Patents by Inventor Keith Graham

Keith Graham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11339157
    Abstract: Compounds of formula (I) processes for their production and their use as pharmaceuticals.
    Type: Grant
    Filed: October 23, 2018
    Date of Patent: May 24, 2022
    Assignees: Bayer Aktiengesellschaft, Bayer Pharma Aktiengesellschaft, Dana-Farber Cancer Institute, Inc., The Broad Institute, Inc.
    Inventors: Stephan Siegel, Franziska Siegel, Volker Schulze, Markus Berger, Keith Graham, Ulrich Klar, Knut Eis, Detlev Sülzle, Ulf Bömer, Daniel Korr, Kirstin Petersen, Ursula Mönning, Uwe Eberspächer, Dieter Moosmayer, Matthew Meyerson, Heidi Greulich, Bethany Kaplan, Hassan Youssef Harb, Phi Manh Dinh
  • Patent number: 10856707
    Abstract: A sheet product roll holder may include a support arm, a spindle, a flowable material container, and an automated flowable material dispensing mechanism. The support arm may define a first longitudinal axis. The spindle may be coupled to the support arm and define a second longitudinal axis extending transverse to the first longitudinal axis, and the spindle may be configured to rotatably support a roll of sheet product thereon. The flowable material container may be positioned at least partially within the spindle and define a third longitudinal axis extending coaxially with the second longitudinal axis, and the flowable material container may include a container body and a volume of a flowable material positioned within the container body. The automated flowable material dispensing mechanism may be positioned at least partially within the support arm and configured to dispense the flowable material from the flowable material container.
    Type: Grant
    Filed: June 28, 2019
    Date of Patent: December 8, 2020
    Assignee: GPCP IP HOLDINGS LLC
    Inventors: Eric Paul Peterson, Ryan Andersen, Jacob Edward Malesky, Jon Charles Alling, Gordon Keith Graham, III
  • Publication number: 20200216439
    Abstract: Compounds of formula (I) as described herein, processes for their production and their use as pharmaceuticals.
    Type: Application
    Filed: December 12, 2016
    Publication date: July 9, 2020
    Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Keith GRAHAM, Ulrich KLAR, Hans BRIEM, Gerhard SIEMEISTER, Ursula MÖNNING, Franz VON NUSSBAUM
  • Patent number: 10667548
    Abstract: A method of manufacture of a breadcrumb coating for a food product provides a crumb with an extremely low moisture content without the need for substantial energy input. The method achieves such very low moisture content without significant adverse effect on product quality.
    Type: Grant
    Filed: April 19, 2016
    Date of Patent: June 2, 2020
    Assignee: Crisp Sensation Holding S.A.
    Inventors: Keith Graham Pickford, Kees van Doorn, Carry Reichgelt
  • Publication number: 20200015638
    Abstract: A sheet product roll holder may include a support arm, a spindle, a flowable material container, and an automated flowable material dispensing mechanism. The support arm may define a first longitudinal axis. The spindle may be coupled to the support arm and define a second longitudinal axis extending transverse to the first longitudinal axis, and the spindle may be configured to rotatably support a roll of sheet product thereon. The flowable material container may be positioned at least partially within the spindle and define a third longitudinal axis extending coaxially with the second longitudinal axis, and the flowable material container may include a container body and a volume of a flowable material positioned within the container body. The automated flowable material dispensing mechanism may be positioned at least partially within the support arm and configured to dispense the flowable material from the flowable material container.
    Type: Application
    Filed: June 28, 2019
    Publication date: January 16, 2020
    Inventors: Eric Paul Peterson, Ryan Andersen, Jacob Edward Malesky, Jon Charles Alling, Gordon Keith Graham, III
  • Patent number: 10487092
    Abstract: The present invention relates to substituted pyrazolopyridinamine compounds of general formula (I) as described and defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyperproliferative and/or angiogenesis disorder, inflammatory disease and disease associated with inflammatory pain, as a sole agent or in combination with other active ingredients.
    Type: Grant
    Filed: December 14, 2015
    Date of Patent: November 26, 2019
    Assignee: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Anja Giese, Ulrich Klar, Keith Graham, Georg Kettschau, Detlev Sülzle, Philip Lienau, Kirstin Petersen, Julien LeFranc, Nicole Schmidt
  • Patent number: 10428044
    Abstract: Compounds of formula (I) which are inhibitors of Bub1 kinase, processes for their production and their use as pharmaceuticals.
    Type: Grant
    Filed: June 17, 2015
    Date of Patent: October 1, 2019
    Assignee: Bayer Pharma Aktiengesellschaft
    Inventors: Keith Graham, Ulrich Klar, Hans Briem, Marion Hitchcock, Lars Bärfacker, Knut Eis, Volker Schulze, Gerhard Siemeister, Wilhelm Bone, Jens Schröder, Simon Holton, Philip Lienau, René Tempel, Helmut Sonnenschein, Jozsef Bálint, Heinz Graubaum
  • Patent number: 10428063
    Abstract: Compound of formula (I), processes for their production and their use as pharmaceuticals.
    Type: Grant
    Filed: January 25, 2016
    Date of Patent: October 1, 2019
    Assignee: Bayer Pharma Aktiengesellschaft
    Inventors: Keith Graham, Ulrich Klar, Hans Briem, Volker Schulze, Gerhard Siemeister, Philip Lienau, René Tempel, Jozsef Bálint
  • Patent number: 10375983
    Abstract: A food product comprising a substrate of pieces of meat, poultry, fish, vegetable, fruit or dairy food and an aqueous composition coating the substrate provides improved performance, particularly for microwave cooking of reheating of the food product. The aqueous coating composition includes a mixture consisting of by dry weight: cellulose gum 15-35% modified starch 15-50% hydrocolloid ?20-30%, wherein the hydrocolloid is selected from the group consisting of xanthan gum, carrageenan gum, guar gum and mixtures thereof, and proteinaceous component 10-20%; wherein the percentages of the ingredients are selected from the ranges quoted to total 100%; and wherein the aqueous coating composition does not contain any substantial amount of polydextrose.
    Type: Grant
    Filed: April 30, 2014
    Date of Patent: August 13, 2019
    Assignee: Crisp Sensation Holding B.V.
    Inventor: Keith Graham Pickford
  • Patent number: 10308629
    Abstract: Compounds of formula (I) as described herein, processes for their production and their use as pharmaceuticals.
    Type: Grant
    Filed: August 1, 2016
    Date of Patent: June 4, 2019
    Assignee: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Keith Graham, Ulrich Klar, Hans Briem, Gerhard Siemeister, Ursula Mönning
  • Patent number: 10227299
    Abstract: Compounds of formula (I) as described herein processes for their production and their use as anti-cancer agents.
    Type: Grant
    Filed: June 14, 2016
    Date of Patent: March 12, 2019
    Assignee: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Keith Graham, Ulrich Klar, Hans Briem, Gerhard Siemeister, Ursula Mönning, Jozsef Balint
  • Patent number: 10171193
    Abstract: Methods, devices, and systems relating to Serial Attached SCSI (SAS) storage interconnect technology are provided. An SAS serial connection is established between an SAS initiator and an SAS expander over a physical link for communications between the SAS initiator and a plurality of target devices. The plurality of target devices is in communication with the SAS expander. SAS packets associated with each of the plurality of target devices are dynamically multiplexed and transmitted over the single SAS serial connection. Each SAS packet comprises one or more information bits indicating the target device with which the SAS packet is associated. The dynamically multiplexed SAS packets transmitted over the SAS connection may comprise SAS packets associated with at least two target devices having different maximum physical link rates. A result may be improved bandwidth utilization of the physical link when legacy SAS target devices with slower physical link rates are utilized.
    Type: Grant
    Filed: January 27, 2017
    Date of Patent: January 1, 2019
    Assignee: Microsemi Solutions (U.S.), Inc.
    Inventors: Gregory Arthur Tabor, John Matthew Adams, Keith Graham Shaw, Larrie Simon Carr, Salman Ghufran
  • Publication number: 20180222881
    Abstract: Compounds of formula (I) as described herein, processes for their production and their use as pharmaceuticals.
    Type: Application
    Filed: August 1, 2016
    Publication date: August 9, 2018
    Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Keith GRAHAM, Ulrich KLAR, Hans BRIEM, Gerhard SIEMEISTER, Ursula M?NNING
  • Publication number: 20180219641
    Abstract: Methods, devices, and systems relating to Serial Attached SCSI (SAS) storage interconnect technology are provided. An SAS serial connection is established between an SAS initiator and an SAS expander over a physical link for communications between the SAS initiator and a plurality of target devices. The plurality of target devices is in communication with the SAS expander. SAS packets associated with each of the plurality of target devices are dynamically multiplexed and transmitted over the single SAS serial connection. Each SAS packet comprises one or more information bits indicating the target device with which the SAS packet is associated. The dynamically multiplexed SAS packets transmitted over the SAS connection may comprise SAS packets associated with at least two target devices having different maximum physical link rates. A result may be improved bandwidth utilization of the physical link when legacy SAS target devices with slower physical link rates are utilized.
    Type: Application
    Filed: January 27, 2017
    Publication date: August 2, 2018
    Inventors: Gregory Arthur TABOR, John Matthew ADAMS, Keith Graham SHAW, Larrie Simon CARR, Salman GHUFRAN
  • Publication number: 20180162877
    Abstract: The present invention relates to substituted pyrazolopyridinamine compounds of general formula (I) as described and defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyperproliferative and/or angiogenesis disorder, inflammatory disease and disease associated with inflammatory pain, as a sole agent or in combination with other active ingredients.
    Type: Application
    Filed: December 14, 2015
    Publication date: June 14, 2018
    Inventors: Anja GIESE, Ulrich KLAR, Keith GRAHAM, Georg KETTSCHAU, Detlev SÜLZLE, Philip LIENAU, Kirstin PETERSEN, Julien LEFRANC, Nicole SCHMIDT
  • Publication number: 20180155285
    Abstract: Compounds of formula (I) as described hereinprocesses for their production and their use as anti-cancer agents.
    Type: Application
    Filed: June 14, 2016
    Publication date: June 7, 2018
    Applicant: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Keith GRAHAM, Ulrich KLAR, Hans BRIEM, Gerhard SIEMEISTER, Ursula MÕNNING, Jozsef BALINT
  • Publication number: 20180016272
    Abstract: Compound of formula (I), processes for their production and their use as pharmaceuticals.
    Type: Application
    Filed: January 25, 2016
    Publication date: January 18, 2018
    Applicant: Bayer Pharma Aktiengesellschaft
    Inventors: Keith GRAHAM, Ulrich KLAR, Hans BRIEM, Volker SCHULZE, Gerhard SIEMEISTER, Philip LIENAU, René TEMPEL, Jozsef BÁLINT
  • Patent number: 9724288
    Abstract: The present invention relates to aqueous personal care, household care, and/or fabric care compositions comprising the instant copolymers. Also disclosed are methods for the rheological modification of aqueous personal care, household care, and/or fabric care compositions comprising the instant copolymers.
    Type: Grant
    Filed: August 1, 2016
    Date of Patent: August 8, 2017
    Assignee: BASF SE
    Inventors: Keith Graham, David Normington, Howard Roger Dungworth, John Mark Plonka
  • Publication number: 20170172198
    Abstract: A crumb is manufactured by a process including adding an aqueous flour mixture into an extruder, partially extruding the aqueous mixture through the extruder, adding an aqueous gelling agent to the extruder at a point downstream of the start of the extrusion of the aqueous mixture through the extruder to form a resultant mixture of the aqueous mixture and the aqueous gelling agent in the extruder, and extruding the resultant mixture at a temperature greater than 100° C. to form an extrudate. The extrudate is allowed to expand, dried and milled to form the crumb, which has moisture-resistant properties particularly well-suited for use on frozen, microwavable food products.
    Type: Application
    Filed: March 6, 2017
    Publication date: June 22, 2017
    Inventor: Keith GRAHAM PICKFORD
  • Patent number: 9675612
    Abstract: The present invention relates to substituted thiazolopyrimidine compounds of general formula I as described and defined herein, to methods of preparing said compounds, to intermediate compounds useful for preparing said compounds, to pharmaceutical compositions and combinations comprising said compounds and to the use of said compounds for manufacturing a pharmaceutical composition for the treatment or prophylaxis of a disease, in particular of a hyperproliferative and/or angiogenesis disorder, as a sole agent or in combination with other active ingredients.
    Type: Grant
    Filed: March 3, 2014
    Date of Patent: June 13, 2017
    Assignee: BAYER PHARMA AKTIENGESELLSCHAFT
    Inventors: Ulrich Klar, Lars Wortmann, Keith Graham, Florian Puehler, Detlev Sülzle, Georg Kettschau, Philip Lienau