Patents by Inventor Kenneth Hillan
Kenneth Hillan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20050014226Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.Type: ApplicationFiled: August 13, 2004Publication date: January 20, 2005Inventors: Avi Ashkenazi, Kevin Baker, David Botstein, Luc Desnoyers, Dan Eaton, Napoleone Ferrara, Ellen Filvaroff, Sherman Fong, Wei-Oiang Gao, Hanspeter Gerber, Mary Gerritsen, Audrey Goddard, Paul Godowski, J. Grimaldi, Austin Gurney, Kenneth Hillan, Ivar Kljavin, Sophia Kuo, Mary Napier, James Pan, Nicholas Paoni, Margaret Roy, David Shelton, Timothy Stewart, Daniel Tumas, P. Williams, William Wood
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Publication number: 20050003487Abstract: The present invention is directed to secreted and transmembrane polypeptides and to nucleic acid molecules encoding those polypeptides.Type: ApplicationFiled: July 27, 2004Publication date: January 6, 2005Inventors: Dan Eaton, Audrey Goddard, Paul Godowski, J. Grimaldi, Austin Gurney, Kenneth Hillan, William Wood
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Publication number: 20040043397Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.Type: ApplicationFiled: April 7, 2003Publication date: March 4, 2004Applicant: Genentech, Inc.Inventors: Jian Chen, Ellen Filvaroff, Sherman Fong, Audrey Goddard, Paul Godowski, Christopher Grimaldi, Austin Gurney, Hanzhong Li, Kenneth Hillan, Daniel Tumas, Menno VanLookeren, Richard Vandlen, Colin K. Watanabe, P. Mickey Williams, William I. Wood, Daniel Yansura
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Publication number: 20030203451Abstract: The present invention is directed to novel polypeptides having sequence identity with IL-17, IL-17 receptors and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treating degenerative cartilaginous disorders and other inflammatory diseases.Type: ApplicationFiled: June 10, 2003Publication date: October 30, 2003Applicant: Genentech, Inc.Inventors: Jian Chen, Ellen Filvaroff, Sherman Fong, Audrey Goddard, Paul Godowski, J. Christopher Grimaldi, Austin Gurney, Hanzhong Li, Kenneth Hillan, Sarah G. Hymowitz, Daniel Tumas, Melissa A. Starovasnik, Menno VanLookeren, Richard Vandlen, Colin Watanabe, P. Mickey Williams, William I. Wood, Daniel Yansura
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Publication number: 20030199044Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.Type: ApplicationFiled: April 8, 2003Publication date: October 23, 2003Applicant: Genentech, Inc.Inventors: Jian Chen, Ellen Filvaroff, Sherman Fong, Audrey Goddard, Paul Godowski, Christopher Grimaldi, Austin Gurney, Hanzhong Li, Kenneth Hillan, Daniel Tumas, Menno VanLookeren, Richard Vandlen, Colin Watanabe, P. Mickey Williams, William I. Wood, Daniel Yansura
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Publication number: 20030186306Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.Type: ApplicationFiled: April 8, 2003Publication date: October 2, 2003Applicant: Genentech, Inc.Inventors: Jian Chen, Ellen Filvaroff, Sherman Fong, Audrey Goddard, Paul J. Godowski, Christopher Grimaldi, Austin Gurney, Hanzhong Li, Kenneth Hillan, Daniel Tumas, Menno VanLookeren, Richard Vandlen, Colin Watanabe, P. Mickey Williams, William I. Wood, Daniel Yansura
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Publication number: 20030180255Abstract: The present invention is directed to novel polypeptides having sequence identity with IL-17, IL-17 receptors and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treating degenerative cartilaginous disorders and other inflammatory diseases.Type: ApplicationFiled: April 9, 2003Publication date: September 25, 2003Applicant: Genentech, Inc.Inventors: Jian Chen, Ellen Filvaroff, Sherman Fong, Audrey Goddard, Paul Godowski, Christopher Grimaldi, Austin Gurney, Hanzhong Li, Kenneth Hillan, Daniel Tumas, Menno VanLookeren, Richard Vandlen, Colin Watanabe, P. Mickey Williams, William I. Wood, Daniel Yansura
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Patent number: 6579520Abstract: The present invention is directed to novel polypeptides having sequence identity with IL-17, IL-17 receptors and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treating degenerative cartilaginous disorders and other inflammatory diseases.Type: GrantFiled: March 22, 2001Date of Patent: June 17, 2003Assignee: Genentech, Inc.Inventors: Jian Chen, Ellen Filvaroff, Sherman Fong, Audrey Goddard, Paul Godowski, Christopher Grimaldi, Austin Gurney, Hanzhong Li, Kenneth Hillan, Daniel Tumas, Menno VanLookeren, Richard Vandlen, Colin Watanabe, P. Mickey Williams, William I. Wood, Daniel Yansura
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Patent number: 6569645Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.Type: GrantFiled: December 20, 2000Date of Patent: May 27, 2003Assignee: Genentech, Inc.Inventors: Jian Chen, Ellen Filvaroff, Sherman Fong, Audrey Goddard, Paul Godowski, Christopher Grimaldi, Austin Gurney, Hanzhong Li, Kenneth Hillan, Daniel Tumas, Menno VanLookeren, Richard Vandlen, Colin Watanabe, P. Mickey Williams, William I. Wood, Daniel Yansura
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Patent number: 6551822Abstract: The present invention concerns isolated nucleic acid molecules encoding the novel TIE ligands NL1, NL5, NL8, and NL4, the proteins encoded by such nucleic acid molecules, as well as methods and means for making and using such nucleic acid and protein molecules.Type: GrantFiled: December 8, 1998Date of Patent: April 22, 2003Assignee: Genentech, Inc.Inventors: Paul J. Godowski, Austin L. Gurney, Kenneth Hillan, David Botstein, Audrey Goddard, Margaret Roy, Napoleone Ferrara, Daniel Tumas, Ralph Schwall
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Publication number: 20030054442Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.Type: ApplicationFiled: July 18, 2001Publication date: March 20, 2003Applicant: GENENTECH, INC.Inventors: Jian Chen, Ellen Filvaroff, Sherman Fong, Audrey Goddard, Paul J. Godowski, J. Christopher Grimaldi, Austin Gurney, Hanzhong Li, Kenneth Hillan, Daniel Tumas, Menno VanLookeren, Richard Vandlen, Colin K. Watanabe, P. Mickey Williams, William I. Wood, Daniel Yansura
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Publication number: 20030008815Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.Type: ApplicationFiled: December 20, 2000Publication date: January 9, 2003Applicant: GENENTECH, INC.Inventors: Jian Chen, Ellen Filvaroff, Sherman Fong, Audrey Goddard, Paul J. Godowski, Christopher Grimaldi, Austin L. Gurney, Hanzhong Li, Kenneth Hillan, Daniel Tumas, Menno VanLookeren, Richard Vandlen, Colin Watanabe, P. Mickey Williams, William I. Wood, Daniel G. Yansura
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Publication number: 20030003546Abstract: The present invention is directed to novel polypeptides having sequence identity with IL-17, IL-17 receptors and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treating degenerative cartilaginous disorders and other inflammatory diseases.Type: ApplicationFiled: March 22, 2001Publication date: January 2, 2003Applicant: GENENTECH, INC.Inventors: Jian Chen, Ellen Filvaroff, Sherman Fong, Audrey Goddard, Paul Godowski, Christopher Grimaldi, Austin Gurney, Hanzhong Li, Kenneth Hillan, Daniel Tumas, Menno VanLookeren, Richard Vandlen, Colin Watanabe, P. Mickey Williams, William I. Wood, Daniel Yansura
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Publication number: 20020177188Abstract: The present invention is directed to novel polypeptides having sequence identity with IL-17, IL-17 receptors and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Further provided herein are methods for treating degenerative cartilaginous disorders and other inflammatory diseases.Type: ApplicationFiled: June 5, 2001Publication date: November 28, 2002Applicant: GENENTECH, INC.Inventors: Jian Chen, Ellen Filvaroff, Sherman Fong, Audrey Goddard, Paul J. Godowski, J. Christopher Grimaldi, Austin Gurney, Hanzhong Li, Kenneth Hillan, Sarah G. Hymowitz, Daniel Tumas, Melissa A. Starvovasnik, Menno Van Lookeren, Richard Vandlen, Colin Watanabe, P. Mickey Williams, William I. Wood, Daniel G. Yansura
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Patent number: 6350450Abstract: The present invention concerns isolated nucleic acid molecules encoding the novel TIE ligands NL1, NL5 and NL8, the proteins encoded by such nucleic acid molecules, as well as methods and means for making and using such nucleic acid and protein molecules.Type: GrantFiled: August 19, 1998Date of Patent: February 26, 2002Assignee: Genentech, Inc.Inventors: Paul J. Godowski, Austin L. Gurney, Audrey Goddard, Kenneth Hillan
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Patent number: 6348351Abstract: The present invention concerns isolated nucleic acid molecules encoding the novel TIE ligand homologues NL2, NL3 and NL6 (FLS139), the proteins encoded by such nucleic acid molecules, as well as methods and means for making and using such nucleic acid and protein molecules.Type: GrantFiled: December 8, 1998Date of Patent: February 19, 2002Assignee: Genentech, Inc.Inventors: Sherman Fong, Napoleone Ferrara, Audrey Goddard, Paul J. Godowski, Austin L. Gurney, Kenneth Hillan, P. Mickey Williams
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Publication number: 20020012961Abstract: The present invention is directed to novel polypeptides having homology to the PRO533 protein and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention, and methods for producing the polypeptides of the present invention. The invention concerns compositions and methods for the diagnosis and treatment of neoplastic cell growth and proliferation in mammals, including humans. The invention is based on the identification of genes that are amplified in the genome of tumor cells. Such gene amplification is expected to be associated with the overexpression of the gene product and contribute to tumorigenesis and/or autocrine signaling.Type: ApplicationFiled: April 15, 1999Publication date: January 31, 2002Applicant: Genentech, Inc.Inventors: DAVID BOTSTEIN, AUSTIN L GURNEY, AUDREY GODDARD, KENNETH HILLAN, DAVID A LAWRENCE, MARGARET ANN ROY
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Patent number: 6074873Abstract: The present invention concerns isolated nucleic acid molecules encoding the novel TIE ligand homologues NL2, NL3 andNL6 (FLS139), the proteins encoded by such nucleic acid molecules, as well as methods and means for making and using such nucleic acid and protein molecules.Type: GrantFiled: August 28, 1998Date of Patent: June 13, 2000Assignee: Genentech, Inc.Inventors: Sherman Fong, Napoleone Ferrara, Audrey Goddard, Paul J. Godowski, Austin L. Gurney, Kenneth Hillan, P. Mickey Williams