Abstract: A biocompatible, polymeric composition is disclosed. The composition comprises a base polymer comprising (i) a prepolymer comprising para-dioxanone (PDO) and trimethylene carbonate (TMC); and (ii) an end-graft polymer chain comprising a polylactone. Also disclosed are a method for treating bleeding from bone or bony structures using the composition, a method for filling a void or correct a defect in a bone using the composition, and a method for producing the biocompatible, polymeric composition of the present application.

Abstract: The invention is directed to certain novel compounds directed to compounds of formula (I) and salts thereof. The compounds of the invention are inhibitors of PI3-kinase activity.

Abstract: The present disclosure provides systems and methods for testing an integrated circuit or device under test (DUT). A DUT of the present invention has a plurality of scan chains, a plurality of shift register elements each associated with a respective one of the scan chains, and a programmable switch matrix to configure shift register elements of a subset of the plurality of shift register elements to cause one shift register element of the subset to receive an interleaved test sequence, and to cause the interleaved test sequence to be shifted to other shift register elements in the subset, and to input deinterleaved test sequences to scan chains associated with the subset.

Abstract: An apparatus, system, and method are disclosed for generating contact plans and responding to web form inquires using the contact plans.

Abstract: The present invention is directed to compounds for use in the treatment or prevention of influenza virus infection.

Abstract: The present invention extends to methods, systems, and computer program products for creating and manipulating custom compound data types in declarative programs. The present invention allows a developer to create and use custom compound data types without requiring the custom type to be specifically defined (e.g. via registering a custom assembly) in the underlying framework. This is accomplished by providing a data container that is configurable to represent virtually any combination of primitive or compound types defined within the framework. The present invention also provides a declarative model for interacting with data containers representing custom compound data types. This declarative model employs a path-based syntax (or other type of syntax) for accessing the elements of a custom compound data type. Multiple paths can be defined within a single unit of developer input so that multiple elements of a custom data type can be manipulated by the single unit of input.

Abstract: Bioactive, hydroforming luminal liner compositions are formed of high molecular weight crystalline, absorbable copolyesters dissolved in a liquid derivative of a polyether glycol that undergoes transformation into a tissue-adhering, resilient interior cover or liner for the controlled release of its bioactive payload at clinically compromised conduits in humans as in the case of bacteria- and yeast-infected vaginal canals, esophagi, and arteries following angioplasty.

Abstract: Equol (7-hydroxy-3(4?hydroxyphenyl)-chroman), the major metabolite of the phytoestrogen daidzein, specifically binds and blocks the hormonal action of 5?-dihydrotestosterone (DHT) in vitro and in vivo. Equol can bind circulating free DHT and sequester it from the androgen receptor, thus altering growth and physiological hormone responses that are regulated by androgens. These data suggest a novel model to explain equol's biological properties. The significance of equol's ability to specifically bind and sequester DHT from the androgen receptor have important ramifications in health and disease and may indicate a broad and important usage for equol in the treatment and prevention of androgen-mediated pathologies. Thus, equol can specifically bind DHT and prevent DHT's biological actions in physiological and pathophysiological processes.

Abstract: Sending or receiving messages in a host agnostic way in a continuation based runtime. A method includes defining a contract between a continuation based runtime and host for sending or receiving a message. The contract defines one or more of: details about what should be included in the messages, operations for sending the message; operations for receiving the message, parameters for cancellation of inflight operations, or notifications about correlation information lifetime. The method further includes identifying a correlation handle. The correlation handle uniquely identifies an executing instance of an activity. The method further comprises identifying a bookmark. The bookmark defines where the continuation based runtime should resume after sending or receiving the message. The method further comprises calling the contract using the correlation handle and the bookmark to allow the message to be correctly routed by the host and for the continuation based runtime to be correctly resumed.

Abstract: A method for preparing an enantiomeric chromane, by asymmetrically hydrogenating a chromene compound in the presence of an Ir catalyst having a chiral ligand. The method includes the enantioselective preparation of enantiomeric equol. A preferred Ir catalyst has a chiral phosphineoxazoline ligand. Enantiomeric chromanes of high stereoselective purity can be obtained.

Abstract: An in situ film-forming methyl acetate-based solution of at least one absorbable, segmented block copolymer with amorphous and semi-crystalline segments contains at least one bioactive agent which exhibits antimicrobial, anti-inflammatory, antiviral, anesthetic, hemostatic, and/or antineoplastic activity. The absorbable polymers can be a polyaxial copolyester, polyether-ester and polyether-ester urethane. The solution can be applied (e.g., sprayed or swabbed) onto animal and human skin or accessible body cavities to prevent or treat one or more disorders preventable or treatable by the bioactive agent therein.

Abstract: A female urine collection device, system and method are provided. The device includes a support device and a urine collection bag. The urine collection bag encapsulates the upper surface and sides of the support device, thus keeping the support device out of the path of the urine during urination. The support device is compact and sturdy so as to be capable of use and, if desired, of reuse.

Abstract: A trailer hitch system for equalizing trailer loads and reducing trailer sway. The trailer hitch system may include spring bars that may be attached to a hitch head using a trunnion style connection. The spring bars may be attached to the trailer using rigid brackets that reduce swinging of the spring bars. The rigid brackets having a plurality of contact points may include an upward extending portion for attaching to the trailer tongue, and a lateral extending portion for receiving the spring bars thereupon.

Abstract: Bioactive, hydroforming luminal liner compositions are formed of high molecular weight crystalline, absorbable copolyesters dissolved in a liquid derivative of a polyether glycol that undergoes transformation into a tissue-adhering, resilient interior cover or liner for the controlled release of its bioactive payload at clinically compromised conduits in humans as in the case of bacteria- and yeast-infected vaginal canals, esophagi, and arteries following angioplasty.

Abstract: An apparatus, system, and method are disclosed for providing web-based phone services. Phone calls are initiated by a user control on a web page. A calling module uniquely identifies the telephone call and initiates calling by a dialer. Once the telephone call is established, auxiliary functions such as call monitoring, recording, transfer, or conference calling may be initiated for the call. Additional controls corresponding to the auxiliary functions may provided on the web page or a related web page. The web pages used to provide the user controls may stateless web pages.

Abstract: Technologies for enabling a continuation based runtime to accept or reject external stimulus and, in addition, to determine if an external stimulus may be valid for processing at a later point in execution.

Abstract: A method and a printing implementing the method for dynamic printer performance tuning. The method includes the steps of processing a page to be printed by a printer description language interpreter to generate a Display List, selecting tuning parameters from the Display List data, analyzing the tuning parameters by a Bayesian analyzer to obtain a score for each tuning parameter, and based on the score of each tuning parameter, adjusting rendering settings of the tuning parameters for printing the page. The steps of training the Bayesian analyzer includes creating a set of training pages, rendering each page to determine best performance settings for each tuning parameter, grouping the pages based on tuning parameter settings, generating Display List data of each page, rendering the training pages in each group to compile training data that are saved for future printing jobs.

Abstract: The present invention extends to using Simple Object Access Protocol (“SOAP”) to exchange typed objects, such as, for example, parameters for invoking methods. A computer system accesses typed object parameters corresponding to a typed object. The typed object is annotated with one or more message contract attributes of a message contract model defining a mapping between typed object parameters and corresponding SOAP elements. The computer system utilizes the message contract attributes to map the typed object parameters into a SOAP element and inserts the SOAP element into a SOAP envelope. A receiving computer system accessing the SOAP element and utilizes the message contract attributes to map the SOAP element back into the typed object parameters.

Abstract: Equol (7-hydroxy-3(4?hydroxyphenyl)-chroman), the major metabolite of the phytoestrogen daidzein, specifically binds and blocks the hormonal action of 5?-dihydrotestosterone (DHT) in vitro and in vivo. Equol can bind circulating free DHT and sequester it from the androgen receptor, thus altering growth and physiological hormone responses that are regulated by androgens. These data suggest a novel model to explain equol's biological properties. The significance of equol's ability to specifically bind and sequester DHT from the androgen receptor have important ramifications in health and disease and may indicate a broad and important usage for equol in the treatment and prevention of androgen-mediated pathologies. Thus, equol can specifically bind DHT and prevent DHT's biological actions in physiological and pathophysiological processes.

Abstract: The invention is directed to certain novel compounds. Specifically, the invention is directed to compounds of formula (I): and salts thereof. The compounds of the invention are inhibitors of PI3-kinase activity.