Abstract: An oral health care device is activated. The oral health care device includes a fluid reservoir and a pump to provide fluid included in the fluid reservoir to a plurality of fluid nozzles. A sensed value is used to determine whether the fluid is being provided to the plurality of fluid nozzles via the pump. A motor associated with the pump is stopped based on whether the fluid is being provided to the plurality of fluid nozzles via the pump.

Abstract: A method includes receiving physiological data associated with a user during at least a portion of an initial sleep session. The method also includes receiving demographic information associated with the user. The method also includes receiving subjective feedback associated with at least a portion of the initial sleep session from the user. The method also includes determining a profile for the user based at least in part on the physiological data associated with the user, the demographic information associated with the user, and the subjective feedback for the initial sleep session. The method also includes determining a recommended therapy for the user and one or more recommended parameters for the recommended therapy based at least in part on a comparison between the determined profile for the user and profiles associated with a plurality of other users.

Abstract: Systems and methods for using stratigraphic heat maps to steer a well being drilled. Data from one or more offset wells can be provided to a computer system and used with data from a well being drilled to generate one or more stratigraphic heat maps during the drilling of the subject well. The stratigraphic heat maps can be displayed and used to determine the location of the wellbore relative to one or more geological formations, including one or more target formations or within a target formation. Based on the use of the heat maps and the location of the wellbore relative to a target, the drill plan can be adjusted or updated and/or one or more drilling parameters or operations may be adjusted to drill the wellbore, such as to drill the wellbore to the target or to maximize the length of the wellbore within a target zone.

Abstract: Provided are novel prodrugs of treprostinil, as well as methods of making and methods of using these prodrugs.

Abstract: The network device may be configured to define or update a scene for controlling a zone in a certain area or location of a load control system. For example, the load control system may be installed in a residential home or building. At least one lighting control device that is configured to control a corresponding lighting load may be assigned to each of the one or more zones. The network device may be configured to display one or more graphical user interfaces that a user of the network device may interact with to define or update a scene. The network device may also be configured to display one or more graphical user interfaces that a user of the network device may interact with to define or update natural show functionality. After a scene and/or natural show have been configured, the may enabled or activated in response to a triggering event.

Abstract: In some embodiments, a method for processing an optical fiber includes: drawing an optical fiber through a draw furnace, conveying the optical fiber through a flame reheating device downstream from the draw furnace, wherein the flame reheating device comprises one or more burners each comprising: a body having a top surface and an opposing bottom surface, an opening within the body extending from the top surface through the body to the bottom surface, wherein the optical fiber passes through the opening, and one or more gas outlets within the body; and igniting a flammable gas provided by the one or more gas outlets to form a flame encircling the optical fiber passing through the opening, wherein the flame heats the optical fiber by at least 100 degrees Celsius at a heating rate exceeding 10,000 degrees Celsius/second.

Abstract: A system performs static program analysis with artifact reuse. The system identifies artifacts associated with the software program being analyzed. The system processes the identified artifacts for performing static program analysis and transmits either the artifacts or identifiers for the artifacts to a second processing device for performing program analysis. The second processing device receives the artifacts and uses the received identifiers to retrieve the artifacts from a networked storage system. The second device also retrieves stored summaries of previous program analysis from the networked storage system. The program analysis uses the retrieved artifacts to generate work units for static program analysis. The analysis is performed only for those work units that are determined to remain unchanged from previous static program analysis cycles.

Abstract: A tire protection sprinkler including a frame body having an inlet, an outlet, defining an internal passageway extending between the inlet and the outlet along a sprinkler axis. A dome shaped deflector member is centered, axially aligned with the sprinkler axis, and spaced from the outlet. The deflector member has an outer surface and an inner surface that preferably includes: a peripheral region, a central region and an intermediate region. The intermediate region includes a primary deflecting surface, and a secondary deflecting surface that is surrounded by the primary deflecting surface The deflector member provides for generation of a non-circular spray pattern defined by four zones of fluid density concentrically formed about the sprinkler axis.

Abstract: Embodiments described herein are directed to an annotation system having a remote processor, and a client processor in data communication with the remote processor. The client processor is adapted to send a first request for an electronic file to the remote processor, receive the electronic file from the remote processor, define at least one new annotation about the electronic file, and define at least one anchor associated with the at least one annotation. The at least one of the remote processor and the client processor is adapted to store the at least one anchor and the at least one annotation in an annotation file that is separate from the electronic file.

Abstract: The invention provides a neck-worn sensor (referred to herein as the ‘necklace’) that is a single, body-worn system that measures the following parameters from an ambulatory patient: heart rate, pulse rate, pulse oximetry, respiratory rate, temperature, thoracic fluid levels, stroke volume, cardiac output, and a parameter sensitive to blood pressure called pulse transit time. From stroke volume, a first algorithm employing a linear model can estimate the patient's pulse pressure. And from pulse pressure and pulse transit time, a second algorithm, also employing a linear algorithm, can estimate systolic blood pressure and diastolic blood pressure. Thus, the necklace can measure all five vital signs along with hemodynamic parameters. It also includes a motion-detecting accelerometer, from which it can determine motion-related parameters such as posture, degree of motion, activity level, respiratory-induced heaving of the chest, and falls.

Abstract: The present disclosure discloses systems and methods for measuring the bladder volume of a patient. An ultrasound transducer array may be used to transmit electrical pulses and receive the backscattered pulses that can be analyzed to develop a representation of the patients bladder. The backscattered ultrasound signals may be amplified, converted, and processed by circuitry and computer software to develop an axial position of the anterior and posterior bladder walls. Bladder volume measurements derived from the patients bladder may then be wirelessly transmitted to a display device for assessment by a healthcare provider. The ultrasound transducer array portion of the device may be held in place between the patients peritoneum and pubis by an elastic strap or a belt to ensure proper positioning.

Abstract: The present disclosure relates to a dose detection system for use with a medication delivery device in which a dose setting member rotates relative to an actuator during dose delivery. The dose detection system includes a module which is removably attached to the medication delivery device. The module includes a rotation sensor attached to the actuator during dose delivery. A sensed element is attached to the dose setting member and includes surface features detectable by the rotation sensor. The rotation sensor comprises a following member including a contact portion resting against and spring-biased in the direction of the surface features. The contact surface is positioned to move over the surface features during rotation of the sensed element, and the rotation sensor is responsive to the movement of the contact portion over the surface features to detect the rotation of the dose setting member.

Abstract: Systems and methods for using stratigraphic heat maps to steer a well being drilled. Data from one or more offset wells can be provided to a computer system and used with data from a well being drilled to generate one or more stratigraphic heat maps during the drilling of the subject well. The stratigraphic heat maps can be displayed and used to determine the location of the wellbore relative to one or more geological formations, including one or more target formations or within a target formation. Based on the use of the heat maps and the location of the wellbore relative to a target, the drill plan can be adjusted or updated and/or one or more drilling parameters or operations may be adjusted to drill the wellbore, such as to drill the wellbore to the target or to maximize the length of the wellbore within a target zone.

Abstract: Provided are novel prodrugs of treprostinil, as well as methods of making and methods of using these prodrugs.

Abstract: Assemblies for supporting a load relative to a roof of a vehicle, and vehicle roof tray assemblies are disclosed. Disclosed assemblies include an elongate member and an engaging mechanism. The elongate member defines a support surface for supporting the load, and has a pair of opposed, diverging retention surfaces extending away from the support surface. The engaging mechanism is configured to abut the retention surfaces to engage the elongate member. A slat for a vehicle roof tray is also disclosed.

Abstract: The invention provides a neck-worn sensor (referred to herein as the ‘necklace’) that is a single, body-worn system that measures the following parameters from an ambulatory patient: heart rate, pulse rate, pulse oximetry, respiratory rate, temperature, thoracic fluid levels, stroke volume, cardiac output, and a parameter sensitive to blood pressure called pulse transit time. From stroke volume, a first algorithm employing a linear model can estimate the patient's pulse pressure. And from pulse pressure and pulse transit time, a second algorithm, also employing a linear algorithm, can estimate systolic blood pressure and diastolic blood pressure. Thus, the necklace can measure all five vital signs along with hemodynamic parameters. It also includes a motion-detecting accelerometer, from which it can determine motion-related parameters such as posture, degree of motion, activity level, respiratory-induced heaving of the chest, and falls.

Abstract: Systems and methods for automated filtering and normalization of logging data for improved drilling performance may enable smoothing and amplitude scaling of log data for meaningful comparison and analysis without scaling artefacts. The logging data may be collected from downhole sensors or may be recorded by a control system used for drilling. A computer implemented method may enable industrial scale automated filtering and normalization of logging data, including calibration to a known standard. In particular, the filtering and normalization may be used for stratigraphic analysis to correlate true vertical depth to measured depth along a wellbore.

Abstract: The invention provides a sensor for measuring both impedance and ECG waveforms that is configured to be worn around a patient's neck. The sensor features 1) an ECG system that includes an analog ECG circuit, in electrical contact with at least two ECG electrodes, that generates an analog ECG waveform; and 2) an impedance system that includes an analog impedance circuit, in electrical contact with at least two (and typically four) impedance electrodes, that generates an analog impedance waveform. Also included in the neck-worn system are a digital processing system featuring a microprocessor, and an analog-to-digital converter. During a measurement, the digital processing system receives and processes the analog ECG and impedance waveforms to measure physiological information from the patient. Finally, a cable that drapes around the patient's neck connects the ECG system, impedance system, and digital processing system.