Abstract: Compounds of the formula ##STR1## wherein R is thienyl, mono-, di- and trihalothienyl, furyl, 2-benzothiazolyl, pyridyl or chloropyridyl and their pharmaceutically acceptable salts are useful agents for combating fungal infections in animals, including humans.

Abstract: Triazole antifungal agents of the formula: ##STR1## and their O-esters and O-ethers, where R is a phenyl group optionally substituted by 1 to 3 substituents each independently selected from halo, CF.sub.3, C.sub.1 -C.sub.4 alkyl and C.sub.1 -C.sub.4 alkoxy; R.sup.1 is selected from (a) ##STR2## (C.sub.1 -C.sub.4 alkyl), (b) --SO.sub.2 (C.sub.1 -C.sub.4 alkyl), (C) --SO.sub.2 NR.sup.2 R.sup.3 where either R.sup.2 and R.sup.3 are both C.sub.1 -C.sub.4 alkyl, or R.sup.2 and R.sup.3 together with the N atom to which they are attached represent piperidino, (d) --NHSO.sub.2 (C.sub.1 -C.sub.4 alkyl) and (e) --CONR.sup.4 R.sup.5 where either R.sup.4 is H or C.sub.1 -C.sub.4 alkyl and R.sup.5 is C.sub.1 -C.sub.4 alkyl, or R.sup.4 and R.sup.5 together with the N atom to which they are attached represent piperidino;and n is 1 or 2 with the proviso that n is 2 when R.sup.1 is --NHSO.sub.2 (C.sub.1 -C.sub.4 alkyl);and their pharmaceutically acceptable salts. The compounds are useful as human and agricultural fungicides.

Abstract: Compounds of the formula: ##STR1## wherein Ar is phenyl substituted by from 1 to 3 substituents, each substituent being independently halo or CF.sub.3 ;n is 0 or 1; andR is a phenyl or a phenyl group substituted by from 1 to 3 substituents, each substituent being independently halo, CF.sub.3, C.sub.1 -C.sub.4 alkoxy, C.sub.2 -C.sub.5 alkoxy-carbonyl or C.sub.1 -C.sub.4 alkylthio, or a 5 or 6 membered aromatic heterocyclic group which may optionally be substituted;and their pharmaceutically acceptable salts are antifungal agents useful in combatting fungal infections in humans.

Abstract: Compounds of the formula ##STR1## a pharmaceutically or agriculturally acceptable salt thereof, wherein R is 5-chloro-2-pyridyl or phenyl optionally substituted by one to three substituents, each independently selected from F, Cl, Br, I, CF.sub.3, C.sub.1 -C.sub.4 alkyl and C.sub.1 -C.sub.4 alkoxy; R.sup.1 is CONR.sup.2 R.sup.3 where either(a) R.sup.2 is H or C.sub.1 -C.sub.4 alkyl and R.sup.3 is C.sub.2 -C.sub.4 alkanoyl or optionally substituted benzoyl; or(b) R.sup.2 and R.sup.3 are each (C.sub.1 -C.sub.4 alkoxy)carbonyl; and R.sup.4 and R.sup.5 are each H or CH.sub.3 ; methods for their use in combating fungal infections in plants, seeds and animals, including humans, and pharmaceutical and agricultural compositions containing them.

Abstract: Compounds of the formula ##STR1## or a pharmaceutically or agriculturally acceptable acid addition salt thereof wherein m and n are independently 0, 1, 2, 3 or 4; method for their use in combatting fungal infections in plants, seeds and animals, including humans; and pharmaceutical and agricultural compositions containing said compounds or salts.

Abstract: Compounds of the general formula: ##STR1## wherein Ar is dichlorophenyl and Het is 1-methyltetrazol-5-yl, 1,2,4-triazol-3-yl, 1-methyl-1,2,4-triazol-3-yl, 2-methyl-1,2,4-triazol-3-yl, 4-methyl-1,2,4-triazol-3-yl, imidazol-2-yl or 1-methylimidazol-2-yl and their pharmaceutically acceptable acid addition salts are antifungal agents in humans and other animals.

Abstract: Compounds of the general formula ##STR1## or a pharmaceutically acceptable acid addition salt thereof, wherein R is naphthyl, biphenylyl, phenyl or substituted phenyl; and R.sup.1 is ##STR2## where X is O or S, R.sup.2 is H, or C.sub.1 -C.sub.4 alkyl and R.sup.3 is H, C.sub.1 -C.sub.4 alkyl, C.sub.3 -C.sub.6 cycloalkyl, optionally mono- or disubstituted phenyl, benzyl or Het and Het is pyridyl, pyrimidinyl or pyrazinyl; said substituents being halo, CF.sub.3, C.sub.1 -C.sub.4 alkyl, C.sub.1 -C.sub.4 alkoxy or hydroxy, or R.sup.2 and R.sup.3 taken together complete a 1-pyrrolidinyl or piperidino ring; methods for their use in combatting fungal infections in plants and animals, including humans; pharmaceutical and agricultural compositions containing them and intermediates useful in their preparation.

Abstract: Compounds of the formula ##STR1## wherein X is an amine function and R is substituted phenyl and their pharmaceutically acceptable salts are useful antifungal agents in animals, including man.

Abstract: A series of novel 2-aryl-1-(imidazol-1-yl)-8-(4-piperazin-1-ylphenoxy)octan-2-ol derivatives has been prepared, including their pharmaceutically acceptable acid addition salts. These particular compounds are useful in therapy as antifungal agents for the treatment of various topical, mucosal and systemic fungal infections in animals, including humans. Preferred member compounds include 2-(2,4-dichlorophenyl)-1-(imidazol-1-yl)-8-[4-ethylpiperazin-1-yl)phenoxy] octan-2-ol, 2-(2,4-dichlorophenyl)-1-(imidazol-1-yl)-8-[4-(4-n-propylpiperazin-1-yl)ph enoxy]octan-2-ol and 2-(2,4-dichlorophenyl)-1-(imidazol-1-yl)-8-[4-(4-isopropylpiperazin-1-yl)p henoxy]octan-2-ol, respectively. Methods for preparing these compounds from known starting materials are provided.

Abstract: 2-(2,4-Difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol and its pharmaceutically acceptable acid addition salts are disclosed. This particular bis-triazole derivative and its aforesaid salts are useful for treating fungal infections in animals, including humans. Methods for preparing these compounds from known starting materials are provided.

Abstract: Certain 2-deoxystreptamine aminoglycoside antibiotics, substituted on the 1-amino group by an alkyl group bearing one or more hydroxy groups, are useful antibacterial agents. The 2-deoxystreptamine aminoglycoside compounds which are substituted in this manner include the kanamycins, the gentamicins, tobramycin, ribostamycin, the neomycins, and 6'-N-alkyl derivatives thereof.

Abstract: A notepad attachment for mounting a notepad onto the hub of a steering wheel of a motor vehicle includes a platform member with a recess therein, and an annular resilient mounting cushion which is disposed between the platform member and the hub of the steering wheel. An elastic cord or lace is threaded through annularly spaced holes in the base of the recess and round the back of the spoke or spokes of the wheel. The notepad is disposed in the recess of the platform, and a further recess is provided in the platform member for a pencil which is anchored to the platform member by a suitable cord.

Abstract: Derivatives of kanamycin A, which have an acyl protecting group on the C-3" and C-6' amino groups, and optionally have a benzyl protecting group on the C-3 amino group, are useful intermediates for the preparation of 1-N-(.omega.-amino-2-hydroxyalkyl) derivatives of kanamycin A. Derivatives of kanamycin B, which have an acyl protecting group on the C-2', C-3" and C-6' amino groups, and optionally have a benzyl protecting group on the C-3 amino group, are useful intermediates for the preparation of 1-N-(.omega.-amino-2-hydroxyalkyl) derivatives of kanamycin B. Certain of the partially protected kanamycin A and kanamycin B derivatives of this invention are useful for preparing 1-N-(.omega.-amino-2-hydroxyalkanoyl) derivatives of kanamycin A and B. 1-N-(.omega.-Amino-2-hydroxyalkyl) and 1-N-(.omega.-amino-2-hydroxyalkanoyl)derivatives of kanamycin A and B are known antibacterial agents.

Abstract: Novel diamines containing an aromatic nucleus which are useful as antiviral agents in vertebrates are disclosed.

Abstract: Novel diamines containing an aromatic nucleus which are useful as antiviral agents in vertebrates are disclosed.

Abstract: Novel benzyl- and phenylethylamines useful as anti-viral agents are claimed as well as a process and a pharmaceutical composition for combating viral infections.

Abstract: Novel alkyl esters of quinoxaline-di-N-oxide-2-carboxylic acid substituted on the alkyl portion of the ester by hydroxy, acyloxy, N-alkyl carbamyloxy, dialkylaminoacyloxy, carboxyacyloxy, alkoxycarbonyloxy, haloacyloxy, amino and mono- and disubstituted amino, useful as antibacterial agents and in promoting growth and improving feed efficiency of animals in general.

Abstract: Novel diamines containing an aromatic nucleus which are useful as antiviral agents in vertebrates are disclosed.

Abstract: Novel benzyl- and phenylethylamines useful as anti-viral agents are claimed as well as a process and a pharmaceutical composition for combating viral infections.