Patents by Inventor Keith S. Lowe
Keith S. Lowe has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20130254935Abstract: Methods and compositions for modulating plant development are provided. Nucleotide sequences and amino acid sequences encoding Ovule Development Protein 2 (ODP2) proteins are provided. The sequences can be used in a variety of methods including modulating development, developmental pathways, altering oil content in a plant, increasing transformation efficiencies, modulating stress tolerance, and modulating the regenerative capacity of a plant. Transformed plants, plant cells, tissues, and seed are also provided.Type: ApplicationFiled: March 8, 2013Publication date: September 26, 2013Applicant: PIONEER HI-BRED INTERNATIONAL, INC.Inventors: William J. Gordon-Kamm, Timothy G. Helentjaris, Keith S. Lowe, Bo Shen, Mitchell C. Tarczynski (Deceased), Peizhong Zheng
-
Patent number: 8420893Abstract: Methods and compositions for modulating plant development are provided. Nucleotide sequences and amino acid sequences encoding Ovule Development Protein 2 (ODP2) proteins are provided. The sequences can be used in a variety of methods including modulating development, developmental pathways, altering oil content in a plant, increasing transformation efficiencies, modulating stress tolerance, and modulating the regenerative capacity of a plant. Transformed plants, plant cells, tissues, and seed are also provided.Type: GrantFiled: July 15, 2009Date of Patent: April 16, 2013Assignee: Pioneer Hi-Bred International, Inc.Inventors: William J. Gordon-Kamm, Timothy G. Helentjaris, Keith S. Lowe, Bo Shen, Mitchell C. Tarczynski, Peizhong Zheng
-
Patent number: 8383891Abstract: This invention relates to isolated polynucleotides encoding WUS polypeptides. The invention further provides isolated WUS polypeptides. The invention also provides methods of using the polynucleotides to modulate the level of WUS, improve transformation efficiency, to stimulate plant cell growth, including stem cells, to stimulate organogenesis, to stimulate somatic embryogenesis, to induce apomixis, and to provide a positive selection for cells comprising the polynucleotide. The invention also relates to cells, plants and seeds comprising the polynucleotides of the invention or produced by the methods of the invention.Type: GrantFiled: June 24, 2011Date of Patent: February 26, 2013Assignees: E.I. du Pont de Nemours and Company, Pioneer Hi-Bred International, Inc.Inventors: Rebecca E. Cahoon, William James Gordon-Kamm, Keith S. Lowe, Christopher Jay Scelonge, Yumin Tao
-
Patent number: 8080647Abstract: Compositions and methods relating to the use of tetracycline repressor in plants are provided. Compositions include a polynucleotide modified for expression in a plant, wherein the polynucleotide encodes a tetracycline repressor protein, as well as constructs, vectors, cells, plants and seeds comprising the polynucleotide, an/or produced by the methods. Also provided are methods to provide tetracycline repressor to a cell, and to regulate expression of a polynucleotide of interest in a cell, including a plant cell.Type: GrantFiled: November 15, 2007Date of Patent: December 20, 2011Assignee: Pioneer Hi Bred International IncInventors: William J. Gordon-Kamm, Keith S. Lowe, Christopher J. Scelonge, Carl R. Simmons, Aurélie Morin, Lawrence R. Stiner
-
Publication number: 20110287936Abstract: Compositions and methods relating to the use of sulfonylurea-mediated control of gene expression are provided. Compositions include sulfonylurea responsive chemical switches wherein the gene expression is regulated by a sulfonylurea compound. Compositions also include polynucleotides encoding the polypeptides as well as constructs, vectors, prokaryotic and eukaryotic cells, and eukaryotic organisms including plants and seeds comprising the polynucleotide, and/or produced by the methods. Also provided are methods to regulate expression of a polynucleotide of interest in a cell or organism, and methods to modify a genome, including in a plant or plant cell.Type: ApplicationFiled: April 14, 2011Publication date: November 24, 2011Applicants: E.I. duPont de Nemours and Company, Pioneer Hi-Bred International, Inc.Inventors: Jin Fang, William J. Gordon-Kamm, Keith S. Lowe, Kevin E. McBride, Brian McGonigle, Carl R. Simmons
-
Publication number: 20110258741Abstract: This invention relates to isolated polynucleotides encoding WUS polypeptides. The invention further provides isolated WUS polypeptides. The invention also provides methods of using the polynucleotides to modulate the level of WUS, improve transformation efficiency, to stimulate plant cell growth, including stem cells, to stimulate organogenesis, to stimulate somatic embryogenesis, to induce apomixis, and to provide a positive selection for cells comprising the polynucleotide. The invention also relates to cells, plants and seeds comprising the polynucleotides of the invention or produced by the methods of the invention.Type: ApplicationFiled: June 24, 2011Publication date: October 20, 2011Applicants: PIONEER HI-BRED INTERNATIONAL INC., E. I. DU PONT DE NEMOURS AND COMPANYInventors: Rebecca E. Cahoon, Keith S. Lowe, William J. Gordon-Kamm, Yumin Tao, Christopher J. Scelonge
-
Patent number: 7994391Abstract: This invention relates to isolated polynucleotides encoding WUS polypeptides. The invention further provides isolated WUS polypeptides. The invention also provides methods of using the polynucleotides to modulate the level of WUS, improve transformation efficiency, to stimulate plant cell growth, including stem cells, to stimulate organogenesis, to stimulate somatic embryogenesis, to induce apomixis, and to provide a positive selection for cells comprising the polynucleotide. The invention also relates to cells, plants and seeds comprising the polynucleotides of the invention or produced by the methods of the invention.Type: GrantFiled: January 23, 2008Date of Patent: August 9, 2011Assignees: E. I. du Pont de Nemours and Company, Pioneer Hi-Bred International, Inc.Inventors: Rebecca E. Cahoon, William James Gordon-Kamm, Yumin Tao, Keith S. Lowe, Christopher Jay Scelonge
-
Publication number: 20110167516Abstract: Compositions and methods are provided for the introduction and the regulated expression of genes in plants. Compositions include promoter constructs that provide a level of activity useful for the regulated expression of site-specific recombinases, while avoiding premature excision. Further provided are isolated polynucleotides encoding novel babyboom polypeptides, expression cassettes, and plants comprising the same. Methods for the introduction of genes into plants are provided, including methods for plastid transformation and methods for the transformation of tissues from mature seeds and leaves.Type: ApplicationFiled: December 30, 2010Publication date: July 7, 2011Applicant: Pioneer Hi-Bred International, Inc.Inventors: William J. Gordon-Kamm, Theodore M. Klein, Keith S. Lowe, Kevin E. McBride, Christopher J. Scelonge, Bing-Bing Wang, Ning Wang, Xinli E. Wu
-
Publication number: 20110167522Abstract: The invention provides isolated polynucleotides, specifically Cyclin D polynucleotides, and their encoded proteins that are involved in cell cycle regulation. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions. The present invention provides methods and compositions relating to altering cell cycle protein content and/or composition of plants for the purpose of increasing transformation efficiency.Type: ApplicationFiled: July 28, 2010Publication date: July 7, 2011Applicant: Pioneer Hi-Bred International, Inc.Inventors: Keith S. Lowe, Yumin Tao, William J. Gordon-Kamm, Carolyn A. Gregory, John A. McElver, George J. Hoerster, Sheila E. Maddock
-
Publication number: 20110165679Abstract: A variety of methods and compostions are provided, including methods and compositions for targeted modification of a specific target site in a cell or organism, methods for integrating polynucleotides of interest, methods to assess promoter activity, directly select transformed organisms, minimize or eliminate expression resulting from random integration into the genome of an organism, such as a plant, remove polynucleotides of interest, combine multiple transfer cassettes, invert or excise a polynucleotide, silence a gene, and identify and/or characterize transcriptional regulating regions. The methods involve the introduction of a cell proliferation factor and a double-strand break-inducing enzyme into an organism.Type: ApplicationFiled: December 30, 2010Publication date: July 7, 2011Applicant: Pioneer Hi-Bred International, Inc.Inventors: William J. Gordon-Kamm, Keith S. Lowe, David J. Peterson, Christopher J. Scelonge, Grace M. St. Clair, Bing-Bing Wang
-
Patent number: 7897383Abstract: Recombinant constructs useful for reducing the expression of endogenous mRNA and any substantially similar endogenous mRNA are disclosed. In particular, a recombinant construct comprising, inter alia, a suitable nucleic acid sequence and its reverse complement can be used to alter the expression of any homologous, endogenous RNA (i.e., the target RNA) which is in proximity to this suitable nucleic acid sequence.Type: GrantFiled: October 23, 2008Date of Patent: March 1, 2011Assignees: E. I. du Pont de Nemours and Company, Pioneer Hi-Bred InternationalInventors: Anthony J. Kinney, Kimberly F. Glassman, William James Gordon-Kamm, Keith S. Lowe, Scott E. Nichols, Kevin L. Stecca
-
Publication number: 20110010795Abstract: Methods and compositions for modulating plant development are provided. Nucleotide sequences and amino acid sequences encoding Ovule Development Protein 2 (ODP2) proteins are provided. The sequences can be used in a variety of methods including modulating development, developmental pathways, altering oil content in a plant, increasing transformation efficiencies, modulating stress tolerance, and modulating the regenerative capacity of a plant. Transformed plants, plant cells, tissues, and seed are also provided.Type: ApplicationFiled: July 15, 2009Publication date: January 13, 2011Applicant: Pioneer Hi-Bred International, Inc.Inventors: William J. Gordon-Kamm, Timothy G. Helentjaris, Keith S. Lowe, Bo Shen, Mitchell C. Tarczynski, Peizhong Zheng
-
Publication number: 20100285591Abstract: The invention provides isolated polynucleotides, specifically Cyclin D polynucleotides, and their encoded proteins that are involved in cell cycle regulation. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions. The present invention provides methods and compositions relating to altering cell cycle protein content and/or composition of plants for the purpose of increasing transformation efficiency.Type: ApplicationFiled: July 27, 2010Publication date: November 11, 2010Applicant: Pioneer Hi-Bred International, Inc.Inventors: Keith S. Lowe, Yumin Tao, William J. Gordon-Kamm, Carolyn A. Gregory, John A. McElver, George J. Hoerster, Sheila E. Maddock
-
Patent number: 7799566Abstract: The invention provides isolated polynucleotides, specifically Cyclin D polynucleotides, and their encoded proteins that are involved in cell cycle regulation. The invention further provides recombinant expression cassettes, host cells, transgenic plants, and antibody compositions. The present invention provides methods and compositions relating to altering cell cycle protein content and/or composition of plants for the purpose of increasing transformation efficiency.Type: GrantFiled: November 16, 2006Date of Patent: September 21, 2010Assignee: Pioneer Hi-Bred International, Inc.Inventors: Keith S. Lowe, Yumin Tao, William J. Gordon-Kamm, Carolyn A. Gregory, John A. McElver, George J. Hoerster, Sheila E. Maddock
-
Publication number: 20100100981Abstract: This invention relates to isolated polynucleotides encoding WUS polypeptides. The invention further provides isolated WUS polypeptides. The invention also provides methods of using the polynucleotides to modulate the level of WUS, improve transformation efficiency, to stimulate plant cell growth, including stem cells, to stimulate organogenesis, to stimulate somatic embryogenesis, to induce apomixis, and to provide a positive selection for cells comprising the polynucleotide. The invention also relates to cells, plants and seeds comprising the polynucleotides of the invention or produced by the methods of the invention.Type: ApplicationFiled: January 23, 2008Publication date: April 22, 2010Applicants: PIONEER HI-BRED INTERNATIONAL INC., E.I. DUPONT DE NEMOURS & COMPANYInventors: Rebecca E. Cahoon, Keith S. Lowe, William J. Gordon-Kamm, Yumin Tao, Christopher J. Scelonge
-
Publication number: 20090328252Abstract: Methods and compositions for modulating plant development are provided. Nucleotide sequences and amino acid sequences encoding Ovule Development Protein 2 (ODP2) proteins are provided. The sequences can be used in a variety of methods including modulating development, developmental pathways, altering oil content in a plant, increasing transformation efficiencies, modulating stress tolerance, and modulating the regenerative capacity of a plant. Transformed plants, plant cells, tissues, and seed are also provided.Type: ApplicationFiled: July 15, 2009Publication date: December 31, 2009Applicant: Pioneer Hi-Bred International, Inc.Inventors: William J. Gordon-Kamm, Timothy G. Helentjaris, Keith S. Lowe, Bo Shen, Mitchell C. Tarczynski, Peizhong Zheng
-
Patent number: 7579529Abstract: Methods and compositions for modulating plant development are provided. Nucleotide sequences and amino acid sequences encoding Ovule Development Protein 2 (ODP2) proteins are provided. The sequences can be used in a variety of methods including modulating development, developmental pathways, altering oil content in a plant, increasing transformation efficiencies, modulating stress tolerance, and modulating the regenerative capacity of a plant. Transformed plants, plant cells, tissues, and seed are also provided.Type: GrantFiled: January 28, 2005Date of Patent: August 25, 2009Assignee: Pioneer Hi-Bred International, Inc.Inventors: William J. Gordon-Kamm, Timothy G. Helentjaris, Keith S. Lowe, Bo Shen, Mitchell C. Tarczynski, Peizhong Zheng
-
Patent number: 7569746Abstract: The invention relates to the use of a modified Agrobacterium to deliver proteins directly to plant cells. Proteins of interest are delivered to the plant host in the form of a fusion protein with the Agrobacterium virulence protein VirF. Nucleotide sequences encoding such fusion proteins of VirF and a protein of interest are provided. Also provided are bacteria modified to comprise such fusion proteins of VirF and a protein of interest. Methods of introducing such fusion proteins into a plant host are provided. The invention finds use in facilitating plant transformation and particularly in the bio-engineering of desirable traits into crop plants.Type: GrantFiled: August 6, 2004Date of Patent: August 4, 2009Assignees: Pioneer Hi-Bred International, Inc., Purdue Research FoundationInventors: Matthew A. Bailey, Stanton B. Gelvin, Saikat Bhattacharjee, William J. Gordon-Kamm, Keith S. Lowe, Yumin Tao
-
Publication number: 20090142829Abstract: Recombinant constructs useful for reducing the expression of endogenous mRNA and any substantially similar endogenous mRNA are disclosed. In particular, a recombinant construct comprising, inter alia, a suitable nucleic acid sequence and its reverse complement can be used to alter the expression of any homologous, endogenous RNA (i.e., the target RNA) which is in proximity to this suitable nucleic acid sequence.Type: ApplicationFiled: October 23, 2008Publication date: June 4, 2009Inventors: Kimberly F. Glassman, William J. Gordon-Kamm, Anthony J. Kinney, Keith S. Lowe, Scott E. Nichols, Kevin L. Stecca
-
Patent number: 7432418Abstract: The present invention provides compositions and methods for regulating expression of isolated nucleotide sequences in a plant. The compositions are novel nucleic acid sequences for callus-tissue and seed embryo-preferred regulatory sequences. Methods for expressing an isolated nucleotide sequence in a plant or callus tissue using the regulatory sequences are also provided. The methods comprise transforming a plant cell to contain an isolated nucleotide sequence operably linked to the regulatory sequences of the present invention and regenerating a stably transformed plant or callus tissue from the transformed plant cell.Type: GrantFiled: September 11, 2006Date of Patent: October 7, 2008Assignee: Pioneer Hi-Bred International, Inc.Inventors: Shane E. Abbitt, William J. Gordon-Kamm, Keith S. Lowe