Abstract: Apparatuses and methods of an integrated capacitance model circuit are described. A capacitance model circuit is disposed on a common carrier substrate of an integrated circuit (IC) having a capacitance-sensing device. The capacitance model circuit is configured to model a capacitance of an external sense array. The capacitance model circuit is programmable.

Abstract: Frequency domain optical coherence tomography (FD-OCT) systems and methods are provided. Thereby, a first measurement and a second measurement is performed, wherein in the first measurement an object region is illuminated by measuring light having a spectrum with a first spectral width and in the second measurement the object region is illuminated with measuring light having a spectrum with a second spectral width, wherein the first spectral width is at least 10% greater than the second spectral width. Further, during the first measurement intensities of spectral ranges of light having interacted with the object and being superimposed with reference light are detected, wherein a width of these spectral ranges is greater than a corresponding width during the second measurement. Thus, switching an axial field of view of structural information of the object across a depth direction is enabled upon minimizing radiation damage at the object.

Abstract: What is disclosed is a modular visualization display panel. The modular visualization display panel includes a first module having at least one surface and a connection to electrical ground. The modular visualization display panel also includes a second module having at least one surface with a plurality of raised contact nodes arranged on the one surface of the second module such that when in contact with the one surface of the first module electrostatic discharge energy is directed over at least one of the raised contact nodes to the one surface of the first module.

Abstract: An active integrator for sensing capacitance of a touch sense array is disclosed. The active integrator is configured to receive from the touch sense array a response signal having a positive portion and a negative portion. The response signal is representative of a presence or an absence of a conductive object on the touch sense array. The active integrator is configured to continuously integrate the response signal.

Abstract: The invention relates to computational methods, systems and apparatus useful in the analysis of sets of biomolecules in an accessible body fluid or tissue sample from a patient, which biomolecules collectively or individually are candidates to serve as biomarkers, i.e., biomolecules which together or individually upon detection or change are indicative that the patient is in some biological state, such as a diseased state. The methods permit one to examine such potential biological markers to determine whether each one is indeed present as a consequence of the biological state, or as an artifact of the biomarker search protocol.

Abstract: Method and system for managing and evaluating life science data. Life Science data is placed in a knowledge base, that may be used for a variety of analysis tasks. Creating a knowledge base from the life science data involves generating two or more nodes indicative of life science data, assigning to one or more pairs of nodes a representation descriptor that corresponds to a relationship between the nodes, and assembling the nodes and the relationship descriptor into a database, such that at least one of the nodes is joined to another node by a representation descriptor. In some embodiments, the representation descriptor includes a case frame that describes the relationships between elements of life science data.

Abstract: A surgical microscopy system is provided wherein an optical coherence tomography facility is integrated into a microscopy system. A beam of measuring light formed by collimating optics of an OCT system is deflected by a beam scanner, traverses imaging optics, and is reflected by a reflector such that the beam of measuring light traverses an objective lens of microscopy optics and is directed to an object region of the microscopy optics. A position of the beam of measuring light being incident on the reflector is substantially independent on a direction into which the beam of measuring light is deflected by the beam scanner. When traveling through the beam scanner, the beam of measuring light is comprised of a bundle of substantially parallel light rays.

Abstract: Imaging systems are provided allowing examination of different object regions spaced apart in a depth direction by visual microscopy and by optical coherence tomography. An axial field of view and a lateral resolution is varied depending on which object region is examined by the imaging system. The proposed imaging systems are in particular applicable for thorough examination of the human eye.

Abstract: Frequency domain optical coherence tomography (FD-OCT) systems and methods are provided. Thereby, a first measurement and a second measurement is performed, wherein in the first measurement an object region is illuminated by measuring light having a spectrum with a first spectral width and in the second measurement the object region is illuminated with measuring light having a spectrum with a second spectral width, wherein the first spectral width is at least 10% greater than the second spectral width. Further, during the first measurement intensities of spectral ranges of light having interacted with the object and being superimposed with reference light are detected, wherein a width of these spectral ranges is greater than a corresponding width during the second measurement. Thus, switching an axial field of view of structural information of the object across a depth direction is enabled upon minimizing radiation damage at the object.

Abstract: A computer implemented distributed workflow system includes a central server containing a management module and a datastore for storing workflow modules each having identifiable allocatable tasks requiring user input to complete. The management module is configured to define the workflow and manage the creation and distribution of the identifiable allocated tasks to one or more remote users, each having an associated handheld device and a locally stored application executable on the handheld device. Processing by the remote user of the identifiable allocated task is in response to a task initiation communication from the central server, which communicates with the remote handheld devices over a communications network. A user interface on the handheld device which facilitates data entry when the user completes the allocated task.

Abstract: Method and system for managing and evaluating life science data. Life Science data is placed in a knowledge base, that may be used for a variety of analysis tasks. Creating a knowledge base from the life science data involves generating two or more nodes indicative of life science data, assigning to one or more pairs of nodes a representation descriptor that corresponds to a relationship between the nodes, and assembling the nodes and the relationship descriptor into a database, such that at least one of the nodes is joined to another node by a representation descriptor. In some embodiments, the representation descriptor includes a case frame that describes the relationships between elements of life science data.

Abstract: An apparatus for material handling that is connected to a prime mover and preferably located forward of the mover, includes a plurality of rotary brushes with each of the rotary brushes being independently suspended and having their axes substantially normal to a surface and rotating in the same direction. The rotary brushes, when moving along the surface, tend to cause any material on the surface to be moved from one brush to another brush until the material on the surface is delivered to one side of the apparatus.

Abstract: The invention provides compositions containing hemoglobin, particularly PEGylated hemoglobin. The PEGylated hemoglobin molecule is capable of transferring oxygen or carbon monoxide bound thereto to a tissue with which it is in proximity. Exemplary PEGylated hemoglobin formulations of the invention are virally inactivated. Various compositions of the invention include deoxygenated hemoglobin, which may be conjugated with one or more water-soluble polymer. PEGylated hemoglobin includes those species in which the iron atom of the hemoglobin molecule is not bound to oxygen or any other species, and hemoglobin molecules in which a species other than oxygen, e.g., carbon monoxide, is bound to the iron atom. The compositions of the invention are formulated as hypo-, iso- or hypertonic solutions of the PEGylated hemoglobin. The compositions are of use to treat and/or ameliorate disease, injury and insult by providing for the oxygenation of tissues and/organs.

Abstract: Video and audio signals are streamed to remote viewers that are connected to a communication network. A host server receives an originating video and audio signal that may arrive from a single source or from a plurality of independent sources. The host server provides any combination of the originating video and audio signals to viewers connected to a communication network. A viewer requests the host server provide a combination of video and audio signals from the host server. The host server transmits an instruction set to be executed by the viewer. The instruction set causes the viewer to transmit parameters to the host user, including parameters relating to the processing capabilities of the viewer. The host server then transmits multimedia data to the viewer according to the received parameters. A plurality of viewers may be simultaneously connected to the host server.

Abstract: Video and audio signals are streamed to remote viewers that are connected to a communication network. A host server receives an originating video and audio signal that may arrive from a single source or from a plurality of independent sources. The host server provides any combination of the originating video and audio signals to viewers connected to a communication network. A viewer requests the host server provide a combination of video and audio signals from the host server. The host server transmits an instruction set to be executed by the viewer. The instruction set causes the viewer to transmit parameters to the host user, including parameters relating to the processing capabilities of the viewer. The host server then transmits multimedia data to the viewer according to the received parameters. A plurality of viewers may be simultaneously connected to the host server.

Abstract: Expressed Sequence Tags (ESTs) isolated from the unicellular green algae, Chlorella vulgaris, are disclosed. The invention encompasses nucleic acid molecules that encode Chlorella protein homologs and fragments thereof. In addition, antibodies capable of binding the proteins are encompassed by the present invention. The disclosed ESTs have particular utility in isolating genes and promoters, identifying and mapping the genes involved in developmental and metabolic pathways, and determining gene function. The ESTs provide a unique molecular tool for the targeting and isolation of novel genes for plant protection and improvement. The invention also relates to methods of using the disclosed nucleic acid molecules, proteins, fragments of proteins, and antibodies, for example, for gene identification and analysis, and preparation of constructs.

Abstract: A surgical microscopy system is provided wherein an optical coherence tomography facility is integrated into a microscopy system. A beam of measuring light formed by collimating optics of an OCT system is deflected by a beam scanner, traverses imaging optics, and is reflected by a reflector such that the beam of measuring light traverses an objective lens of microscopy optics and is directed to an object region of the microscopy optics. A position of the beam of measuring light being incident on the reflector is substantially independent on a direction into which the beam of measuring light is deflected by the beam scanner. When traveling through the beam scanner, the beam of measuring light is comprised of a bundle of substantially parallel light rays.

Abstract: The present invention relates to computational methods, systems and apparatus useful in the identification of similarities and/or differences between a plurality of biological states, such as altered biological states in an animal (e.g., a mammal or human). Particularly, the invention relates to comparing two or more causal system models (“CSMs”) which each are indicative of a biological state, such as a disease state, a toxic state, or a drug- or therapy-induced state. The present invention also relates to generating a general CSM from a comparison of two or more other CSMs, and subsequently comparing one or more of the other CSMs to the general CSM. Either of these techniques, or a combination of the two techniques, can be used to identify unique and common features in each CSM.

Abstract: The invention relates to computational methods, systems and apparatus useful in the analysis of sets of biomolecules in an accessible body fluid or tissue sample from a patient, which biomolecules collectively or individually are candidates to serve as biomarkers, i.e., biomolecules which together or individually upon detection or change are indicative that the patient is in some biological state, such as a diseased state. The methods permit one to examine such potential biological markers to determine whether each one is indeed present as a consequence of the biological state, or as an artifact of the biomarker search protocol.

Abstract: A system which provides workflow management includes a central server which is configured to communicate with two or more handheld computing devices to effect a delivery of specific work tasks to users of the respective handheld devices. By maintaining an interface with the handheld devices it is possible to coordinate and control performance of specific tasks within the workflow environment. A related method is also described.