Abstract: The invention relates to the use of flibanserin, or a pharmaceutically acceptable acid addition salt thereof, for the treatment of disorders of sexual desire.

Abstract: The invention provides a neck-worn sensor that is a single, body-worn system that measures the following parameters from an ambulatory patient: heart rate, pulse rate, pulse oximetry, respiratory rate, temperature, thoracic fluid levels, stroke volume, cardiac output, and a parameter sensitive to blood pressure called pulse transit time. From stroke volume, a first algorithm employing a linear model can estimate the patient's pulse pressure. And from pulse pressure and pulse transit time, a second algorithm, also employing a linear algorithm, can estimate systolic blood pressure and diastolic blood pressure. Thus, the sensor can measure all five vital signs along with hemodynamic parameters. It also includes a motion-detecting accelerometer, from which it can determine motion-related parameters such as posture, degree of motion, activity level, respiratory-induced heaving of the chest, and falls.

Abstract: A sprayed-in-place framed wall is disclosed, comprised of a cementitious face and backing layers and a polyurethane foam insulation layer that bonds the cementitious layers to a separate wall frame. Stationary walls are constructed by spraying the materials against one-sided, vertical wall forms positioned around an erected, exterior wall frame. The cementitious materials are restrained by stays. The wall forms may have indentations to enable the resulting wall face to have protrusions such as moulding, bands, quoins and cornices, which may be a different color that the surrounding flat wall face.

Abstract: A sprayed-in-place framed wall is disclosed, comprised of a cementitious face and backing layers and a polyurethane foam insulation layer that bonds the cementitious layers to a separate wall frame. Stationary walls are constructed by spraying the materials against one-sided, vertical wall forms positioned around an erected, exterior wall frame. The cementitious materials are restrained by stays. The wall forms may have indentations to enable the resulting wall face to have protrusions such as moulding, bands, quoins and cornices, which may be a different color that the surrounding flat wall face.

Abstract: Provided are novel prodrugs of treprostinil, as well as methods of making and methods of using these prodrugs.

Abstract: A receptacle runner assembly including a pair of opposed sub-assemblies configured to be arranged in a spaced relationship at opposed sides of the receptacle, each sub-assembly including a runner configured to be carried along a first track to be movable in a first direction, a first linkage being pivotally connectable to each of the receptacle and the runner, a bearing securable relative to the receptacle, and a bearing surface configured to be arranged, in use, to extend transverse to the first direction to allow carrying the bearing, wherein the bearings and bearing surfaces are configured to cooperate to displace the receptacle in a direction perpendicular to the first direction while the runners are moving in the first direction.

Abstract: The invention provides a sensor for measuring both impedance and ECG waveforms that is configured to be worn around a patient's neck. The sensor features 1) an ECG system that includes an analog ECG circuit, in electrical contact with at least two ECG electrodes, that generates an analog ECG waveform; and 2) an impedance system that includes an analog impedance circuit, in electrical contact with at least two (and typically four) impedance electrodes, that generates an analog impedance waveform. Also included in the neck-worn system are a digital processing system featuring a microprocessor, and an analog-to-digital converter. During a measurement, the digital processing system receives and processes the analog ECG and impedance waveforms to measure physiological information from the patient. Finally, a cable that drapes around the patient's neck connects the ECG system, impedance system, and digital processing system.

Abstract: Systems and methods for automated filtering and normalization of logging data for improved drilling performance may enable smoothing and amplitude scaling of log data for meaningful comparison and analysis without scaling artefacts. The logging data may be collected from downhole sensors or may be recorded by a control system used for drilling. A computer implemented method may enable industrial scale automated filtering and normalization of logging data, including calibration to a known standard. In particular, the filtering and normalization may be used for stratigraphic analysis to correlate true vertical depth to measured depth along a wellbore.

Abstract: This invention is an additively manufactured wall panel using computer aided design (CAD) and computer aided manufacturing (CAM) to design and manufacture multi-colored and multi-layered wall panels. This results in a variety of highly attractive, multi-colored wall panel faces ranging from brick, colored grout lines and multi-colored stones to multi-colored geometric designs. The design and manufacturing process greatly reduces the amount of precast cementitious materials by efficiently using higher quality materials. This reduces cost and weight while simultaneously producing a much more comprehensive, multi-functional wall panel complete with an interior frame, exterior insulation and an air, vapor and moisture barriers.

Abstract: Systems and methods for using stratigraphic heat maps to steer a well being drilled. Data from one or more offset wells can be provided to a computer system and used with data from a well being drilled to generate one or more stratigraphic heat maps during the drilling of the subject well. The stratigraphic heat maps can be displayed and used to determine the location of the wellbore relative to one or more geological formations, including one or more target formations or within a target formation. Based on the use of the heat maps and the location of the wellbore relative to a target, the drill plan can be adjusted or updated and/or one or more drilling parameters or operations may be adjusted to drill the wellbore, such as to drill the wellbore to the target or to maximize the length of the wellbore within a target zone.

Abstract: A retrofitable retractable screen system for use with windows or doors. Instead of using a spring based tensioning arrangements to rewind the screen onto the roller assembly, the arrangement uses a pulley located on the spindle, around which is wrapped a cord. A guide assembly guides the cord around a tension adjustment arrangement that adjusts the tension in the cord as the screen is wound and unwound from the spindle to provide a smooth mechanism to extend and retract the screen. When the screen is extended, pushing the edge of the screen to force retraction of the screen is translated into a pulling action on the cord to unwind the cord off a pulley, which drives rotation of the spindle to wind the screen back on. Conversely, pulling the distal edge to extend the screen rotates the spindle and pulley to wind the cord back onto the pulley.

Abstract: The invention relates to the use of flibanserin, or a pharmaceutically acceptable acid addition salt thereof, for the treatment of disorders of sexual desire.

Abstract: This invention is an additively manufactured wall panel using computer aided design (CAD) and computer aided manufacturing (CAM) to design and manufacture multi-colored and multi-layered wall panels. This results in a variety of highly attractive, multi-colored wall panel faces ranging from brick, colored grout lines and multi-colored stones to multi-colored geometric designs. The design and manufacturing process greatly reduces the amount of precast cementitious materials by efficiently using higher quality materials. This reduces cost and weight while simultaneously producing a much more comprehensive, multi-functional wall panel complete with an interior frame, exterior insulation and an air, vapor and moisture barriers.

Abstract: The invention provides a sensor for measuring both impedance and ECG waveforms that is configured to be worn around a patient's neck. The sensor features 1) an ECG system that includes an analog ECG circuit, in electrical contact with at least two ECG electrodes, that generates an analog ECG waveform; and 2) an impedance system that includes an analog impedance circuit, in electrical contact with at least two (and typically four) impedance electrodes, that generates an analog impedance waveform. Also included in the neck-worn system are a digital processing system featuring a microprocessor, and an analog-to-digital converter. During a measurement, the digital processing system receives and processes the analog ECG and impedance waveforms to measure physiological information from the patient. Finally, a cable that drapes around the patient's neck connects the ECG system, impedance system, and digital processing system.

Abstract: The present invention provides a means for powered, programmable transformation of a bicycle to fit a given cyclist for a given condition while riding. It comprises a computer/app and actuators to perform all adjustments while riding, that is programmable to recall fit information and/or to follow a fit algorithm that will transform a bicycle to match a particular rider's best fit for a particular condition such as climbing, descending, sprinting, etc. It also may adjust fit in response to “on-the-fly” rider commands, sensor inputs, and/or data from other devices.

Abstract: Disclosed are methods and systems for characterizing and analyzing an electronic system design including a parallel interface. Some methods and systems identify an electronic design including a parallel interface, determine a single circuit representation including the parallel interface from the electronic design, and analyze the parallel interface to determine waveform responses of the parallel interface by using channel analysis techniques without performing circuit simulations.

Abstract: An apparatus and related process for producing a high-strength weld between two glass components. Chucks clamp and move respective first ends of the glass components toward each other inside an enclosure, where the second ends are heated, softened, and welded together in a weld zone. The enclosure has layers of stacked quartz glass bricks and allows the weld zone to cool slowly and avoid stress. A propane quartz melting torch directs a flame inside the enclosure and toward the second ends as the glass components move toward each other. The flame softens the second ends and creates substantially smooth polished surfaces in the weld zone having an increased hydroxide content. At least 80% of the weld zone has a hydroxide content greater than about 10 ppm average in a 10 ?m depth from the surface and the tensile strength of the weld zone is above about 10 MPa.

Abstract: A fire protection sprinkler including a frame body having an inlet, an outlet, defining an internal passageway extending between the inlet and the outlet along a sprinkler axis. A dome shaped deflector member is centered, axially aligned with the sprinkler axis, and spaced from the outlet. The deflector member has an outer surface and an inner surface that preferably includes: a peripheral region, a central region and an intermediate region. The intermediate region includes a primary deflecting surface, and a secondary deflecting surface that is surrounded by the primary deflecting surface. The deflector member provides for generation of a non-circular spray pattern defined by four zones of fluid density concentrically formed about the sprinkler axis.

Abstract: Assemblies for supporting a load relative to a roof of a vehicle, and vehicle roof tray assemblies are disclosed. Disclosed assemblies include an elongate member and an engaging mechanism. The elongate member defines a support surface for supporting the load, and has a pair of opposed, diverging retention surfaces extending away from the support surface. The engaging mechanism is configured to abut the retention surfaces to engage the elongate member. A slat for a vehicle roof tray is also disclosed.

Abstract: A system and method are disclosed for the collection and aggregation of data from contributing members of a community, such as health-related, personal, genomic, medical, and other data of interest for individuals and populations. Contributors become members of a community upon creation of an account and providing of data or files. The data is received and processed, such as to analyze, structure, perform quality control, and curate the data. Value or shares in one or more community databases are computed and attributed to each contributing member. The data is controlled to avoid identification or personalization. Steps are taken to determine incompleteness and incorrectness of the data, and the data may be improved or completed automatically, based upon interaction with members, additional contributions of data, and so forth.