Abstract: Described herein are modified fibroblast growth factors (FGFs), pharmaceutical compositions, ophthalmic formulations, and medicaments that include such modified FGFs, and methods of using such modified FGFs to treat ocular diseases, disorders, or conditions.

Abstract: Systems and methods which provide for activation of postage indicia at a point of sale are shown. In operation according to embodiments, unassigned (e.g., not yet activated or not yet representing postage value) tokens (e.g., IBI barcodes) suitable for later use as postage indicia are distributed to various point of sale locations, such as retail locations, consumer kiosks, vending machines, etc. and made available for purchase by users. Upon purchase, at a point of sale, such unassigned tokens are preferably activated as valid or “live” postage indicia. Thereafter, the postage indicia may be used to post mail items.

Abstract: A workflow generation system comprising a first device with a computing unit, a memory unit and a first communication unit, and a plurality of software agents used with electronic apparatuses comprising at least one measuring device, wherein each software agent is on an electronic apparatus or an communication module connected to the electronic apparatuses, wherein each software agent exchanges data with the electronic apparatus the first device receives a measuring task and performs a workflow generation process to receive from agents task-specific data of the apparatuses, the task- specific data information about properties of the respective apparatus, to assess task-specific capabilities associated with each of the apparatuses, generate, based on the task and on the capabilities, an optimized workflow for performing the task including workflow data allowing the respective apparatus to perform the task, and to provide the workflow data to the software agents of the involved apparatuses.

Abstract: Devices, methods, systems and procedures for localized, targeted treatment of angiogenic-based therapy in at least one region of interest in one or more layers of cardiac tissue. Various methods can include diagnosing a patient with ischemic heart disease or “at-risk” of manifesting ischemic heart disease, placing the patient into a specific angiogenic-based treatment therapy group, collecting image data, confirming image data and other diagnostic test results, developing a preoperative plan to target region of interest, inserting the catheter into a heart chamber, monitoring the distal end of the catheter tip within the heart on a visual display, contacting at least one layer of cardiac tissue, creating one or more channels in the heart tissue and/or administering the angiogenic-based therapy.

Abstract: A workflow generation system comprising a first device with a computing unit, a memory unit and a first communication unit, and a plurality of software agents used with a plurality of electronic apparatuses comprising at least one measuring device, wherein each software agent is installable on an electronic apparatus of the plurality of electronic apparatuses and exchanges data with the electronic apparatus, wherein the first device receives a measuring task and performs a workflow generation process to generate a workflow for performing the task involving one or more of the apparatuses, to generate workflow data allowing a respective apparatus to perform a part of the task, and to provide the workflow data to the software agents of the involved apparatuses, and provide configuration data to the software agents to reconfigure the respective apparatus for providing functions for performing the part of the task by the respective apparatus.

Abstract: Devices, methods, systems and procedures for localized, targeted treatment of angiogenic-based therapy in at least one region of interest in one or more layers of cardiac tissue. Various methods can include diagnosing a patient with ischemic heart disease or “at-risk” of manifesting ischemic heart disease, placing the patient into a specific angiogenic-based treatment therapy group, collecting image data, confirming image data and other diagnostic test results, developing a preoperative plan to target region of interest, inserting the catheter into a heart chamber, monitoring the distal end of the catheter tip within the heart on a visual display, contacting at least one layer of cardiac tissue, creating one or more channels in the heart tissue and/or administering the angiogenic-based therapy.

Abstract: An apparatus, method and system for providing and dispensing various hand care alternatives from a common point of dispension, such as a faucet, for standardizing the hand care, washing, sanitizing, and drying process is disclosed. Included is a liquid flow path having an inlet in fluid communication with a liquid source and an outlet in fluid communication with a user reception point. A secondary flow path has an inlet in communication with one or more hand care alternatives and an outlet in communication with the user reception point. A user-perceivable output provides notification of the hand care operation being provided at the user reception point.

Abstract: A computer system for controlling access to digital data and algorithms, including a multitude of local systems provided at a plurality of remote locations. At least a first subset of the multitude of local systems comprises at least one data acquisition device adapted to generate and provide raw digital data. At least a second subset of the multitude of local systems comprises at least one data processing unit having a memory with a memory capacity and a processor with a computing capacity to process raw digital data to generate processed digital data to be presented to one or more of a plurality of users of the system. The system also includes a filter system, wherein at least one filter is assigned at each local system, each filter having a filter setting for restricting and prohibiting data transfer between the assigned local system and other local systems.

Abstract: A system for dissolving solid chemical may include three reservoirs positioned in a vertically stacked arrangement. A solid chemical reservoir configured to receive solid chemical to be dissolved may be nested in a solution generator reservoir into which water is introduced to erode the solid chemical. A dissolved chemical reservoir can be positioned under the solid chemical reservoir and the solution generator reservoir. The dissolved chemical reservoir can store solution generated using the system. In some examples, a recirculation circuit is used to recirculate water introduced into the solution generator reservoir until a solution having a target concentration of the chemical being dissolved is achieved. The recirculation circuit may include a recirculation line having an outlet aimed at the bottom wall of the solid chemical reservoir.

Abstract: A strainer basket system may include a reservoir in which a strainer basket is positioned and a chemical dispensing docking station. The chemical dispensing docking station may have a cavity that receives a container of chemical to be dispensed and a retention mechanism that is configured to mechanically engage and retain the container of chemical, when inserted into the cavity. The docking station may also include a piercing member positioned to pierce the container of chemical as the container of chemical is inserted into the cavity, thereby releasing chemical into the reservoir and/or strainer basket.

Abstract: An exemplary embodiment of the present invention will provide a method using a computer, and a computer system, for providing image-customizing labels that are adapted for receiving computer-based, generic, value-bearing item indicia such as, for example, computer-based, generic, postage indicia. The exemplary embodiment of the present invention will comprise generating a display of a user interface screen that is adapted for receiving an order from a user for at least one image-customized label adapted for bearing a computer-based, generic, value-bearing item.

Abstract: A pest control device may include a bait support system. The bait support system may include a bait bar having a first end and a second end. An aperture in the pest control device may receive at least a portion of the first end of the bait bar. A locking mechanism may secure the second end so as to lock the bait bar to the pest control device. The bait bar may be locked to the pest control device when a lid of the pest control device is in an open configuration.

Abstract: An apparatus, method and system for providing and dispensing various hand care alternatives from a common point of dispension, such as a faucet, for standardizing the hand care, washing, sanitizing, and drying process is disclosed. Included is a liquid flow path having an inlet in fluid communication with a liquid source and an outlet in fluid communication with a user reception point. A secondary flow path has an inlet in communication with one or more hand care alternatives and an outlet in communication with the user reception point. A user-perceivable output provides notification of the hand care operation being provided at the user reception point.

Abstract: A material supply assembly includes a valve assembly having an outer valve member and an inner valve member rotatable relative to the outer valve member. A plurality of discharge seals may be provide between the outer valve member and the inner valve member, with one of the discharge seals extending around openings of the outer valve member or openings of the inner valve member. A first circumferential seal may also be provided. An engagement structure including a plurality of spaced apart vertical engagement projections and a plurality of complementary configured engagement recesses may be provided between the valve assembly and the base. A locking arm having a locking member may be provided with the locking member positioned in a locking receptacle. A projection engages the locking arm to move the locking member from the locking receptacle.

Abstract: A chemical dispensing system can include a docking stating that receives a reservoir containing chemical to be dispensed. The reservoir may have one or more retention tabs which are movable from a first position in which each tab extends radially across at least a portion of the bore to a second position in which each tab is offset relative to the bore. A user can engage the reservoir with the docking station, causing the one or more retention tabs on the reservoir to engage with one or more corresponding retention tab receiving regions. This can cause each retention tab to move from the first position to the second position, thereby dispensing chemical from the bore through a discharge aperture of the docking station. In this way, the contents of the reservoir may be dispensed without the user coming into physical content with the chemical in the reservoir.

Abstract: Techniques are described for switching streaming of media content between content delivery networks (CDNs) during mid-stream. An initial CDN can be used to stream the media content. The performance of a second CDN can be measured by requesting a fragment of the media content as a measurement or test fragment. Streaming of the media content can be switched to the second CDN if its performance is determined to be better than the initial CDN.

Abstract: The invention relates to systems and methods for the diagnosis, amelioration, and treatment of ischemic tissues in patients caused by and/or resulting from diminished microvascular blood flow. Patients suffering from ischemic tissue conditions can be categorized into specific subsets that are deemed to have a potential to respond to therapy. In particular, the invention includes various therapies involving stimulation of angiogenesis, vasculogenesis, arteriogenesis and/or neovascularization so as to increase perfusion of various tissues.

Abstract: Systems and methods which provide postage indicia using mobile communication handsets are shown. According to embodiments, users are enabled to introduce mail pieces into a mail delivery stream which are accepted as having activated, value comprising postage indicia associated therewith without the use of traditional metering systems, processor-based postage generation and printing systems, or even printers. Instead, a token comprising substantially unique identification information identifying a mail piece is activated as an activated token having postage value associated therewith using mobile communication handsets, such as a smart phone, network enabled personal digital assistant, etc. according to embodiments of the invention.

Abstract: The invention relates to systems and methods for the diagnosis, amelioration, and treatment of ischemic tissues in patients caused by and/or resulting from diminished microvascular blood flow. Patients suffering from ischemic tissue conditions can be categorized into specific subsets that are deemed to have a potential to respond to therapy. In particular, the invention includes various therapies involving stimulation of angiogenesis, vasculogenesis, arteriogenesis and/or neovascularization so as to increase perfusion of various tissues.

Abstract: A material supply assembly includes a valve assembly having an outer valve member and an inner valve member rotatable relative to the outer valve member. A base assembly includes an base structure and an actuator. An engagement structure is operative between the outer valve member and the actuator to prevent relative movement between the outer valve member and the actuator. A locking structure is operative between the inner valve member and the base structure to prevent relative movement between the inner valve member and the base structure. Movement of the actuator relative to the base structure moves the outer valve member relative to the inner valve member to operate the valve assembly.