Abstract: The present disclosure relates to fluoride ion batteries and structures of metal based electrode materials for various fluoride ion batteries. The structures of the metal based electrode materials comprise one or more shells or interfaces, enabling the electrodes to operate at room temperature with a liquid electrolyte.

Abstract: A plurality of on-line and app-based systems and methods for purchasing new construction are provided, including, though not limited to, systems and methods for the integrated purchasing of new homes and related requirements such as home sites, elevations, interior designs, purchase contracts, and earnest money deposits.

Abstract: The present invention relates to compounds of formula I wherein A1, A2 R4 and Q are as defined herein. The compounds of the present invention are inhibitors of heat shock factor 1 (HSF1). In particular, the present invention relates to the use of these compounds as therapeutic agents for the treatment and/or prevention of proliferative diseases, such as cancer. The present invention also relates to processes for the preparation of these compounds, and to pharmaceutical compositions comprising them.

Abstract: A sealable connection system is provided. The system can include a connection assembly including a housing and at least one ferrule positioned within the housing. An inner surface of the housing can be arranged to mate with and secure to an outer surface of a sensor assembly. The at least one ferrule can be arranged to engage with the sensor assembly as the housing is secured to the sensor assembly. The system can also include a fiber optic cable assembly. The fiber optic cable assembly can include a fiber optic cable extending through the housing and the at least one ferrule. The fiber optic cable can also be surrounded, at least along a length of the fiber optic cable within the connection assembly, by a fiber optic cable cover. The sealable connection system is provided to hermetically connect the fiber optic cable assembly to a sensor assembly.

Abstract: A sealable connection system is provided. The system can include a connection assembly including a housing and at least one ferrule positioned within the housing. An inner surface of the housing can be arranged to mate with and secure to an outer surface of a sensor assembly. The at least one ferrule can be arranged to engage with the sensor assembly as the housing is secured to the sensor assembly. The system can also include a fiber optic cable assembly. The fiber optic cable assembly can include a fiber optic cable extending through the housing and the at least one ferrule. The fiber optic cable can also be surrounded, at least along a length of the fiber optic cable within the connection assembly, by a fiber optic cable cover. The sealable connection system is provided to hermetically connect the fiber optic cable assembly to a sensor assembly.

Abstract: The invention provides methods and compositions to enhance the efficiency and sensitivity of molecular inversion probe (MIP) reactions. Probes include elements that allow MIP ends to abut for ligation while avoiding the possibility of polymerase strand displacement errors. Elements facilitate multiplexed detections, including MIP reaction product detections employing next generation sequencing (NGS) techniques.

Abstract: An Automated Dynamic low voltage monitoring (LVM) based Low-Power (ADLLP) debug capability for a system-on-chip (SoC) as well as the open/closed-chassis platform for faster TTM (Time to Market) of the final platform or system. ADLLP Debug is achieved by detection of the probe connection between a target system (e.g., SoC) and debug host system. A user can dynamically override the power, clocks and LVM for intellectual property (IP) blocks not part of the debug trace by instructing a Power Management Controller (PMC) via the Inter Processor Communication (IPC) mailbox (or any other suitable mailbox driver) to set the registers in a Target Firmware (TFW) based on the probe and debug use-case.

Abstract: The present invention relates to N-(5-(2,3-dihydrobenzo[b][1,4]dioxine-6-carboxamido)-2-fluorophenyl)-2-((4-ethylpiperazin-1-yl)methyl)quinoline-6-carboxamide, or a pharmaceutically acceptable salt or solvate thereof, wherein at least one hydrogen atom has been substituted with a deuterium atom. Other aspects include pharmaceutical compositions comprising said compounds and medical uses and methods of treatment using said compounds.

Abstract: Methods and apparatus are provided for diagnosing a vehicle. In one embodiment, a method includes: initiating, by a processor, a recording of a noise by at least one microphone based on user selection data from a user of the vehicle; receiving, by the processor, audio signal data based on the recording; generating, by the processor, vector data based on the audio signal data; processing, by the processor, the vector data with at least one trained machine, by the processor, learning model to determine a classification of the noise; predicting, by the processor, an action to be taken based on the classification; and storing, by the processor, the audio signal data, the classification, and the action in a datastore.

Abstract: The present invention relates to compounds of formula I wherein A1, A2 R4 and Q are as defined herein. The compounds of the present invention are inhibitors of heat shock factor 1 (HSF1). In particular, the present invention relates to the use of these compounds as therapeutic agents for the treatment and/or prevention of proliferative diseases, such as cancer. The present invention also relates to processes for the preparation of these compounds, and to pharmaceutical compositions comprising them.

Abstract: Methods and apparatus are provided for diagnosing a vehicle. In one embodiment, a method includes: initiating, by a processor, a recording of a noise by at least one microphone based on user selection data from a user of the vehicle; receiving, by the processor, audio signal data based on the recording; generating, by the processor, vector data based on the audio signal data; processing, by the processor, the vector data with at least one trained machine, by the processor, learning model to determine a classification of the noise; predicting, by the processor, an action to be taken based on the classification; and storing, by the processor, the audio signal data, the classification, and the action in a datastore.

Abstract: A debug test system is provided. The debug test system includes one or more interfaces configured to communicate with a target system and processing circuitry configured to control the one or more interfaces. Further, the processing circuitry is configured to receive information about an operation state of the target system from the target system and to generate control information for the target system to adjust a debug session on the target system. The processing circuitry is further configured to transmit the control information to the target system.

Abstract: The present invention relates to compounds of formula I wherein A1, A2 R4 and Q are as defined herein. The compounds of the present invention are inhibitors of heat shock factor 1 (HSF1). In particular, the present invention relates to the use of these compounds as therapeutic agents for the treatment and/or prevention of proliferative diseases, such as cancer. The present invention also relates to processes for the preparation of these compounds, and to pharmaceutical compositions comprising them.

Abstract: A seal assembly includes a tensionable annular member and a gap seal annular member that are axially juxtaposed and configured to be carried by one of a pair of coaxially movable components for sealingly engaging another one of the pair of components. The tensionable annular member includes first and second radial surfaces, an inner surface, and an outer contact surface. Rounded bottom grooves are formed across the first radial surface from the outer contact surface to the inner surface. In another embodiment, notches are formed across the inner surface from the first radial surface to the second radial surface.

Abstract: An Automated Dynamic low voltage monitoring (LVM) based Low-Power (ADLLP) debug capability for a system-on-chip (SoC) as well as the open/closed-chassis platform for faster TTM (Time to Market) of the final platform or system. ADLLP Debug is achieved by detection of the probe connection between a target system (e.g., SoC) and debug host system. A user can dynamically override the power, clocks and LVM for intellectual property (IP) blocks not part of the debug trace by instructing a Power Management Controller (PMC) via the Inter Processor Communication (IPC) mailbox (or any other suitable mailbox driver) to set the registers in a Target Firmware (TFW) based on the probe and debug use-case.

Abstract: A Joint Test Access Group (JTAG) device can include a Joint Test Access Group (JTAG) port, transport layer circuitry to provide a communication to and from a debug device, and packet interpreter circuitry communicatively coupled between the JTAG port and the transport layer circuitry, the packet interpreter circuitry to translate data in a packet from the debug device into a sequence of bits to be provided to the JTAG port.

Abstract: The present invention relates to compounds of formula I as defined herein. The compounds of the present invention are inhibitors of heat shock factor 1 (HSF1). In particular, the present invention relates to the use of these compounds as therapeutic agents for the treatment and/or prevention of proliferative diseases, such as cancer. The present invention also relates to processes for the preparation of these compounds, and to pharmaceutical compositions comprising them.

Abstract: Methods, systems, and devices for providing matching security between data stores are described. In a database system, an operational data store may store transactional datasets and an analytical data store may store analytics datasets generated based on the transactional datasets. For these analytics datasets to efficiently inherit the security configurations of the transactional datasets, security information may be embedded in datasets retrieved from the operational data store during a data acquisition procedure. This security information may be converted into an embedded multiple-value field for storage in the analytical data store. The analytical data store may receive a query for data in a dataset, and may determine security descriptors associated with the user sending the query. The analytical data store may then filter the data based on comparing these determined security descriptors with the security information in the multiple-value field, and may transmit a query response with the filtered data.

Abstract: Systems and methods for automated aggregated content commenting are disclosed herein. Such a system can include a memory including a content database; an evaluation criteria database; and a comment database. The system can include at least one server. The at least one server can: receive a content identifier; receive a user identifier; provide a representation of the piece of content to the user; receive a comment from the user identifying a portion of the piece of content; generate a portion of the comment database linked to the user and the content; generate an entry in the portion of the comment database linked to the user and the content; and store the comment in the entry in the portion of the comment database.

Abstract: Methods, systems, and devices for providing matching security between data stores are described. In a database system, an operational data store may store transactional datasets and an analytical data store may store analytics datasets generated based on the transactional datasets. For these analytics datasets to efficiently inherit the security configurations of the transactional datasets, security information may be embedded in datasets retrieved from the operational data store during a data acquisition procedure. This security information may be converted into an embedded multiple-value field for storage in the analytical data store. The analytical data store may receive a query for data in a dataset, and may determine security descriptors associated with the user sending the query. The analytical data store may then filter the data based on comparing these determined security descriptors with the security information in the multiple-value field, and may transmit a query response with the filtered data.