Abstract: The present invention provides a complex of an antigen and IgE binding to the antigen, a composition including an antigen and IgE binding to the antigen, and a method of using the complex or the composition to screen candidate therapeutics for TH-2 type diseases, for example in animal models.

Abstract: Disclosed are a magnetic resonance imaging apparatus and an RF pulse control method wherein an RF pulse sequence in a start-up sequence is set as a monotonically increasing flip angle with offset, in order to reduce ghosts, blurring, and other artifacts during measurement in a transient state. For example, the sum of two adjacent consecutive terms in a monotonically increasing sequence is set as the flip angle. Specifically, the number of RF pulses in the RF pulse sequence and the flip angle for the RF pulses in an SSFP sequence are set, and the monotonically increasing flip angle with offset is found, based on the set number of RF pulses in the RF pulse sequence and the flip angle for the RF pulses in the SSFP sequence, and used as the RF pulse sequence.

Abstract: An embodiment of the present invention provides an illuminating device that is disposed in an image-reading apparatus and image-forming equipment, including a light-source portion on one side; a light-source portion on the other side; and a long translucent light-guiding member having a light-discharging face long in a longitudinal direction thereof, and guiding light derived from the one light-source portion from one end face in the longitudinal direction, and light derived from the other light-source portion from the other end face in the longitudinal direction so that the guided light is irradiated to an object through the long light-discharging face; wherein the one and the other light-source portions are arranged such that positions of optical axes thereof differ from each other in a direction that is parallel to a light-irradiated face of the object and in a direction that is perpendicular to the longitudinal direction of the light-guiding member.

Abstract: In regard to a secured original method, an image reading apparatus provided in an image forming apparatus reads a first original guide using an original reading portion and, based on a reading result thereof, changes a reading position of an adjustment sheet in a main scanning direction to enable detection of a difference between a brightness of the first original guide and a brightness of the adjustment sheet. In regard to a moving original method, the image reading apparatus reads a reading member using the original reading portion and, based on a reading result thereof, changes a reading position of an adjustment sheet in a main scanning direction to enable detection of a difference between a brightness of the reading member and a brightness of the adjustment sheet.

Abstract: Luminance life can be enhanced in a vacuum fluorescent display that is driven according to a dynamic drive scheme and that uses a phosphor having remarkable luminance saturation. A drive method for a vacuum fluorescent display, having causing a phosphor layer formed on an anode to display under low-energy electron excitation by the dynamic driving, wherein the phosphor included in the phosphor layer is a phosphor in which the luminance increases when a pulse width is reduced under conditions in which the Du is kept the same in the dynamic driving, and in which, after a voltage is applied to the anode and the luminance of the phosphor is saturated, the time at which the luminance value decreases to 10% of the saturation luminance value following stoppage of the voltage application is 200 ?sec or more; and wherein the pulse width and pulse repetition period in the dynamic driving are made variable in the direction of maintaining the initial luminance of the phosphor as driving time elapses.

Abstract: In an inverted staggered type TFT (100), contact layers (150a and 150b) that electrically connect a channel layer (140) to source and drain electrodes (160a and 160b), respectively, include n+ amorphous silicon layers (151a and 151b), n+ microcrystalline silicon layers (152a and 152b), and n+ microcrystalline silicon layers (153a and 153b). The n+ microcrystalline silicon layers (152a and 152b) have a lower crystallization rate than the n+ microcrystalline silicon layers (153a and 153b) and are formed between the n+ amorphous silicon layers (151a and 151b) and the n+ microcrystalline silicon layers (153a and 153b). In this case, since the film thickness of incubation layers formed on surfaces of the n+ amorphous silicon layers (151a and 151b) decreases, the resistance value of the contact layers (150a and 150b) decreases. By this, the contact resistance of the TFT (100) decreases and the mobility can be increased.

Abstract: The present invention provides methods which use induction phenomenon of production of interleukin 18 (IL-18) from keratinocyte (KC), and their usages. The methods are preferably applicable for understanding of pathogenic mechanisms of atopic dermatitis (AD) and AD-like symptoms, and for development of therapeutic drugs for AD and AD-like symptoms. For example, by applying, on skin of mice or the like, protein A (SpA) derived from Staphylococcus aureus, or transplanting, on mice, a skin graft which has developed an inflammatory skin disease like AD, it is possible to reproduce elevation of IgE to high level in serum, which elevation is generated in an AD-like lesion. As a result, it is possible, for example, to screen for an inhibitor which inhibits induction of production of IL-18 from KC.

Abstract: An illuminating device capable of stably illuminating an irradiated object such as a document while suppressing light loss with a simply structure is provided. An LED array (71) and a reflective plate (73) are disposed sandwiching a slit (St) through which light reflected by a document MS passes and a light-guiding member (72) is disposed on the side of the LED array (71). The light-guiding member (72) includes a direct emission unit (77) disposed between an illumination range y centered on a document reading position and the LED array (71) and an indirect emission unit (78) disposed between the reflective plate (73) and the LED array (71), a light incidence face of the direct emission unit (77) and a light incidence face of the indirect emission unit (78) are disposed at mutually different position around the LED array (71), and the LED array (71) is disposed on a side of an interior angle formed by the light incidence faces.

Abstract: A drawing device draws a pattern on a substrate by radiating light from an optical head part on a target object (for example, substrate) which relatively moves with respect to the optical head part. Here, the optical head part has a spatial modulating unit which spatially modulates light from a light source, based on pattern data, and an optical path corrector which shifts the route of light spatially modulated in the spatial modulating unit at precision subdivided more than units of spatial modulation in the spatial modulating unit (more specifically, for example, units of pixels of spatial light modulator).

Abstract: A document reading section includes a document load table, a document load tray, a first document receiving tray, a linear conveyance path, a first guide member and a first reading section. The linear conveyance path, inclining downward from the document load tray, reaches the first document receiving tray. The first guide member is disposed in the linear conveyance path, and its top surface inclines downward along the linear conveyance path toward a downstream side in a document conveying direction in relation to the document load table. The first guide member is disposed in such a manner that part of its top surface intersects with a plane containing a top surface of the document load table.

Abstract: A transparent sheet is attached onto an inclined surface of an original guide plate of an image reading apparatus, and similarly, a transparent sheet is attached onto an inclined surface at an edge portion of a reading guide plate, thereby preventing an original from being chipped by the ground glass-like inclined surfaces and illumination light from being diffused by the ground glass-like inclined surfaces.

Abstract: An image reading apparatus comprises: an image reading unit that includes a platen glass and a color contact image sensor configured by a line image sensor for reading red, a line image sensor for reading green, and a line image sensor for reading blue, the line image sensors being disposed in a sub-scanning direction of an original; and an automatic original feeder. In the image reading apparatus, the line image sensor for reading red and the line image sensor for reading green are disposed so that a line gap therebetween is two lines, and in a monochrome mode in which a color original is read and output as a monochrome image, the color original is read using the line image sensor for reading red and the line image sensor for reading green.

Abstract: In a light source unit (210) serving as an embodiment of an illuminating apparatus, when P is a light-emitting element pitch [mm], and H is an optical axis distance [mm] between light-emitting elements (212) and an original (G), and when, in an illuminance cycle (T) representing repetition of bright and dark areas in a main scanning direction (X) on a light-irradiated face (Gs) of the original (G) caused by the light-emitting elements (212), the light-emitting element pitch (P) and the optical axis distance (H) are set such that unevenness [%] (M) (=(L1?L2)/L3 [%]) obtained by dividing a value obtained by subtracting a minimum illuminance value (L2) from a maximum illuminance value (L1) by an average illuminance value (L3) and an inter-unevenness distance [mm] (N) which is a half cycle of the illuminance cycle (T) satisfy the relation M?N/2?5.5, and more preferably, M?N/2?7.5.

Abstract: A plate on which a channel pattern is formed, which channel pattern includes a first channel into which a buffer agent is injected, and a second channel having, in a portion thereof, a quantification part that has a portion common to the first channel and holds a predetermined amount of a biological sample, the biological sample being injected into the channel including the quantification part, and the plate is rotated at a high speed by a filling unit to fill the buffer agent in the first channel, and thereafter, the second channel is pressurized by a discrimination unit to fill the biological sample in the second channel, and simultaneously, a predetermined amount of the biological sample is added into the buffer agent. Therefore, when performing discrimination of the biological sample, a discrimination result can be obtained accurately in a short time without the necessity of complicated preparation works.

Abstract: The present invention provides a complex of an antigen and IgE binding to the antigen, a composition including an antigen and IgE binding to the antigen, and a method of using the complex or the composition. With the present invention, it is possible to induce naive T cells to develop into Th2 cells. Moreover, the present invention clarified a working mechanism of a Th2-type immune response, particularly a production mechanism of early IL-4. With use of the present invention, it is possible to provide a technique of treating and preventing Th2-type diseases.

Abstract: The present invention provides an illuminating device including a plurality of light-emitting elements arranged in a line, the illuminating device illuminates an irradiation target by irradiating the irradiation target with light that is emitted from the light-emitting elements via a first and a second optical paths. In the illuminating device, a light diffusing portion for diffusing light is provided in one of the first optical path and the second optical path, and an irradiation light amount of said one of the first optical path and the second optical path in which the light diffusing portion is provided is larger than an irradiation light amount of the other optical path.

Abstract: An image reading apparatus includes a reading glass, a second guide member, and a control section. The reading glass and the second guide member together form a document feed path. The second guide member includes a white reference plate. The control section performs, when it is determined that shading correction image data is affected by a stain, a stain location determination of whether the stain is attached to the reading glass or the second guide member according to a tone value variation in the portion of the shading correction image data that corresponds to the stain edge, the variation being along a predetermined distance in the main scanning direction.

Abstract: An image reading apparatus of the present invention includes a photoelectric transducer that performs reading scanning along a main scanning line and reads an original, the image reading apparatus obtaining a white shading level of pixels based on an output level of the photoelectric transducer obtained when a reference white is read, obtaining a black shading level of the pixels based on an output level of the photoelectric transducer obtained when a black reference is read or obtained in a dark condition, and correcting the output level of the photoelectric transducer obtained when an original image is read with the use of the white shading level and the black shading level, and the image reading apparatus further comprising a correction unit that obtains a variation amount of the white shading level between a pixel and other pixels in the vicinity of that pixel for each of pixels on the main scanning line, determines whether the variation amount exceeds a pre-set threshold value, and when the correction un

Abstract: An illuminating device (210) according to an embodiment of the invention included in an image reading apparatus (100) and an image forming apparatus (D) includes light source portions (211a1), (211b1), (211a2) and (211b2), light-guiding members (213a) and (213b) for illuminating an illumination target (G) from an elongated light emitting face (M) that extends in a longitudinal direction (Y), by guiding light from the light source portions, and holding members (216a) and (216b) for holding the light-guiding members. The holding members include holding portions (2161a) and (2161b) for removably holding the light-guiding members, and tilted portions (2162a) and (2162b) that reflect light emitted from the light emitting face (M), the tilted portions extending from a front end on the light emitting face (M) side of the holding portions, obliquely widening with increasing distance from the light-guiding members.

Abstract: An illuminating device includes a light-emitting element that is mounted on a base material and a light-guiding member that guides light from the light-emitting element to an irradiation target, and illuminates the irradiation target with the light transmitted through the light-guiding member. The light-guiding member includes an extending portion that extends from the surface of the base material on which the light-emitting element is mounted to a left side end portion of the base material so as to cover the left side end portion. An image-reading includes this illuminating device. Image-forming apparatus includes this image-reading apparatus.