, Michael V. Wiles
  • Publication number: 20020112255
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in an intestinal alkaline phosphatase gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: July 6, 2001
    Publication date: August 15, 2002
    Inventor: Keith D. Allen
  • Publication number: 20020112256
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in proliferator-activated receptors. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: December 11, 2001
    Publication date: August 15, 2002
    Inventors: Keith D. Allen, Catherine Guenther, Russell Phillips
  • Publication number: 20020088018
    Abstract: The present invention relates to transgenic animals, as well as compositions and methods relating to the characterization of gene function. Specifically, the present invention provides transgenic mice comprising mutations in a MAS receptor gene. Such transgenic mice are useful as models for disease and for identifying agents that modulate gene expression and gene function, and as potential treatments for various disease states and disease conditions.
    Type: Application
    Filed: July 6, 2001
    Publication date: July 4, 2002
    Inventor: Keith D. Allen