Abstract: Embodiments of the present disclosure are directed toward systems including a turbomachine blade tip shroud having a pressure side portion and a suction side portion. The pressure side portion and the suction side portion are divided by a mean camber line of a turbomachine blade, and the pressure side portion has a greater surface area than the suction side portion.

Abstract: Turbine frequency tuning, fluid dynamic efficiency, and performance can be improved using an airfoil profile and/or an endwall contour including at least one of a pressure side bump, a pressure side leading edge bump, or a suction side trough. In particular, by including two endwall bumps on the pressure side and a trough on the suction side combined with a particular airfoil profile, performance can be further improved.

Abstract: Embodiments of the invention relate generally to turbomachines and, more particularly, to the positioning of airfoils to reduce pressure variations entering a diffuser. One embodiment includes a turbomachine comprising a diffuser, a plurality of airfoil rows, including a first airfoil row adjacent the diffuser, the first airfoil row being of a first type selected from a group consisting of stationary vanes and rotating blades, a second airfoil row adjacent the first airfoil row, the second airfoil row being of a second type different from the first type, and a third airfoil row of the first type adjacent the second airfoil row, wherein at least one of the plurality of airfoil rows is clocked, relative to another airfoil row of the turbomachine, reducing variations in airflow circumferential pressure at at least one spanwise location in the diffuser adjacent the first airfoil row in an operative state of the turbomachine.

Abstract: A turbine bucket is provided including a bucket airfoil having an airfoil shape, the bucket airfoil having a nominal profile substantially in accordance with Cartesian coordinate values of X, Y and Z set forth in Table 1 wherein the Z values are non-dimensional values from 0% to 100% convertible to Z distances in inches by multiplying the Z values by a height of the airfoil in inches and adding the radius of the airfoil base, and wherein X and Y are distances in inches which, when connected by smooth continuing arcs, define airfoil profile sections at each distance Z, the profile sections at the Z distances being joined smoothly with one another to form a complete airfoil shape.

Abstract: A turbine nozzle is provided including a nozzle airfoil having an airfoil shape, the nozzle airfoil having a nominal profile substantially in accordance with Cartesian coordinate values of X, Y and Z set forth in Table 1 wherein the Cartesian coordinate values of X, Y and Z are non-dimensional values from 0% to 100% convertible to dimensional distances in inches by multiplying the Cartesian coordinate values of X, Y and Z by a height of the airfoil in inches, and wherein X and Y are distances in inches which, when connected by smooth continuing arcs, define airfoil profile sections at each distance Z, the airfoil profile sections at Z distances being joined smoothly with one another to form a complete airfoil shape.

Abstract: The present invention provides a method of analysing a sample comprising sub-micron particles, comprising determining first information about the size of particles and number of particles in the sample by nanoparticle tracking analysis; determining second information about average particle size of particles in the sample by dynamic light scattering; determining from the first information third information representing the theoretical effect of the detected particles on results obtainable by dynamic light scattering; and adjusting the second information using the third information to produce fourth information representing adjusted information on average particle size.

Abstract: A turbine bucket is provided including a bucket airfoil having an airfoil shape, the bucket airfoil having a nominal profile substantially in accordance with Cartesian coordinate values of X, Y and Z set forth in Table 1 wherein the Cartesian coordinate values of X, Y and Z are non-dimensional values from 0% to 100% convertible to dimensional distances in inches by multiplying the Cartesian coordinate values of X, Y and Z by a height of the airfoil in inches, and wherein X and Y are distances in inches which, when connected by smooth continuing arcs, define airfoil profile sections at each distance Z, the airfoil profile sections at Z distances being joined smoothly with one another to form a complete airfoil shape.

Abstract: A method for enhancing one or more performance parameters of a gas turbine having at least one row of clocked airfoils may generally include choosing a first, a second and a third row of airfoils where the third row is clocked relative to the first row. An unsteady computational fluid dynamics model may be used to determine at least one wake parameter of a working fluid flowing from the second row of the airfoils to the third row of the airfoils. At least one design parameter of the airfoils of the second row may be modified, and the unsteady computational fluid dynamics model may then be used to determine the effect of the airfoil design parameter modification on the at least one wake parameter. The effect on the wake parameter may be compared to a predetermined target range.

Abstract: Embodiments of the present disclosure are directed toward systems including a turbomachine blade tip shroud having a pressure side portion and a suction side portion. The pressure side portion and the suction side portion are divided by a mean camber line of a turbomachine blade, and the pressure side portion has a greater surface area than the suction side portion.

Abstract: A turbine bucket is provided including a bucket airfoil having an airfoil shape, the bucket airfoil having a nominal profile substantially in accordance with Cartesian coordinate values of X, Y and Z set forth in Table 1 wherein the Cartesian coordinate values of X, Y and Z are non-dimensional values from 0% to 100% convertible to dimensional distances in inches by multiplying the Cartesian coordinate values of X, Y and Z by a height of the airfoil in inches, and wherein X and Y are distances in inches which, when connected by smooth continuing arcs, define airfoil profile sections at each distance Z, the airfoil profile sections at Z distances being joined smoothly with one another to form a complete airfoil shape.

Abstract: A turbine nozzle is provided including a nozzle airfoil having an airfoil shape, the nozzle airfoil having a nominal profile substantially in accordance with Cartesian coordinate values of X, Y and Z set forth in Table 1 wherein the Cartesian coordinate values of X, Y and Z are non-dimensional values from 0% to 100% convertible to dimensional distances in inches by multiplying the Cartesian coordinate values of X, Y and Z by a height of the airfoil in inches, and wherein X and Y are distances in inches which, when connected by smooth continuing arcs, define airfoil profile sections at each distance Z, the airfoil profile sections at Z distances being joined smoothly with one another to form a complete airfoil shape.

Abstract: A turbine of a turbomachine is provided and includes opposing endwalls defining a pathway for a fluid flow and a plurality of interleaved blade stages and nozzle stages arranged axially along the pathway. The plurality of the blade stages includes a last blade stage at a downstream end of the pathway and a next-to-last blade stage upstream from the last blade stage. The plurality of the nozzle stages includes a last nozzle stage between the last blade stage and the next-to-last blade stage and a next-to-last nozzle stage upstream from the next-to-last blade stage. At least one of the next-to-last blade stage and the next-to-last nozzle stage includes aerodynamic elements configured to interact with the fluid flow and to define a throat distribution producing a tip strong pressure profile in the fluid flow.

Abstract: A turbine bucket is provided including a bucket airfoil having an airfoil shape, the bucket airfoil having a nominal profile substantially in accordance with Cartesian coordinate values of X, Y and Z set forth in Table 1 wherein the Z values are non-dimensional values from 0% to 100% convertible to Z distances in inches by multiplying the Z values by a height of the airfoil in inches and adding the radius of the airfoil base, and wherein X and Y are distances in inches which, when connected by smooth continuing arcs, define airfoil profile sections at each distance Z, the profile sections at the Z distances being joined smoothly with one another to form a complete airfoil shape.

Abstract: Matrimony (Mtrm) acts as a negative regulator of Polo kinase (Polo) during the later stages of G2 arrest. Indeed, both the repression of Polo expression until stage 11 and the inactivation of newly synthesized Polo by Mtrm until stage 13 play critical roles in maintaining and properly terminating G2 arrest. Our data suggest a model in which the eventual activation of Cdc25 by an excess of Polo at stage 13 triggers NEB and entry into prometaphase. In view of the foregoing, methods for modulating oocyte maturation are provided. More particularly, methods are provided for in vitro maturation of an oocyte. Further provided are methods for identifying functional orthologs of a Drosophila Matrimony polypeptide, as well as inhibitors thereof.

Abstract: The present invention generally relates to the field of woodworking tools and particularly to an indexing assembly for a lathe. An aspect of the present invention is directed to a lathe, including a frame; a bed coupled with the frame; a head stock configured for mechanically engaging a first end of a workpiece, the head stock being coupled with the bed; and a tail stock, including a housing, the housing including a fine adjustment assembly for mechanically engaging with a second end of the workpiece, wherein the tail stock is adjustably and slidably coupled with the bed via an indexing assembly, the indexing assembly configured to provide the lathe with positive locking capabilities.

Abstract: The present invention generally relates to the field of woodworking tools and particularly to an indexing assembly for a lathe. An aspect of the present invention is directed to a lathe, including a frame; a bed coupled with the frame; a head stock configured for mechanically engaging a first end of a workpiece, the head stock being coupled with the bed; and a tail stock, including a housing, the housing including a fine adjustment assembly for mechanically engaging with a second end of the workpiece, wherein the tail stock is adjustably and slidably coupled with the bed via an indexing assembly, the indexing assembly configured to provide the lathe with positive locking capabilities.

Abstract: Low doses of IL-2 are administered to potentiate an immune response after antiviral treatment. IL-2 is also administered in conjunction with immunotherapy to enhance the immune response to infection.

Abstract: A method of activating the immune system of a subject comprises the chronic administration of low doses of an agent having cytokine activity, including natural and recombinant cytokines, fragments, analogues, fusion proteins, and derivatives thereof, that are pharmaceutically acceptable, and their mixtures with other biologically active agents and formulation ingredients. The agent is provided as a unit dosage form, in systemic and topical product form, as an implant, inhalant, transdermal delivery device, and ultrasound and electrotransport devices, as well as in the form of a kit for self-administration.

Abstract: Disclosed are an isolated antibody or antibody fragment that selectively binds a polypeptide encoded by Cytokine Response gene 2 (CR2), and in particular, selectively binds to a first polypeptide having the sequence of residues 1-60 of SEQ. ID No: 4. Also disclosed is a composition containing the antibody or antibody fragment and a diluent or carrier. Also disclosed are methods, using the present antibody or antibody fragment, of isolating or purifying a peptide comprising an amino acid sequence of residues 1-60 of SEQ. ID No: 4 or an antibody binding fragment thereof that is at least 10 to 30 amino acids long, or a fusion protein comprising any of these.

Abstract: In a virtual reality system (20) an operator perceives being in a virtual reality world (74) of virtual reality images (62). The system (20) models the relative position and movement of objects (208 and 210) in a virtual reality world (74) by representing graphically a first (208) and second (210) object in a virtual reality world (74) on a graphical display (60 and 68). The representation selective obscures the first (208) and second (210) objects according to the relative position of the objects (208 and 210) to a predetermined observation point in the virtual reality world (74). The system (20) then determines a first partitioning plane (204) between the first (208) and second (210) objects. Then, the system (20) method determines a second partition plane (206) between the first (208) and second (210) object in response to either of said first (208) or second (210) objects moving across the first partitioning plane (204).