Abstract: Method and system for purifying a sample comprising a biomolecule of interest and impurities, comprising expressing said biomolecule of interest in a bioreactor to form a product sample comprising said biomolecule of interest and impurities; subjecting said product sample to filtration to form a clarified product sample; subjecting said clarified product sample to affinity chromatography to remove impurities; subsequently subjecting said product sample to diafiltration followed by virus filtration and optional concentration. The buffer used during the diafiltration step (and thus in the virus filtration step) is the buffer desired for the final formulation of the product.

Abstract: An gaming machine for and method of par-mutuel wagering that allows individuals to continuously place multiple casino and lottery styled pari-mutuel wagers on simulcast live and/or recorded pari-mutuel race events. The gaming machine includes a display screen to provide a graphic display of a plurality of pari-mutuel gaming options to a player, and a selection device operable by the player to select at least one of the pari-mutuel gaming options displayed on the screen, the selection device operable by the player to input a wager corresponding to the selected at least one pari-mutuel gaming option. The gaming machine has the ability to be linked to a network of gaming machines in pari-mutuel and/or other wagering venues.

Abstract: A system can include a first housing that includes a processor and memory accessible to the processor; a second housing that includes a display operatively coupled to the processor; a hinge Fassembly that rotatably couples the first housing and the second housing, where the hinge assembly includes permanent magnets that generate a first magnetic field and a second magnetic field orientable with respect to each other via rotation of the second housing with respect to the first housing, where the first magnetic field and the second magnetic field include an aligned orientation, generate a clockwise restoring torque responsive to rotation in a first rotational direction from the aligned orientation, and generate a counterclockwise restoring torque responsive to rotation in a second, opposite rotational direction from the aligned orientation.

Abstract: An industrial integrated development environment (IDE) supports collaborative tools that allow multiple designers and programmers to remotely submit design input to the same automation system project in parallel while maintaining project consistency. The industrial IDE also permits localized development of system projects, and provides an infrastructure for intelligently brokering between conflicting edits submitted to common portions of the system project. To facilitate effective collaboration via efficient communication between developers, the IDE system can be configured to send push notifications to personal client devices in response to relevant events originating within the development environment relating to development of an automation system project.

Abstract: The disclosed technology includes a collar that can output a first corrective action having a first correction magnitude, detect feedback information, and determine a second correction magnitude based at least in part on the feedback information. The collar can output a second corrective action responsive to determining that the collar is within a predetermined distance from an adverse device. The collar can receive map data and automatically determine a first geographical area in which it is permissible for a collar to be located and/or a second geographical area in which it is impermissible for the collar to be located, the collar being related to the system.

Abstract: The disclosed technology includes a pet collar that can be configured to determine its geolocational position and evaluate that position with respect to the geo-fence of a predetermined, geo-fenced “safe” zone. If the collar determines that its position is inside a safe zone but is near the geo-fence, the collar may be configured to provide a warning correction. If the collar determines that it is outside a predetermined safe zone, the collar can also be configured to provide a stronger correction to discourage the pet from continuing away from the safe zone. The collar may also be configured to guide the pet back to the safe zone such as by varying the strength and/or type of correction provided based at least in part on the distance of the collar from the geo-fence.

Abstract: The present invention relates to an inhaler comprising: an assembly including a heater element arranged in the inhaler to be proximal to a substrate region configured for supporting a vapour or atomiser precursor substrate; wherein the assembly is configured such that the heater element is operative to achieve and maintain a target temperature in the substrate region throughout a period corresponding to a plurality of consecutive uses of the inhaler.

Abstract: The disclosed technology includes a pet collar that can be configured to determine its geolocational position and evaluate that position with respect to the geo-fence of a predetermined, geo-fenced “safe” zone. If the collar determines that its position is inside a safe zone but is near the geo-fence, the collar may be configured to provide a warning correction. If the collar determines that it is outside a predetermined safe zone, the collar can also be configured to provide a stronger correction to discourage the pet from continuing away from the safe zone. The collar may also be configured to guide the pet back to the safe zone such as by varying the strength and/or type of correction provided based at least in part on the distance of the collar from the geo-fence.

Abstract: The present invention solves some of the problems of the prior art by providing a method, system and apparatus for readily refilling the reservoir of a smoking-substitute device with liquid from a dispenser. The method, system and apparatus of the present invention prevents liquid from being dispensed until the dispenser is securely and sealably engaged to the smoking-substitute device, provides independent liquid and gas pathways between the dispenser and reservoir, and substantially alleviates the problems of spillage and/or leakage when dispensing liquid from the dispenser into the reservoir of the smoking-substitute device.

Abstract: A device and method of transferring energy between peer devices includes determining a predefined limit on energy transfer to a consumer device, initiating transfer of the energy via an energy transfer connection, and terminating the energy transfer when the predefined limit is reached.

Abstract: Examples described herein relate to a system consistent with the disclosure. For instance, the system may comprise a printing device including hardware to form an image on a print medium, a memory resource, and a controller to receive a print job to form the markings on the print medium, designate a pixel of the received print job to form a covert dot pattern on the markings, where the pixel corresponds to a first laser intensity level; and adjust a laser intensity of the printing device to a second laser intensity level based on the first laser intensity level of the designated pixel to form the covert dot pattern.

Abstract: Various implementations include systems for processing audio signals. In particular implementations, a system for processing audio signals includes: an accessory device that includes a first processor for running a machine learning model on an input signal, where the machine learning model includes a classifier configured to generate metadata associated with the input signal; and a wearable audio device configured for wireless communication with the accessory device, the wearable audio device including a second processor that utilizes the metadata from the accessory device to process a source audio signal and output a processed audio signal.

Abstract: Disclosed are example embodiments of a sectional interlocking plant support system providing a stand for supporting growing plants in soil comprising a stake and a pole, coupled to the stake or other devices, the pole comprising a porous tubular body, the porous tubular body formed by a plurality of porous openings on the pole, the pole configured to be stackable on a second pole, the height being adjustable be selecting a number of poles to connect together. The porous openings on the pole comprising at least one hole shaped in at least one of a circle, a triangle, a square, a hexagon, a pentagon, a heptagon, an octagon, a nonagon, a polygon having more than nine sides, or a irregular shape.

Abstract: Method and apparatus for creating a fluid communication line in a downhole environment between an annular chamber and a throughbore of a tool. The tubular wall therebetween is provided with circumferentially arranged recesses extending into the wall to provide selected thin-walled sections for perforation by a communication tool. The communication tool has two oppositely arranged punch heads, one aligned with a recess and the other between neighbouring recesses giving an orientationless configuration in operation. An embodiment for creating a fluid communication line through a tubing retrievable safety valve for operation of a wireline retrievable safety valve located therein is described.

Abstract: An example processing station for registering a passenger's luggage for a trip is provided, the processing station comprising: an injector for receiving a piece of luggage associated with the passenger; at least one sensor associated with the injector for sensing whether the dimensions of the piece of luggage exceed a predetermined limit; a weighing machine associated with the injector for weighing the piece of luggage whilst in the injector; a controller associated with the at least one sensor and weighing machine, the controller being adapted to accept the piece of luggage if feedback from the at least one sensor and weighing machine indicate that dimensions and weight of the piece of luggage are within respective predetermined limits; and an injector conveyor in the floor of the injector for conveying the piece of luggage in a first direction, if accepted, to a downstream collector conveyor system.

Abstract: An assembly may include a speaker supportable for movement relative to a reference external to the speaker and a speaker housing supporting speaker components operable to produce an audio output. A sensor is operable to sense a direction of movement of the speaker during movement of the speaker relative to the reference. Control components are operable to control the speaker components based on the direction of movement of the speaker relative to the reference. When the speaker is sensed to be moving in a first direction relative to the reference, an operational characteristic of the speaker components is controlled to increase or advance during movement in the first direction. When the speaker is sensed to be moving in a second direction relative to the reference different from the first direction, the operational characteristic of the speaker components is controlled to decrease or retreat during movement in the second direction.

Abstract: Methods and uses for controlling non-crop pests (especially of the orders Blattodea, Diptera, Hemiptera, Hymenoptera, Isoptera, Orthoptera) and/or populations of social insects and non-social solitary or gregarious insects, especially ants, wasps, termites and cockroaches, with a carboxamide compound and its mixtures, and compositions comprising it, are disclosed.

Abstract: The present invention relates to a dispenser for dispensing a liquid, comprising: a reservoir for storing a liquid to be dispensed; a manually operative pump arrangement disposed at a first end region of the reservoir; a conduit extending from the pump arrangement to a second end region of the reservoir distal the first end region, the conduit configured for communicating reservoir contents from the second end region to the pump arrangement; a dispense conduit extending from the pump arrangement and comprising a dispense aperture at an end region thereof, the dispense aperture in liquid communication with the pump arrangement; and an open ended tube extending in a direction away from the pump arrangement and configured to surround the dispense conduit, wherein the open ended tube extends to a position such that the open end thereof is at least coterminous with an dispense aperture end of the dispense conduit and actuation of the pump arrangement causes transfer of reservoir contents from the reservoir to the

Abstract: A system can include a first housing that includes a processor and memory accessible to the processor; a second housing that includes a display operatively coupled to the processor; a hinge assembly that rotatably couples the first housing and the second housing, where the hinge assembly includes permanent magnets that generate a first magnetic field and a second magnetic field orientable with respect to each other via rotation of the second housing with respect to the first housing, where the first magnetic field and the second magnetic field include an aligned orientation, generate a clockwise restoring torque responsive to rotation in a first rotational direction from the aligned orientation, and generate a counterclockwise restoring torque responsive to rotation in a second, opposite rotational direction from the aligned orientation.

Abstract: Various implementations include systems for processing audio signals. In particular implementations, a system for processing audio signals includes: a wearable audio device having a transducer and a communication system; and an accessory device configured to wirelessly communicate with the wearable audio device, the accessory device having a processor configured to process a source audio signal according to a method that includes: source separating the source audio signal; and providing a source separated audio signal to the wearable audio device for transduction.