Abstract: This disclosure relates generally to welding, and more specifically, to submerged arc welding (SAW). In an embodiment, a welding system includes a gas supply system configured to provide a fluorine-containing gas flow. The system also includes a wire supply system configured to provide welding wire, and a flux supply system configured to provide flux near a welding arc during submerged arc welding (SAW). The system further includes a welding torch assembly configured to receive the fluorine-containing gas flow and the welding wire and to deliver the fluorine-containing gas flow and the welding wire near the welding arc during the SAW.

Abstract: A data security incident correlation and dissemination system and method is disclosed. In an exemplary implementation of the system, a service provider of a managed security service receives incident information regarding data security incidents at different business organizations of the security service. One or more incident managers operated by different organizations send incident information, and a server system within the service provider's network creates aggregated data from the incident information received from the incident managers. The server system analyzes the aggregated data to create correlated incident records that include incident information from related data security incidents at the different organizations, and provides threat intelligence data based on the correlated incident records for the organizations. In embodiments, the server system can “push” threat intelligence data to the organizations, or the organizations can request the threat intelligence data from the server system.

Abstract: Systems and methods for managing shared collections are described. For example, a machine receives a textual description of an entry requested to be created within a collection at a network-based system. The textual description is submitted by a user of the network-based system and received from a client device of the user by a server system within the network-based system. The entry, when created, corresponds to an item listed by the network-based system. The machine generates a structured description of the entry based on the textual description of the entry requested to be created. The structured description of the entry includes a name-value pair derived from the textual description submitted by the user. The machine determines that the entry is absent from the network-based system, and creates the entry within the collection by storing the structured description of the entry in a database of the network-based system.

Abstract: Described herein are melanocortin analogs having enhanced activity and transport.

Abstract: A system and method for responding to data security incidents in enterprise networks using an incident response bus (IR bus) within an incident management system is disclosed. An Incident Manager (IM) application of the system stores objects that include information concerning data security incidents that occur in enterprise networks managed by the incident management system. Users configure action conditions on the IM, the satisfaction of which cause the IM to send messages that include the information concerning the incidents to message queues, or destinations. Correspondingly, the IR bus includes plugins associated with the devices in each client's enterprise network, where each plugin can access the message destinations for the messages. The plugins, in one embodiment, also configure one or more chains of plugins that process the messages. The plugins then execute the chains of plugins to specify actions for the devices to execute to provide a response to the incidents.

Abstract: This invention relates to novel compounds according to Formula (I) which are inhibitors of Enhancer of Zeste Homolog 2 (EZH2), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy for the treatment of cancers.

Abstract: Described herein are melanocortin analogs having enhanced activity and transport.

Abstract: Solutions for killing weeds include a herbicide admixed with a buffered amine oxide. The synergism between the two components reduces the amount of herbicide which must be employed to achieve an effective weed kill. Related methods involve application of the solution to the weeds to be killed.

Abstract: This invention relates to novel compounds according to Formula (I) which are inhibitors of Enhancer of Zeste Homolog 2 (EZH2), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy for the treatment of cancers.

Abstract: In one example, a data center may be built in modular components that may be pre-manufactured and separately deployable. Each modular component may provide functionality such as server capacity, cooling capacity, fire protection, resistance to electrical failure. Some components may be added to the data center by connecting them to the center's utility spine, and others may be added by connecting them to other components. The spine itself may be a modular component, so that spine capacity can be expanded or contracted by adding or removing spine modules. The various components may implement functions that are part of standards for various levels of reliability for data centers. Thus, the reliability level that a data center meets may be increased or decreased to fit the circumstances by adding or removing components.

Abstract: Solutions for killing weeds include a herbicide admixed with a buffered amine oxide. The synergism between the two components reduces the amount of herbicide which must be employed to achieve an effective weed kill. Related methods involve application of the solution to the weeds to be killed.

Abstract: The present invention relates to a solution for resisting destruction of living plants and a related method. A solution including a buffered amine oxide admixed with at least one material selected from the group consisting of insecticides and fungicides is applied to the living plant and provides a synergistically effective greater resistance to living plant deterioration than any of the individual buffered amine oxide, insecticides and fungicide achieve considered individually. A related method is disclosed.

Abstract: The present invention relates to a solution for resisting destruction of living plants and a related method. A solution including a buffered amine oxide admixed with at least one material selected from the group consisting of insecticides and fungicides is applied to the living plant and provides a synergistically effective greater resistance to living plant deterioration than any of the individual buffered amine oxide, insecticides and fungicide achieve considered individually. A related method is disclosed.

Abstract: The present invention relates to a automated spraying device for spraying an enclosure with a liquid cleanser, the device having,—a reservoir (16) for containing the liquid cleanser,—a pump (14) in fluid communication with the reservoir, and—a movable spray head (15) having an outlet orifice through which cleanser from the reservoir can be expelled during operation of the pump if there is such liquid cleanser in the reservoir. Said spraying device also contains an electrical motor drive mechanism (12) for sequentially operating th pump (14) and moving the spray head (15) to modify the direction of the spray there from, such that the spray head is not simultaneously spraying and moving. Furthermore, the spray head is suitable for producing an aerosol whereby the Dv50 of the aerosol is in the range of from 30 to 70 micron.

Abstract: The present novel technology relates to an autologous cell therapy that comprises a pre-determined amount of a processed bone marrow cellular matrix with a pre-determined amount of pre-mixture, where the pre-mixture includes quantities of anticoagulant solution, dextrose and phosphate buffered saline, and methods for production. The present novel technology further relates to a method of using the composition to reduce discogenic pain in humans.

Abstract: Herein are disclosed indoles of formula (I) where the various groups are defined herein, and which are useful for treating cancer.

Abstract: This invention relates to novel compounds according to Formula (I) which are inhibitors of Enhancer of Zeste Homolog 2 (EZH2), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy for the treatment of cancers.

Abstract: Coreless tissue rolls can be produced without having to use an adhesive to form a hollow center. Instead, moisture can be used to promote light hydrogen bonding between the layers of the tissue web that line the hollow center. The hydrogen bonding provides sufficient structure to maintain the shape of the hollow center without rendering the tissue web surrounding the passageway unusable. Passageways can also be formed in accordance with the present disclosure that are substantially circular so that the rolls will easily spin on a spindle. In an alternative embodiment, moisture is not used in constructing the wound tissue roll.

Abstract: An incident manager application (IM) for responding to data security incidents in enterprise networks is disclosed. An IM tracks the incidents in an enterprise network by storing incident objects and incident artifact (IA) metadata created for the incidents, where the incident objects and IAs include information concerning the incidents. Incident response team (IRT) personnel of the enterprise networks can define action conditions within the IM that are associated with the incident objects. When the information within the incident objects and/or IAs meets the defined action conditions, the IM includes the objects that cause the action conditions to be satisfied in messages. Devices such as user account databases and configuration servers within the enterprise network can then download the messages and execute actions that reference the objects extracted from the downloaded messages to implement a response to the incidents.

Abstract: This invention relates to novel compounds according to Formula (I) which are inhibitors of Enhancer of Zeste Homolog 2 (EZH2), to pharmaceutical compositions containing them, to processes for their preparation, and to their use in therapy for the treatment of cancers.