Abstract: This invention relates to methods and compositions for the treatment of apoptotic cell-death. In particular the invention relates to Akt molecules and their use in inhibiting apoptotic cell-death in cardiomyocytes, skeletal myocytes and/or vascular endothelial cells. In view of these discoveries, Akt molecules can be used to inhibit apoptotic cell-death of any of the foregoing cells, and in particular, to treat conditions (e.g., myocardial infarction) that result in increased apoptotic cell-death of cardiomyocytes, skeletal myocytes and/or vascular endothelial cells.

Abstract: A garment comprising different portions having different performance characteristics. A preferred embodiment is a fishing shirt comprising: a body portion, said body portion being fabricated from a breathable, knitted fabric having a wicking finish; a collar portion and a yoke portion, said collar portion and said yoke portion being fabricated from a four-way stretch fabric having a wicking finish; a pair of lower sleeve portions, each of said lower sleeve portions being fabricated from a non-wicking, hydrophobic fabric; and an optional pair of underarm portions, each of said underarm portions being fabricated from a knit, anti-microbial fabric.

Abstract: The invention provides a method of detecting the presence of anti-MHC antibodies in a sample comprising contacting said sample with one or more recombinant MHC molecules or functionally equivalent variants, derivatives or fragments thereof and detecting the binding or absence of binding of antibodies to said recombinant MHC molecules.

Abstract: We have surprisingly discovered that adiponectin regulates angiogenesis and have shown that adiponectin is an effective agent at treating cardiac disorders. As a result of this discovery, the present invention provides methods for treatment of cardiac disorders and methods for stimulation of angiogenesis in tissues using adiponectin. In one preferred embodiment, the methods of the invention are used to treat complications of diabetes, such as ischemic limbs and hypertrophic cardiomyopathy.

Abstract: The current invention is a lid dispensing device and method of use comprising a base unit, a lid holder operatively connected to the base unit, a blade operatively mounted to the base which moves between a first position and a second position, a tab secured to the blade to aid in separating lids, the blade supporting a stack of lids by engaging a first lid in the stack of lids while the blade is in the first position, and the blade allowing the first lid to fall through an aperture in the blade away from the stack of lids, and still support the remaining stack of lids as the blade moves to the second position.

Abstract: The current invention is a lid dispensing device and method of use comprising a base unit, a lid holder operatively connected to the base unit, a blade operatively mounted to the base which moves between a first position and a second position, the blade supporting a stack of lids by engaging a first lid in the stack of lids while the blade is in the first position, and the blade allowing the first lid to fall through an aperture in the blade away from the stack of lids, and still support the remaining stack of lids as the blade moves to the second position.

Abstract: The current invention is a lid dispensing device and method of use comprising a base unit, a lid holder operatively connected to the base unit, a blade operatively mounted to the base which moves between a first position and a second position, the blade supporting a stack of lids by engaging a first lid in the stack of lids while the blade is in the first position, and the blade allowing the first lid to fall through an aperture in the blade away from the stack of lids, and still support the remaining stack of lids as the blade moves to the second position.

Abstract: Methods for easily manufacturing a foot-covering component of a stocking foot wader including an effective gravel guard, and a foot-covering component including a gravel guard manufactured by such methods are disclosed. Preferably, the gravel guard is connected to the exterior surface of the leg-covering member and below the interior connection between the foot-covering member and the leg-covering member to provide a substantially watertight connection between the foot-covering member and the leg-covering member.

Abstract: Methods for easily manufacturing a foot-covering component of a stocking foot wader including an effective gravel guard, and a foot-covering component including a gravel guard manufactured by such methods are disclosed. Preferably, the gravel guard is connected to the exterior surface of the leg-covering member and below the interior connection between the foot-covering member and the leg-covering member to provide a substantially watertight connection between the foot-covering member and the leg-covering member.

Abstract: An article of clothing with three-dimensional, molded pockets. Preferably, the molded pockets are constructed of a fabric/foam laminate that has been heat/compression molded. In a preferred embodiment, the molded pockets find utility in the containment of fly boxes and other accessories used in fly fishing. A method of manufacturing a garment with three-dimensional, molded pockets.

Abstract: A novel growth arrest homeobox gene has been discovered and the nucleotide sequences have been determined in both the rat and the human. The expression of the novel homeobox gene inhibits vascular smooth muscle cell growth. The growth arrest homeobox gene hereinafter referred to as the “Gax gene” and its corresponding proteins are useful in the study of vascular smooth muscle cell proliferation and in the treatment of blood vessel diseases that result from excessive smooth muscle cell proliferation, particularly after balloon angioplasty.

Abstract: A garment comprising different portions having different performance characteristics. A preferred embodiment is a fishing shirt comprising: a body portion, said body portion being fabricated from a breathable, knitted fabric having a wicking finish; a collar portion and a yoke portion, said collar portion and said yoke portion being fabricated from a four-way stretch fabric having a wicking finish; a pair of lower sleeve portions, each of said lower sleeve portions being fabricated from a non-wicking, hydrophobic fabric; and a pair of underarm portions, each of said underarm portions being fabricated from a knit, anti-microbial fabric.

Abstract: A novel growth arrest homeobox gene has been discovered and the nucleotide sequences have been determined in both the rat and the human. The expression of the novel homeobox gene inhibits vascular smooth muscle cell growth. The growth arrest homeobox gene hereinafter referred to as the “Gax gene” and its corresponding proteins are useful in the study of vascular smooth muscle cell proliferation and in the treatment of blood vessel diseases that result from excessive smooth muscle cell proliferation, particularly after balloon angioplasty.

Abstract: Methods for easily manufacturing a foot-covering component of a stocking foot wader including an effective gravel guard, and a foot-covering component including a gravel guard manufactured by such methods are disclosed. Preferably, the gravel guard is connected to the exterior surface of the leg-covering member and below the interior connection between the foot-covering member and the leg-covering member to provide a substantially watertight connection between the foot-covering member and the leg-covering member.

Abstract: This invention relates to methods and compositions for the treatment of conditions associated with vascular insufficiency, and to methods and compositions for screening assays to select agents that are useful for this purpose. In particular the invention relates to HMG CoA reductase inhibitors and their use in promoting angiogenesis in vivo and in activating Akt in vascular endothelial cells in vitro and in vivo.

Abstract: A novel growth arrest homeobox gene has been discovered and the nucleotide sequences have been determined in both the rat and the human. The expression of the novel homeobox gene inhibits vascular smooth muscle cell growth. The growth arrest homeobox gene hereinafter referred to as the “Gax gene” and its corresponding proteins are useful in the study of vascular smooth muscle cell proliferation and in the treatment of blood vessel diseases that result from excessive smooth muscle cell proliferation, particularly after balloon angioplasty.

Abstract: A novel growth arrest homeobox gene has been discovered and the nucleotide sequences have been determined in both the rat and the human. The expression of the novel homeobox gene inhibits vascular smooth muscle cell growth. The growth arrest homeobox gene hereinafter referred to as the “Gax gene” and its corresponding proteins are useful in the study of vascular smooth muscle cell proliferation and in the treatment of blood vessel diseases that result from excessive smooth muscle cell proliferation, particularly after balloon angioplasty.

Abstract: A novel growth arrest homeobox gene has been discovered and the nucleotide sequences have been determined in both the rat and the human. The expression of the novel homeobox gene inhibits vascular smooth muscle cell growth. The growth arrest homeobox gene hereinafter referred to as the “Gax gene” and its corresponding proteins are useful in the study of vascular smooth muscle cell proliferation and in the treatment of blood vessel diseases that result from excessive smooth muscle cell proliferation, particularly after balloon angioplasty.

Abstract: A novel growth arrest homeobox gene has been discovered and the nucleotide sequences have been determined in both the rat and the human. The expression of the novel homeobox gene inhibits vascular smooth muscle cell growth. The growth arrest homeobox gene hereinafter referred to as the “Gax gene” and its corresponding proteins are useful in the study of vascular smooth muscle cell proliferation and in the treatment of blood vessel diseases that result from excessive smooth muscle cell proliferation, particularly after balloon angioplasty.

Abstract: A novel growth arrest homeobox gene has been discovered and the nucleotide sequences have been determined in both the rat and the human. The expression of the novel homeobox gene inhibits vascular smooth muscle cell growth. The growth arrest homeobox gene hereinafter referred to as the “Gax gene” and its corresponding proteins are useful in the study of vascular smooth muscle cell proliferation and in the treatment of blood vessel diseases that result from excessive smooth muscle cell proliferation, particularly after balloon angioplasty.