Abstract: Humanized, chimeric and human anti-CD20 antibodies and CD20 antibody fusion proteins that bind to a human B cell marker, referred to as CD20, which are useful for the treatment and diagnosis of B-cell disorders, such as B-cell malignancies and autoimmune diseases, and methods of treatment and diagnosis are disclosed. Methods of making the humanized, chimeric and human anti-CD20 antibodies are disclosed. A humanized anti-HSG (histamine-succinyl-glycyl) monoclonal antibody designated h679 which binds with high affinity to molecules containing the moiety histamine-succinyl-glycyl (HSG), and methods of making the humanized anti-HSG antibody also are disclosed.

Abstract: An isoxazole derivative is provided. The isoxazole derivative has following formula: wherein R1, R2, R3, R4 and R5, independently, include hydrogen, hydroxy or C1-C12 alkoxy optionally substituted with oxirane, thiirane, aziridine, amino, cycloamino, aminohydroxy or cycloaminohydroxy. The invention also provides a pharmaceutical composition for treatment of osteoporosis and cancer including an isoxazole derivative or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable carrier.

Abstract: An isoflavone derivative is provided. The isoxazole derivative has following formula: wherein R1 and R2, independently, include C1-C12 alkyl optionally substituted with oxirane, thiirane, aziridine, amino, cycloamino, aminohydroxy or cycloaminohydroxy, and R3 includes hydrogen, hydroxy or C1-C12 alkoxy optionally substituted with oxirane, thiirane, aziridine, amino, cycloamino, aminohydroxy or cycloaminohydroxy. The invention also provides a pharmaceutical composition for treatment of osteoporosis including an isoflavone derivative or a pharmaceutically acceptable salt thereof and a pharmaceutically acceptable carrier.

Abstract: Stem cell transfection method. The stem cell infection method of the invention comprises providing a stem cell; positioning the stem cell at a buffer, wherein the buffer contains a foreign material; electroporating the stem cell in the buffer; and culturing the stem cell.

Abstract: A medium for culturing stem cell. The stem cell medium of the invention comprises a fetal bovine serum, one or plurality of amino acid, one or plurality of vitamin, one or plurality of growth factor, one or plurality of inorganic salt, one or plurality of antioxidant, wherein the stem cell medium has a calcium concentration of less than about 1.8 mM, and the fetal bovine serum is present in an amount of less than about 10% by volume of the medium. The stem cell medium of the invention can maintain the proliferative and self-renewal capacity of the stem cells and keep stem cells at a steady stage.

Abstract: Toona sinensis extract for suppressing the proliferation and inducing apoptosis of osteosarcoma, but not normal human osterblasts. The extraction process comprises: extracting Toona sinensis with water to obtain a first extract, and filtering the first extract by a membrane to obtain a filtrate, and the Toona sinensis extract of the invention does not cause biological damages of normal bone cells. In addition, the invention further provides a pharmaceutical composition comprising the Toona sinensis extract.

Abstract: Recombinant immunotoxins containing a cytotoxic RNAse fused to an antibody or antibody fragment may be produced in mammalian cell culture. Surprisingly, immunotoxins containing a cytotoxic RNAse fused to the N-terminus of one antibody variable domain can be prepared and retain the ability to specifically bind antigen. The immunotoxins may be used in a variety of therapeutic methods for treating diseases or syndromes associated with unwanted or inappropriate cell proliferation or activation.

Abstract: Methods and compositions are described for targeting therapeutic and diagnostic molecules to particular types of cells using targeting antibodies or other targeting moeities.

Abstract: A method for displaying pictures during a digital picture slide show includes receiving a plurality of pictures, determining display characteristics of the plurality of pictures according to weighting values of the plurality of pictures, and displaying the plurality of pictures according to the display characteristics of the plurality of pictures.

Abstract: A controlled release system and manufacturing method thereof. The method comprises providing a first aqueous solution containing a hydrophilic drug and an alkaline agent, providing an organic solution containing a hydrophobic molecule, providing a second aqueous solution containing a hydrophilic surfactant, mixing the first hydrophilic solution with the organic solution to form a first emulsion, and mixing the first emulsion with a second aqueous solution to form a second emulsion containing delayed-release microsphere.

Abstract: A method and an apparatus of displaying component video signals. Firstly, a component video signal is received, and a vertical synchronous signal and a horizontal synchronous signal are separated from the component video signal. Thereafter, the format of the component video signal is determined by analyzing the vertical synchronous signal and the horizontal synchronous signal, and a video processing route corresponding to the format of the component video signal is chosen to generate visual output from the component video signal. Thus the visual output is displayed.

Abstract: Disclosed herein is a three-dimensional culture containing human articular chondrocytes with induced terminal differentiation changes, as well as a process for preparing the same. The three-dimensional culture, which was found to mimic the biological characteristics of articular chondrocytes that undergo terminal differentiation in vivo, can be used as a tool in the studies of the molecular and cellular mechanisms of osteoarthritis, and in the screening of candidate drugs for use in treatment of a disorder associated with articular chondrocytes.

Abstract: A projection display apparatus and method of preventing from inadvertently inputting command thereof are provided for preventing users from inadvertently inputting the command to shut down a discharge lamp of the projection display apparatus. The method comprises the following steps: preparing to enter a determination mode when a projection display apparatus receives a activation signal; displaying the predetermined delay time on a screen of the projection display apparatus and down counting such delay time; determining whether a confirmation signal is received during the delay time; and shutting down the discharge lamp when the project display apparatus receives the confirmation signal. If the projection display apparatus fails to receive the confirmation signal or receive other signals during the delay time, the projection display apparatus will return to the normal display mode.

Abstract: A display device includes a driving unit and a processing unit. If the driving unit operates abnormally during a power-on period, the processing unit generates a control signal according to a driving signal outputted by the driving unit. In response to the control signal, the driving unit is reset and then re-outputs the driving signal. A method for recovering from abnormal power-on therefor includes generating two signals, wherein one signal is adapted for re-activating a light source and the other is adapted for resetting the driving unit so that the driving unit may re-output the driving signal.

Abstract: A disk drive includes a storage disk, a data transducer, an actuator assembly and a positioner. The actuator assembly supports the data transducer over the storage disk. The actuator assembly includes a rotatable actuator hub and a longitudinal axis. The positioner moves the actuator assembly to position the data transducer relative to the storage disk. During movement of the actuator assembly, the actuator hub is subject to a resultant force that causes track misregistration of the data transducer. The positioner includes a magnet assembly that generates a magnetic field, a first conductor region and a second conductor region. In one embodiment, the conductor regions cooperate with the magnet assembly to generate a first force and a second force that are each directed at an angle having an absolute value that is greater than zero degrees and less than approximately 45 degrees relative to the longitudinal axis of the actuator assembly.

Abstract: A positioner (20) for a disk drive (10) that includes a magnet assembly (52), a conductor assembly (54), and a control system (22) is provided herein. The magnet assembly (52) includes a pair of magnet arrays (56A) (56B) and a pair of spaced apart flux return plates (75A) (75B). The conductor assembly (54) includes at least a first coil array (80) and a second coil array (82) that are substantially co-planar. The control system (22) directs current to electrically excite the coil arrays (80) (82) to maintain a data transducer (50) on a target track (32) of a storage disk (28).

Abstract: A composite radar absorption structure with a thin shell type and a method for manufacturing the same are provided. The composite radar absorption structure at lease comprising a continuous fibrous material and a plurality of filling mediums, wherein the plurality of filling mediums are uniformly distributed over the surface perpendicular to the thickness direction in the continuous fibrous material; and a volume percentage of the plurality of filling mediums are between 10 vol. % and 25 vol. % of the continuous fibrous material.

Abstract: Transmit parallel interfaces and methods are provided in which a clock signal is generated that maximizes the setup and hold window of input data. In at least some embodiments, a divider circuit provides a clock signal in one clock domain that has a rising edge located very close to the falling edge of a system clock in another clock domain.

Abstract: A positioner (20) for a disk drive (10) that includes a magnet assembly (52), a conductor assembly (54), and a control system (22) is provided herein. The magnet assembly (52) includes a pair of magnet arrays (56A) (56B) and a pair of spaced apart flux return plates (75A) (75B). The conductor assembly (54) includes a coil array (78). The coil array includes a first portion (84) and a second portion (86) that are positioned substantially perpendicular to a longitudinal axis (43) of an E-block (16). The control system (22) directs current to electrically excite the first and second portions (84) (86) to generate a first force F1 and a second force F2 which are (i) parallel to the longitudinal axis (43) of the E-block (16), and (ii) equal in magnitude and directionally opposite to better position a data transducer (50) on a target track (32) of a storage disk (28).

Abstract: A method for searching television channel is provided. An initial frequency and a frequency search interval are set. Thereafter, using the initial frequency as the starting point, television signals are scanned to find any television channel within a designated frequency bandwidth. The channel ID is resolved from the channel frequency based on a specific broadcasting system on each detecting of the channel signals. The channel frequency and frequency ID of any television channel thus found are also stored. In this invention, the television channel is searched by frequency instead of a channel table as in a conventional method.