Patents by Inventor Kenichi Mitsui
Kenichi Mitsui has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20200147233Abstract: It is an object of the present invention to provide a method for killing tumor cells, having a few side effects. The present invention provides a method for killing tumor cells, comprising: (1) a step of allowing an immunotoxin formed by binding an antibody binding to ROBO1 or a fragment thereof to a cytotoxin to come into contact with tumor cells; (2) a step of allowing a photosensitizer that induces photochemical cytoplasmic internalization to come into contact with the tumor cells; and (3) a step of irradiating the tumor cells with a wave length that is effective for activating the sensitizer, so as to kill the cells.Type: ApplicationFiled: October 3, 2019Publication date: May 14, 2020Applicant: PhotoQ3 Inc.Inventors: Takao HAMAKUBO, Noriko KOMATSU, Kenichi MITSUI, Osamu ARAI, Hiroko IWANARI, Tsuyoshi TAKATO, Takahiro ABE
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Patent number: 9644569Abstract: Provided is a boot seal for a variable compression ratio engine having an inner layer free from tears or creases. The boot seal comprises a boot body having a cylinder-attaching part, a crankcase-attaching part and a connecting part for connecting these parts, and a rigid plate disposed in at least one of the cylinder-attaching part and the crankcase-attaching part and having a through hole. The boot body comprises an outer layer formed by injection molding a rubber material, and an inner layer formed of fluorine-containing rubber. An injection gate for the outer layer is located at a portion of the outer layer opposing the rigid plate. Both an outer surface and an inner surface of at least a portion of the rigid plate having the through hole are covered with the rubber material supplied from the injection gate.Type: GrantFiled: January 7, 2015Date of Patent: May 9, 2017Assignees: TOYODA GOSEI CO., LTD., TOYOTA JIDOSHA KABUSHIKI KAISHAInventors: Kenichi Mitsui, Tadanobu Ota, Yoshiki Shimoda, Kaoru Ito
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Publication number: 20150192090Abstract: Provided is a boot seal for a variable compression ratio engine having an inner layer free from tears or creases. The boot seal comprises a boot body having a cylinder-attaching part, a crankcase-attaching part and a connecting part for connecting these parts, and a rigid plate disposed in at least one of the cylinder-attaching part and the crankcase-attaching part and having a through hole. The boot body comprises an outer layer formed by injection molding a rubber material, and an inner layer formed of fluorine-containing rubber. An injection gate for the outer layer is located at a portion of the outer layer opposing the rigid plate. Both an outer surface and an inner surface of at least a portion of the rigid plate having the through hole are covered with the rubber material supplied from the injection gate.Type: ApplicationFiled: January 7, 2015Publication date: July 9, 2015Inventors: Kenichi MITSUI, Tadanobu OTA, Yoshiki SHIMODA, Kaoru ITO
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Patent number: 8936248Abstract: A boot seal for variable compression-rate engine includes a boot-seal element, and a reinforcement member. The boot-seal element includes an inner layer, and an outer layer. The inner layer is disposed on the inner face of the boot-seal element, and is composed of a fluorinated rubber. The outer layer is disposed on a more outer side of the boot-seal element than is the inner layer. Moreover, the boot-seal element is formed in a circumferentially developed state so as to have circumferential ends, and is then completed by joining the circumferential ends with each other. Thus, the boot-seal element makes an elastically deformable cylindrical bellows shape having a root that dents inward diametrically. In addition, the reinforcement member is disposed in the root of the cylindrical bellows-shaped boot-seal element at least.Type: GrantFiled: February 29, 2012Date of Patent: January 20, 2015Assignees: Toyoda Gosei Co., Ltd., Toyota Jidosha Kabushiki KaishaInventors: Kenichi Mitsui, Katsuhisa Ota, Kaoru Itou
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Patent number: 8293397Abstract: A battery assembly includes single-battery cells, and thermally-conductive members. The thermally-conductive members are formed of a soft material as a plated configuration. The soft material exhibits thermal conductivity and electric insulatability. The single-battery cells, and the thermally-conductive members are adhered to each other, and are disposed one after another alternately in a row, thereby interposing the thermally-conducive members between the single-cell batteries. The thermally-conductive members include a radiation surface respectively from which heat that the single-battery cells produce radiates. The single-battery cells are cooled indirectly by cooling the radiation surfaces of the thermally-conductive members.Type: GrantFiled: July 31, 2008Date of Patent: October 23, 2012Assignee: Toyoda Gosei Co., Ltd.Inventors: Yasunori Uchida, Kimio Tsubaki, Shigeki Takeo, Hiroshi Onaka, Tatsuo Suzuki, Kenichi Mitsui
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Publication number: 20120248712Abstract: A boot seal for variable compression-rate engine includes a boot-seal element, and a reinforcement member. The boot-seal element includes an inner layer, and an outer layer. The inner layer is disposed on the inner face of the boot-seal element, and is composed of a fluorinated rubber. The outer layer is disposed on a more outer side of the boot-seal element than is the inner layer. Moreover, the boot-seal element is formed in a circumferentially developed state so as to have circumferential ends, and is then completed by joining the circumferential ends with each other. Thus, the boot-seal element makes an elastically deformable cylindrical bellows shape having a root that dents inward diametrically. In addition, the reinforcement member is disposed in the root of the cylindrical bellows-shaped boot-seal element at least.Type: ApplicationFiled: February 29, 2012Publication date: October 4, 2012Applicants: TOYOTA JIDOSHA KABUSHIKI KAISHA, TOYODA GOSEI CO., LTD.Inventors: Kenichi MITSUI, Katsuhisa Ota, Kaoru Itou
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Publication number: 20120146294Abstract: A boot seal for variable compression-rate engine includes a cylindrical boot-seal element, and a deformation inhibitor. The boot-seal element has an end being fixed to the cylinder block of the variable compression-rate engine, and another end being fixed to the crankcase. Moreover, the boot-seal element is provided with a bellows-shaped cylindrical deformer being made of an elastically deformable material. The deformation inhibitor is disposed outside or inside the boot-seal element in order to control the boot-seal element so as to deform outwardly or inwardly to a predetermined deformation magnitude.Type: ApplicationFiled: November 21, 2011Publication date: June 14, 2012Applicants: TOYOTA JIDOSHA KABUSHIKI KAISHA, TOYODA GOSEI CO., LTD.Inventors: Kenichi MITSUI, Katsuhisa OTA, Kaoru ITOU
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Publication number: 20090061299Abstract: A battery assembly includes single-battery cells, and thermally-conductive members. The thermally-conductive members are formed of a soft material as a plated configuration. The soft material exhibits thermal conductivity and electric insulatability. The single-battery cells, and the thermally-conductive members are adhered to each other, and are disposed one after another alternately in a row, thereby interposing the thermally-conducive members between the single-cell batteries. The thermally-conductive members include a radiation surface respectively from which heat that the single-battery cells produce radiates. The single-battery cells are cooled indirectly by cooling the radiation surfaces of the thermally-conductive members.Type: ApplicationFiled: July 31, 2008Publication date: March 5, 2009Applicant: TOYODA GOSEI CO., LTD.Inventors: Yasunori Uchida, Kimio Tsubaki, Shigeki Takeo, Hiroshi Onaka, Tatsuo Suzuki, Kenichi Mitsui
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Patent number: 7468169Abstract: This invention provides a production process, which can stably produce high-quality satin white (calcium trisulfoaluminate) having very small and homogeneous particulate shapes suitable for incorporation into coated paper for printing, and an apparatus for use in said process. In this process for producing calcium trisulfoaluminate, a calcium hydroxide suspension (A) is reacted with an aqueous aluminum sulfate solution (B) to produce calcium trisulfoaluminate (C). The aqueous aluminum sulfate solution (B) is added in plurality of stages to the calcium hydroxide suspension (A). At least any one stage of the plurality of stages addition, addition of the aqueous aluminum sulfate solution (B) to the calcium hydroxide suspension (A) is carried out in such a manner that the aqueous aluminum sulfate solution (B) is continuously added to the calcium hydroxide suspension (A) being continuously transferred.Type: GrantFiled: February 2, 2007Date of Patent: December 23, 2008Assignee: OJI Paper Co., Ltd.Inventors: Takayuki Kishida, Yuichi Ogawa, Yoshiki Kojima, Takuya Ono, Kenichi Mitsui, Tetsuya Hirabayashi, Masaki Nakano
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Publication number: 20080250923Abstract: A piston includes a piston body, an elastic adhesive layer, and a low thermal-conductivity sheet. The piston body has a piston top surface facing a combustion chamber, and exhibits a first thermal conductivity. The elastic adhesive sheet is formed on the piston top surface of the piston body, and includes a heat resistant resin. The low thermal-conductivity sheet is formed on the elastic adhesive layer, and exhibits a second thermal conductivity being lower than the first thermal conductivity of the piston body and falling in a range of from 5 or more to 40 W/m·K or less.Type: ApplicationFiled: March 27, 2008Publication date: October 16, 2008Applicants: TOYODA GOSEI CO., LTD., TOYOTA JIDOSHA KABUSHIKI KAISHAInventors: Kenichi Mitsui, Tatsuo Suzuki, Tadanobu Ota, Takao Suzuki, Hiroshi Onaka, Yasunori Uchida
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Publication number: 20070196264Abstract: This invention provides a production process, which can stably produce high-quality satin white (calcium trisulfoaluminate) having very small and homogeneous particulate shapes suitable for incorporation into coated paper for printing, and an apparatus for use in said process. In this process for producing calcium trisulfoaluminate, a calcium hydroxide suspension (A) is reacted with an aqueous aluminum sulfate solution (B) to produce calcium trisulfoaluminate (C). The aqueous aluminum sulfate solution (B) is added in plurality of stages to the calcium hydroxide suspension (A). At least any one stage of the plurality of stages addition, addition of the aqueous aluminum sulfate solution (B) to the calcium hydroxide suspension (A) is carried out in such a manner that the aqueous aluminum sulfate solution (B) is continuously added to the calcium hydroxide suspension (A) being continuously transferred.Type: ApplicationFiled: February 2, 2007Publication date: August 23, 2007Inventors: Takayuki Kishida, Yuichi Ogawa, Yoshiki Kojima, Takuya Ono, Kenichi Mitsui, Tetsuya Hirabayashi, Masaki Nakano
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Patent number: 7148911Abstract: Providing video telephone apparatus where the orientation of a picked-up image or a received image can be changed according to the orientation of the image pick-up section or the display, thus allowing transmission or display of a proper image at any time. In video telephone apparatus according to the invention, an image pick-up section outputs the image data on the target object to a transmit image rotating section. The transmit image rotating section performs rotation processing on a picked-up image so that the upper side of an image pick-up section in the vertical direction coincides with the upper side of an image to transmit to the distant party, based on the orientation of the image pick-up section detected by an image pick-up vertical direction detector. A picture signal received from the distant party is demodulated and output to a receive image rotating section.Type: GrantFiled: August 8, 2000Date of Patent: December 12, 2006Assignee: Matsushita Electric Industrial Co., Ltd.Inventors: Kenichi Mitsui, Toshiyuki Toda
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Patent number: 6991270Abstract: A hose coupling assembly wherein a hose 20 having a corrugated portion 22 is coupled to a fitting block 24 by a socket 50. The fitting block 24 has a block engagement catch 25c projecting from the outside rim of the block body 25. The socket 50 comprises a socket body 51 elastically expandable and contractible by being divided by a slit 51a, and a socket engagement catch 51b engages the block engagement catch 25c. To detach the socket 50 from the fitting block 24, force is applied in a rotation direction to a push operation portion 51c to cause the socket body 51 to undergo diametrical expansion, releasing the socket engagement catch 51b from the block engagement catch 25c.Type: GrantFiled: December 20, 2001Date of Patent: January 31, 2006Assignee: Toyoda Gosei, Co., Ltd.Inventors: Koji Ito, Naomi Nakashima, Kenichi Mitsui, Hiroshi Yamaguchi, Yoshiaki Kameda
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Patent number: 6889719Abstract: A plastic pipe 10 is a pipe utilized in a cooling water systems, and the bonding strength of each layer is heightened, and resistance capabilities of the antifreeze solution are enhanced. The plastic pipe 10 comprises an inner layer 22 formed from either a polyphenylene sulfide or an aromatic polysulfide, which is a denatured substance thereof, an intermediate layer 24, which is a mixture of PPS resin and a polyamide resin, and an outer layer 26 including a polyamide resin. The inner layer 22 is formed such that permeation of an antifreeze, which has mainly ethylene glycol, is less than 3.0 g/m2 per day. The resistance capabilities of the antifreeze solution can be achieved by making the thickness of the inner layer 22 0.2 mm or greater.Type: GrantFiled: July 3, 2002Date of Patent: May 10, 2005Assignee: Toyoda Gosei, Co., Ltd.Inventors: Norio Watanabe, Kenichi Mitsui
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Publication number: 20030099799Abstract: A resin hose for fuel in a plural-layer structure comprising a main body layer (14) made of aliphatic polyamide, and an inner tube layer (16) made of fluoroplastic disposed on the inner side of the main body layer (14). One or both of the aliphatic polyamide (aliphatic PA) and the fluoroplastic are respectively a modified aliphatic PA and a modified fluoroplastic. The characteristics of the both satisfy the requirements of a difference of melting point (DSC method) of 60° C. or less, and a difference of modulus of flexural elasticity (ASTM D 790) of 1500 MPa or less. Accordingly, the main body layer (14) and the inner tube layer (16) can be directly adhered to each other by co-extrusion.Type: ApplicationFiled: August 22, 2002Publication date: May 29, 2003Inventors: Masaki Koike, Kenichi Mitsui, Shinichi Eito, Daisuke Tsutsumi, Mitsutaka Kondo
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Patent number: 6523576Abstract: A fuel hose should reduce noise during fuel injection into an engine, and should not interfere with other engine components. The fuel hose supplies fuel drawn up from a fuel tank to the fuel injection valves of the engine, and is formed from a resin material which is resistant to fuel. The fuel hose comprises a hose main body having a fuel passage, and an non-circular component formed as a result of at least part of the cross sectional shape of the hose main body being non-circular. The non-circular component has a plurality of ribs running in the axial direction along the hose main body, and absorbs pulsation by the varying of the cross sectional shape of the ribs in response to variations in the pressure on the fuel flowing through the fuel passage, thereby resisting alterations to the shape in the axial direction.Type: GrantFiled: December 13, 2000Date of Patent: February 25, 2003Assignee: Toyoda Gosei Co., Ltd.Inventors: Tomohisa Imaeda, Kenichi Mitsui
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Publication number: 20030005973Abstract: A plastic pipe 10 is a pipe utilized in a cooling water systems, and the bonding strength of each layer is heightened, and resistance capabilities of the antifreeze solution are enhanced. The plastic pipe 10 comprises an inner layer 22 formed from either a polyphenylene sulfide or an aromatic polysulfide, which is a denatured substance thereof, an intermediate layer 24, which is a mixture of PPS resin and a polyamide resin, and an outer layer 26 including a polyamide resin. The inner layer 22 is formed such that permeation of an antifreeze, which has mainly ethylene glycol, is less than 3.0 g/m2 per day. The resistance capabilities of the antifreeze solution can be achieved by making the thickness of the inner layer 22 0.2 mm or greater.Type: ApplicationFiled: July 3, 2002Publication date: January 9, 2003Inventors: Norio Watanabe, Kenichi Mitsui
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Publication number: 20020093198Abstract: A hose coupling assembly wherein a hose 20 having a corrugated portion 22 is coupled to a fitting block 24 by a socket 50. The fitting block 24 has a block engagement catch 25c projecting from the outside rim of the block body 25. The socket 50 comprises a socket body 51 elastically expandable and contractible by being divided by a slit 51a, and a socket engagement catch 51b engages the block engagement catch 25c. To detach the socket 50 from the fitting block 24, force is applied in a rotation direction to a push operation portion 51c to cause the socket body 51 to undergo diametrical expansion, releasing the socket engagement catch 51b from the block engagement catch 25c.Type: ApplicationFiled: December 20, 2001Publication date: July 18, 2002Inventors: Koji Ito, Naomi Nakashima, Kenichi Mitsui, Hiroshi Yamaguchi, Yoshiaki Kameda
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Patent number: 6308992Abstract: A hose connecting assembly of the present invention ensures a tight seal even when a hose 30 is bent and laid out in a narrow space and repeatedly is subject to vibrations under a low-temperature condition. The hose connecting assembly includes a connection tube 10, which is pressed into the hose 30. The hose 30 is designed to have an inner diameter change rate Dc of no greater than 23% under application of an inner pressure of about 0.49 MPa. Ring-shaped projections 21, 22, and 23 are formed on the outer circumferential surface of the connection tube 10. The ring-shaped projections 21, 22, and 23 are designed to make a diameter expansion rate T, which is defined by an inner diameter d1 of the hose 30 and an outer diameter D2 of the ring-shaped projections 21, 22, and 23, at least 25%. A hollow cylindrical end 18 is further formed on an end portion of the connection tube 10. It is preferable that the hollow cylindrical end 18 has a length of at least about 3 mm.Type: GrantFiled: July 15, 1999Date of Patent: October 30, 2001Assignee: Toyoda Gosei Co., Ltd.Inventors: Kenichi Mitsui, Naomi Nakashima, Norio Watanabe, Koji Ito
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Publication number: 20010003995Abstract: A fuel hose should reduce noise during fuel injection into an engine, and should not interfere with other engine components. The fuel hose supplies fuel drawn up from a fuel tank to the fuel injection valves of the engine, and is formed from a resin material which is resistant to fuel. The fuel hose comprises a hose main body having a fuel passage, and an non-circular component formed as a result of at least part of the cross sectional shape of the hose main body being non-circular. The non-circular component has a plurality of ribs running in the axial direction along the hose main body, and absorbs pulsation by the varying of the cross sectional shape of the ribs in response to variations in the pressure on the fuel flowing through the fuel passage, thereby resisting alterations to the shape in the axial direction.Type: ApplicationFiled: December 13, 2000Publication date: June 21, 2001Inventors: Tomohisa Imaeda, Kenichi Mitsui