Abstract: The present novel technology relates to an autologous cell therapy that comprises a pre-determined amount of a processed bone marrow cellular matrix with a pre-determined amount of pre-mixture, where the pre-mixture includes quantities of anticoagulant solution, dextrose and phosphate buffered saline, and methods for production. The present novel technology further relates to a method of using the composition to reduce discogenic pain in humans.

Abstract: A winder for winding a web to produce a rolled product is provided. The winder includes a web transport apparatus that is used for conveying the web. Also included in one exemplary embodiment is a plurality of independent winding modules. The winding modules are independently positioned to independently engage the web as the web is conveyed by the web transport apparatus. The winding modules may be configured to wind the web to form a rolled product by center winding, surface winding, and combinations of center and surface winding. The winding modules are structurally and operationally independent of one another where if one module is disabled, another may still operate to produce the rolled product without shutting down the winder.

Abstract: Invented is a method of inhibiting the activity/function of PI3 kinases using quinoline derivatives. Also invented is a method of treating one or more disease states selected from: autoimmune disorders, inflammatory diseases, cardiovascular diseases, neurodegenerative diseases, allergy, asthma, pancreatitis, multiorgan failure, kidney diseases, platelet aggregation, cancer, sperm motility, transplantation rejection, graft rejection and lung injuries by the administration of quinoline derivatives.

Abstract: Embodiments of the present disclosure are also directed to a web-configuration system that includes at least one processor and one or more tangible, machine-readable media at least collectively including or storing instructions executable by the at least one processor. The instructions include a module configured to limit configuration options for a welding system based on user selection of a power source for the welding system, a module configured to calculate a weld cable size for the welding system based on the user selection of the power source and user selection of an input voltage, a module configured to assign weld cable characteristics based on the weld cable size and a user selected cable length, and a module configured to assemble a welding system order based at least on the user selection of the power source and the weld cable characteristics.

Abstract: Herein are disclosed indoles of formula (I) where the various groups are defined herein, and which are useful for treating cancer.

Abstract: A winder for winding a web to produce a rolled product is provided. The winder includes a web transport apparatus that is used for conveying the web. Also included in one exemplary embodiment is a plurality of independent winding modules. The winding modules are independently positioned to independently engage the web as the web is conveyed by the web transport apparatus. The winding modules may be configured to wind the web to form a rolled product by center winding, surface winding, and combinations of center and surface winding. The winding modules are structurally and operationally independent of one another where if one module is disabled, another may still operate to produce the rolled product without shutting down the winder.

Abstract: A two-dimensional machine-readable code is provided on a non-electronic, encoded tangible medium of a hardcopy implement. The two-dimensional machine-readable code encodes first tier data of a multi-tiered data set, and is readable by a reading mechanism of a mobile communication device. Access by the mobile communication device from the first tier data to second tier data of the multi-tiered data set is then determined and enabled, where the second tier data is stored with the first tier data on an electronic, tangible, machine-readable storage medium.

Abstract: A micromixing chamber, roughly in the form of an hourglass, having a first outer end with a tangential inflow opening and a second outer end with a tangential outflow opening. The mixing chamber in the overall flow direction first narrows more or less gradually and subsequently widens more or less abruptly. The micromixer may be made at least partially of glass, or at least partially of a plurality of glass plates. A micromixer having a plurality of such micromixing chambers connected fluidically in series is also disclosed. Methods for manufacturing such a micromixing chamber of such a micromixer, as well as method for mixing by means of such a micromixing chamber or by means of such a micromixer, are disclosed.

Abstract: A method of fabricating a microelectronic unit can include providing a semiconductor element having front and rear surfaces, a plurality of conductive pads each having a top surface exposed at the front surface and a bottom surface remote from the top surface, and a first opening extending from the rear surface towards the front surface. The method can also include forming at least one second opening extending from the first opening towards the bottom surface of a respective one of the pads. The method can also include forming a conductive via, a conductive interconnect, and a contact, the conductive via in registration with and in contact with the conductive pad and extending within the second opening, the contact exposed at an exterior of the microelectronic unit, the conductive interconnect electrically connecting the conductive via with the contact and extending away from the via at least partly within the first opening.

Abstract: The present invention relates to a automated spraying device for spraying an enclosure with a liquid cleanser, the device having, a reservoir (16) for containing the liquid cleanser, a pump (14) in fluid communication with the reservoir, and a movable spray head (15) having an outlet orifice through which cleanser from the reservoir can be expelled during operation of the pump if there is such liquid cleanser in the reservoir. Said spraying device also contains an electrical motor drive mechanism (12) for sequentially operating th pump (14) and moving the spray head (15) to modify the direction of the spray there from, such that the spray head is not simultaneously spraying and moving. Furthermore, the spray head is suitable for producing an aerosol whereby the Dv50 of the aerosol is in the range of from 30 to 70 micron.

Abstract: A method of machine control can include providing at least a system master signal, selectively synchronizing at least sub-system master signal to the system master signal based on the value of the system master signal, and carrying out at least one operation based on the value of the other master signal. For example, a machine controller may provide a system virtual master signal and synchronize one or more module virtual master signals to the system virtual master based on the system virtual master count value. One or more components of the module may operate based on the count value of the module virtual master signal. The use of an asynchronous control method may advantageously increase the flexibility of the machine. Because the operation of the components of the machine may depend on respective virtual master signals, a machine using asynchronous control methods may advantageously continue operating one component or module in the event of a fault involving other components.

Abstract: Disclosed is a Social-Topical Adaptive Networking (STAN) system that can inform users of cross-correlations between currently focused-upon topic or other nodes in a corresponding topic or other data-objects organizing space maintained by the system and various social entities monitored by the system. More specifically, one of the cross-correlations may be as between the top N now-hottest topics being focused-upon by a first social entity and the amounts of focus ‘heat’ that other social entities (e.g., friends and family) are casting on the same topics (or other subregions of other cognitive attention receiving spaces) in a relevant time period.

Abstract: A fiber optic connector assembly includes a connector and a carrier. The connector has a first mating end and a second end and a first optical fiber terminated thereto. The fiber defines a first end adjacent the mating end and a second end protruding from the second end of the connector. A polymeric carrier having a connector end and an oppositely disposed cable end is engaged with the connector. The carrier includes a heat activated meltable portion adjacent the cable end. An alignment structure is disposed on the carrier that includes a first end, a second end, and a throughhole. The first end of the alignment structure is for receiving the second end of the first optical fiber and the second end of the alignment structure is for receiving an end of a second optical fiber entering the cable end of the carrier.

Abstract: A method of protecting wood through enhanced penetration of wood preservatives includes providing a solution including (a) at least one amine oxide, (b) at least one organic wood preservative and (c) a non-borate buffering based agent. The solution has a pH of 5 to 12.4 and preferably about 7 to 10. The solution is applied to the surface of the wood after which, with or without intervening storage, the materials are activated to effect enhanced penetration of the organic wood preservative into the wood. One may effect application at a solution temperature of about 30° C. to 75° C. and preferably about 50° C. to 60° C. to effect activation at a higher temperature and high relative humidity. In a preferred practice, the wood may be heated before and/or after application of the solution. The solution is also disclosed as a product.

Abstract: Coreless tissue rolls can be produced without having to use an adhesive to form a hollow center. Instead, moisture can be used to promote light hydrogen bonding between the layers of the tissue web that line the hollow center. The hydrogen bonding provides sufficient structure to maintain the shape of the hollow center without rendering the tissue web surrounding the passageway unusable. Passageways can also be formed in accordance with the present disclosure that are substantially circular so that the rolls will easily spin on a spindle. In an alternative embodiment, moisture is not used in constructing the wound tissue roll.

Abstract: A microelectronic package including a dielectric layer having top and bottom surfaces, the dielectric layer having terminals exposed at the bottom surface; a metallic wall bonded to the dielectric layer and projecting upwardly from the top surface of the dielectric layer and surrounding a region of the top surface; a metallic lid bonded to the wall and extending over the region of the top surface so that the lid, the wall and the dielectric layer cooperatively define an enclosed space; and a microelectronic element disposed within the space and electrically connected to the terminals.

Abstract: This disclosure relates generally to welding, and more specifically, to submerged arc welding (SAW). In an embodiment, a welding system includes a gas supply system configured to provide a gas flow. The system also includes a wire supply system configured to provide welding wire, and a flux supply system configured to provide flux near a welding arc during submerged arc welding (SAW). The system further includes a welding torch assembly configured to receive the gas flow and the welding wire and to deliver the gas flow and the welding wire near the welding arc during SAW.

Abstract: This disclosure relates generally to welding, and more specifically, to submerged arc welding (SAW). In an embodiment, a welding system includes a gas supply system configured to provide a fluorine-containing gas flow. The system also includes a wire supply system configured to provide welding wire, and a flux supply system configured to provide flux near a welding arc during submerged arc welding (SAW). The system further includes a welding torch assembly configured to receive the fluorine-containing gas flow and the welding wire and to deliver the fluorine-containing gas flow and the welding wire near the welding arc during the SAW.

Abstract: An assembly includes a connector and a carrier engaged therewith. Connector has a first mating end and a second end and a first fiber. The fiber defines a first end adjacent the mating end and a second end protruding from the connector second end. Carrier has a connector end and an opposite cable end and includes a heat activated meltable portion adjacent the cable end. An alignment structure is on the carrier and includes first and second ends, and a throughhole. The first end of the alignment structure receives the second end of the first fiber and the second end receives an end of a second fiber entering the carrier. The heat activated portion melts and assumes a flowable condition when exposed to a predetermined amount of heat and resolidifies when heat is removed, bonding the second fiber to the carrier after the first and second fibers are aligned.

Abstract: The present invention provides a conductive substrate useful for Joule heating, such as in an electronic smoking article. Particularly, the invention provides a resistive heating element formed of a conductive substrate. The conductive substrate comprises an electrically conductive material and a carbonaceous additive, such as a binder material. The conductive substrate is carbonized in that it is subjected to calcining conditions to effectively reduce the carbonaceous additive to its carbon skeleton. It has been found that such carbonized substrate has surprisingly improved resistance properties in relation a substrate of the same formulation that is not carbonized. The carbonized substrate can include an aerosol precursor material. The formed resistive heating element can be included in an electronic smoking article to simultaneously provide resistive heating and aerosol formation with a single, unitary component.