Patents by Inventor Kenneth S. Rehder

Kenneth S. Rehder has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Prenylation inhibitors and methods of their synthesis and use
    Publication number: 20040053970
    Abstract: The present invention is directed to compounds useful in the treatment of diseases associated with prenylation of proteins and pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising same, and to methods for inhibiting protein prenylation in an organism using the same.
    Type: Application
    Filed: August 22, 2003
    Publication date: March 18, 2004
    Applicant: PPD Discovery, Inc.
    Inventors: Bradley B. Brown, Kenneth S. Rehder
  • Prenylation inhibitors containing dimethylcyclobutane and methods of their synthesis and use
    Patent number: 6664277
    Abstract: The present invention is directed to compounds useful in the treatment of diseases associated with prenylation of proteins and pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising same, and to methods for inhibiting protein prenylation in an organism using the same.
    Type: Grant
    Filed: January 3, 2003
    Date of Patent: December 16, 2003
    Assignee: PPD Discovery, Inc.
    Inventors: Bradley B. Brown, Kenneth S. Rehder, Jon-Paul Strachan, Jeron H. Eaves, Christopher T. Lowden
  • Prenylation inhibitors and methods of their synthesis and use
    Patent number: 6649638
    Abstract: The present invention is directed to compounds useful in the treatment of diseases associated with prenylation of proteins and pharmaceutically acceptable salts thereof, to pharmaceutical compositions comprising same, and to methods for inhibiting protein prenylation in an organism using the same.
    Type: Grant
    Filed: January 3, 2003
    Date of Patent: November 18, 2003
    Assignee: PPD Discovery, Inc.
    Inventors: Bradley B. Brown, Kenneth S. Rehder
  • Substituted heterocyclic compounds
    Publication number: 20030176447
    Abstract: Disclosed are novel heterocyclic derivatives, useful for the treatment of various disease states, in particular cardiovascular diseases such as atrial and ventricular arrhythmias, intermittent claudication, Prinzmetal's (variant) angina, stable and unstable angina, exercise induced angina, congestive heart disease, and myocardial infarction. The compounds are also useful in the treatment of diabetes, and for increasing HDL plasma levels in mammals.
    Type: Application
    Filed: January 17, 2003
    Publication date: September 18, 2003
    Inventors: Prabha Ibrahim, Kevin Shenk, Elfatih Elzein, Venkata Palle, Jeff Zablocki, Kenneth S. Rehder