Abstract: Disclosed are nucleic acid oligomer compounds and to their use in compositions and methods for inhibiting proliferation, survival or viability of cancer cells including prostate, lung, pancreatic, breast, cervical and bone cancer cells.

Abstract: The present disclosure relates to cancer and more particularly, methods of treating and/or determining the responsiveness to treatment and/or prognosis of cancers, such as lung cancer and breast cancer.

Abstract: A modular liquid-cooled thermal heat sink device configured to thermally engage with a thermal substrate. The device comprises a housing assembly having a body defining a volume, the housing assembly comprising a thermal cooling plate configured to be in thermal contact with the thermal substrate, a fluid inlet and a fluid outlet, the housing assembly being configured to facilitate fluid circulation within the body to effect an operative cooling of the thermal substrate through the thermal cooling plate, the body comprising a plurality of first engaging features spaced about a perimeter of the body.

Abstract: An improved liquid vaporization and conditioning system, and associated method, for efficiently vaporizing a liquid sample for accurately determining the constituent components thereof providing enhanced flow rate, pressure and thermal control, the improvement including a combination of a resistance temperature detector, a sweeping bend to, an in-line thermal break, a flow buffering input manifold, enhanced multi-path heater vaporizer construction with four heater units, a vaporizer output mixing manifold and control elements providing a capability for partial shutdown in the event of compromised heating or flow anomalies without risk of flow loss/volume capacity beyond a permissible threshold and an improved, modular heat vaporizer enclosure.

Abstract: Artifacts, including parameters are data sets, associated with experiment tasks are stored at an experiment management service. A query specifying a particular value of a parameter and a particular data set is received, and an indication of an experiment result associated with the particular data set and the particular parameter value is provided.

Abstract: Disclosed are nucleic acid oligomer compounds and to their use in compositions and methods for inhibiting proliferation, survival or viability of cancer cells including prostate, lung, pancreatic, breast, cervical and bone cancer cells.

Abstract: A cooling device for cooling electronic components comprising a primary electronic component, and one or more secondary electronic components of a circuit board is provided. The cooling device comprises a first cooling component. The first cooling component comprises a first cooling member configured to contact a surface of the primary electronic component. The first cooling member is configured to be in fluid communication with a fluid to effect an operative convection cooling of the surface of the primary electronic component. The cooling device further comprises a second cooling component. The second cooling component comprises a second cooling member configured to contact a respective thermal surface of the one or more secondary electronic components to effect an operative conduction cooling of the one or more secondary electronic components. The second cooling member is thermally coupled to the first cooling member.

Abstract: An ocean iron fertilization (OIF) method and system for electrochemically controlled release of iron in an ocean to stimulate growth of phytoplankton to increase CO2 sequestration by the ocean. The system includes a cathode submerged or floating in the ocean; an iron or iron-producing anode submerged or floating in the ocean spaced apart from the cathode; and a power supply unit connected to the cathode and the anode. The power supply unit drives electric current between the cathode and the anode such the anode generates oxygen (O2) and ferrous iron through electrolysis to be released in the ocean, and the cathode produces hydrogen (H2) and hydroxide (OH—) species through an electrochemical reaction at the cathode.

Abstract: A shaft coupling for connecting an upper shaft with a lower shaft within a pumping system is designed to handle a large tensile load between the upper and lower shafts. In some embodiments, the upper shaft includes a shaft ring groove and the coupling has a body and a first receiving chamber within the body that receives an end of the upper shaft. The coupling also includes an upper internal groove extending into the body from the first receiving chamber and an upper split ring that is configured to be compressed into a position occupying both the upper internal groove and the shaft ring groove of the upper shaft. Set screws compress the upper split ring into the shaft ring groove of the upper shaft. In another embodiment, the coupling includes a plurality of locking screws that extend through the body into corresponding lock screw grooves in the upper and lower shafts.

Abstract: A multi-stage pressure regulation system, device and associated methodology for reducing the pressure of gas passing through a gas sample conditioning system. The device and method allow for automatic and/or manual configuration settings for regulating different types of gas having different profiles while still avoiding dew point dropout thereby ensuring accurate sample analysis at a downstream analyzer. The pressure regulating device includes a housing having a core, a vapor sample input port, a plurality of openings on an upper surface, a plurality of pressure regulating valves configured to reduce the pressure of a vapor sample, and an assembly having a base and substantially central stem orthogonal to the base and extending axially therefrom, the stem being disposed within the core.

Abstract: An improved liquid vaporization and conditioning system, and associated method, for efficiently vaporizing a liquid sample for accurately determining the constituent components thereof providing enhanced flow rate, pressure and thermal control, the improvement including a combination of a resistance temperature detector, a sweeping bend to, an in-line thermal break, a flow buffering input manifold, enhanced multi-path heater vaporizer construction with four heater units, a vaporizer output mixing manifold and control elements providing a capability for partial shutdown in the event of compromised heating or flow anomalies without risk of flow loss/volume capacity beyond a permissible threshold and an improved, modular heat vaporizer enclosure.

Abstract: Artifacts, including parameters are data sets, associated with experiment tasks are stored at an experiment management service. A query specifying a particular value of a parameter and a particular data set is received, and an indication of an experiment result associated with the particular data set and the particular parameter value is provided.

Abstract: A multi-stage pressure regulation system, device and associated methodology for reducing the pressure of gas passing through a gas sample conditioning system. The device and method allow for automatic and/or manual configuration settings for regulating different types of gas having different profiles while still avoiding dew point dropout thereby ensuring accurate sample analysis at a downstream analyzer. The pressure regulating device includes a housing having a core, a vapor sample input port, a plurality of openings on an upper surface, a plurality of pressure regulating valves configured to reduce the pressure of a vapor sample, and an assembly having a base and substantially central stem orthogonal to the base and extending axially therefrom, the stem being disposed within the core.

Abstract: Disclosed are nucleic acid oligomer compounds and to their use in compositions and methods for inhibiting proliferation, survival or viability of cancer cells including prostate, lung, pancreatic, breast, cervical and bone cancer cells.

Abstract: A system and method for substantially coincidental sample takeoff flow rate verification which detects unstable flow conditions in a pipeline, terminates fluid sample analysis during flow instability, and resumes sample takeoff when a steady flow state is re-established.

Abstract: A vaporizer device and associated methodology for providing accurate sampling through substantially efficient, complete and uniform single pass vaporization of a liquid sample by avoiding liquid pre-vaporization and downtime attributable to system damage from incomplete vaporization, particularly in the distribution, transportation, and custody transfer of natural gas. The vaporizer device includes at least one input port for receiving a liquid sample, a channel for directing the liquid to a vaporizer core and a heating assembly within the vaporizer core configured to flash vaporize the liquid sample. The vaporized sample can then be passed to an outlet for sample analysis.

Abstract: Basement shoring apparatus has a modular panel having a panel body having a plurality of parallel drill rod shafts therethrough. Each drill rod shaft has a respective drill rod rotatably engaged therein. Each drill rod extends from a lower edge of the panel body and has a respective auger or cutting head attached at a distal end thereof. Each drill rod is connectable via an upper edge of the panel body for turning. Adjacent drill rods extend to different extent such that blades of respective augers overlap adjacently. As such, modular panel can be drilled into the ground to form shoring wall.

Abstract: The present disclosure generally provides topically applicable insect repelling compositions, and in some embodiments, topically applicable insect repelling and UV protecting compositions. The compositions comprise a polymerization product of a polyol, a diisocyanate and at least one insect-repelling compound. The resulting polymers advantageously bond superficially to skin or hair, thereby localizing repellents and preventing systemic absorption. While not being bound by theory, it is believed that the localization of repellents to the surface of the skin renders them safer, wherein such repellents are not vaporized and do not have a disagreeable odor. The repellents advantageously interact with tactile insect activity, thereby preventing parasitic activity, such as drawing blood or the communication of pathogens.