Abstract: This invention provides compounds having antiviral activities especially inhibiting activity for influenza virus, more preferably provides substituted 3-hydroxy-4-pyridone derivatives having cap-dependent endonuclease inhibitory activity.

Abstract: This invention provides compounds having antiviral activities especially inhibiting activity for influenza virus, more preferably provides substituted 3-hydroxy-4-pyridone derivatives having cap-dependent endonuclease inhibitory activity.

Abstract: A clutch mechanism includes a transmission element rotatable in a first direction and a second direction opposite to the first direction, integrally including a plurality of projections including a first planar surface and a second planar surface at each side of the projections in the direction of rotation of the transmission element, a rotation restriction device including a first restriction surface and a second restriction surface to contact the first planar surface and the second planar surface, to lock rotation of the transmission element, and a moving device including an actuator to move the rotation restriction device to contact and separate from the transmission element. The first restriction surface contacts the first planar surface while the transmission element rotates in the first direction, and the second restriction surface contacts the second planar surface while the transmission element rotates in the second direction.

Abstract: A drive unit, which can be included in an image forming apparatus with peripherals disposed thereto and use a control method therefore, includes an inner rotor brushless DC motor, a driver, a rotation detector, and a controller. The driver supplies power to drive the brushless DC motor. The rotation detector detects an amount and direction of rotations of an output shaft. The controller controls the rotations of the brushless DC motor and obtains a target drive signal of the brushless DC motor externally and a detection signal from the rotation detector and outputs a signal to the driver. The controller controls a speed of rotation of the brushless DC motor by varying the signal output to the driver based on the target drive signal and the detection signal.

Abstract: The present invention provides a novel compound having an antiviral action, in particular, an HIV replication inhibiting action, as well as a pharmaceutical composition, in particular, an anti-HIV agent. wherein, a broken line means the presence or absence of a bond; R1 is substituted or unsubstituted alkyl etc., R2 is substituted or unsubstituted alkyloxy etc.; n is 1 or 2; R3 is a substituted or unsubstituted aromatic carbocyclic group; R4 is a hydrogen atom etc.; R5 is a substituted or unsubstituted aromatic carbocyclic group etc.; Y is a single bond etc.; R6 is substituted or unsubstituted alkyl; R7 is —Z—R71 etc.; Z is —NR72—CO— etc.; R71 is substituted or unsubstituted alkyl etc.; R72 is a hydrogen atom etc.

Abstract: In a power converter, a feedback controller feedback controls a manipulated variable based on a first electrical parameter depending on input power and a feedback controlled variable determined for output power. A dead-time determiner determines a value of the dead time as a function of a boundary condition variable depending on at least one of the input power and the output power. The boundary condition represents a reference for determining whether the power converter is operating in a continuous conduction mode or a discontinuous conduction mode. The continuous conduction mode is designed for a current to be continuously flowing through an inductor included in the power converter or a load as an inductor current. The discontinuous conduction mode is designed for the inductor current to be discontinuously flowing through the inductor.

Abstract: A drive unit, which can be included in an image forming apparatus with peripherals disposed thereto and use a control method therefore, includes an inner rotor brushless DC motor, a driver, a rotation detector, and a controller. The driver supplies power to drive the brushless DC motor. The rotation detector detects an amount and direction of rotations of an output shaft. The controller controls the rotations of the brushless DC motor and obtains a target drive signal of the brushless DC motor externally and a detection signal from the rotation detector and outputs a signal to the driver. The controller controls a speed of rotation of the brushless DC motor by varying the signal output to the driver based on the target drive signal and the detection signal.

Abstract: A DC-DC converter generates PWM signals PWM1H, PWM1L on the basis of a reference signal CLK1 to drive switching elements connected in series. When generating a reset signal RST, the converter generates PWM signals PWM2H, PWM2L on the basis of the reset signal RST. When generating no reset signal, the converter generates the PWM signals PWM2H, PWM2L on the basis of a reference signal CLK2 in order to drive other switching elements connected in series. The converter generates the reset signal RST at an optional timing to the reference signal CLK1. The reference signal CLK2 is brought forward from the reference signal CLK1 by ?T1. The PWM signals PWM1H, PWM1L are different in timing from the PWM signals PWM2H, PWM2L. This makes it possible to avoid the switching elements diagonally arranged from being simultaneously turned on and off, and suppress a switching loss, and to increase an efficiency of the converter.

Abstract: The present invention provides a metastin derivative represented by the formula (I): wherein each symbol is as defined in the specification, or a salt thereof, or a pharmaceutical composition containing it. The metastin derivative or a salt thereof is superior in blood stability, and has a cancer metastasis suppressive action or cancer growth suppressive action.

Abstract: A clutch mechanism comprises a planetary gear unit including input transmission, output transmission, and transmission stopping members. Torque entering the input transmission member is outputted downstream of the planetary gear unit by the output transmission member when the transmission stopping member is fixed and is not outputted downstream when the transmission stopping member is unfixed and entering a rotatable state. A rotation prohibiting target has an engaging target and is integral with the transmission stopping member. A rotation prohibiting member has a supporting shaft, a swingable portion at its one end and an engaging portion at its other end to engage the engaging target to enable the transmission stopping member to exert the stopping function. The engaging portion disengages the engaging target to bring the transmission stopping member into an unfixed state. A damper unit absorbs vibration caused in the rotation prohibiting member during a switching operation.

Abstract: The present invention provides a compound having antiviral effects, particularly having growth inhibitory activity on influenza viruses, a preferred example of the compound being a substituted 3-hydroxy-4-pyridone derivative prodrug having cap-dependent endonuclease inhibitory activity.

Abstract: A clutch mechanism includes a transmission element rotatable in a first direction and a second direction opposite to the first direction, integrally including a plurality of projections including a first planar surface and a second planar surface at each side of the projections in the direction of rotation of the transmission element, a rotation restriction device including a first restriction surface and a second restriction surface to contact the first planar surface and the second planar surface, to lock rotation of the transmission element, and a moving device including an actuator to move the rotation restriction device to contact and separate from the transmission element. The first restriction surface contacts the first planar surface while the transmission element rotates in the first direction, and the second restriction surface contacts the second planar surface while the transmission element rotates in the second direction.

Abstract: An object of the present invention is to provide a novel integrase inhibitor. The present invention relates to a novel compound having an antiviral effect, more specifically, a pyridone derivative having HIV integrase inhibitory activity, and a medicament containing the same, in particular, an anti-HIV agent. The compound of the present invention has integrase inhibitory activity and/or cell proliferation inhibitory activity against viruses, in particular, HIV and drug-resistant strains thereof. Thus, the compound is useful in preventing or treating various diseases, viral infections (for example, AIDS), and the like in which integrase participates.

Abstract: An image forming apparatus includes a first image carrier facing an intermediate transfer belt, a primary transfer unit primarily transferring images on the first image carrier onto the intermediate transfer belt, a secondary transfer roller facing the intermediate transfer belt secondarily transferring images on the intermediate transfer belt onto a recording medium, a second image carrier provided upstream/downstream of a secondary transfer position in a recording medium conveying direction, a direct transfer unit directly transferring images on the second image carrier onto the recording medium, a recording medium carriage belt rotatably stretched across roller members including the secondary transfer roller supporting and conveying the recording medium to pass a direct transfer position and the secondary transfer position, and a displacement unit displacing the secondary transfer roller between a contact position where the recording medium carriage belt contacts the intermediate transfer belt and a separa

Abstract: An image forming apparatus includes a primary transfer device that primarily transfers a first image from a first image bearer onto a first belt unit at a primary transfer position, a secondary transfer device that secondarily transfers the first image from the first belt unit onto a printing medium at a secondary transfer position, and a direct transfer device that directly transfers a second image from a second image bearer onto the printing medium at a direct transfer position. A second belt unit is rotatably suspended by plural second rollers and carries and conveys the printing medium through the direct transfer position and the secondary transfer position. An interval between the direct transfer position and the secondary transfer position is prescribed natural number times of a circumference of one of the plural second rollers, which fluctuates a velocity of the second belt unit.

Abstract: This invention provides compounds having antiviral activities especially inhibiting activity for influenza virus, more preferably provides substituted 3-hydroxy-4-pyridone derivatives having cap-dependent endonuclease inhibitory activity.

Abstract: The present invention provides a compound represented by the following formula (1); wherein R1 is an aryl group etc.; R2 is —CO—NH— etc.; R3 is a methyl group having an aromatic group or a cycloalkyl group; R4 is a hydrogen atom etc.; R5 is a methyl group having an aromatic group; and R6 is an amino group or an N-alkyl substituted amino group, having a low-molecular weight and a superior GPR54 agonist activity, and a pharmaceutical composition containing the compound.

Abstract: A drive unit, which can be included in an image forming apparatus with peripherals disposed thereto and use a control method therefore, includes an inner rotor brushless DC motor, a driver, a rotation detector, and a controller. The driver supplies power to drive the brushless DC motor. The rotation detector detects an amount and direction of rotations of an output shaft. The controller controls the rotations of the brushless DC motor and obtains a target drive signal of the brushless DC motor externally and a detection signal from the rotation detector and outputs a signal to the driver. The controller controls a speed of rotation of the brushless DC motor by varying the signal output to the driver based on the target drive signal and the detection signal.

Abstract: An image forming apparatus includes a first image carrier facing an intermediate transfer belt, a primary transfer unit primarily transferring images on the first image carrier onto the intermediate transfer belt, a secondary transfer roller facing the intermediate transfer belt secondarily transferring images on the intermediate transfer belt onto a recording medium, a second image carrier provided upstream/downstream of a secondary transfer position in a recording medium conveying direction, a direct transfer unit directly transferring images on the second image carrier onto the recording medium, a recording medium carriage belt rotatably stretched across roller members including the secondary transfer roller supporting and conveying the recording medium to pass a direct transfer position and the secondary transfer position, and a displacement unit displacing the secondary transfer roller between a contact position where the recording medium carriage belt contacts the intermediate transfer belt and a separa

Abstract: An object of the present invention is to provide a photoelectric conversion device having a high power generation efficiency. A photoelectric conversion device includes a light-transmitting conductive part including a light incident surface and a light output surface, a semiconductor part formed on the light output surface, an anti-reflection coating formed on the semiconductor part, and a dye-sensitized photoelectric conversion body including a charge transport part and a dye that receives a charge from the charge transport part. The charge transport part is in contact with the anti-reflection coating. The anti-reflection coating has a bandgap larger than that of the semiconductor part.